US Food and Drug Administration: list

total designated products: 1749

Cumulartive Designated Products as of: 10/3/2007

Generic Name

Trade Name

Designated Indication

Valortim

Treatment of anthrax infection

(+/-)-7-[3-(4-acetyl-3-methoxy-2propylphenoxy)propoxy]-3,4-dihydro-8-propyl2H-1-benzopyran-2-carboxylic acid

Prevention of serious adverse events associated with vascular leak syndrome caused by Interleukin-2 therapy

(1R,2S) 6-bromo-alpha-[2(dimethylamino)ethyl]-2-methoxy-alpha-(1naphthyl)-beta-phenyl-3-quinolineethanol

Treatment of pulmonary tuberculosis (active disease)

(1S)-1-(9-deazahypoxanthin-9-yl)-1,4dideoxy-1,4-imino-D-ribitol-hydrochloride

Treatment of chronic lymphocytic leukemia and related leukemias to include prolymphocytic leukemia, adult T-cell leukemia, and hairy cell leukemia

(1S)-1-(9-deazahypoxanthin-9-yl)-1,4dideoxy-1,4-imino-D-ribitol-hydrochloride

Treatment of acute lymphoblastic leukemia

(1S)-1-(9-deazahypoxanthin-9-yl)-1,4dideoxy-1,4-imino-D-ribitol-hydrochloride

Treatment of T-cell non-Hodgkin's lymphoma

(2Z)-2-cyano-3-3hydroxy-N-[4(trifluoromethly)phenyl]-2-hepten-6-ynamide (3-[5-(2-fluoro-phenyl)-[1,2,4]oxadiazole-3-yl]benzoic acid

Prevention of acute rejection following kidney, heart, and liver tranplantation For use in the treatment of cystic fibrosis resulting fron a nonsense (premature stopcodon) mutation in the cystic bibrosis transmembrane conductance regulatory gene.

(3-[5-(2-fluoro-phenyl)-[1,2,4]oxadiazole-3-yl]benzoic acid)

Treatment of Muscular Dystrophy resulting from premature stop mutations in the dystrohin gene.

(3S)-3-(4-trifluoromethoxybenzyloxy)-6-nitro2H-3,4-dihydroimidazo[2,1-b]oxazine

Treatment of tuberculosis.

FK778

(3S)-3-[(2S)-2-({N-[2-tertbutyl)phenyl]carbamoyl}carbonylamino) propanoylamino]-4-oxo-5-(2,3,5,6tetrafluorophenoxy) pentanoci acid (4S)-4-ethyl-4-hydroxy-3,14-dioxo-3,4,12,14tetrahydro-1-H-pyrano[3?,4?:6,7]-indolizino[1,2-b]-quinoline-11-carbaldehyde O-(tertbutyl)-(E)-oxime

Gimatecan

Treatment malignant glioma

(6R,S)5,10-methylene-tetrahydrofolic acid

CoFactor

For use in combination with 5-fluorouracil for the treatment of patients with pancreatic cancer

(9-[N-(3-morpholinopropyl)-sulfonyl]-5,6dihydro-5-oxo-11-H-indeno [1,2-c] isoquinoline methanesulfonic acid (R)-2-methyl-6-nitro-2-{4-[4-(4trifluoromethoxyphenoxy)piperidin-1yl]phenoxymethyl}-2,3-dihydroimidazo[2,1b]oxazole

Treatment of patients undergoing solid organ transplantation.

Prevention of post-operative complications of aortic anuerysm surgical repair

Treatment of pulmonary tuberculosis.

(R)-N-[2-(6-chloro-5-methoxy-1H-indol-3yl)propyl]acetamide

Treatment of circadian rhythm sleep disorders in blind people with no light perception

(R)-N-[2-(6-Chloro-methoxy-1H-indol3yl)propyl]acetamide

Treatment of neuroleptic-induced tardive dyskinesia in schizophrenia patients

(UDU-stereoisomer of c-UJUun UNU-terminal UkUnhibitor)

Treatment of acute sensorineural hearing loss

[5,10,15,20-tetrakis(1,3-diethylimidazolium-2yl)porphyrinato] manganese(III)pentachloride 1,1'-[1,4-phenylenebis(methylene)-bis1,4,8,11-tetraazacyclotetradecan

Treatment of Amyotrophic Lateral Sclerosis For use to improve the yield of progentor cells in the apheresis product for subsequest stem cell transplantation following myelosuppressive or myeloablative chemotherapy

1,2-bis(methylsulfonyl)-1-(2-chloroethyl)-2[(methylamino)carbonyl]hydrazine

Cloretazine

1,5-(Butylimino)-1,5 dideoxy,D-glucitol

111Indium pentetreotide

Treatment of Fabry's disease.

SomatoTher

166Ho-DOTMP

17 a-Hydroxyprogesterone caproate

Treatment of acute myelogenous leukemia

Treatment of somatostatin receptor positive neuroendocrine tumors.

Treatment of multiple myeloma.

Gestiva

Prevention of preterm birth in singleton pregnancies

17-alltlamino-17-demethoxygeldanamycin (17-AGG)

Treatment of multiple myeloma.

17-allylamino-17-demethoxygeldanamycin (17-AGG)

For the treatment of chronic myelogenous leukemia

1-Deoxygalactonojirimycin

Treatment of Fabry Disease

1-dexynojirimycin hydrochloride

Treatment of Pompe disease

2-(3,5-dichloro-phenyl)-benzoxazole-6carboxylic acid

Treatment of familial amyloid polyneuropathy

2-(3-diethylaminopropyl)-8,8-dipropyl-2azaspiro [4,5] decan dimaleate

Atiprimod

Treatment of mulitple myeloma and associated bone resorption

2-(3-Diethylaminopropyl)-8,8-dipropyl-2azaspiro[4,5] decane dimaleate

Atiprimod

Treatment of carcinoid tumors

2',3',5'-tri-o-acetyluridine

Treatment of mitochondrial disease

2-0-Butyryl-1-0-octyl-myo-inositol 3,4,5,6tetrakisphosphate

Treatment of cystic fibrosis

2-0-desulfated heparin

Aeropin

Treatment of cystic fibrosis.

20-mer complementary to Akt mRNA

Treatment of stomach cancer

20-mer oligonucleotide complementary to Akt mRNA

Treatment of pancreatic cancer

20-mer oligonucleotide complementary to Akt mRNA

Treatment of glioblastoma

20-mer oligonucleotide complementary to Akt mRNA

Treatment of renal cell carcinoma

20-mer oligonucleotide complementary to Akt mRNA

Treatment of ovarian cancer

2'-3'-dideoxyadenosine

Treatment of aquired immunodeficiency syndrome.

24,25 dihydroxycholecalciferol

Treatment of uremic osteodystrophy.

2-chloroethyl-3-sarcosinamide-1-nitrosourea

Treatment for malignant gliomas

2-chloroethyl-3-sarcosinamide-1-nitrosourea

Sarmustine

Treatment for malignant glioma As a host-protective agent in the treatment of acute myelogenous leukemia.

2'-deoxycytidine

2-methoxyestradiol

PulmoLAR

Treatment of pulmonary arterial hypertension

2-methoxyestradiol

Panzem NCD

Treatment of ovarian cancer

2-methoxyestradiol

Panzem

Treatment of multiforme glioblastoma

2-methoxyestradiol

Panzem

Treatment of multiple myeloma

2'-O-methyl-phosphorothiolate oliogribonucleotide

Treatment of Duchenne muscular dystrophy

3-(3,5-Dimethyl-1H-2ylmethylene)-1,3dihydro-indol-2-one

Treatment of von Hippel-Lindau disease.

3-(3,5-dimethyl-1H-2ylmethylene)-1,3-dihydroindol-2-one

Treatment of Kaposi's sarcoma.

3,4-diaminopyridine

Treatment of Lambert-Eaton myasthenic syndrome. Treatment of well-differentiated papillary, follicular or combined papillary/follicular carcinomas of the thyroid gland.

3,5,3'-triiodothyroacetate

3'-azido-2',3'dideoxyuridine

AZDU

Treatment of acquired immunodeficiency syndrome.

4-(2-fluorophenyl)-6-methyl-2-(1-piperzinyl)

Treatment of Chronic Functional Vomiting to include functional vomiting and cyclic vomiting syndrome.

4-(3-Methanesulfonyl-phenyl)-1propylpiperidine HCl

Treatment of Huntington disease.

4,5-dibromorhodamine 123

40SD02

Theralux Irradiation Deviceof chronic myelogenous leukemia Treatment Treatment of chronic iron overload resulting from conventional transfusional treatment of betathalassemia major and sickle cell anemia.

4-Amino-1-[5-O-[(2R, 4S)-2-oxido-4-(4pyridinyl)-1, 3, 2-dioxaphosphorinan-2-yl]-b-Darabinofuranosyl]-2(1H)-pyrimidinone

Treatment of hepatocellular carcinoma.

4-Aminopyridine

Treatment chronic functional motor and sensory deficits from Guillain-Barre syndrome Treatment of acute flares in pediatric patients with

4-aminosalicylic acid

Paser Granules ileo-cecal Crohn's disease

4-aminosalicylic acid

Pamisyl (P-D), Rezipas patients (Squibb) intolerant to sulfasalazine.

Treatment of mild to moderate ulcerative colitis in

4-cholest-en-3-one, oxime 4-cyano-N-[2-(1-cyclohexen-1-yl)-4-[1[dimethylamino)acetyl]-4-piperidinyl]phenyl]1H-imidazole-2-carboxamide monohydrochloride 4-trifluoromethyl-N-(3.3a.4.4a.5,5a,6,6aoctahydro-1,3-dioxo4,6ethenocycloprop[f]isoindol-2(1H)-yl)benzamide 4-trifluoromethyl-N-(3.3a.4.4a.5,5a,6,6aoctahydro-1,3-dioxo4,6ethenocycloprop[f]isoindol-2(1H)-yl)benzamide

Treatment of amyotrophic lateral sclerosis

5(S)-(2'-hydroxy ethoxy)-20(S)-Camptothecin

Treatment of osteosarcoma (bone cancer)

5,12-Naphthacenedione, 10-[[3-amino-2,3,6trideoxy-4-O-(phenylmethyl)-a-L-lyxohexopyranosyl]oxy]-7,8,9,10-tetrahydro6,8,11-trihydroxy-8-(hydroxyacetyl)-1methoxy-, hydrochloride, (8S,10S)- (9CI) 5,5',5"-[Phosphinothioylidyne-tris(imino-2,1ethanediyl)]tris[5methylchelidoninium]trihydroide hexahydrochloride

Treatment of malignant gliomas

5,6-dihydro-5-azacytidine

Treatment of malignant mesothelioma.

5,7-dihydroxy-3-(4-hydroxyphenyl)-chromen4-one

Prevention of acute radiation syndrome

506U78

Treatment of chronic lymphocytic leukemia.

5a8, monoclonal antibody to CD4

For use in post-exposure prophylaxis for occupational exposure to human immunodeficiency virus.

5-aza-2'-deoxycytidine

Treatment of acute leukemia.

5-hydroxymethyl-2-furfuraldehyde

Treatment of sickle cell disease

5-iodo-2-pytimidinone-2'-deoxyribose

Treatment of malginant glioma

5-methyl-1-phenyl-2-(1H)-pyridone(CAS 53179-13-8)

6,8-bis-benzylsulfanyl-octanoic acid

Treatment of acute myeloid leukemia

Treatment of smallpox.

post exposure prophylaxis against smallpox

Treatment of pancreatic cancer

Pirfenidone

Treatment of idiopathic pulmonary fibrosis

Treatment of pancreatic cancer

6-hydroxymethylacylfulvene

Treatment of histologically confirmed advanced or metastatic pancreatic cancer.

8 Cyclopentyl 1,3-dipropylxanthine

Treatment of cystic fibrosis.

8-methoxsalen

Uvadex

For use in conjunction with the UVAR photopheresis to treat diffuse systemic sclerosis.

8-methoxsalen

Uvadex

For the prevention of acute rejection of cardiac allografts.

90Y-hPAMA4

PAN-Cide

Treatment of pancreatic cancer

9-cis-retinoic acid

Prevention of retinal detachment due to proliferative vitreoretinopathy.

9-nitro-20-(S)-camptothecin

Treatment of pancreatic cancer.

9-nitro-20-(S)-camptothecin

Camvirex

Treatment of pediatric HIV infection/AIDS

a-(3-aminophthalimido) glutaramide

Actimid

Treatment of multiple myeloma

A10 & AS2-1 Antineoplaston

Treatment for patients with brain stem glioma

Abetimus

Treatment of lupus nephritis.

ACA125

Treatment of epithelial ovarian cancer Intravenous treatment of patients presenting with

Acetylcysteine

Mucomyst/Mucomyst 10 IV moderate to severe acetaminophen overdose.

acetylcysteine

Acetadote

For the intravenous treatment of moderate to severe acetaminophen overdose

Acid sphingomyelinase

Treatment of Niemann-Pick disease type B.

Aconiazide

Treatment of tuberculosis.

Adalimumab

Humira

Treatment of pediatric Crohn's disease.

Adalimumab

Humira

Treatment of juvenile rheumatoid arthritis

Adeno-associated vector expressing the human lipoprotein lipase protein Adeno-associated viral vector containing the gene for human coagulation factor IX

Treatment of lipoprotein lipase deficiency

Coagulin-B

Intramuscular treatment of patients with moderate to severe hemophilia

Adeno-associated viral vector containing the gene for human coagulation factor IX

Coagulin-B

Intrahepatic treatment of patients with moderate to severe hemophilia

Adeno-associated viral vector expressing human acid alpha glucosidase gene

Treatment for Pompe disease

adeno-associated viral vector expressing human retinoschisin-1 gene

Treatment of X-linked juvenile retinoschisis (XLRS).

Adeno-associated viral-based vector cystic fibrosis gene therapy

Treatment of cystic fibrosis.

Adenosine

For use in conjunction with BCNU in the treatment of brain tumors.

Adenoviral vector expressing Herpes simplex virus thymidine kinase gene

Treatment of malignant brain tumors

Adenovirus-based vector Factor VIII complementary DNA to somatic cells

MiniAdFVIII

Treatment of hemophilia A.

adenovirus-mediated herpes simplex virusthymidine kinase gene

Use with gancyclovir in the treatment of malignant glioma

Aerosolized pooled immune globulin

Treatment of respiratory syncytial virus lower respiratory tract disease.

a-Galactosidase A

Plant-Produced Human a-Glactosidase A Treatment of Fabry's disease

Aglycosyl anti-CD3 monoclonal antibody

Treatment of new-onset type I diabetes mellitus

AI-RSA

Albenza

Treatment of autoimmune uveitis. Treatment of neurocysticercosis due to Taenia solium as: 1) chemotherapy of parenchymal, subarachnoidal and racemose (cysts in spinal fluid) neurocysticercosis in symptomatic cases and 2) prophylaxis of epilepsy and other sequelae in asymptomatic neurocys

Albenza

Treatment of hydatid disease (cystic echinococcosis due to E. granulosus larvae or alveolar echinococcosis due to E. multilocularis larvae).

Albendazole

Albendazole

Albuterol

Prevention of paralysis due to spinal cord injury

Aldesleukin

Proleukin

Treatment of primary immunodeficiency disease associated with T-cell defects.

Aldesleukin

Proleukin

Treatment of metastatic renal cell carcinoma.

Aldesleukin

Proleukin

Treatment of metastatic melanoma.

Aldesleukin

Proleukin

For the treatment non-Hodgkin's lymphoma.

alemtuzumab

Campath

Treatment of chronic lymphocytic leukemia.

alendronate

Fosamax

Treatment of osteogenesis imperfecta in pediatric patients 4 years of age and older

Alendronate disodium

Fosamax

Treatment of the bone manifestations of Gaucher disease

Alfentanil

Management of postherpetic neuralgia

Alfentanil

Treatment of painful HIV-associated neuropathy

Alglucerase injection

Ceredase

Replacement therapy in patients with Type II and III Gaucher's disease.

Alglucerase injection

Ceredase

For replacement therapy in patients with Gaucher's disease type I.

Alitretinoin

Panretin

Topical treatment of cutaneous lesions in patients with AIDS-related Kaposi's sarcoma.

Alitretinoin

Panretin

Treatment of acute promyelocytic leukemia

allantoin

Alwextin

Treatment of skin blistering and erosions associated with inherited epidermolysis bullosa

Allogeneic human retinal pigment epithelial cells on gelatin microcarriers

Spheramine

Treatment of Hoehn and Yahr stage 3 and 4 Parkinson's disease.

Allogeneic peripheral blood mononuclear cells sensitized against patient alloantigens by CYTOIMPLANT Treatment of pancreatic cancer mixed lymphocyte culture Allogeneic retinal epithelial cells transfected with plasmid vector expressing ciliary neurotrophic growth factor Allogeneic T-cells cultured with anti-CD3 and IL-2; transduced with retroviral vector (SFCMM-3), expressing herpes simplex 1 virus-thymidine kinase (HSV-TK) and truncated low affinity nerve growth factor receptor; selected with anti-low affinity nerve gro

Allopurinol riboside

Allopurinol riboside

Allopurinol sodium

Treatment of retinitis pigmentosa

Immunotherapy for acceleration of T-cell reconstitution in patients undergoing allogeneic hematopoietic stem cell transplantation

Treatment of cutaneous and visceral leishmaniasis.

Treatment of Chagas' disease. Management of patients with leukemia, lymphoma, and solid tumor malignancies who are receiving cancer therapy which causes elevations of serum and urinary uric acid levels and who cannot tolerate oral Aloprim for Injection therapy.

Allopurinol sodium

Ex-vivo preservation of cadaveric kidneys for transplantation

Alpha-1-acid glycoprotein

Treatment of cocaine overdose

Alpha-1-acid glycoprotein

Treatment of tricyclic antidepressant poisoning

Alpha-1-antitrypsin (recombinant DNA Origin)

As supplementation therapy for alpha-1-antitrypsin deficiency in the ZZ phenotype population.

Alpha1-Proteinase Inhibitor (Human)

Inhalation therapy for the the treatment of congential deficiency of alpha1-proteinase inhibitor.

Alpha1-Proteinase Inhibitor (Human)

ARC-API

Treatment of cystic fibrosis For slowing the progression of emphysema in alpha1antitrypsin deficient patients.

Alpha1-proteinase inhibitor (human)

Alpha1-proteinase inhibitor (human)

Prolastin

For replacement therapy in the alpha-1-proteinase inhibitor congenital deficiency state.

Alpha-galactosidase A

Fabrase

Treatment of Fabry's disease.

Alpha-galactosidase A

CC-galactosidase (Fabry's disease).

Alpha-galactosidase A

Replagal

Treatment of alpha-galactosidase A deficiency Long-term enzyme replacement therapy for the treatment of Fabry disease.

Alpha-melanocyte stimulating hormone

Prevention and treatment of intrinsic acute renal failure due to ischemia.

Alpha-tocopherol quinone

Treatment of inherited mitochondrial respiratory chain diseases

Alprostadil

Treatment of severe peripheral arterial occlusive disease (critical limb ischemia) in patients where other procedures, grafts or angioplasty, are not indicated.

alteplase

Activase

Treatment of intraventricular hemmorage associated with intracerebral hemmorrhage

Altretamine

Hexalen

Treatment of advanced adenocarcinoma of the ovary. Teatment of B-cell chronic lymphocytic leukemia (BCLL) or prolymphocytic leukemia arising from CLL.

Alvocidib

ambrisentan

Letairis

AMG 531

Treatment of pulmonary arterial hypertension

Treatment of immune thrombocytopenic purpura.

Amifostine

Ethyol

Treatment of myelodysplastic syndromes.

Amifostine

Ethyol

For use as a chemoprotective agent for cisplatin in the treatment melanoma. For use asofa metastatic chemoprotective agent for

Amifostine

Ethyol

cyclophosphamide in the treatment of advanced ovarian carcinoma.

Amifostine

Ethyol

For use as a chemoprotective agent for cisplatin in the treatment of advanced ovarian carcinoma.

Amifostine

Ethyol

Reduction of the incidence of moderate to severe xerostomia in patients undergoing post-operative radiation treatment for head and neck cancer.

Amifostine

Ethyol

For the reduction of the incidence and severity of toxicities associated with cisplatin administration.

Amikacin

SLIT Amikacin aeruginosa infections in cystic fibrosis patients

Treatment of bronchopulmonary Pseudomonas

Amiloride HCl solution for inhalation

Treatment of cystic fibrosis.

Aminocaproic acid

Caprogel

For the topical treatment of traumatic hyphema of the eye.

Aminolevlinic acid hydrochloride

Levulan

Treatment of esophageal dysplasia

Aminosalicylate sodium

Treatment of Crohn's disease.

Aminosalicylic acid

Paser Granules Treatment of tuberculosis infections

Aminosidine

Paromomycin

Treatment of visceral leishmaniasis

Aminosidine

Paromomycin

Treatment of visceral leishmaniasis (kala-azar).

Aminosidine

Gabbromicina

Treatment of tuberculosis.

Aminosidine

Gabbromicina

Treatment of Mycobacterium avium complex.

Amiodarone

Amio-Aqueous Treatment of incessant ventricular tachycardia.

Amiodarone HCl

Cordarone

For the acute treatment and prophylaxis of lifethreatening ventricular tachycardia or ventricular fibrillation.

Ammonium tetrathiomolybdate

Coprexa

Treatment of Wilson's disease.

amonafide L-malate

Xanafide

Treatment of acute myeloid leukemia. Prevention of pulmonary fungal infections in patients at risk for aspergillosis due to immunosuppressive therapy including those receiving organ or stem cell transplants, or teated with chemotherapy or radiation for hematologic malignancies

Amphotericin B lipid complex

Abelcet

Treatment of invasive protothecosis.

Amphotericin B lipid complex

Abelcet

Treatment of invasive sporotrichosis.

Amphotericin B inhalation powder

Amphotericin B lipid complex

Abelcet

Treatment of invasive coccidioidomycosis.

Amphotericin B lipid complex

Abelcet

Treatment of invasive zygomycosis.

Amphotericin B lipid complex

Abelcet

Treatment of invasive candidiasis.

Amphotericin B lipid complex

Abelcet

Treatment of invasive fungal infections.

Amsacrine

Amsidyl

Treatment of acute adult leukemia.

Kit Amyl nitrite, sodium nitrite, sodium thiosulfate Cyanide AntidoteTreatment of cyanide poisoning

Anagrelide

Agrylin

Treatment of thrombocytosis in chronic myelogenous leukemia.

Anagrelide

Agrylin

Treatment of essential thrombocythemia.

Anagrelide

Agrylin

Treatment of polycythemia vera.

Ananain, comosain

Vianain

For the enzymatic debridement of severe burns.

Anaritide acetate

Auriculin

Treatment of patients with acute renal failure.

Anaritide acetate

Auriculin

Anatibant Ancrod

Viprinex

Angiotensin 1-7

MARstem

Angiotensin 1-7

Improvement of early renal allograft function following renal transplantation. Treatment of patients having experienced a severe traumatic brain injury (Glasgow Coma Scale 3 to 8) in order to decrease early mortality and improve longTo establish and maintain anticoagulation in heparinterm functional andundergoing neurological outcome intolerant patients cardiopulmonary bypass.

Treatment of myelodysplastic syndrome Treatment of neutropenia associated with autologous bone marrow transplantation. For ex-vivo treatment to eliminate mature T cells from

Anti pan T lymphocyte monoclonal antibody

Anti-t Lymphocyte Immunotoxin Xmmly-h65-rta potential bone marrow grafts.

Anti pan T lymphocyte monoclonal antibody

Anti-t Lymphocyte Immunotoxin Xmmly-h65-rta prevent graft rejection and graft versus host disease.

antiangiogenic components extracted from marine cartilage

Neovastat (AE-941) Treatment of renal cell carcinoma

For in-vivo treatment of bone marrow recipients to

anti-CD23 IgG1, kappa monoclonal antibody

Treatment of chronic lymphocytic leukemia

Anti-CD40 mAb

Treatment of chronic lymphocytic leukemia

Anti-CD45 monoclonal antibodies

Prevention of acute graft rejection of human organ transplants.

Anti-CEA Sheep-human chimeric monoclonal antibody labeled w/iodine-131 (KAb201)

Treatment of pancreatic cancer

Anti-cytomegalovirus monoclonal antibodies

Prevention of human cytomegalovirus infection in bone marrow and organ transplant patients.

Anti-cytomegalovirus monoclonal antibodies

Treatment of human cytomegalovirus infection in bone marrow and organ transplant patients.

Anti-cytomegalovirus monoclonal antibodies

Prevention of human cytomegalovirus infection in patients diagnosed with AIDS.

Anti-cytomegalovirus monoclonal antibodies

Treatment of human cytomegalovirus infection in patients diagnosed with AIDS.

Anti-cytotoxic T lymphocyte antigen 4 monoclonal antibody

Treatment of stage IIb to stage IV metastatic melanoma

Antiepilepsirine

Treatment of drug resistant generalized tonic-clonic epilepsy in children and adults.

Antihemophilic factor (human)

Alphanate

Antihemophilic factor (recombinant)

ReFacto

Treatment of von Willebrand's disease For the control and prevention of hemorrhagic episodes and for surgical prophylaxis in patients with hemophilia A (congenital factor VIII deficiency or classic hemophilia).

Antihemophilic factor (recombinant)

Kogenate

Prophylaxis and treatment of bleeding in individuals with hemophilia A or for prophylaxis when surgery is required in individuals with hemophilia A.

Antihemophilic factor/von Willebrand factor complex (human), dried, pasteurized

Humate-P

Treatment of patients with von Willebrand's disease

For the treatment of immunologic corneal allograft rejection

anti-interferon-gamma Fab from goats Antimelanoma Antibody XMMME-001-DTPA 111 Indium

Antimelanoma Antibody XMMME-001-DTPA 111 Indium melanoma metastasis.

Diagnostic use in imaging systemic and nodal

Antimelanoma Antibody XMMME-001-RTA

Antimelanoma Antibody XMMME-001-RTA surgical resection.

Treatment of stage III melanoma not amenable to

Antipyrine Test

For use as an index of hepatic drug-metabolizing capacity.

Antisense 20-mer oligonucleotide complementary to R2 component of ribonucleotide reductase mRNA

Treatment of acute myeloid leukemia

antisense 20-mer phosphorothioate oligonucleotide [complementary to the coding region of R2 component of the human GTI-2040 ribonucleotide reductase mRNA]

Treatment for renal cell carcinoma

Antisense inhibitor of apoB-100

Treatment of homozygous familial hypercholesterolemia

Anti-tap-72 immunotoxin

Xomazyme-791 Treatment of metastatic colorectal adenocarcinoma.

Anti-tenascin 81C6 monoclonal antibody labeled w/ I 131

Antithrombin III (human)

ATnativ

Antithrombin III (human)

Thrombate III

Antithrombin III (human) concentrate IV

Kybernin P

Antithrombin III human

Treatment of primary malignant brain tumors For the treatment of patients with hereditary antithrombin III deficiency in connection with surgical or obstetrical procedures or when they suffer from thromboembolism. For replacement therapy in congenital deficiency of

AT-III for prevention and treatment of thrombosis and pulmonary emboli.

For prophylaxis and treatment of thromboembolic episodes in patients with genetic AT-III deficiency. Preventing or arresting episodes of thrombosis in patients with congenital AT-III deficiency and/or to prevent the occurrence of thrombosis in patients with AT-III deficiency who have undergone trauma or who Antithrombin III human are about to undergo surgery or parturition.

Anti-thymocyte Globulin (Rabbitt)

Thymoglobulin Treatment of myelodysplastic syndrome (MDS) Treatment of allograft rejection, including solid organ

Anti-thymocyte serum

Nashville Rabbit marrow Anti-thymocyte Serum transplantation.

Antivenin crotaline (pit-viper) equine immune F(ab)2)

Antivipmyn

Treatment of envenomation by Crotaline snakes

Antivenin, crotalidae polyvalent immune Fab (ovine)

CroFab

Treatment of envenomations inflicted by North American crotalid snakes.

(kidney, liver, heart, lung, and pancreas) and bone

Antivenom (crotalidae) purified (avian)

Treatment of envenomation by poisonous snakes belonging to the Crotalidae family.

AP1903

Treatment of acute graft-versus-host disease in patients undergoing bone marrow transplantation.

APL 400-020 V-Beta DNA vaccine

Treatment of cutaneous T cell lymphoma.

Apomorphine

For use as rescue treatment for early morning motor dysfunction in late-stage Parkinson's disease.

Apomorphine

Treatment of the on-off fluctuations associated with late-stage Parkinson's disease.

Apomorphine hydrochloride

Treatment of the on-off fluctuations associated with late-stage Parkinson's disease. For the treatment of patients in a vegetative state or minimally conscious state for up to 12 months following a severe traumatic brain injury (traumatic or spontaneous)

Aprotinin

Trasylol

For prophylactic use to reduce perioperative blood loss and the homologous blood transfusion requirement in patients undergoing cardiopulmonary bypass surgery in the course of repeat coronary artery bypass graft surgery, and in selected cases of primary c

Arcitumomab

99m Tc-labeled CEA-Scan recurrent and metastatic medullary thyroid carcinoma.

Apomorphine HCl

Arginine butyrate

Apokyn

Diagnosis and localization of primary, residual,

Treatment of sickle cell disease and beta thalassemia.

Arginine butyrate

Treatment of beta-hemoglobinopathies and betathalassemia.

arimoclomol

Treatment of amyotrophic lateral sclerosis

Aripiprazole

Abilify

Treatment of Tourette's syndrome

arsenic

Trisenox

Treatment of acute myelocytic leukemia subtypes M0, M1, M2, M4, M5, M6 and M7

Arsenic trioxide

Trisenox

Treatment of malignant glioma

arsenic trioxide

Trisenox

Treatment of chronic myeloid leukemia

Arsenic trioxide

Trisenox

Treatment of acute promyelocytic leukemia.

Arsenic trioxide

Trisenox

Treatment of multiple myeloma.

arsenic trioxide

Trisenox

Treatment of liver cancer

Arsenic trioxide

Trisenox

Treatment of chronic lymphocytic leukemia

arsenic trioxide

Trisenox

Treatment of myelodysplastic syndrome.

artemether/lumefantrine

Coartem

For the treatment of infections due to Plasmodium falciparum or mixed infections including P. falciparum.

Artesunate

Immediate treatment of malaria

Artesunate

Treatment of malaria.

As-101

Treatment of acquired immunodeficiency syndrome.

Ascorbic acid

Ascor L 500

Treatment of scurvy

Atomoxetine hydrochloride

STRATTERA

Atovaquone

Mepron

Treatment of Tourette's Syndrome Prevention of Pneumocystis carinii pneumonia (PCP) in high-risk, HIV-infected patients defined by a history of one or more episodes of PCP and/or a peripheral CD4+ (T4 helper/inducer) lymphocyte count less than or equal to 200/mm3.

Atovaquone

Mepron

Treatment of AIDS associated Pneumocystis Carinii Pneumonia.

Atovaquone

Mepron

Primary prophylaxis of HIV-infected persons at high risk for developing Toxoplasma gondii encephalitis.

Atovaquone

Mepron

Treatment and suppression of Toxoplasma gondii encephalitis.

Attenuated autologous cancer cells and granulocyte macrophage colony stimulating factor in combination with activated autologous blood derived T-cells

Treatment of primary central nervous system malignancies

augmerosen

Genasense

Treatment of acute myelocytic leukemia

augmerosen

Genasense

Treatment of multiple myeloma

augmerosen

Genasense

Treatment of chronic lymphocytic leukemia

autologous antigen presenting cells pulsed with autologous tumor Ig idiotype

Mylovenge

Treatment of multiple myeloma

Autologous cultured endothelial cells on a donor human corneal disk

Treatment of Fuch's dystrophy, pseudophakic bullous keratopathy, and bullous keratopathy

Autologous dendritic cells pulsed with autologous antigens from primay malignant brain tumor cells

DCVax-Brain

Autologous DNP-conjugated tumor vaccine

M-Vax

Autologous macrophage Autologous incubated or allogeneic limbal epithelial stem cells expanded ex vivo on human amniotic membrane

Treatment of therapy primary in brain malignant cancerwith For adjuvant melanoma patients surgically resectable lymph node metastasis (Stage III and limited Stage IV disease). Therapy to improve the motor and sensory neurological outcome in acute cases of spinal cord injury Treatment of ocular surface diseases that are characterized by total limbal stem cell deficiency

autologous tumor-derived gp96 heat shock protein-peptide complex

Oncophage

Treatment of renal cell carcinoma

autologous tumor-derived gp96 heat shock protein-peptide complex

Oncophage

Treatment of metastatic melanoma

Autolymphocyte therapy

Treatment of renal cell carcinoma.

axitinib

For treatment of pancreatic cancer.

azacitidine

Vidaza

Azathioprine

Imuran

Treatament of myelodysplastic syndromes

aztreonam

Treatment of oral manifestations of graft-versus-host disease. Inhalation therapy for control of gram-negative bacteria in the respiratory tract of patients with cystic fibrosis

Bacillus Calmette-Guerin vaccine

Treatment of stage IIb through IV metastatic melanoma

Bacitracin

Baclofen

Treatment of antibiotic-associated pseudomembranous enterocolitis caused by toxins A Altracin and B elaborated by Clostridium difficile. Treatment of intractable spasticity caused by spinal cord injury, multiple sclerosis, and other spinal diseases (including spinal ischemia, spinal tumor, transverse myelitis, cervical spondylosis, and Lioresal Intrathecal degenerative myelopathy). Treatment of intractable spasticity due to multiple sclerosis or spinal cord injury.

Baclofen

Baclofen

Lioresal Intrathecal Treatment of spasticity associated with cerebral palsy.

baclofen

Treatment of dystonia

Balsalazide disodium

Colazal

Basiliximab

Simulect

beclomethasone 17,21-dipropionate

Bec

Treatment of pediatric patients with ulcerative colitis Prophylaxis of solid organ rejection.

Prevention of gastrointestinal graft-versus-host disease For oral administration in the treatment of intestinal graft-versus-host disease.

Beclomethasone dipropionate

Bendamustine hydrochloride

Treanda

Benzoate and phenylacetate

Ucephan

Treatment of chronic lymphocytic leukemia For adjunctive therapy in the prevention and treatment of hyperammonemia in patients with urea cycle enzymopathy due to carbamylphosphate synthetase, ornithine, transcarbamylase, or argininosuccinate synthetase deficiency.

benzoate/phenylacetate

Ammonul

Benzophenone-3, octylmethoxycinnamate, avobenzone, titanium dioxide, zinc oxide

Treatment of acute hyperammonemia and associated encephalopathy in patients with deficiencies in enzymes of the urea For the prevention of cycle. visible light induced skin

Total Block VL SPF 75 photodynamic therapy

Benzydamine hydrochloride

Tantum

photosensitivity as a result of porfimer sodium

Beractant

Prophylactic treatment of oral mucositis resulting from radiation therapy for head and neck cancer. Assessing the risk of administrating penicillin when it is the preferred drug of choice in adult patients who have previously received penicillin and have a history Pre-Pen/MDM of clinical sensitivity. Treatment of full-term newborn infants with respiratory failure caused by meconium aspiration syndrome, persistent pulmonary hypertension of the newborn, or Survanta Intratracheal Suspension pneumonia and sepsis.

Beractant

Survanta intratracheal suspension Prevention of neonatal respiratory distress syndrome.

Beractant

Survanta intratracheal suspension Treatment respiratory distress syndrome. Treatment of of neonatal pulmonary arterial hypertension

Benzylpenicillin, benzylpenicilloic, benzylpenilloic acid

associated with any New York Heart Association classification (Class I, II, III, or IV).

Beraprost

Beta alethine

Betathine

Treatment of metastatic melanoma.

Beta alethine

Betathine

Treatment of multiple myeloma.

Betaine

Cystadane

Treatment of homocystinuria.

Bethanidine sulfate

Prevention of recurrence of primary ventricular fibrillation.

Bethanidine sulfate

Treatment of primary ventricular fibrillation.

Betulinic acid

Topical treatment of metastatic melanoma

Bevacizamub

Avastin

Treatment of malignant glioma

Bevacizumab

Avastin

Therapeutic treatment of patients with ovarian cancer

Bevacizumab

Avastin

Treatment of pancreatic cancer

Bevacizumab

Avastin

Treatment of renal cell carcinoma

Targretin

Treatment of cutaneous manifestations of cutaneous T-cell lymphoma in patients who are refractory to at least one prior systemic therapy.

Bexarotene

bifidobacterium longum infantis 35624

Treatment of pediatric Crohn's disease

Bindarit

Treatment of lupus nephritis.

Bioartificial liver system utilizing xenogenic hepatocytes in a hollow fiber bioreactor cartridge (BAL)

Treatment of patients with acute liver failure presenting with encephalopathy deteriorating beyond Parson's grade 2

biocarbonate infusate

Bio-engineered oral mucosal tissue

Use in the management of patients undergoing continuous renal replacement therapy with Normocarb HF hemofiltration For use as a graft for restoring a cornea-like epithelial phenotype to substitute for the normal corneal epithelium that is lost in patients due to total limbal stem cell deficiency

Bis(4-fluorophenyl)phenylacetamide Bispecific molucule with two linked murine single-chain Fv regions directed against CD3 & CD19

Treatment of sickle cell disease. Treatment of indolent B-cell lymphoma, excluding CLL and NHL with CNS involvement

bivalirudin

Angiomax

For use as an anticoagulant in patients with or at risk of heparin-induced thrombocytopenia/heparin-induced thrombocytopenia thrombosis syndrome

Bleomycin

Blenoxane

Treatment of pancreatic cancer.

Bleomycin sulfate

Blenoxane

BMY-45622

Treatment of malignant pleural effusion.

Treatment of ovarian cancer.

Bortezomib

Velcade

Treatment of multiple myeloma

Bosentan

Tracleer

Treatment of pulmonary arterial hypertension.

Botulinum toxin type A

Dysport

Treatment of dynamic muscle contractures in pediatric cerebral palsy patients.

Botulinum toxin type A

Dysport

Treatment of spasmodic torticollis (cervical dystonia).

Botulinum toxin type A

Dysport

Treatment of essential blepharospasm.

Botulinum toxin type A

Botox

Botulinum toxin type A

Treatment of dynamic muscle contracture in pediatric cerebral palsy patients. Treatment of synkinetic closure of the eyelid associated with VII cranial nerve aberrant regeneration.

Botulinum toxin type A

Botox

Treatment of cervical dystonia.

Botulinum toxin type A

Botox

Treatment of strabismus associated with dystonia in adults (patients 12 years of age and above).

Botulinum toxin type A

Botox

Treatment of blepharospasm associated with dystonia in adults (patients 12 years of age and above).

Botulinum toxin type B

Myobloc

Treatment of cervical dystonia.

Botulinum toxin type F

Treatment of spasmodic torticollis (cervical dystonia).

Botulinum toxin type F

Treatment of essential blepharospasm.

Botulism immune globulin

BabyBIG

Bovine colostrum

Treatment of AIDS-related diarrhea.

Bovine immunoglobulin concentrate, Cryptosporidium parvum

Sporidin-G

Bovine whey protein concentrate

Immuno-C

Branched chain amino acids

Brimonidine

Treatment of infant botulism.

Treatment and symptomatic relief of Cryptosporidium parvum infection of the gastrointestinal tract in Treatment of cryptosporidiosis immunocompromised patients. caused by the presence of Cryptosporidium parvum in the gastrointestinal tract of patients who are immunodeficient/immunocompromised or immunocompetent.

Treatment of amyotrophic lateral sclerosis.

Alphagan

Treatment of anterior ischemic optic neuropathy.

Brivaracetam

Treatment of symtomatic myoclonus Treatment of mild to moderate keratoconjunctivitis sicca in patients with Sjogren's syndrome.

Bromhexine

Bisolvon

Broxuridine

Broxine/Neomarktumors.

Radiation sensitizer in the treatment of primary brain

Buffered intrathecal electrolyte/dextrose injection

For use in combination with paclitaxel in the treatment of esophageal cancer For use as a diluent in the intrathecal administration of methotrexate and cytarabine for the prevention or treatment meningeal leukemia and lymphocytic Elliotts B Solutionlymphoma.

Buffered Ursodeoxycholic Acid

Ursocarb

For the treatment of pruritus in patients with Alagille Syndrome

Buprenorphine hydrochloride

Subutex

Treatment of opiate addiction in opiate users.

Buprenorphine in combination with naloxone

Suboxone

Treatment of opiate addiction in opiate users.

Busulfan

Busulfex

As preparative therapy in the treatment of malignancies with bone marrow transplantation.

Busulfan

Spartaject

For use as preparative therapy for malignancies treated with bone marrow transplantation.

Busulfan

Spartajet-Busulfan Intrathecal therapy for neoplastic meningitis

busulfan

Partaject

Busulfan

Spartaject

bryostatin-1

Preparative therapy for pediatric patients undergoing bone marrow transplantation

Buthionine sulfoxamine

Treatment of primary malignancies. For use in children asbrain a modulator of chemotherapy for the treatment of pediatric patients with neuroblastoma Use as a modulator of chemotherapy for the treatment of pediatric patients with primary malignant brain tumors

Butyrylcholinesterase

Treatment of post-surgical apnea.

Butyrylcholinesterase

For the reduction and clearance of toxic blood levels of cocaine encountered during a drug overdose.

BW 12C

Treatment of sickle cell disease.

C1 esterase inhibitor (human)

Treatment of angioedema

C1 esterase inhibitor (human)

Treatment and prevention of angioedema caused by C1-esterase inhibitor deficiency.

Buthionine sulfoxamine

Prevention and/or treatment of acute attacks of hereditary Preventionangioedema. of acute attacks of angioedema, including

C1-esterase-inhibitor, human, pasteurized

Berinert P

C1-inhibitor

C1-inhibitor (human) heated, Immuno othervapor surgical procedures.

short-term prophylaxis for patients requiring dental or

C1-inhibitor

C1-inhibitor (human) vaporofheated, Immuno Treatment acute attacks of angioedema.

cAC10-vcMMAE (4)

Treatment of Hodgkin's lymphoma.

Caffeine

Cafcit

Calcitonin salmon nasal spray

Miacalcin Nasal Spray deformans).

Calcitonin-human for injection

Cibacalcin

Treatment of symptomatic Paget's disease (osteitis deformans).

Calcium acetate

Phos-Lo

Treatment of hyperphosphatemia in end stage renal failure.

Treatment of apnea of prematurity. Treatment of symptomatic Paget's disease (osteitis

Treatment of hyperphosphatemia in end stage renal disease.

Calcium acetate

Treatment of hyperphosphatemia in patients with end

Calcium carbonate

R & D calcium carbonate/600 stage renal disease.

Calcium gluconate

Calgonate

For use as a wash for hydrofluoric acid spills on human skin.

Calcium gluconate gel

H-F Gel

For use in the emergency topical treatment of hydrogen fluoride (hydrofluoric acid) burns. Emergency topical treatment of hydrogen fluoride (hydrofluoric acid) burns.

Calcium gluconate gel 2.5%

Calfactant

Infasurf

Capsaicin

Acute respiratory distress syndrome (ARDS)

Capsaicin

Treatment of postherpetic neuralgia. Treatment of intermetatarsal neuroma (Morton's Neuroma) that does not respond to conservative treatment and requires either neurectomy or neurolysis

capsaicin

Treatment of erythromelalgia

Capsaicin

Treatment of painful HIV-associated neuropathy

Carbamylglutamic acid

Treatment of N-acetylglutamate synthetase deficiency. Treatment of persons with AIDS and in patients with

Carbovir

symptomatic HIV infection and a CD4 count less than 200/mm3.

Carmustine

Treatment of intracranial malignancies.

Cascara sagrada fluid extract

Treatment of oral drug overdosage to speed lower bowel evacuation.

Catumaxomab

Removab

Treatment of ovarian cancer

CD4 human truncated 369 AA polypeptide CD5-T lymphocyte immunotoxin

Soluble T4

Treatment of acquired immunodeficiency syndrome. Treatment of graft versus host disease and/or rejection in patients who have received bone marrow Xomazyme-H65 transplants.

CDP571

Ceftriaxone sodium

Treatment of Crohn's disease.

Rocephin

Cells produced using the AastromReplicelle System and SC-I Therapy Kit

Treatment of amyotrophic lateral sclerosis For use in patients receiving high dose chemotherapy who are unable to generate an acceptable dose of peripheral blood stem cells and who have a sufficient bone marrow aspirate without morphological evidence of tumor

Cenersen sodium

Treatment of acute myeloid leukemia

Centruroides immune F(ab)2

Alacramyn

Treatment of scorpion envenomations requiring medical attention.

Ceramide trihexosidase/alpha-galactosidase A

Fabrazyme

Treatment of Fabry's disease.

cethromycin

Prophylactic treatment of patients exposed to inhalation anthrax.

Cetiedil citrate injection

Treatment of sickle cell disease crisis.

Erbitux

Treatment of pancreatic cancer

Cetuximab

Erbitux

Treatment of squamous cell cancer of the head and neck in patients who express epidermal growth factor receptor.

Chenodeoxycholic acid

Chenofalk

Treatment of cerebrotendinous xanthomatosis

Chenix

Treatment of cerebrotendinous xanthomatosis For patients with radiolucent stones in well opacifying gallbladders, in whom elective surgery would be undertaken except for the presence of increased surgical risk due to systemic disease or age.

cetuximab

chenodeoxycholic acid

Chenodiol Chimeric (human-murine) G250 IgG monoclonal antibody

Treatment of renal cell carcinoma.

chimeric (murine-human) IgG1 mAb against IL-6

Treatment of multiple myeloma

Chimeric (murine-human) IgG1k monoclonal antibody against interleukin-6

Treatment of Castleman's disease

Chimeric monoclonal antibodies

For treatment of shiga-toxin producing bacterial infection.

Chimeric monoclonal antibody to mesothelin

Treatment of pancreatic cancer

Chimeric M-T412 (human-murine) IgG monoclonal anti-CD4

Treatment of multiple sclerosis.

Chimeric, humanized monoclonal antibody to staphylococcus

Chlorhexidine gluconate mouthrinse

Peridex

Prophylaxis of Staphylococcus epidermidis sepsis in low birth weight (1500 grams or less) infants. For use in the amelioration of oral mucositis associated with cytoreductive therapy used in conditioning patients for bone marrow transplantation therapy.

cholic acid (3 alpha, 7 alpha, 12 alpha trihydroxy 5-beta cholanolic acid)

Falkochol

Treatment of inborn errors of cholesterol and bile acid synthesis and metabolism

Choline chloride

Intrachol

Treatment of choline deficiency, specifically the choline deficiency, hepatic steatosis, and cholestasis, associated with long-term parenteral nutrition.

Choline chloride

IntraChol

Prevention and/or treatment of choline deficiency in patients on long-term parenteral nutrition

Chondrocyte-alginate gel suspension

For use in correcting vesicoureteral reflux in the pediatric population.

Chondroitinase

Treatment of patients undergoing vitrectomy.

cilengitide

Treatment of malignant glioma

Ciliary neurotrophic factor Ciliary neurotrophic factor, recombinant human

Treatment of amyotrophic lateral sclerosis. Treatment of motor neuron disease (including amyotrophic lateral sclerosis, progressive muscular atrophy, progressive bulbar palsy, and primary lateral sclerosis).

Ciliary neurotrophic factor, recombinant human

Treatment of spinal muscular atrophies.

cinacalcet

Sensipar

cis-Amminedichloro(2methylpyridine)platinum(II)

Treatment of hypercalcemia in patients with parathyroid carcinoma

Treatment of small cell lung cancer. Treatment of osteogenic sarcoma metastatic to the

Cisplatin in liposomal formulation

SLIT Cisplatin forlung inhalation

Cisplatin/epinephrine

IntraDose

Treatment of metastatic malignant melanoma.

Cisplatin/epinephrine

IntraDose

Treatment of squamous cell carcinoma of the head and neck.

Citric acid, glucono-delta-lactone and magnesium carbonate

Renacidin Irrigation or struvite variety.

Civamide

Zucapsaicin

Treatment of renal and bladder calculi of the apatite

Treatment of postherpetic neuralgia of the trigeminal nerve

Cladribine

Leustatin

Cladribine

Leustatin Injection Treatment of hairy cell leukemia.

Cladribine

Leustatin Injection Treatment of chronic lymphocytic leukemia.

Cladribine

Mylinax

Cladribine

Leustatin Injection Treatment of non-Hodgkin's lymphoma.

Clazosentan

Erajet

Treatment of cerebral vasospasm following subarachnoid hemorrhage

Clindamycin

Cleocin

Prevention of Pneumocystis carinii pneumonia in AIDS patients.

Clindamycin

Cleocin

Treatment of Pneumocystis carinii pneumonia associated with AIDS patients.

Clindamycin hydrochloride

Treatment of acute myeloid leukemia.

Treatment of the chronic progressive form of multiple sclerosis.

Treatment of sarcoidosis

clofarabine

Clofarex

Treatment of acute myelogenous leukemia

clofarabine

Clolar

Treatment of acute lymphoblastic leukemia

Clofazimine

Lamprene

Treatment of lepromatous leprosy, including dapsoneresistant lepromatous leprosy and lepromatous leprosy complicated by erythema nodosum leprosum.

Clonazepam

Klonopin

Clonidine

Duraclon

Treatment of hyperekplexia (startle disease). For continous epidural administration as adjunctive therapy with intraspinal opiates for the treatment of pain in cancer patients tolerant to, or unresponsive to, intraspinal opiates.

Clostridial collagenase

Treatment of advanced (involutional or residual stage) Dupuytren's disease.

Clotrimazole

Topical treatment of children and adults with pouchitis

Clotrimazole

Treatment of Huntington's disease

Clotrimazole

Treatment of sickle cell disease.

c-myb antisense oligodeoxynucleotide

Treatment of chronic myelogenous leukemia

Coagulation factor IX

Mononine

Replacement treatment and prophylaxis of the hemorrhagic complications of hemophilia B.

Coagulation Factor IX (human)

AlphaNine

For use as replacement therapy in patients with hemophilia B for the prevention and control of bleeding episodes, and during surgery to correct defective hemostasis.

Coagulation Factor IX (recombinant)

BeneFix

Treatment of hemophilia B.

Coagulation factor VIIa (recombinant)

NovoSeven

Prevention of bleeding episodes in patients with acquired inhibitors to Factor VIII or Factor IX

Coagulation factor VIIa (recombinant)

NovoSeven

Coagulation factor VIIa (recombinant)

NovoSeven

Coagulation Factor VIIa (Recombinant)

NovoSeven

Treatment of bleeding episodes in patients with acquired inhibitors to Factor VIII or Factor IX

Coagulation factor VIIa (recombinant)

NovoSeven

Prevention of bleeding episodes in patients with hemophilia A or B, with or without inhibitors

Coagulation factor VIIa (Recombinant)

NovoSeven

Treatment of bleeding episodes in Glanzmann's thrombasthenia

Coagulation factor VIIa (recombinant)

NovoSeven

Treatment of bleeding episodes in patients with congenital factor VII deficiency

Coagulation Factor VIIa (Recombinant)

NovoSeven

Treatment of bleeding in patients experiencing intracranial hemorrhage.

Coagulation factor VIIa (recombinant)

NovoSeven

Treatment of bleeding episodes in hemophilia A or B patients with inhibitors to Factor VIII or Factor IX.

Prevention of bleeding episodes in Glanzmann's thrombasthenia Prevention of bleeding episodes in patients with congenital Factor VII deficiency

cobiprostone

Treatment of cystic fibrosis

Coenzyme Q10

Treatment of Huntington's disease

colchicine

Treatment of familial Mediterranean fever

colchicine

For the treatment of Behcet's Syndrome.

Colchicine

For arresting the progression of neurologic disability caused by chronic progressive multiple sclerosis. Treatment of established hyaline membrane disease

Colfosceril palmitate, cetyl alcohol, tyloxapol

Exosurf Neonatalat for Suspension all Intratracheal gestational ages. Prevention of hyaline membrane disease, also known

Colfosceril palmitate, cetyl alcohol, tyloxapol

Exosurf Neonatalweeks for Intratracheal Suspension gestation or less.

Colfosceril palmitate, cetyl alcohol, tyloxapol

Exosurf

Treatment of adult respiratory distress syndrome.

Collagenase (lyophilized) for injection

Plaquase

Treatment of Peyronie's disease.

Combretastatin A4 phosphate Combretastatin A4 Phosphate

as respiratory distress syndrome, in infants born at 32

Treatment of ovarian cancer Treatment of anaplastic thyroid cancer, medullary thyroid cancer, and stage IV papillary or follicular thyroid cancer

conjugate of human transferrin and a mutant diphtheria toxin (CRM 107)

TransMID

Treatment of malignant tumors of the central nervous system

conjugated bile acids

COBARTin

Treatment of steatorrhea in patients with short bowel syndrome Intrathecal treatment of neuropathic pain associated with spinal cord injury

Contulakin-G

Cordycepin Corticorelin ovine triflutate

Acthrel

Treatment of TdT-positivepituitary acute lymphocytic For use in differentiating and ectopic leukemia production of ACTH in patients with ACTH-dependent Cushings syndrome.

Corticotropin-releasing factor, human

Xerecept

Treatment of peritumoral brain edema.

Coumarin

Onkolox

Treatment of renal cell carcinoma.

Coxsackievirus A21

Cavatak

Treatment of stage II (T4), stage III, and stage IV melanoma

Creatine

Creapure

Treatment of Huntington's disease

creatine

Creapure

Treatment of amyotrophic lateral sclerosis

Cromolyn sodium

Gastrocrom

Treatment of mastocytosis.

Cromolyn sodium 4% ophthalmic solution

Opticrom 4% ophthalmic Treatmentsolution of vernal keratoconjunctivitis.

Cryptosporidium hyperimmune bovine colostrum IgG concentrate

Treatment of diarrhea in AIDS patients caused by infection with for Cryptosporidium parvum. As a therapy primary immune deficiency resulting

cultured, partially T-Cell depleted, allogenic thymic tissue for transplantation CY-1503

CY-1503

Cylexin

from athymia associated with complete DiGeorge Syndrome Treatment of neonates and infants undergoing cardiopulmonary bypass during surgical repair of congenital heart lesions.

Cylexin

Treatment of post-ischemic pulmonary reperfusion edema following surgical treatment for chronic thromboembolic pulmonary hypertension. Treatment of chronic active hepatitis B infection in HLA-A2 positive patients.

CY-1899 Cyclo {{(E,Z)-(2S,3R,4R)-3-hydroxy-4-methyl2-(methylamino)nona-6,8-dienoyl}-L-2aminobytyrl-N-methyl-glycyl-N-methyl-Lleucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-Dalanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-Nmethyl-L-valyl}

Treatment and chronic control of non-infectious posterior, intermediate and pan-uveitis

Prophylaxis of organ rejection in patients receiving allogeneic lung transplant

cyclosporin

Cyclosporin A

Cyclosporin

Treatment of amyotrophic lateral sclerosis and its variants

cyclosporine

Pluminiq

Treatment of acute rejection in patients requiring allogenic lung transplants.

Cyclosporine 2% ophthalmic ointment

Treatment of patients at high risk of graft rejection following penetrating keratoplasty. For use in corneal melting syndromes of known or presumed immunologic etiopathogenesis, including Mooren's ulcer.

cyclosporine A

Treatment of vernal keratoconjunctivitis

Cyclosporine A implant

For the prevention of acute rejection in cornea transplant patients

Cyclosporine in combination with omega-3 polyunsaturated fatty acids

Prevention of solid organ graft rejection.

Cyclosporine 2% ophthalmic ointment

Cyclosporine ophthalmic

Optimmune

Treatment of severe keratoconjunctivitis sicca associated with Sjogren's syndrome.

Cyproterone acetate

Androcur

Treatment of severe hirsutism.

Cysteamine

Cysteamine

Treatment of nephropathic cystinosis.

Cystagon

Treatment of nephropathic cystinosis.

Cysteamine hydrochloride

Treatment of corneal cystine crystal accumulation in cystinosis patients.

Cystic fibrosis gene therapy

Treatment of cystic fibrosis.

Cystic fibrosis Tr gene therapy (recombinant adenovirus) Cystic fibrosis transmembrane conductance regulator

AdGVCFTR.10 Treatment of cystictransmembrane fibrosis. For cystic fibrosis conductance

regulator protein replacement therapy in cystic fibrosis patients.

Cystic fibrosis transmembrane conductance regulator gene

Treatment of cystic fibrosis.

Cytarabine liposomal

DepoCyt

Treatment of neoplastic meningitis.

cytarabine liposome

DepoCyt

Treatment of gliomas For use in prevention of clinically significant CMV viremia, CMV disease and associated complications in at-risk hematopoietic cell transplant and solid organ transplant populations Prevention of clinically significant cytomegalovirus (CMV) viremia, CMV disease and asociated complications in at-risk hematopoietic cell transplant and solid transplant populations

Cytomegalovirus DNA Vaccine w/Copolymer/Benzalkonium Chloride Cytomegalovirus DNA vaccine with plasmids expressing pp65 and gB genes

Cytomegalovirus immune globulin (human) Cytomegalovirus immune globulin intravenous (human)

CytoGam

Prevention or attenuation of primary cytomegalovirus disease in immunosuppressed recipients of organ transplants. For use in conjunction with ganciclovir sodium for the treatment of cytomegalovirus pneumonia in bone marrow transplant patients.

Daclizumab

Zenapax

Prevention of acute renal allograft rejection.

Dantrolene sodium

Dantrium

Treatment neuroleptic malignant syndrome. Prophylaxisofofthe toxoplasmosis in severely immunocompromised patients with CD4 counts below 100.

Dapsone Dapsone USP

Dapsone

For the combination treatment of Pneumocystis carinii pneumonia in conjunction with trimethoprim.

Dapsone USP

Dapsone

Prophylaxis for Pneumocystis carinii pneumonia.

Dasatinib

Sprycel

Treatment of Philadelphia-positive acute lymphoblastic leukemia

Dasatinib

Sprycel

Treatment of chronic myelogenous leukemia

Daunorubicin citrate liposome injection

DaunoXome

Treatment of patients with advanced HIV-associated Kaposi's sarcoma.

DEAE-rebeccamycin

Treatment of bile duct tumors

debrase

Debridase

Debridement of acute, deep dermal burns in hospitalized patients

Decitabine

Dacogen

Treatment of acute myeloid leukemia

decitabine

Treatment of sickle cell anemia

Decitabine

Treatment of chronic myelogenous leukemia.

Decitabine

Dacogen

Deferasirox

Exjade

deferiprone

Ferriprox

Treatment of myelodysplastic syndromes. Treatment of chronic iron overload in patients with transfusion-dependent anemias Treatment of iron overload in patients with hematologic disorders requiring chronic transfusion therapy

deferoxamine-starch conjugate

Treatment of acute iron poisoning.

defibrotide

For the prevention of hepatic veno-occlusive disease.

Defibrotide

For the treatment of hepatic veno-occlusive disease

Defibrotide

Treatment of thrombotic thrombocytopenic purpura. Treatment of systemic lupus erythematosus (SLE) and the reduction in the use of steroids in steroiddependent SLE patients.

Dehydroepiandrosterone

Dehydroepiandrosterone (DHEA)

Fidelin

Replacement therapy in individuals with adrenal insufficiency

Dehydroepiandrosterone sulfate sodium

Treatment of serious burns requiring hospitalization.

Dehydroepiandrosterone sulfate sodium

To accelerate the re-epithelialization of donor sites in those hospitalized burn patients who must undergo autologous skin grafting.

Denileukin diftitox

Ontak

Deslorelin

Somagard

Treatment of patients with Cutaneous T-cell Lymphoma.

Desmoglein 3 synthetic peptide (PI-0824)

Treatment of pemphigus vulgaris

Desmopressin acetate

Treatment of mild hemophilia A and von Willebrand's disease.

Dexamethasone

Posurdex

dexanabinol

For use in posterior segment drug delivery system in the treatment of idiopathic intermediate uveitis. For the attenuation or amelioration of the long-term neurological sequelae associated with moderate and severe traumatic brain injury

dexrazoxane

Totect

Treatment of anthracycline extravasation during chemotherapy

Dexrazoxane

Zinecard

For the prevention of cardiomyopathy associated with doxorubicin administration.

dextran 1

Treatment of cystic fibrosis

Dextran 70

Dehydrex

Treatment of recurrent corneal erosion unresponsive to conventional therapy.

Dextran and deferoxamine

Bio-Rescue

Treatment of acute iron poisoning.

Dextran sulfate (inhaled, aerosolized)

Uendex

For use as an adjunct to the treatment of cystic fibrosis.

Dextran sulfate sodium

Treatment of aquired immunodeficiency syndrome.

DHA-paclitaxel

Taxoprexin

Treatment of pancreatic cancer

DHA-paclitaxel

Taxoprexin

Treatment of adenocarcinoma of the stomach or lower esophagus

DHA-paclitaxel

Taxoprexin

Treatment of metastatic malignant melanoma

For use as a nutritional supplement for the treatment Dianeal peritoneal dialysis solution with 1.1% of malnourishment in patients undergoing continuous Nutrineal (Peritoneal Dialysis Solution with 1.1% Amino Acid amino acids ambulatory peritoneal dialysis. For the management of selected, refractory, patients with epilepsy, on stable regimens of antiepileptic drugs (AEDs), who require intermittent use of Diazepam viscous solution for rectal diazepam to control bouts of increased seizure administration activity. Diaziquone

Treatment of primary brain malignancies (grade III and IV astrocytomas).

Dideoxyinosine

Treatment of acquired immunodeficiency syndrome.

Diethyldithiocarbamate

Imuthiol

Treatment of AIDS.

diethylenetriaminepentaacetate (DPTA)

For treatment of patients with known or suspected internal contamination with plutonium, americium or curium to increase the rates of elimination.

Diethylenetriaminepentaacetic acid (DTPA)

Treatment of patients with known or suspected internal contamination with plutonium, americium, or curium to increase the rates of elimination.

Diethylnorspermine (DENSPM)

Treatment for hepatocellular carcinoma

diferuloylmethane

Treatment of cystic fibrosis

Digitoxin

Treatment of cystic fibrosis

digitoxin

Treatment of soft tissue sarcomas

digitoxin Digoxin immune FAB (Ovine)

Digibind

Digoxin immune fab(ovine)

Digidote

Treatment of ovarian cancer Treatment of potentially life threatening digitalis intoxication in patients who are refractory to management by conventional therapy. Treatment of life-threatening acute cardiac glycoside intoxication manifested by conduction disorders, ectopic ventricular activity and (in some cases) hyperkalemia.

dihydroartemisinin and piperaquine

Eurartesim

Treatment of uncomplicated malaria caused by "Plasmodium falciparum," Plasmodium vivax," Plasmodium malariae," or "Plasmodium ovale."

Dihydrotestosterone

Androgel -DHT associated wasting.

Treatment of weight loss in AIDS patients with HIV-

Dimethyl sulfoxide

Treatment of increased intracranial pressure in patients with severe, closed-head injury, also known as traumatic brain coma, for whom no other effective treatment is available.

Dimethyl sulfoxide

Treatment of cutaneous manifestations of scleroderma.

Dimethylsulfoxide

Treatment of palmar-plantar erythrodysethesia syndrome.

Dimethylsulfoxide

Topical treatment for the prevention of soft tissue injury following extravastion of cytotoxic drugs.

Dipalmitoylphosphatidylcholine /phosphatidylglycerol

ALEC

Treatment of chronic severe forms of alopecia areata (Alopecia Totalis [AT]/Alopecia Universalis [AU])

diphenylcyclopenone Disaccharide tripeptide glycerol dipalmitoyl

Prevention and treatment of neonatal respiratory distress syndrome.

Immther

Disodium clodronate

Treatment of pulmonary and hepatic metastases in patients with colorectal adenocarcinoma.

Treatment of hypercalcemia of malignancy.

Disodium clodronate tetrahydrate

Bonefos

Treatment of increased bone resorption due to malignancy.

Disodium silibinin dihemisuccinate

Legalon

Treatment of hepatic intoxication by Amanita phalloides (mushroom poisoning).

DMP 777

Therapeutic management of patients with lung disease attributable to cystic fibrosis.

DNA plasmid vector expressing human IL-12 gene

Treatment of ovarian cancer.

DNA-lipid complex (DMRIE/DOPE)/plasmid vector (VCL-1102, Vical) expressing human interleukin-2

Leuvectin

Treatment of renal cell carcinoma.

DNP-Modified autologous tumor vaccine

O-Vax

Adjuvant therapy for the treatment of ovarian cancer

docosahexanoic acid-paclitaxel

Taxoprexin

Treatment of hormone-refractory prostate cancer. Treatment of bronchopulmonary infection in patients with cystic fibrosis who are colonized with Pseudomonas aeruginosa or Burkholderia cepacia.

Doripenem

Dornase alfa

Pulmozyme

Dovitinib

Doxorubicin HCL liposome injection

To reduce mucous viscosity and enable the clearance of airway secretions in patients with cystic fibrosis.

Treatment of multiple myeloma

Doxil

Doxorubicin HCl with pluronic L-61 and pluronic F-127

Treatment of multiple myeloma

Treatment of esophageal carcinoma

Doxorubicin liposome

Doxil

doxorubicin PIHCA nanoparticles

Doxorubicin Transdrug Treatment of hepatocellular carcinoma

D-peptide of the sequence AKRHHGYKRKFH PulmaDex - NH2 Dronabinol

Marinol

Treatment of ovarian cancer.

Treatment of cystic of fibrosis For the stimulation appetite and prevention of weight loss in patients with a confirmed diagnosis of AIDS.

Droxidopa

Treatment of neurogenic symptomatic orthostatic hypotension in patients with primary autonomic failure, dopamine-beta-hydroxylase deficiency, and nondiabetic autonomic neuropathy.

Duramycin

Treatment of cystic fibrosis.

Dynamine

Treatment of hereditary motor and sensory neuropathy type I (Charcot-Marie-Tooth disease).

Dynamine

Treatment of Lambert Eaton myasthenic syndrome.

eculizumab

Idiopathic membranous glomerular nephropathy

eculizumab

Soliris

Edotreotide

OctreoTher

Treatment of paroxysmal nocturnal hemoglobinuria

Efaproxiral

Treatment of somatostatin receptor-positive neuroendocrine gastroenteropancreatic tumors Adjunct to whole brain radiation therapy for the treatment of brain metastases in patients with breast cancer

Eflornithine

Treatment of anaplastic glioma

Eflornithine HCl

Ornidyl

Treatment of Pneumocystis carinii pneumonia in AIDS patients.

Eflornithine HCl

Ornidyl

Treatment of Trypanosoma brucei gambiense infection (sleeping sickness).

Elcatonin

Intrathecal treatment of intractable pain.

Enadoline hydrochloride

Treatment of severe head injury.

Encapsulated porcine islet preparation

BetaRx

Treatment of type I diabetic patients who are already on immunosuppression.

Eniluracil

Treatment of hepatocellular carcinoma

Enisoprost

For use in organ transplant patients to diminish the nephrotoxicity induced by cyclosporine.

Enisoprost

For use with cyclosporine in organ transplant recipients to reduce acute transplant rejection.

Enteric-coated cysteamine

Treatment of cystinosis

Enzastaurin Epidermal growth factor (human)

Treatment of glioblastoma For acceleration of cornealmultiforme epithelial regeneration and the healing of stromal tissue in the condition of nonhealing corneal defects.

Epidermal growth factor (human)

For promotion of cutaneous wound healing in extreme burn treatment protocols.

Epirubicin

Ellence

Treatment of breast cancer.

Epoetin alfa

Epogen

Treatment of anemia associated with HIV infection or HIV treatment.

Epoetin alfa

Epogen

Treatment of anemia associated with end stage renal disease.

Epoetin alfa

Treatment of myelodysplastic syndrome.

Epoetin alpha

Procrit

Treatment of anemia associated with end stage renal disease.

Epoetin alpha

Procrit

Treatment of anemia of prematurity in preterm infants.

Epoetin alpha

Procrit

Treatment of HIV associated anemia related to HIV infection or HIV treatment.

Epoetin beta

Marogen

Treatment of anemia associated with end stage renal disease.

Epoprostenol

Flolan

Treatment of secondary pulmonary hypertension due to intrinsic precapillary pulmonary vascular disease.

Epoprostenol

Flolan

Epoprostenol

Flolan

Epoprostenol

Cycloprostin

hemodialysis and who are at increased risk of hemorrhage.

epratuzumab

LymphoCIDE

Treatment of non-Hodgkin's lymphoma.

Eprodisate

Fibrillex

Treatment of secondary amyloidosis

Treatment of primary pulmonary hypertension. Replacement of heparin in patients requiring hemodialysis and who are at increased risk of hemorrhage. Replacement of heparin in patients requiring

Prevention and treatment of EBV-post transplant lymphoproliferative disease after hematopoietic stem cell transplant or solid organ transplant.

Epstein Barr Virus specific cytotoxic T lymphocytes

Erlotinib Hydrochloride

Tarceva

Treatment of malignant gliomas

Erwinia L-asparaginase

Erwinase

Erwinia L-asparaginase

Treatment of acute lymphocytic leukemia. For use as an alternative to E. coli asparaginase in those situations where repeat courses of asparaginase therapy for acute lymphoblastic leukemia are required or where allergic reactions force the discontinuance of the E. coli preparation.

Erythropoietin (human, recombinant)

Treatment of anemia associated with end stage renal disease.

Erythropoietin (recombinant human)

Treatment of anemia associated with end stage renal disease.

Estradiol Gel

EstroGel

Etanercept

Enbrel

Estrogen replacement therapy in females with Turner Reduction in signs and symptoms of moderately to syndrome severely active polyarticular-course juvenile rheumatoid arthritis in patients who have had an inadequate response to one or more diseasemodifying anti-rheumatic drugs.

Ethanol gel

Treatment of congenital lymphatic malformations

Ethanol gel

Treatment of congenital venous malformations

Ethanolamine oleate

Ethamolin

Treatment of patients with esophageal varices that have recently bled, to prevent rebleeding.

Ethinyl Estradiol, USP

Treatment of Turner's syndrome.

Ethiofos

Use as a chemoprotective agent for cisplatin and cyclophosphamide in the treatment of ovarian cancer.

Ethyl eicosapentaenoate

Treatment of Huntington's disease.

Etidronate disodium

Prevention of degenerative metabolic bone disease occurring in patients who require long term (6 months Didronel IV infusion or greater) total parenteral nutrition.

Etidronate disodium

Treatment of degenerative metabolic bone disease occurring in patients who require long term (6 months Didronel IV Infusion or greater) of total parenteral nutrition. Treatment hypercalcemia of malignancy

Etidronate disodium

Didronel

inadequately managed by dietary modification and/or oral hydration.

Etiocholanedione

Treatment of Prader-Willi syndrome.

Etiocholanedione

Treatment of aplastic anemia.

Ex vivo cultured adult human mesenchymal stem cells

Prochymal

Exemestane

Aromasin

Exisulind

Treatment graftbreast versuscancer host disease Treatment of of acute advanced in postmenopausal women whose disease has progressed following tamoxifen therapy. For the suppression and control of colonic adenomatous polyps in the inherited disease adenomatous polyposis coli.

Factor XIII [A2] homodimer, recombinant DNA origin

Treatment of congenital FXIII deficiency

Factor XIII [A2} homodimer, recombinant DNA origin

For the prophylaxis of bleeding associated with congential FXIII deficiency

factor XIII concentrate (human), pasteurized

Fibrogammin P Treatment of congenital factor XIII deficiency.

Factor XIII, recombinant

Fampridine

Treatment of congenital factor XIII deficiency.

Neurelan

Treatment of chronic, incomplete spinal cord injury.

Fampridine

Neurelan

Relief of symptoms of multiple sclerosis.

Felbamate

Felbatol

Treatment of Lennox-Gastaut syndrome.

Fenobam hydrochloride

Treatment of fragile X syndrome

fenretinide

Treatment of Ewing's sarcoma family of tumors.

Fenretinide ferric hexacyanoferrate (II) "Prussian Blue"

Treatment of neuroblastoma Treatment of patients with known or suspected internal contamination with radioactive or nonradioactive cesium or thallium

FIAU

Adjunctive treatment of chronic active hepatitis B. For the control of bleeding and prophylactic treatment of patients deficient in fibrinogen. Treatment of non-healing corneal ulcers or epithelial defects which have been unresponsive to conventional therapy and the underlying cause has been eliminated. Treatment of non-healing corneal ulcers or epithelial defects which are unresponsive to conventional therapy and for which any infectious cause of the defect has been eliminated.

Fibrinogen (human)

Fibronectin (human plasma derived)

Fibronectin (plasma derived)

Filgrastim

Neupogen

Treatment of patients with severe chronic neutropenia (absolute neutrophil count less than 500/mm3).

Filgrastim

Neupogen

Treatment of myelodysplastic syndrome.

Filgrastim

Neupogen

Filgrastim

Neupogen

Filgrastim

Neupogen

Filgrastim

Neupogen

Floxuridine, FUDR

Treatment of neutropenia associated with bone marrow transplants. Reduction in the duration of neutropenia, fever, antibiotic use, and hospitalization, following induction and consolidation treatment for acute myeloid leukemia. Treatment of patients with AIDS who, in addition, are afflicted with cytomegalovirus retinitis and are being treated with ganciclovir. For use in the mobilization of peripheral blood progenitor cells for collection in patients who will receive myeloablative or myelosuppressive chemotherapy.

Intraperitoneal treatment of gastric cancer.

Fludarabine phosphate

Fludara

Treatment of chronic lymphocytic leukemia (CLL), including refractory CLL.

Fludarabine phosphate

Fludara

Treatment and management of patients with nonHodgkins lymphoma.

Flumecinol

Zixoryn

Treatment of hyperbilirubinemia in newborn infants unresponsive to phototherapy.

Flunarizine

Sibelium

Treatment of alternating hemiplegia.

Fluocinolone

Retisert

Treatment uveitis involving the posterior segment of the eye.

Fluorouracil

Adrucil

For use in combination with leucovorin for therapy of metastatic adenocarcinoma of the colon and rectum. For use in combination with interferon alpha-2a,

Fluorouracil

recombinant, for the treatment of esophageal carcinoma. For use in combination with interferon alpha-2a, recombinant, for the treatment of advanced colorectal carcinoma.

Fluorouracil

Treatment of glioblastoma multiforme.

Fluorouracil

Fluoxetine

Prozac

Treatment of body dysmorphic disorder in children and adolescents

Fluoxetine

Prozac

Treatment of autism.

Follitropin alfa, recombinant

Gonal-F

For the initiation and re-initiation of spermatogenesis in adult males with reproductive failure due to hypothalamic or pituitary dysfunction, hypogonadotropic hypogonadism. AMENDED indication 6/27/00: For the induction of spermatogenesis in men with pr

Fomepizole

Antizole

Treatment of methanol or ethylene glycol poisoning.

Fomepizole

Antizole

Treatment of methanol or ethylene glycol poisoning.

Fosphenytoin

Cerebyx

For the acute treatment of patients with status epilepticus of the grand mal type.

Fructose-1,6-diphosphate Fusion protein consisting of human immunoglobim G1 constant region Fc region fused to the human receptor binding domain of ectodysplasin-A1

Cordox

Treatment of painful vaso-occlusive episodes associated with sickle cell disease. Treatment of X-linked hypohidrotic ectodermal dysplasia

G17DT Immunogen

Treatment of gastric cancer

G17DT Immunogen

Treatment of adenocarcinoma of the pancreas

Gabapentin

Neurontin

Treatment of amyotrophic lateral sclerosis.

Gallium nitrate injection

Ganite

Treatment of hypercalcemia of malignancy. Treatment of narcolepsy and the auxiliary symptoms of cataplexy, sleep paralysis, hypnagogic hallucinations and automatic Treatment of narcolepsy and behavior. the auxiliary symptoms

Gamma hydroxybutyrate Gamma-hydroxybutyric acid

of cataplexy, sleep paralysis, hypnagogic hallucinations, and automatic behavior.

Gammalinolenic acid

Treatment of juvenile rheumatoid arthritis.

Ganaxolone

Treatment of infantile spasms. Treatment of acute herpetic keratitis (dendritic and geographic ulcers)

Ganciclovir

Virgan

Ganciclovir intravitreal implant

Vitrasert Implant Treatment of cytomegalovirus retinitis.

Ganciclovir sodium

Cytovene

infections in specific immunosuppressed patient populations.

Gancyclovir

Gangliosides as sodium salts

Cronassial

Gavilimomab

Gemtuzumab zogamicin Gene plasmid hVEGF165 driven by human cytomegalovirus, and [2,3bis(oleoyl)propyl]trimethyl ammonium and dioleoyl phosphatidyl ethanolamine

Treatment of cytomegalovirus retinitis in immunocompromised patients with AIDS. Treatment of severe human cytomegalovirus

Treatment of retinitis pigmentosa.

Acute graft-versus-host disease (aGVHD)

Mylotarg

Treatment of CD33-positive acute myeloid leukemia.

Trinam

Prevention of complications due to neointimal hyperplasia disease in certain vascular anastomoses.

genetically engineered herpes simplex virus (G207)

Tretament of malignant glioma

Geneticin

Treatment of amoebiasis.

Gentamicin impregnated PMMA beads on surgical wire

Septopal

Treatment of chronic osteomyelitis of post-traumatic, postoperative, or hematogenous origin.

Gentamicin liposome injection

Maitec

Treatment of disseminated Mycobacterium aviumintracellulare infection.

Glatiramer acetate

Copaxone

Treatment of multiple sclerosis.

Glatiramer acetate for injection

Copaxone

Treatment of primary-progressive multiple sclerosis

glucarpidase

Voraxaze

Glutamine

NutreStore

Treatment of patients at risk of methotrexate toxicity For use with human growth hormone in the treatment of short bowel syndrome (nutrient malabsorption from the gastrointestinal tract resulting from an inadequate absorptive surface). To decrease intracranial hypertension and/or alleviate

Glyceol

cerebral edema in patients who may benefit from osmotherapy.

Glyceryl tri (4-phenylbutyrate)

Treatment of spinal muscular atrophy

Glyceryl trioleate and glyceryl trierucate

Treatment of adrenoleukodystrophy.

Glycopyrrolate

Treatment of pathologic (chronic moderate to severe) drooling in pediatric patients

Golimumab

Gonadorelin acetate

Lutrepulse

Treatment of chronic sarcoidosis For induction of ovulation in women with hypothalamic amenorrhea due to a deficiency or absence in the quantity or pulse pattern of endogenous GnRH secretion.

Gossypol

Treatment of cancer of the adrenal cortex.

Gp100 adenoviral gene therapy

Treatment of metastatic melanoma.

Granulocyte macrophage-colony stimulating factor

Leucomax

Treatment of severe thermal injuries in patients with greater than 40% full or partial thickness burns.

Granulocyte macrophage-colony stimulating factor

Leucomax

Treatment of chronic lymphocytic leukemia to increase granulocyte count.

Granulocyte macrophage-colony stimulating factor

Leucomax

Treatment of myelodysplastic syndrome.

Granulocyte macrophage-colony stimulating factor

Leucomax

Treatment of neutropenia associated with bone marrow transplants.

Granulocyte macrophage-colony stimulating factor

Leucomax

Treatment of neutropenia due to hairy cell leukemia. Treatment of neonates for disseminated group B streptococcal infection. For the long-term treatment of children who have

Group B streptococcus immune globulin

growth failure due to a lack of adequate endogenous growth hormone secretion.

Growth hormone releasing factor Guanethidine monosulfate

Ismelin

Treatment of moderate to severe reflex sympathetic dystrophy and causalgia.

Guanfacine

Tenex

Treatment of fragile X syndrome.

Gusperimus

Spanidin

Treatment of acute renal graft rejection episodes.

h5G1.1-mAb

Treatment of dermatomyositis

Halofantrine

Halfan

Treatment of mild to moderate acute malaria caused by susceptible strains of P. falciparum and P. vivax.

Halofuginone

Stenorol

Treatment of systemic sclerosis.

heat killed Mycobacterium w immunomodulator

CADI Mw

Active tuberculosis

heat killed mycobacterium w immunomodulator

CADI Mw

Adjuvant to multi-drug therapy in the management of multibacillary leprosy

Heme arginate

Normosang

Treatment of symptomatic stage of acute porphyria.

Heme arginate

Normosang

Treatment of myelodysplastic syndromes.

Hemin

Panhematin

Amelioration of recurrent attacks of acute intermittent porphyria (AIP) temporarily related to the menstrual cycle in susceptible women and similar symptoms which occur in other patients with AIP, porphyria variegata and hereditary coproporphyria.

Hemin and zinc mesoporphyrin

Hemex

Treatment of acute porphyric syndromes.

Heparin

Treatment of cystic fibrosis

Heparin sodium

Treatment of cystic fibrosis Prevention and treatment of necrotizing enterocolitis (NEC) in preterm infants with birth weight less than 1,500 grams

Heparin-binding epidermal growth factor-like growth factor Hepatitis B immune globulin intravenous (human)

Nabi-HB

Prophylaxis against hepatitis B virus reinfection in liver transplant patients. Prophylaxis of hepatitis C infection in liver transplant recipients. For the prevention of hepatitis B virus (HBV)

Hepatitis C virus immune globulin (human) HepeX-B

reinfection in patients who have received a liver transplantation

Herpes simplex virus gene

Treatment of primary and metastatic brain tumors.

Histamine

Maxamine

For use as an adjunct to cytokine therapy in the treatment of malignant melanoma.

Histamine

Ceplene

Adjunct to cytokine therapy in the treatment of acute myeloid leukemia.

Histrelin

Supprelin LA

Treatment of central precocious puberty Treatment of acute intermittent porphyria, hereditary coproporphyria, and variegate porphyria.

Histrelin

Histrelin acetate

Supprelin Injection Treatment of central precocious puberty.

HIV neutralizing antibodies

Immupath

Treatment of acquired immunodeficiency syndrome.

HLA-B7/Beta2M DNA Lipid (DMRIE/DOPE) Complex

Allovectin-7

Treatment of invasive and metastatic melanoma (Stages II, III, and IV).

homoharringtonine

Treatment for chronic myelogenous leukemia

HPA-23

Treatment of acquired immunodeficiency syndrome.

Hsp E7

Treatment of recurrent respiratory papillomatosis (RRP)

Hu1D10, humanized monoclonal antibody Human acid precursor alpha-glucosidase, recombinant

Remitogen

For use in the treatment of 1D10+ B cell nonHodgkin's lymphoma

Treatment of glycogen storage disease type II.

Human alpha 2,6 sialyltransferase adenoviral gene therapy

Treatment of patients with invasive (malignant) brain and central nervous system tumors lacking alpha 2,6 sialyltransferase.

Human anti-CD30 monoclonal antibody

Treatment of Hodgkin's disease

human anti-CD4 monoclonal antibody

HuMax-CD4

Treatment of mycosis fungoides

Human anti-integrin receptor av monoclonal antibody

Treatment of patients with angiosarcoma

human anti-integrin receptor avb3/avb5 monoclonal antibody

Treatment of patients with high-risk stage II, stage III, and stage IV malignant melanoma

human anti-transforming growth factor beta 1 monoclonal antibody

Treatment of systemic sclerosis

human anti-transforming growth factor-B1,2,3

human gammaglobulin

Treatment fibrosis(CMV) Prevention of of idiopathic congenitalpulmonary cytomegalovirus infection following primary CMV infection in pregnant women Treatment of gastrointestinal disturbances (to include constipation, diarrhea, and abdominal pain) associated with regression-onset autism in pediatric patients.

human gammaglobulin

Treatment of idiopathic inflammatory myopathies

human gammaglobulin

Treatment for juvenile rheumatoid arthritis

Human cytomegalovirus immunoglobulin

Human IgM monoclonal antibody (C-58) To CMV

Centovir

Prophylaxis of cytomegalovirus infections in bone marrow transplant patients.

Human IgM monoclonal antibody (C-58) To CMV

Centovir

Treatment of cytomegalovirus infections in allogenic bone marrow transplant patients.

Human immune globulin

Xepol

Treatment of post-polio syndrome

Human immunodeficiency virus immune globulin

Treatment of AIDS.

Human immunodeficiency virus immune globulin

Treatment of HIV-infected pregnant women and infants of HIV-infected mothers.

Human immunodeficiency virus immune globulin

Hivig

Treatment of HIV-infected pediatric patients.

Human immunoglobin anti-CD30 monoclonal antibody

Treatment of CD30+ T-cell lymphoma

Human immunoglobulin (IgG1k)antiCTLA-4 monoclonal antibody

Treatment of high risk Stage II, Stage III, and Stage IV melanoma

human leukocyte-derived cytokine mixture

For neoadjuvant therapy in pts. w/squamous cell carcinoma of the head and neck

Human monoclonal antibody against plateletderived growth factor D

To slow the progression of IgA nephropathy and delay kidney failure in patients affected by the disease.

Human monoclonal antibody directed against Aerumab 11 serotype 011 Pseudomonas aeruginosa

Treatment of hospital acquired pneumonia caused by serotype 011 positive Pseudomonas aeruginosa

Human monoclonal antibody targeting CCchemokine ligand 2 Human plasma coagulation Factor VIII and human plasma von Willebrand Factor

Wilate

Human telomerase reverse transcriptase peptide vaccine Human T-lymphotropic virus type III Gp160 antigens

Treatment of pancreatic cancer Treatment of von Willebrand disease except for surgical and/or invasive procedures in patients with von Willebrand disease in whom desmopressin is either ineffective or contraindicated

Treatment of pancreatic cancer

Vaxsyn HIV-1

Treatment of AIDS.

Human umbilical tissue-derived cells

Treatment of retinitis pigmentosa

Humanized anti-CD3 monoclonal antibody

Treatment of recent-onset Type I diabetes

humanized anti-human CD16 monoclonal antibody

Humanized anti-human CD2 MAb

MEDI-507

Treatment of adult idiopathic thrombocytopenic purpura For the induction of donor-specific immunologic unresponsiveness resulting in prophylaxis of organ rejection without the need for chronic immunosuppressive therapy, in patients receiving allogeneic renal transplants.

Humanized anti-tac

Zenapax

Prevention of acute graft-vs-host disease following bone marrow transplantation.

Humanized MAb (IDEC-131) to CD40L humanized monoclonal antibody against Shiga-like toxin II

Treatment of systemic lupus erythematosus. To prevent the development of or to decrease the incidence and severity of hemolytic uremic syndrome and associated sequelae of Shiga-like toxinproducing E. coli.

Humanized monoclonal antibody to the high affinity folate alpha receptor

Treatment of ovarian cancer Treatment of emphysema in patients due to alpha-1 antitrypsin deficiency Treatment of severe intrapartum hypertension (diastolic blood pressure greater than or equal to 110 or systolic blood pressure greater than or equal to 160) associated with severe preeclampsia/eclampsia of pregnancy

hyaluronic acid

Hydralazine

Hydroxocobalamin

Cyanokit

Treatment of acute cyanide poisoning

Hydroxocobalamin

Treatment of acute cyanide poisoning

Hydroxycobalamin/sodium thiosulfate

Treatment of severe acute cyanide poisoning.

hydroxyurea

Treatment of pediatric patients with sickle cell anemia.

Hydroxyurea

Droxia

Treatment of patients with sickle cell anemia as shown by the presence of hemoglobin S.

Hypericin

Treatment of glioblastoma multiforme.

Hypericin

Treatment of cutaneous T-cell lymphoma.

I(131)-TM-601 (chlorotoxin)

treatment of malignant glioma

Iboctadekin

Treatment of renal cell carcinoma

ibritumomab tiuxetan

Zevalin

Treatment of B-cell non-Hodgkin's lymphoma.

Ibuprofen i.v. solution

Salprofen

Prevention of patent ductus arteriosus.

Ibuprofen lysine

NeoProfen

Treatment of patent ductus arteriosus.

Icatibant

Treatment of angioedema

Icatibant acetate

Treatment of burn patients hospitalized with burninduced edema

Icodextrin 7.5% with Electrolytes Peritoneal Dialysis Solution

Extraneal (with 7.5% Icodextrin) Peritoneal Dialysis disease and requiring peritoneal dialysisSolutio treatment.

Treatment of those patients having end stage renal

Idarubicin

Idamycin

Treatment of chronic myelogenous leukemia.

Idarubicin

Idamycin

Treatment of myelodysplastic syndromes.

Idarubicin HCl for injection

Idamycin

Treatment of acute myelogenous leukemia, also referred to as acute nonlymphocytic leukemia.

Idarubicin HCl for injection

Idamycin

Treatment of acute lymphoblastic leukemia in pediatric patients.

idebenone

Treatment of Leber's hereditary optic neuropathy.

idebenone

Treatment of Duchenne muscular dystrophy

Idebenone

Treatment of cardiomyopathy associated with Friedreich's ataxia

Idoxuridine

Treatment of nonparenchymatous sarcomas.

idursulfase

Elaprase

Long term enzyme replacement therapy for patients with mucopolysaccharidosis II (Hunter Syndrome)

Ifosfamide

Ifex

Treatment of testicular cancer.

Ifosfamide

Ifex

Treatment of bone sarcomas

Ifosfamide

Ifex

Treatment of soft tissue sarcomas.

IL13-PE38QQR

Treatment of malignant glioma

IL-4 Pseudomonas Toxin Fusion Protein (IL4(38-37)-PE38KDEL)

Treatment of astrocytic glioma.

Iloprost inhalation solution

Ventavis

Treatment of pulmonary arterial hypertension

Iloprost solution for infusion

Treatment of Raynaud's phenomenon secondary to systemic sclerosis.

Iloprost solution for infusion

Treatment of heparin-associated thrombocytopenia.

Imatinib

Gleevec

Treatment of chronic myelogenous leukemia

Imatinib mesylate

Gleevec

Treatment of systemic mastocytosis without the D816V c-kit mutation

Imatinib mesylate

Gleevec

Treatment of myeloproliferative disorders/myelodysplastic syndromes associated with platelet-derived growth factor gene re-arrangements

Imatinib mesylate

Gleevec

Treatment of idiopathic hypereosinophilic syndrome including acute and chronic eosinophilic leukemia

imatinib mesylate

Gleevec

Treatment of Philadelphia-positive acute lymphoblastic leukemia

imatinib mesylate

Gleevec

Treatment of dermatofibrosarcoma protuberans

imatinib mesylate

Gleevec

Treatment of gastrointestinal stromal tumors

Imciromab pentetate

Myoscint

Detecting early necrosis as an indication of rejection of orthotopic cardiac transplants.

imexon

Amplimexon

Treatment of ovarian cancer.

Imexon

Treatment of multiple myeloma.

Imexon

Treatment of pancreatic adenocarcinoma

Imexon

Treatment of metastatic malignant melanoma

Imiglucerase

Cerezyme

Replacement therapy in patients with types I, II, and III Gaucher's disease.

Immortalized human liver cells found in the extracorporeal liver assist device

ELAD

Treatment of fulminant hepatic failure (acute liver failure)

Immune Globulin (Human)

Gamunex

Treatment of chronic inflammatory demyelinating polyneuropathy

Immune Globulin (Human) containing high titers of West Nile virus antibodies

Omr-IgG-am (tm)Treatment 5% (WNV) of the West Nile virus infection

Immune Globulin Intravenous (human)

Carimune NF

Immune globulin intravenous (human)

Gammagard Liquid Treatment of multifocal motor neuropathy

Immune globulin intravenous (human)

Immune GlobulinTreatment Intravenous (human) Iveegam of patients withImmuno, acute myocarditis.

Immune globulin intravenous (human)

Iveegam, Immuno Treatment of polymyositis/dermatomyositis.

Immune globulin intravenous (human)

Iveegam, Immuno Treatment of juvenile rheumatoid arthritis.

Immune globulin intravenous, human

Gamimune N

Immune Globulin Subcutaneous (Human)

Treatment for Guillain Barre Syndrome

Infection prophylaxis in pediatric patients affected with the human immunodeficiency virus. Treatment of patients with primary immune deficiency (PID) that are intolerant to immune globulin intravenous (IGIV) due to severe adverse events or Vivaglobin P (proposed) poor venous access

Imported fire ant venom, allergenic extract

Treatment of homozygous familial hypercholesterolemia For skin testing of victims of fire ant stings to confirm fire ant sensitivity and if positive, for use as immunotherapy for the prevention of IgE-mediated anaphylactic reactions.

Inalimarev and falimarev

Treatment of adenocarcinoma of the pancreas

Implitapide

Indium In 111 murine monoclonal antibody FAB to myosin

Myoscint

To aid in the diagnosis of myocarditis.

Indium In-111 altumomab pentetate

Hybri-ceaker

Detection of suspected and previously unidentified tumor foci of recurrent colorectal carcinoma.

Indium-111 pentetreotide

NeuroendoMedixTreatment of neuroendocrine tumors

infliximab

Remicade

Treatment of juvenile rheumatoid arthritis

infliximab

Remicade

Treatment of giant cell arteritis

Infliximab

REMICADE

Treatment of pediatric (0 to 16 years of age) ulcerative colitis

Infliximab

REMICADE

Treatment of pediatric (0 to 16 years of age) Crohn's Disease

Infliximab

Remicade

Treatment of chronic sarcoidosis

Infliximab

Remicade

Treatment of moderately to severely active Crohn's disease for the reduction of the signs and symptoms, in patients who have an inadequate response to conventional therapy; and treatment of patients with fistulizing Crohn's disease for the reduction in th

INGN 201

ADVEXIN

INH-A00021

Veronate

Treatment of head andof neck cancer bacteremia Reduction (prevention) nosocomial caused by staphylococci in very low birth weight infants.

inolimomab

Leukotac

Treatment of graft versus host disease

Inosine pranobex

Isoprinosine

Treatment of subacute sclerosing panencephalitis.

Interferon alfa-2a

Roferon A

Treatment of chronic myelogenous leukemia.

Interferon alfa-2a (recombinant)

Roferon-A

Treatment of renal cell carcinoma.

Interferon alfa-2a (recombinant)

Roferon-A

For the treatment of metastatic malignant melanoma in combination with Teceleukin.

Interferon alfa-2a (recombinant)

Roferon-A

For the concomitant administration with Teceleukin for the treatment of metastatic renal cell carcinoma.

Interferon alfa-2a (recombinant)

Roferon-A

Treatment of AIDS related Kaposi's sarcoma.

Interferon alfa-2a (recombinant)

Roferon-A

For the concomitant administration with fluorouracil for the treatment of advanced colorectal cancer.

Interferon alfa-2a (recombinant)

Roferon-A

For use in combination with fluorouracil for the treatment of esophageal carcinoma.

Interferon alfa-2b (recombinant)

Intron A

Treatment of AIDS-related Kaposi's sarcoma.

Interferon alfa-2b (recombinant)

Intron A

Treatment of acute hepatitis B.

Interferon alfa-2b (recombinant)

Intron A

Treatment of primary malignant brain tumors.

Interferon alfa-2b (recombinant)

Intron A

Treatment of carcinoma in situ of the urinary bladder.

Interferon alfa-2b (recombinant)

Intron A

Treatment of invasive carcinoma of the cervix.

Interferon alfa-2b (recombinant)

Intron A

Treatment of ovarian carcinoma.

Interferon alfa-2b (recombinant)

Intron A

Treatment of chronic myelogenous leukemia.

Interferon alfa-2b (recombinant)

Intron A

Treatment of metastatic renal cell carcinoma.

Interferon alfa-2b (recombinant)

Intron A

Treatment of laryngeal (respiratory) papillomatosis.

Interferon alfa-2b (recombinant)

Intron A

Interferon alfa-nl

Wellferon

Treatment delta hepatitis. in patients with Treatment of of chronic human papillomavirus severe resistant/recurrent respiratory (laryngeal) papillomatosis.

Interferon alfa-nl

Wellferon

Treatment of AIDS related Kaposi's sarcoma.

Interferon beta (recombinant)

R-IFN-beta

For the systemic treatment of metastatic renal cell carcinoma.

Interferon beta (recombinant)

r-HuIFN-beta

For the intralesional and/or systemic treatment of AIDS-related Kaposi's sarcoma.

Interferon beta (recombinant)

r-HuIFN-beta

For the systemic treatment of cutaneous T-cell lymphoma.

Interferon beta, recombinant human

Betaseron

Treatment of acquired immunodeficiency syndrome.

Interferon beta-1a

Rebif

Treatment of patients with secondary progressive multiple sclerosis.

Interferon beta-1a

Avonex

Treatment of multiple sclerosis.

Interferon beta-1a (recombinant human)

Treatment of acute non-A, non-B hepatitis.

Interferon beta-1a (recombinant)

r-HuIFN-beta

Interferon beta-1a (recombinant)

Rebif

For the systemic treatment of cutaneous malignant melanoma. Treatment of symptomatic patients with AIDS including all patients with CD4 T-cell counts less than 200 cells per mm3.

Interferon beta-1b

Betaseron

Treatment of multiple sclerosis.

Interferon gamma 1-b

Actimmune

Treatment of chronic granulomatous disease.

Interferon gamma-1b

Actimmune

Delaying time to disease progression in patients with severe, malignant osteopetrosis.

Interferon gamma-1b

Actimmune

Treatment of renal cell carcinoma.

Interferon-alfa-1b

Treatment of multiple myeloma

Interleukin-1 alpha, human recombinant

For hematopoietic potentiation in aplastic anemia.

Interleukin-1 alpha, human recombinant

For the promotion of early engraftment in bone marrow transplantation.

Interleukin-1 receptor antagonist, human recombinant

Antril

Treatment of juvenile rheumatoid arthritis.

Interleukin-1 receptor antagonist, human recombinant

Antril

Prevention and treatment of graft versus host disease in transplant recipients.

Interleukin-1 Trap

Treatment of Still's disease including juvenile rheumatoid arthritis and adult-onset Still's disease

Interleukin-1Trap

Treatment of CIAS1-Associated Periodic Syndromes

Interleukin-2

Teceleukin

In combination with interferon alfa-2a for the treatment of metastatic malignant melanoma.

Interleukin-2

Teleleukin

Treatment of metastatic malignant melanoma.

Interleukin-2

Teceleukin

Treatment of metastatic renal cell carcinoma.

Interleukin-2

Teceleukin

In combination with interferon alfa-2a for the treatment of metastatic renal cell carcinoma. Promotion of erythropoiesis in Diamond-Blackfan anemia (congenital pure red cell aplasia). For sequential administration with sargramostim to accelerate neutrophil and platelet recovery in patients undergoing autologous bone marrow transplantation for the treatment of Hodgkin's disease or nonHodgkin's lymphoma.

Interleukin-3 human (recombinant)

Interleukin-3, human, recombinant Intraoral fluoride releasing system

IFRS

Prevention of dental caries due to radiation-induced xerostomia in patients with head and neck cancer

Intravenous immune globulin

VitiGam

Treatment of Stage IIB to IV malignant melanoma

Iobenguane I 123

For the diagnosis of pheochromocytoma.

Iobenguane I 123

For the diagnosis of neuroblastomas.

iobenguane I 131

Treatment of neuroendocrine tumors

Iobenguane I 131

Ultratrace

Treatment of neuroendocrine tumors For use as a diagnostic adjunct in patients with pheochromocytoma.

Iobenguane Sulfate I 131 Iobenguane Sulfate I-123

OmaClear

For scintigraphic detection, localization and staging of neuroblastoma.

iobenguane sulfate I-123

OmaClear

For the detection, localization, and staging of pheochromocytomas.

Iodine 131 6B-iodomethyl-19-norcholesterol

For use in adrenal cortical imaging.

Iodine I 123 murine monoclonal antibody to alpha-fetoprotein

Detection of alpha-fetoprotein producing germ cell tumors.

Iodine I 123 murine monoclonal antibody to alpha-fetoprotein

Detection of hepatocellular carcinoma and hepatoblastoma.

Iodine I 123 murine monoclonal antibody to hCG

Detection of hCG producing tumors such as germ cell and trophoblastic cell tumors.

Iodine I 131 bis(indiumdiethylenetriaminepentaacetic acid)tyrosyllysine/hMN-14 x m734 F(ab')2 bispecific monoclonal antibody

Pentacea

Iodine I 131 Lym-1 Monoclonal Antibody Iodine I 131 murine monoclonal antibody IgG2a to B cell

Treatment of small-cell lung cancer.

Treatment of B-cell lymphoma.

Immurait, Ll-2-I-131 Treatment of B-cell leukemia and B-cell lymphoma.

Iodine I 131 murine monoclonal antibody to alpha-fetoprotein

Treatment of alpha-fetoprotein producing germ cell tumors.

Iodine I 131 murine monoclonal antibody to alpha-fetoprotein

Treatment of hepatocellular carcinoma and hepatoblastoma.

Iodine I 131 murine monoclonal antibody to hCG

Treatment of hCG producing tumors such as germ cell and trophoblastic cell tumors.

Iodine I-131 radiolabeled chimeric MAb tumor 131IchTNT-1 necrosis treatment (TNT-1B)

Treatment of glioblastoma multiforme and anaplastic astrocytoma.

irofulven

Treatment of renal cell carcinoma.

irofulven

Treatment of ovarian cancer.

iron(III)-hexacyanoferrate(II)

Treatment of patients with known or suspected internal contamination with radioactive or nonradioactive cesium or thallium

Radiogardase

Isobutyramide Isobutyramide

Treatment of sickle cell disease and beta thalassemia. Treatment of beta-hemoglobinopathies and beta-

Isobutyramide oral solution syndromes. thalassemia

Isofagomine tartrate

Treatment of Gaucher disease

Japanese encephalitis vaccine (live, attenuated) Ketoconazole

Nizoral

Prevention Japanese encephalitis. For use withofcyclosporine A to diminish the nephrotoxicity induced by cyclosporine in organ transplantation.

L-2-oxothiazolidine-4-carboxylic acid

Procysteine

Treatment of adult respiratory distress syndrome.

L-2-oxothiazolidine-4-carboxylic acid

Procysteine

L-5-hydroxytryptophan Lactic acid

Treatment of amyotrophic lateral sclerosis.

Treatment of tetrahydrobiopterin deficiency.

Aphthaid

Treatment of severe aphthous stomatitis in severely, terminally immunocompromised patients.

lactic acid bacteria (Lactobacilli, Bifidobacteria, and Steptococci)

Treatment of active chronic pouchitis

lactic acid bacteria (Lactobacilli, Bifidobacteria, and Streptococcus species)

Prevention of disease relapse in patients with chronic pouchitis

Lactobin

Lactobin

L-aminocarnityl-succinyl-leucyl-argininaldiethylacetal

Treatment of AIDS-associated diarrhea unresponsive to initial antidiarrheal therapy. Treatment of Duchenne and Becker muscular dystrophy

Lamotrigine

Lamictal

Lanreotide

Somatuline Depot Treatment for acromegly

laronidase

Aldurazyme

Treatment of patients with mucopolysaccharidosis-I.

Latrodectus immune F(ab)2

Aracmyn

Treatment of black widow spider envenomations

L-Baclofen

Neuralgon

Treatment of intractable spasticity in children with cerebral palsy.

L-baclofen

Neuralgon

Treatment of intractable spasticity associated with spinal cord injury or multiple sclerosis.

Treatment of Lennox-Gastaut syndrome.

L-Baclofen

Treatment of trigeminal neuralgia.

L-baclofen

Treatment of trigeminal neuralgia.

L-cycloserine

Treatment of Gaucher's disease.

L-cysteine

For the prevention and lessening of photosensitivity in erythropoietic protoporphyria.

Leflunomide

Prevention of acute and chronic rejection in patients who have received solid organ transplants.

lenalidomide

Revlimid

Treatment of myelodysplastic syndromes

lenalidomide

Revlimid

Treatment of chronic lymphocytic leukemia.

lenalidomide

Revlimid

Treatment for multiple myeloma

Lentiviral vector encoded with a human betaglobin gene plasmid

Thalagen

Treatment of beta-thalassemia major and betathalassemia intermedia

Lepirudin

Refluden

Treatment of heparin-associated thrombocytopenia type II.

Lestaurtinib

Treatment of acute myeloid leukemia For use in combination with 5-fluorouracil for the

Leucovorin

Leucovorin calcium treatment of metastatic colorectal cancer.

Leucovorin

Leucovorin calcium in the treatment of osteosarcoma.

Leucovorin calcium

Wellcovorin

For use in combination with 5-fluorouracil for the treatment of metastatic colorectal cancer.

leukocyte interlukin

Multikine

Neoadjuvant therapy in patients with Squamous Cell Carcinoma of the Head and Neck

For rescue use after high dose methotrexate therapy

For use as an adjunct to microsurgical peripheral nerve repair.

Leupeptin

Leuprolide acetate

Lupron Injection Treatment of central precocious puberty.

Levocabastine HCl ophthalmic suspension 0.05% Levocarnitine

Carnitor

Levocarnitine

Carnitor

Treatment of vernal keratoconjunctivitis. Treatment of manifestations of carnitine deficiency in patients with end stage renal disease who require dialysis. Treatment of manifestations of carnitine deficiency in patients with end stage renal disease who require dialysis.

Levocarnitine

Carnitor

For the treatment of secondary carnitine deficiency in valproic acid toxicity.

Levocarnitine

Carnitor

For the prevention of secondary carnitine deficiency in valproic acid toxicity.

Levocarnitine

Carnitor

Treatment of zidovudine-induced mitochondrial myopathy.

Levocarnitine

Carnitor

Treatment of pediatric cardiomyopathy.

Levocarnitine

Carnitor

Treatment of primary and secondary carnitine deficiency of genetic origin.

Levocarnitine

Carnitor

Treatment of genetic carnitine deficiency.

Levodopa and carbidopa

Duodopa

Treatment of late stage Parkinson's disease.

Levomethadyl acetate hydrochloride

Orlaam

Treatment of heroin addicts suitable for maintenance on opiate agonists.

L-glutamine

Treatment of sickle cell disease

L-glutamyl-L-tryptophan

Treatment of AIDS-related Kaposi's sarcoma.

liarozole Lidocaine patch 5%

The treatment of congenital ichthyosis For relief of allodynia (painful hypersensitivity), and

Lidoderm Patch chronic pain in postherpetic neuralgia.

Lintuzumab

Treatment of myelodysplastic syndrome.

lintuzumab

Treatment of acute myeloid leukemia.

lintuzumab

Zamyl

Treatment of acute myelogenous leukemia

Liothyronine sodium injection

Triostat

Treatment of myxedema coma/precoma.

Lipid/DNA human cystic fibrosis gene

Treatment of cystic fibrosis.

Liposomal amphotericin B

AmBisome

Treatment of histoplasmosis.

Liposomal amphotericin B

AmBisome

Treatment of visceral leishmaniasis.

Liposomal amphotericin B

AmBisome

Treatment of cryptococcal meningitis.

Liposomal annamycin

Treatment of acute myeloid leukemia

Liposomal annamycin

Treatment of acute lymphoblastic leukemia

Liposomal ciprofloxacin

For the management of bronchiectasis

Liposomal ciprofloxacin for inhalation

Management of cystic fibrosis

LipOva-Pt

Treatment of ovarian cancer

Liposomal cyclosporin A

Cyclospire

For aerosolized administration in the prevention and treatment of lung allograft rejection and pulmonary rejection events associated with bone marrow transplantation.

Liposomal doxorubicin hydrochloride

Sarcodoxome

Treatment of soft tissue sarcomas

Liposomal N-Acetylglucosminyl-NAcetylmuramly-L-Ala-D-isoGln-L-Ala -gylcerolidpalmitoyl

ImmTher

Treatment of osteosarcoma.

Liposomal N-Acetylglucosminyl-NAcetylmuramly-L-Ala-D-isoGln-L-Ala -gylcerolidpalmitoyl

ImmTher

Treatment of Ewing's sarcoma.

Liposomal cisplatin

Liposomal nystatin

Nyotran

Treatment of invasive fungal infections.

liposomal p-ethoxy growth receptor bound protein-2 antisense product

Treatment of chronic myelogenous leukemia

Liposomal prostaglandin E1 injection

Treatment of acute respiratory distress syndrome.

Liposomal-cis-bis-neodecanoato-trans-R,R1,2-diaminocyclohexane-Pt (II)

Aroplatin

Treatment of malignant mesothelioma.

Liposome encapsulated recombinant interleukin-2

Treatment of brain and CNS tumors.

Liposome encapsulated recombinant interleukin-2

Treatment of cancers of the kidney and renal pelvis.

L-leucovorin

Isovorin

Treatment of patients undergoing induction therapy for acute myeloid leukemia. For use in combination chemotherapy with the approved agent 5-fluorouracil in the palliative treatment of metastatic adenocarcinoma of the colon and rectum.

L-leucovorin

Isovorin

For use in conjunction with high-dose methotrexate in the treatment of osteosarcoma.

Lodoxamide tromethamine

Alomide Ophthalmic Solution Treatment of vernal keratoconjunctivitis.

Lisofylline

Loxoribine

Treatment of common variable immunodeficiency.

L-threonine

Treatment of spasticity associated with familial spastic paraparesis.

L-threonine

Threostat

Treatment of amyotrophic lateral sclerosis. Treatment of neuropathic pain associated with spinal cord injury

L-threonyl-L-prolyl-L-prolyl-L-threonine

L-tyrosine-L-serine-L-leucine

CMS-024

Treatment of hepatocellular carcinoma.

Lucinactant

Surfaxin

Prevention of bronchopulmonary dysplasia in premature infants

Lucinactant

Surfaxin

Treatment of bronchopulmonary dysplasia in premature infants.

Lucinactant

Surfaxin

Treatment of meconium aspiration syndrome in newborn infants

Lucinactant

Surfaxin

Treatment of acute respiratory distress syndrome in adults.

Lucinactant

Surfaxin

Treatment of respiratory distress syndrome in premature infants.

Lysine acetylsalicylate injectable

Mafenide acetate solution

Treatment of pain and fever secondary to sickle cell disease crisis. For use as an adjunctive topical antimicrobial agent to control bacterial infection when used under moist dressings over meshed autografts on excised burn Sulfamylon solution wounds.

Mafosfamide

Treatment of neoplastic meningitis

Mammalian target of rapamcyin (mTOR) inhibitor

Treatment of soft tissue sarcoma

Mannitol

For use to facilitate clearance of mucus in patients with bronchiectasis and in patients with cystic fibrosis at risk for bronchiectasis

Bronchitol

mannopentaose phosphate sulfate

Treatment of high-risk Stage II, Stage III, and Stage IV melanoma

maribavir

Prevention of cytomegalovirus viremia and disease in the populations at risk.

Marijuana

Treatment of HIV-associated wasting syndrome.

Matrix metalloproteinase inhibitor

Galardin

MaxAdFVIII

Treatment of corneal ulcers.

Treatment of Hemophilia A

Mazindol

Sanorex

Treatment of Duchenne muscular dystrophy.

Mecamylamine

Inversine

Treatment of Tourette's syndrome.

Mecasermin

Myotrophin

Treatment of amyotrophic lateral sclerosis.

Mecasermin

Increlex

Treatment of growth hormone insensitivity syndrome.

mecasermin rinfabate

iPLEX

Treatment of growth hormone insensitivity syndrome (GHIS)

meclorethamine or nitrogen mustard

Treatment of mycosis fungoides.

MEDI-522

Vitaxin

For the treatment of metastatic melanoma

Medroxyprogesterone acetate

Hematrol

Treatment of immune thrombocytopenic purpura.

Mefloquine HCl

Mephaquin

Prevention of chloroquine-resistant Falciparum malaria.

Mefloquine HCl

Mephaquin

Treatment of chloroquine-resistant Falciparummalaria.

Mefloquine HCl

Lariam

Prophylaxis of Plasmodium falciparum malaria which is resistant to other available drugs.

Mefloquine HCl

Lariam

Treatment of acute malaria due to Plasmodium falciparum and Plasmodium vivax.

Megace

Treatment of patients with anorexia, cachexia, or significant weight loss (=/>10% of baseline body weight) and confirmed diagnosis of AIDS.

Megestrol acetate

Treatment of stage IIIb through IV metastatic melanoma

Melanoma autologous dendritic cell vaccine

Melanoma cell vaccine

Canvaxin

Treatment of invasive melanoma. Treatment of HLA-A2+ patients with stage IIB, IIC, III, and IV malignant melanoma

Melanoma peptide vaccine

Melanoma vaccine

Melacine

Treatment of stage III - IV melanoma.

Melatonin

Circadin

Treatment of non-24-hour sleep-wake disorder in blind individuals without light perception Treatment of circadian rhythm sleep disorders in blind people with no light perception.

Melatonin

meloxicam

Mobic

Melphalan

Alkeran for Injection treat metastatic melanoma of the extremity.

Melphalan

Alkeran For Injection oral therapy is inappropriate.

Treatment of juvenile rheumatoid arthritis For use in hyperthermic regional limb perfusion to Treatment of patients with multiple myeloma for whom

mepivacaine

Treatment of postherpetic neuralgia

Mepivacaine

Treatment of painful HIV-associated neuropathy

mepolizumab

For first-line treatment in patients with hypereosinophilic syndrome Management of acute pulmonary exacerbations, in

Meropenem

Merrem IV

Mesna Mesna

Mesnex

Methionine/L-methionine

cystic fibrosis patients, due to respiratory tract infection with susceptible organisms. Inhibition of the urotoxic effects induced by oxazaphosphorine compounds such as cyclophosphamide.

For use as a prophylactic agent in reducing the incidence of ifosfamide-induced hemorrhagic cystitis.

Treatment of AIDS myelopathy.

Methotrexate

Rheumatrex

Treatment of juvenile rheumatoid arthritis.

Methotrexate sodium

Methotrexate

Treatment of osteogenic sarcoma.

Methotrexate with laurocapram

Methotrexate/azone Topical treatment of mycosis fungoides.

Methoxsalen

Uvadex

For use in conjunction with the UVAR photopheresis system to treat graft versus host disease. Treatment of metabolic disorders secondary to lipodystrophy Treatment of leptin deficiency secondary to

metreleptin

generalized lipodystrophy and partial familial lipodystrophy

metreleptin

Metronidazole

Metrogel

Treatment of perioral dermatitis.

Metronidazole (topical)

Flagyl

Treatment of grade III and IV, anaerobically infected, decubitus ulcers.

Metronidazole (topical)

Metrogel

Treatment of acne rosacea.

Mibefradil Microbubble contrast agent

Treatment of ovarian cancer Intraoperative aid in the identification and localization

Filmix Neurosonographic Contrast Agent of intracranial tumors.

Treatment of non-life threatening, mild to severe bleeding episodes due to cutaneous injuries or dental procedures in hemophiliac patients Treatment of bouts of increased seizure activity in selected refractory patients with epilepsy who are on stable regimens of anti-epileptic drugs and who require intermittent use of midazolam

Microvesiculated modified glycosylated tissue factor

Midazolam HCl

Midodrine HCl

Amatine

Treatment of patients with symptomatic orthostatic hypotension.

mifamuritide

Junovan

Treatment of osteosarcoma Treatment of Cushing's syndrome secondary to ectopic ACTH secretion

Mifepristone mifepristone

Corlux

Treatment of the clinical manifestations of endogenous Cushing's symdrome.

miglustat

Zavesca

Treatment of Gaucher disease.

miltefosine

Impavido

Treatment of leishmaniasis.

Minocycline HCl

Minocin Intravenous Treatment of chronic malignant pleural effusion.

Minocycline hydrochloride

Treatment of sarcoidosis

misoprostol

GyMiso

Treatment of intrauterine fetal death not accompanied by complete expulsion of the products of conception in the second and third trimesters oflymphoma, pregnancy. Treatment of diffuse non-Hodgkin's

Mitoguazone

apep

Mitolactol

including AIDS-related diffuse non-Hodgkin's lymphoma.

Treatment of invasive carcinoma of the uterine cervix

Mitolactol

As adjuvant therapy in the treatment of primary brain tumors.

Mitomycin-C

Treatment of refractory glaucoma as an adjunct to ab externo glaucoma surgery.

Mitoxantrone

Novantrone

Treatment of hormone refractory prostate cancer.

Mitoxantrone

Novantrone

Treatment of secondary-progressive multiple sclerosis.

Mitoxantrone

Novantrone

Treatment of progressive-relapsing multiple sclerosis.

Mitoxantrone HCl

Novantrone

Treatment of acute myelogenous leukemia, also referred to as acute nonlymphocytic leukemia.

MN14 monoclonal antibody to carcinoembryonic antigen

Cea-Cide

Treatment of small cell lung cancer

MN14 monoclonal antibody to carcinoembryonic antigen

Cea-Cide

Treatment of pancreatic cancer.

Modafinil

Provigil

Treatment of excessive daytime sleepiness in narcolepsy.

Molgramostim

Leucomax

Treatment of AIDS patients with neutropenia due to the disease, AZTor ganciclovir.

Molgramostim

Leucomax

Treatment of aplastic anemia.

monarsen Monoclonal Ab(murine) anti-idiotype melanoma-associated antigen

Treatment of Myasthenia Gravis

Melimmune

Monoclonal antibodies (murine or human) to B-cell lymphoma

Monoclonal antibody 17-1a

Treatment of invasive cutaneous melanoma.

Treatment of B-cell lymphoma.

Panorex

Treatment of pancreatic cancer.

Monoclonal antibody for immunization against lupus nephritis

Treatment of lupus nephritis.

Monoclonal antibody to cytomegalovirus (human)

Treatment of cytomegalovirus retinitis in patients with AIDS.

Monoclonal antibody to cytomegalovirus (human)

Prophylaxis of cytomegalovirus disease in patients undergoing organ transplantation. Prophylaxis solid of hepatitis B reinfection in patients

Monoclonal antibody to hepatitis B virus (human)

Monoclonal antibody-B43.13

undergoing liver transplantation secondary to endstage chronic hepatitis B infection.

Ovarex MAb-B43.13 Treatment of epithelial ovarian cancer.

Monoclonal antiendotoxin antibody XMMEn0e5

Treatment of patients with gram-negative sepsis which has progressed to shock.

Monolaurin

Glylorin

Treatment of congenital primary ichthyosis.

Monooctanoin

Moctanin

For dissolution of cholesterol gallstones retained in the common bile duct.

Morphine sulfate concentrate (preservative free)

Infumorph

For use in microinfusion devices for intraspinal administration in the treatment of intractable chronic pain. For use in conjunction with whole brain radiation for

motexafin gadolinium

Xcytrin

the treatment of brain metastases arising from solid tumors

Mucoid exopolysaccharide Pseudomonas hyperimmune globulin

MEP IGIV

Mucoid exopolysaccharide Pseudomonas hyperimmune globulin

Treatment of hepatocellular carcinoma Treatment of pulmonary infections due to Pseudomonas aeruginosa in patients with cystic fibrosis. Prevention of pulmonary infections due to

MEP IGIV

MTC-DOX for Injection

Multi-ligand somatostatin analogue Multi-vitamin infusion (neonatal formula)

Pseudomonas aeruginosa in patients with cystic fibrosis. Treatment of patients with functional gastroenteropancreatic (GEP) neuroendocrine tumors (specifically, carcinoid, insulinoma, gastrinoma, somastatinoma, GRFoma, VIPoma and glucagonoma. For establishment and maintenance of total parenteral nutrition in very low birth weight infants. Prevention of vitamin deficiency and thromboembolic complications in people receiving home parenteral nutrition and warfarin-type anticoagulant therapy

multi-vitiam infusion without vitamin K

M.V.I.-12

Murine MAb (Lym-1) and Iodine 131-I radiolabeled murine MAb (Lym-1) to human B-cell lymphoma

Oncolym

Treatment of B-cell non-Hodgkin's lymphoma.

Murine MAb to polymorphic epithelial mucin, human milk fat globule 1

Theragyn

Adjuvant treatment of ovarian cancer.

Mx-dnG1 or Rexin-G retroviral vector

REXIN-G

Treatment of pancreatic cancer For use in the diagnosis of invasive Mycobacterium avium disease in immunocompetent individuals.

Mycobacterium avium sensitin RS-10

Mycophenolate mofetil

Cellcept

Treatment of myasthenia gravis

Mycophenolate mofetil

CellCept

Treatment of pemphigus vulgaris

Myelin myo-inositol

Treatment sclerosis. Prevention of of multiple retinopathy of prematurity in preterm infants at risk for developing retinopathy of prematurity

myristoylated recombinant SCR1-3 of human APT070 complement reseptor type I

Prevention of delayed graft function in solid organ transplant

N-((methyl-diazacyclohexylmethylbenzamide)-asaphenylaminothiopyrrole) mesylate

Treatment of malignant gastrointestinal stromal tumors.

N-(2,3-dihydro-3,3-dimethyl-1H-indol-6-yl)-2[(4-pyridinylmethyl)amino]-3pyridinecarboxamide, phosphate (1:2)

Treatment of gastrointestinal stromal tumors

N-(2,4-Di-tert-butyl-5-hydroxyphenyl)-1,4dihydro-4-oxoquinoline-3-carboxamide

Treatment of patients with cystic fibrosis.

N-(2-amino-phenyl)-4-[(4-pyridin-3-ylpyrimidin-2-ylamino)-methyl] benzamide dihydrobromide

Treatment of Hodgkin's lymphoma

N-(methyl-diazacyclohexyl-methylbenzamide)azaphenyl-aminothiopyrrole) mesylate

Treatment of multiple myeloma.

N-[2-[(4-hydroxyphenyl)amino]-3-pyridinyl]-4methoxybenzenesulfonamide N-[3-(4',5'-bipyrimidin-2-ylamino)-4methylphenyl]-4-{[(3S)-3(dimethylamino)pyrrolidin-1-yl]methyl}-3(trifluoromethyl)benzamide

Treatment of neuroblastoma Treatment of Philadelphia chromosome-positive chronic myelogenous leukemia.

N-[4-(3-amino1H-indazol-4-yl)phenyl]-N1-(2fluoro-5-methylphenyl)urea

Treatment of hepatocellular carcinoma

N-[4-(4-amino-2-ethyl-1H-imidazo[4,5c]quinolin-1-yl)butyl]methanesulfonamide

Treatment of stages IIB-IV melanoma

N-[4-(4-amino-2-ethyl-lH-imidazo[4,5c]quinolin-1-yl)butyl]methanesulfonamide

Treatment of cutaneous T-cell lymphoma

N-[4-bromo-2-(1H-1,2,3,4-tetrazol-5yl)phenyl]-N'-[3,5bis(trifluoromethyl)phenyl]urea

Treatment of sickle cell disease

N-acetylcysteinate Lysine

Nacystelyn Dry Powder Inhaler For the management of cystic fibrosis

N-acetylcysteine N-acetylgalactosamine-4-sulfatase, recombinant human

Treatment of acute liver failure

Naglazyme

Treatment of mucopolysaccharidosis Type VI (Maroteaux-Lamy syndrome).

Napa

Treatment of adult Tay-Sachs disease To lower the defibrillation energy requirement sufficiently to allow automatic implantable cardioverter defibrillator therapy in those patients who could otherwise use the device. ventricular arrhythmias Preventionnot of life-threatening

N-acetyl-glucosamine thiazoline

N-acetylprocainamide N-acetyl-procainamide

in patients with documented procainamide-induced lupus.

N-acetyl-sarcosyl-glycyl-L-valyl-Dalloisoleucyl-L-threonyl-L-norvalyl-L-isoleucylL-arginyl_L-prolylethylaminde acetate

Treatment of soft tissue sarcoma

Nafarelin acetate

Synarel Nasal Solution Treatment of central precocious puberty.

Naltrexone HCl

Trexan

For blockade of the pharmacological effects of exogenously administered opioids as an adjunct to the maintenance of the opioid-free state in detoxified formerly opioid-dependent individuals.

Natural human lymphoblastoid interferonalpha

Treatment of polycythemia vera

Natural human lymphoblastoid interferonalpha

Treatment of Behcet's disease.

Natural human lymphoblastoid interferonalpha

Treatment of papillomavirus warts in the oral cavity of HIV positive patients.

NDROGE

Treatment of postanoxic intention myoclonus.

Nebacumab

Centoxin

Treatment of patients with gram-negative bacteremia which has progressed to endotoxin shock.

nelarabine

Arranon

Treatment of acute lymphoblastic leukemia and lymphoblastic lymphoma Treatment of motor neuron disease/amyotrophic lateral sclerosis.

Neurotrophin-1 NG-29

Somatrel

Diagnostic measure of the capacity of the pituitary gland to release growth hormone.

Nifedipine

Treatment of interstitial cystitis.

Nikkomycin Z

Treatment of coccidioidomycosis

nilotinib

Tasigna

Treatment of gastrointestinal stromal tumors.

Nilotinib

Treatment of chronic myelogenous leukemia

Nimotuzumab

Treatment of glioma

niprisan

Hemoxin

Treatment of sickle cell disease

nitazoxanide

Cryptaz

Treatment for intestinal amebiasis

nitazoxanide

Alinia

Treatment of intestinal giardiasis

Nitazoxanide

Alinia

Treatment of cryptosporidiosis.

Nitisinone

Orfadin

Treatment of alkaptonuria

Nitisinone

Orfadin

Treatment of tyrosinemia type 1.

Nitric oxide

Nitric oxide

Diagnosis of sarcoidosis

INOmax

To reduce the risk of chronic lung disease in premature neonates

Nitric oxide

INOmax

Treatment of persistent pulmonary hypertension in the newborn.

Nitric oxide

Treatment of acute respiratory distress syndrome in adults.

Nitroprusside

Treatment and prevention of cerebral vasospasm following hemorrhage. Treatmentsubarachnoid of follicular, medullary and anaplastic

N-Methyl-2-[3-[((E)-2-pyridin-2-yl-vinyl)-1Hindazol-6-ylsulfanyl]benzamide

Axitinib

thyroid carcinoma and metastatic or locally advanced papillary thyroid cancer.

Novel Acting Thrombolytic (NAT)

Treatment of peripheral arterial occlusion (PAO)

Nucleic acid aptamer binding to tumor cell nucleolin

Treatment of pancreatic cancer

Nucleic acid aptamer binding to tumor cell nucleon

Treatment of renal cell carcinoma

NZ-1002

Enzyme replacement therapy in patients with all subtypes of Mucopolysaccharidosis I.

Obatoclax mesylate

Treatment of chronic lymphocytic leukemia

Obatoclax mesylate

Treatment of myelodysplastic syndrome

Obatoclax mesylate

Treatment of myelofibrosis Treatment of advanced malignant melanoma (Stages II,III, IV).

oblimersen

Genasense

Octreotide

Sandostatin LARwith malignant carcinoid tumors.

Octreotide

Sandostatin LARTreatment of acromegaly.

Octreotide

Sandostatin LARintestinal peptide tumors (VIPoma).

Ofloxacin

Ocuflox Ophthalmic Solution Treatment of bacterial corneal ulcers.

Treatment of severe diarrhea and flushing associated

Treatment of diarrhea associated with vasoactive

oglufanide disodium

OM 401

Omacetaxine mepesuccinate

Treatment of ovarian cancer

Drepanol

Prophylactic treatment of sickle cell disease.

Treatment of chronic myelogenous leukemia

Omega-3 (n-3) polyunsaturated fatty acid with all double bonds in the cis configuration

Omega-3 (n-3) polyunsaturated fatty acids

Prevention of organ graft rejection.

Omacor

Oncorad Ov103

Oprelvekin

Treatment of ovarian cancer.

Neumega

oral unfractionated heparin

Prevention of severe chemotherapy-induced thrombocytopenia.

Treatment of sickle cell disease Treatment of familial amyotrophic lateral sclerosis associated with a mutation of the gene (on chromosome 21q) for copper, zinc superoxide dismutase.

Orgotein for injection

ortezomib

Treatment of IgA nephropathy.

Velcade

Treatment of multiple myeloma

Oxaliplatin

Treatment of ovarian cancer.

Oxalobacter formigenes

Treatment of primary hyperoxaluria

Oxandrolone

Oxandrin

Treatment of short stature associated with Turner's syndrome. Treatment of constitutional delay of growth and puberty.

Oxandrolone

Treatment of patients with Duchenne's muscular dystrophy and Becker's muscular dystrophy.

Oxandrolone

Oxandrin

Oxandrolone

Oxandrin

Oxandrolone

Hepandrin

Adjunctive therapy for AIDS patients suffering from HIV-wasting syndrome. Treatment of moderate/severe acute alcoholic hepatitis in the presence of moderate protein calorie malnutrition.

oxybate

Xyrem

Treatment of narcolepsy

oxybate

Oxymorphone

Xyrem

Treatment of narcolepsy. For relief of severe intractable pain in narcotic-tolerant

Numorphan H.P.patients.

Oxypurinol

Treatment of hyperuricemia in patients intolerant to allopurinol.

p1-(uridine 5'-)-p4-(2'-deoxycytidine 5'-) tetraphosphate, tetrasodium salt

For the treatment of cystic fibrosis

P1, P4-Di(uridine 5'-tetraphosphate), tetrasodium salt

Treatment of cystic fibrosis.

PA mAb

Abthrax

Treatment of anthrax

Paclitaxel

Taxol

Treatment of AIDS-related Kaposi's sarcoma.

Paclitaxel

Paxene

Treatment of AIDS-related Kaposi's sarcoma.

Paclitaxel (TOCOSOL)

Treatment of non-superficial urothelial cancer

Pafuramidine maleate

Treatment of human African trypanosomiasis (sleeping sickness)

Pafuramidine maleate

Treatment of malaria

pafuramidine maleate

Treatment of pneumocystis jiroveci pneuomina.

pancrelipase

VIOKASE

Treatment of steatorrhea associated with chronic pancreatitis.

panobinostat

Faridak

Treatment of cutaneous T-cell lymphoma

Papain, trypsin, and chymotrypsin

Wobe-Mugos

Treatment of multiple myeloma.

Papaverine topical gel

Treatment of sexual dysfunction in spinal cord injury patients.

parathyroid hormone

Treatment of hypoparathyroidism.

Parvovirus B19 (recombinant VP1 and VP2; S.frugiperda cells) vaccine

MEDI-491

Prevention of transient aplastic crisis in patients with sickle cell anemia. Treatment of patulous eustachian tube.

Patul-end

Patupilone

Treatment of ovarian cancer. For enzyme replacement therapy for ADA deficiency in patients with severe combined immunodeficiency.

Pegademase bovine

Adagen

Pegaspargase

Oncaspar

PEG-glucocerebrosidase

Lysodase

Treatment of acute lymphocytic leukemia. For use as chronic enzyme replacement therapy in patients with Gaucher's disease who are deficient in glucocerebrosidase.

Peginterferon alfa-2a

PEGASYS

Treatment of chronic myelogenous leukemia.

Peginterferon alfa-2a

PEGASYS

Treatment of renal cell carcinoma. Treatment of primary immunodeficiencies associated with T-cell defects.

PEG-interleukin-2

Pegvisomant

Somavert

Treatment of acromegaly.

Pegylated arginine deiminase

Melanocid

Treatment of invasive malignant melanoma.

Pegylated arginine deiminase Pegylated recombinant human megakaryocyte growth and development factor

Hepacid

Treatment of hepatocellular carcinoma. For reducing the period of thrombocytopenia in patients undergoing hematopoietic stem cell transplantation.

MEGAGEN

Peldesine

Treatment of cutaneous T-cell lymphoma.

pemetrexed disodium

Alimta

Treatment of malignant pleural mesothelioma

Pentamidine isethionate

Nebupent

Prevention of Pneumocystis carinii pneumonia in patients at high risk of developing this disease.

Pentamidine isethionate

Pentam 300

Treatment of Pneumocystis carinii pneumonia.

Pentamidine isethionate

Treatment of Pneumocystis carinii pneumonia.

Pentamidine isethionate (inhalation)

Pneumopent

Pentastarch

Pentaspan

Prevention of Pneumocystis carinii pneumonia in patients at highinrisk of developing this disease. As an adjunct leukapheresis to improve the

pentetate trisodium

harvesting and increase the yield of leukocytes by centrifugal means. Treatment of patients with known or suspected internal contamination with plutonium, americium, or diethylenetriaminepentaacetate curium.

Pentosan polysulfate sodium

Elmiron

Treatment of interstitial cystitis.

Pentostatin

Nipent

Treatment of patients with chronic lymphocytic leukemia.

Pentostatin

Nipent

Treatment of peripheral T-cell lymphomas.

Pentostatin

Nipent

Treatment of cutaneous T-cell lymphoma.

Pentostatin for injection

Nipent

Treatment of hairy cell leukemia.

Peptide 144 TGF beta-1 inhibitor

Treatment of systemic sclerosis

Peptide 144 TGF beta-1-inhibitor

Treatment of localized scleroderma

Peptidomimetic analog of hexarelin

Diagnosis of growth hormone deficiency

Perflubron

LiquiVent

Perfosfamide

Pergamid

Treatment of acute respiratory distress disease (ARDS) in adults For use in the ex-vivo treatment of autologous bone marrow and subsequent reinfusion in patients with acute myelogenous leukemia, also referred to as acute nonlymphocytic leukemia.

Pergolide

Permax

Treatment of Tourette's syndrome. For use as an adjunct to surgery, radiation therapy and chemotherapy for the treatment of patients with primary or recurrent malignant glioma.

Phenylacetate

Phenylalanine ammonia-lyase

Phenylase

Treatment of hyperphenylalaninemia.

Phenylbutyrate

Treatment of acute promyelocytic leukemia.

phenylephrine

Treatment of ileal pouch anal anastomosis related fecal incontinence

Phosphocysteamine

Treatment of cystinosis.

Pilocarpine

Salagen

Treatment of xerostomia induced by radiation therapy for head and neck cancer.

Pilocarpine HCl

Salagen

Treatment of xerostomia and keratoconjunctivitis sicca in Sjogren's syndrome patients.

Piracetam

Nootropil

Piritrexim isethionate

Treatment of myoclonus. Treatment of infections caused by Pneumocystis carinii, Toxoplasma gondii, and Mycobacterium avium-intracellulare.

Plasmid DNA vector expressing cystic fibrosis transmembrane gene

Treatment of cystic fibrosis

Plevitrexed

Plevitrexed

Treatment of ovarian cancer

Plevitrexed

Plevitrexed

Treatment of gastric (stomach) cancer

Plitidepsin

Aplidin

Treatment of acute lymphoblastic leukemia

Plitidepsin

Aplidin

Treatment of multiple myeloma

polifeprosan 20 with carmustine

Gliadel

Treatment of malignant glioma

Gliadel

Treatment of malignant glioma. Treatment of vasospasm in subarachnoid hemorrhage patients following surgical repair of a ruptured cerebral aneurysm.

Poloxamer 188

Flocor

Treatment of sickle cell crisis.

Poloxamer 188

Florcor

Treatment of severe burns requiring hospitalization.

Poloxamer 331

Protox

Initial therapy of toxoplasmosis in patients with AIDS.

Poly I: poly C12U

Ampligen

Treatment of renal cell carcinoma.

Poly I: poly C12U

Ampligen

Treatment of invasive metastatic melanoma (stage IIb, III, IV).

Poly I: poly C12U

Ampligen

Treatment of chronic fatigue syndrome.

Poly I: poly C12U

Ampligen

Treatment of AIDS.

polifeprosan 20 with carmustine Poloxamer 188

To control the clinical consequences of hyperuricemia in patients with severe gout in whom conventional therapy is contraindicated or has been ineffective.

Polyethylene glycol (PEG)-uricase

Polyethylene glycol-modified uricase

Zurase

Treatment of hyperuricemia in patients with gout refractory to conventional therapy or in whom conventional therapy is contraindicated Prophylaxis of hyperuricemia in cancer patients prone to develop tumor lysis syndrome during chemotherapy.

Polyethylene glycol-modified uricase

Zurase

Treatment of tumor lysis syndrome in cancer patients undergoing chemotherapy.

Poly-ICLC

Hiltonol

polyinosinic-polycytidilic acid

Poly-ICLC

Treatment of primary brain tumors. Treatment of flavivirus infections including those due to West Nile, Japanese encephalitis, dengue, St. Louis encephalitis, yellow fever, Murray valley, and Banzai viruses

polyinosinic-polycytidilic acid

Poly-ICLC

As an adjuvant to smallpox vaccination

polyinosinic-polycytidilic acid (Poly-ICLC)

Hiltonol

Treatment for orthopox virus infections

Polyethylene glycol-modified uricase

Polymeric oxygen

Treatment of sickle cell anemia.

Polyvalent, shed-antigen melanoma vaccine Porcine fetal neural dopaminergic cells and/or precursors aseptically prepared and coated with anti-MHC-1 Ab for intracerebral NeuroCell-PD implantation

Treatment of stage IIb to and stage IV melanoma Treatment of Hoehn and Yahr stage 4 and 5 Parkinson's disease.

Porcine fetal neural dopaminergic cells and/or precursors aseptically prepared for NeuroCell-PD intracerebral implantation. Porcine fetal neural gabaergic cells and/or precursors aseptically prepared and coated with anti-MHC-1 Ab for intracerebral NeuroCell-HD implantation Porcine fetal neural gabaergic cells and/or precursors aseptically prepared for intracerebral implantation for Huntington's NeuroCell-HD disease.

Treatment of Hoehn and Yahr stage 4 and 5 Parkinson's disease.

Treatment of Huntington's disease.

Treatment of Huntington's disease.

Porcine Sertoli cells aseptically prepared for intracerebral co-implantation with fetal neural tissue

N-Graft

porfimer

Photofrin

Esophagus in patients who are not considered to be candidates for esophagectomy

Porfimer sodium

Photofrin

Treatment of cholangiocarcinoma

Porfimer sodium

Photofrin

Porfimer sodium

Photofrin

For the photodynamic therapy of patients with primary or recurrent obstructing (either partially or completely) esophageal carcinoma. For the photodynamic therapy of patients with transitional cell carcinoma in situ of the urinary bladder.

Porfiromycin

Promycin

Treatment of cervical cancer.

Porfiromycin

Promycin

Treatment of head and neck cancer.

Posaconazole

Posoril

Treatment of zygomycosis

Potassium citrate

Urocit-K

For avoidance of the complication of calcium stone formation in patients with uric lithiasis.

Potassium citrate

Urocit-K

Prevention of calcium renal stones in patients with hypocitraturia.

Potassium citrate

Urocit-K

Prevention of uric acid nephrolithiasis. For the dissolution and control of uric acid and cysteine calculi in the urinary tract.

Potassium citrate and citric acid Potassium Iodide Oral Solution

Treatment of Hoehn and Yahr stage four and five Parkinson's disease. For the ablation of High-Grade Dysplasia in Barrett's

ThyroShield

For use as a thyroid blocking agent in pediatric patients exposed to radiactive iodine

potassium sodium aluminosilicate

For treatment of poisoning by or exposure to cesium.

PR1 Vaccine

Treatment of myelodysplastic syndromes (MDS) requiring therapy.

PR1 Vaccine

Treatment of acute myelogenous leukemia

PR1 Vaccine

Treatment of chronic myelogenous leukemia.

Pr-122 (redox-phenytoin)

For the emergency rescue treatment of status epilepticus, grand mal type.

PR-225 (redox-acyclovir)

Treatment of herpes simplex encephalitis in individuals afflicted with AIDS.

PR-239 (redox penicillin G)

Treatment of AIDS associated neurosyphilis.

Pr-320 (molecusol-carbamazepine)

For the emergency rescue treatment of status epilepticus, grand mal type.

Pralatrexate Pramiracetam Sulfate

Treatment of T-cell lymphoma For the management of cognitive dysfunction and enhancement of antidepressant activity associated with electroconvulsive therapy.

Praziquantel

Treatment of neurocysticercosis.

Sterecyt

Treatment of malignant non-Hodgkin's lymphomas. For use in combination with clindamycin hydrochloride in the treatment of Pneumocystis carinii pneumonia associated with AIDS.

Matulane

Treatment of malignant glioma of pregnancy in Establishment and maintenance women undergoing in vitro fertilization or embryo transfer procedures.

Propamidine isethionate 0.1% ophthalmic solution

Brolene

Treatment of acanthamoeba keratitis.

Prostaglandin E1 enol ester (AS-013)

Circulase

Treatment of Fontaine Stage IV chronic critical limb ischemia.

Prostaglandin E1 in lipid emulsion

Lipo-PGE1

Treatment of ischemic ulceration of the lower limbs due to peripheral arterial disease.

Protein C concentrate

Ceprotin

Treatment of ovarian cancer For replacement therapy in congenital protein C deficiency for the prevention and treatment of thrombosis, pulmonary emboli, and purpura fulminans.

Protein C concentrate

Protein C Concentrate (human) Vapor Heated, Immuno fulminans in meningococcemia.

Prednimustine Primaquine phosphate

Procarbazine HCl Progesterone

Protaxel

Protein C concentrate

For use in the prevention and treatment of purpura

For replacement therapy in patients with congenital or acquired protein C deficiency for the prevention and treatment of warfarin-induced skin necrosis during Protein C Concentrate (human) Vapor Heated, Immuno oral anticoagulation.

Protirelin

Prevention of infant respiratory distress syndrome associated with prematurity.

Protirelin injection

Treatment of amyothrophic lateral sclerosis.

Pulmonary surfactant replacement

Prevention and treatment of infant respiratory distress syndrome.

Pulmonary surfactant replacement, porcine

Curosurf

For the treatment and prevention of respiratory distress syndrome in premature infants.

Purified extract of Pseudomonas aeruginosa

ImmuDyn

Treatment of immune thrombocytopenia purpura where it is required to increase platelet counts.

Purified type II collagen

Colloral

Treatment of juvenile rheumatoid arthritis.

Pyruvate

Treatment of interstitial lung disease.

Quinacrine hydrochloride

For prevention of recurrence of pneumothorax in patients at high risk of recurrence.

quinine Sulfate

Treatment of malaria

R-(-)-gossypol

Treatment of chronic lymphocytic leukemia.

rAAV2-CB-hRPE65

Treatment of type II Leber's Congential Amaurosis

Induction treatment to prevent rejection and to minimize maintenance immunosupression in pediatric Rabbit anti-human thymocyte globulin (rATG) Thymoglobulin liver transplant recipients

Raloxifene

Evista

Reduction of the risk of breast cancer in postmenopausal women

Ranprinase

Onconase

Treatment for malignant mesothelioma

Rapamycin

Treatment of tuberous sclerosis complex

Rapamycin (mTOR) inhibitor

Treatment of bone sarcoma

rasburicase

Elitek

Treatment of malignancy-associated or chemotherapy-induced hyperuricemia.

recombinant adeno-associated virus alpha 1rAAV-AAT antitrypsin vector

Treatment of alpha1-antitrypsin deficiency

Recombinant anti-CD40 monoclonal antibody

Treatment of chronic lymphocytic leukemia

Recombinant anti-CD-40 monoclonal antibody

Treatment of multiple myeloma

Recombinant bactericidal/permeabilityincreasing protein

Neuprex

recombinant chimeric monoclonal antibody to Anthim anthrax

Treatment of severe meningococcal disease.

Treatment of exposure to B. anthracis spores

Recombinant coagulation factor VIIa

Novoseven

Treatment of diffuse alveolar hemorrhage

Recombinant deriative of C3 transferase

Cethrin

Recombinant Epstein-Barr virus gp350 glycoprotein vaccine recombinant fusion protein with a truncated form of the cytotoxic protein Pseudomonas exotoxin

Proxinium

Treatment spinal cord injury Prevention of of acute post-transplantation lymphoproliferative disorders in pediatric recipients of solid-organ transplantation Treatment of Ep-CAM-positive squamous cell carcinoma of the head and neck

Recombinant glycine2-human glucagon-like peptide-2

Recombinant human acid alpha-glucosidase

Treatment of short bowel syndrome.

Myozyme

Treatment of glycogen storage disease type II.

Recombinant human alpha 1-antitrypsin

Prevention of bronchopulmonary dysplasia

recombinant human alpha 1-antitrypsin (rAAT)

Treatment of cystic fibrosis

recombinant human alpha-1 antitrypsin

Treatment of cystic fibrosis.

recombinant human alpha-1 antitrypsin (rAAT)

To delay progression of chronic obstructive pulmonary disease resulting from AAT deficiency-mediated emphysema and bronchiectasis

Recombinant Human Alpha-Fetoprotein (rhAFP)

Treatment of myasthenia gravis

Recombinant human alpha-mannosidase

Treatment of alpha-mannosidosis

Recombinant human anti-GDF-8 (growth and differentiation factor-8) antibody

Treatment of Duchenne and Becker muscular dystrophies

Recombinant human antithrombin III

Treatment of antithrombin III dependent heparin resistance requiring anticoagulation.

Recombinant human C1 inhibitor

Treatment of capillary leakage syndrome

Recombinant human C1 inhibitor

Prevention and/or treatment of delayed graft function after solid organ transplantation Treatment of (acute attacks of) angioedema caused

Recombinant human C1-esterase inhibitor Recombinant human C1-esterase inhibitor

Recombinant human CD4 immunoglobulin G

by hereditary or acquired C1-esterase inhibitor deficiency. Prophylactic treatment of angioedema caused by hereditary or acquired C1-esterase inhibitor deficiency.

Recombinant human Clara Cell 10kDa protein

Treatment of AIDS resulting from infection with HIV-1. Prevention of neonatal bronchopulmonary dysplasia in premature neonates with respiratory distress syndrome.

recombinant human endostatin protein

Treatment of neuroendocrine tumors.

recombinant human endostatin protein

Treatment of metastatic melanoma

recombinant human fibroblast growth factor20

Treatment of radiation induced oral mucositis

Recombinant human gelsolin

Treatment of acute and chronic respiratory symptoms of bronchiectasis.

Treatment of the respiratory symptoms of cystic fibrosis.

Recombinant human gelsolin Recombinant human granulocyte colony stimulating factor Recombinant human highly phosphorylated acid alpha-glucosidase

TBD

Recombinant human insulin-like growth factor IGF-1 1 Recombinant human insulin-like growth factor IGF-1 1 Recombinant human insulin-like growth factor-I

PV802

Prevention of implantation failure For enzyme replacement therapy in patients with all subtypes of glycogen storage disease type II (GSDII, Pompe Disease)

Treatment hormone receptor Treatment of of growth antibody-mediated growthdeficiency. hormone resistance in patients with isolated growth hormone deficiency Ia. Treatment of short-bowel syndrome as a result of resection of the small bowel or as a result of congenital dysfunction of the intestines.

Recombinant human insulin-like growth factor-I

Treatment of post-poliomyelitis syndrome.

Recombinant human insulin-like growth factor-I/insulin-like growth factor binding protein-3

Treatment of major burns that require hospitalization.

Recombinant human interleukin-12

Treatment of renal cell carcinoma.

Recombinant Human Interleukin-21 (rIL-21)

Treatment of stage II (T4), III or IV malignant melanoma.

Recombinant human keratinocyte growth factor

Reducing the incidence and severity of radiationinduced xerostomia.

Recombinant human luteinizing hormone

For use in association with recombinant human follicle stimulating hormone for the treatment of women with chronic anovulation due to hypogonadotropic hypogonadism.

Luveris

Recombinant human lysosomal acid lipase or Cholestrase cholesteryl ester hydrolase

Treatment of lipase deficiencies, including Wolman Disease and cholesteryl ester storage disease

Recombinant human microplasmin

Treatment of peripheral arterial occlusion

recombinant human monoclonal antibody to hsp90

Mycograb

Treatment of invasive candidiasis

Recombinant human nerve growth factor

Treatment of HIV-associated sensory neuropathy.

recombinant human neutrophil inhibitor (hNE)

Treatment of cystic fibrosis

Recombinant human platelet derived growth factor BB

treatment of osteonecrosis of the jaws.

recombinant human porphobilinogen deaminase recombinant human porphobilinogen deaminase, erythropoetic form

Porphozyme

Treatment of acute intermittent porphyria attacks Treatment of acute intermittent porphyria preventing attacks

Recombinant human relaxin

Treatment of progressive systemic sclerosis.

Recombinant human thrombopoietin

For use in accelerating platelet recovery in patients undergoing hematopoietic stem cell transplantation.

Recombinant humanized MAb 5c8

Prevention of rejection of solid organ transplants.

Recombinant humanized MAb 5c8

Prevention of rejection of pancreatic islet cell transplants.

Recombinant humanized MAb 5c8

Prevention and treatment of Factor VIII/Factor IX inhibitors in patients with hemophilia A or B.

Recombinant humanized monclonal antibody 5c8

Treatment of immune thrombocytopenic purpura.

Recombinant humanized monoclonal antibody 5c8

Treatment of systemic lupus erythematosus.

recombinant inhibitor of human plasma kallikrein

Treatment of angioedema

Recombinant methionyl brain-derived neurotrophic factor

Treatment of amyotrophic lateral sclerosis.

recombinant ovine interferon tau

Tauferon

Recombinant Porcine Factor VIII, B-domain Deleted

Treatment pediatric multiple sclerosis Treatment of and prevention of episodic bleeding in patients with inhibitor antibodies to human coagulation factor VIII

Recombinant P-Selectin glycoprotein ligand

Prevention of delayed graft function in renal transplant patients

Recombinant P-selectin glycoprotein ligandimmunoglobulin Ig

Prevention of ischemia reperfusion injury in all solid organ transplants

Recombinant retroviral vector glucocerebrosidase

For use as enzyme replacement therapy for patients with types I, II, or III Gaucher disease.

Recombinant secretory leucocyte protease inhibitor

Treatment of cystic fibrosis.

Recombinant secretory leucocyte protease inhibitor

Treatment of congenital alpha-1 antitrypsin deficiency.

Recombinant soluble human CD4

Receptin

Treatment of acquired immunodeficiency syndrome.

Recombinant soluble human CD4 (rCD4)

Treatment of AIDS in patients infected with HIV virus.

Recombinant T-cell receptor ligand

Treatment of multiple sclerosis patients who are both HLA-DR2 positive and autoreactive to myelin oligodendrocyte glycoprotein residues 35-55

Recombinant truncated SPINT2 protease inhibitor

Treatment of cystic fibrosis

Recombinant urate oxidase

Prophylaxis of chemotherapy-induced hyperuricemia.

Reduced L-glutathione

Cachexon

Treatment of AIDS-associated cachexia.

Remacemide

Ecovia

Treatment of Huntington's disease. Prevention of delayed graft function in solid organ transplant

Reparixin

repository corticotropin or adrenocorticotropic H.P. Acthar Gel Treatment of infantile spasms hormone

resiniferatoxin Respiratory Syncytial Virus Immune Globulin (human)

Respiratory syncytial virus immune globulin (Human)

Treatment of intractable pain at end-stage disease Treatment of respiratory syncytial virus lower respiratory tract infections in hospitalized infants and Hypermune RSVyoung children.

Respigam

Prophylaxis of respiratory syncytial virus lower respiratory tract infections in infants and young children at high risk of RSV disease.

R-etodolac

Treatment of chronic lymphocytic leukemia

retroviral gamma-c cDNA containing vector

Treatment of X linked severe combined immune deficiency disease

Retroviral vector, R-GC and GC gene 1750

Treatment of Gaucher disease.

Reviparin sodium

Clivarine

Reviparin sodium

Clivarine

Treatment of deep vein thrombosis which may lead to pulmonary embolism in pediatric patients Long-term treatment of acute deep vein trombosis with or without pulmonary embolism in pregnant patients

SomatoKine

Treatment Treatment of of ovarian extremecancer. insulin resistance syndromes (type A, Rabson-Mendenhall syndrome, Leprechaunism, Type B syndrome)

RGG0853, E1A lipid complex rhIGF-I/rhIGFBP-3

rh-microplasmin

Adjunct to surgery in cases of pediatric vitrectomy

Rho (D) immune globulin intravenous (human) WinRho SD

Treatment of immune thrombocytopenic purpura.

Ribavirin

Virazole

Treatment of hemorrhagic fever with renal syndrome.

ribavirin

REBETOL

Treatment of chronic hepatitis C in pediatric patients

Ricin (blocked) conjugated murine mca (antib4)

For the ex-vivo purging of leukemic cells from the bone marrow of non-T cell acute lymphocytic leukemia patients who are in complete remission.

Ricin (blocked) conjugated murine MCA (antiB4)

Treatment of B-cell leukemia and B-cell lymphoma.

Ricin (blocked) conjugated murine MCA (antimy9)

Treatment of myeloid leukemia, including AML, and blast crisis of CML.

For use in the ex-vivo treatment of autologous bone marrow and subsequent reinfusion in patients with acute myelogenous leukemia.

Ricin (blocked) conjugated murine MCA (antimy9) Ricin (blocked) conjugated murine MCA (n901) Ricin (blocked) conjugated murine monoclonal antibody (CD6) Rifabutin

Mycobutin

Treatment cell lung cancer. Treatment of of small cutaneous T-cell lymphomas, acute Tcell leukemia-lymphoma, and related mature T-cell malignancies. Prevention of disseminated Mycobacterium avium complex disease in patients with advanced HIV infection.

Rifabutin

Treatment of disseminated Mycobacterium avium complex disease.

Rifalazil

Treatment of pulmonary tuberculosis. For antituberculosis treatment where use of the oral form of the drug is not feasible.

Rifampin

Rifadin I.V.

Rifampin, isoniazid, pyrazinamide

Rifater

Rifapentine

Priftin

For the short-course treatment of tuberculosis. Prophylactic treatment of Mycobacterium avium complex in patients with AIDS and a CD4+ count less than or equal to 75/mm3.

Rifapentine

Priftin

Treatment of Mycobacterium avium complex in patients with AIDS.

Rifapentine

Priftin

Treatment of pulmonary tuberculosis.

Rifaximin

Normix

Treatment of hepatic encephalopathy

RII retinamide

Treatment of myelodysplastic syndromes.

Riluzole

Rilutek

Treatment of Huntington's disease.

Riluzole

Rilutek

Treatment of amyotrophic lateral sclerosis.

risedronate sodium

Actonel

rituximab

Rituxan

Treatment of patients with osteogenesis imperfecta. Treatment of patients with anti-neutrophil cytoplasmic antibody-associated vasculitis (Wegener's Granulomatosis, Microscopic Polyangiitis, and ChurgStrauss Syndrome)

rituximab

Rituxan

Treatment of immune thrombocytopenic purpura

rituximab

Rituxan

Treatment of non-Hodgkin's B-cell lymphoma.

rituximab

Rituxan

Treatment of chronic lymphocytic leukemia

rofecoxib

VIOXX

Treatment of juvenile rheumatoid arthritis

rolespimycin hydrochloride

Treatment for gastrointestinal stromal tumor

romidepsin

Treatment of non-Hodgkin T-cell lymphomas To prolong time to relapse in leukemia patients who have undergone autologous bone marrow transplantation.

Roquinimex

Linomide

Rose Bengal Disodium

Treatment of metastatic melanoma

Venticute

Treatment of adult respiratory distress syndrome.

Venticute

rubitecan

For use in patients with pneumonia or aspiration of gastric contents leading to intubation, mechanical ventilation, and severe oxygen impairment Treatment of pediatric patients infected with human immunodeficiency virus and acquired immunodeficiency syndrome

Rufinamide

Treatment of Lennox-Gastaut Syndrome.

S(-)-3-[3-amino-phthalimido]-glutaramide

Treatment of multiple myeloma

rSP-C lung surfactant

rSP-C surfactant

Sacrosidase

Sucraid

Treatment of congenital sucrase-isomaltase deficiency.

S-adenosylmethionine

Treatment of AIDS-myelopathy.

salirasib

Leukine

Treatment of panreatic cancer. Treatment of neutropenia associated with bone marrow transplant, for the treatment of graft failure and delay of engraftment, and for the promotion of early engraftment.

Leukine

To reduce neutropenia and leukopenia and decrease the incidence of death due to infection in patients with acute myelogenous leukemia.

Sargramostim

Sargramostim

sarsasapogenin

Satumomab pendetide

Treatment of amyotrophic lateral sclerosis (ALS)

Oncoscint CR/OVDetection of ovarian carcinoma.

SB-408075

For pancreatic cancer

SC-1 monoclonal antibody

Treatment of patients with CD55 (sc-1) positive gastric tumors

SCH 58500

Treatment of primary ovarian cancer.

SDF-1 (108) Lysine Dlmer

Treatment of osteogenic sarcoma

Osteo-D

Treatment of familial hypophosphatemic rickets.

Selegiline HCl

Eldepryl

Treatment of bronchopulmonary dysplasia. As an adjuvant to levodopa and carbidopa treatment of idiopathic Parkinson's disease (paralysis agitans), postencephalitic Parkinsonism, and symptomatic Parkinsonism.

Sermorelin acetate

Geref

Sermorelin acetate

Geref

Treatment of idiopathic or organic growth hormone deficiency in children with growth failure. Adjunct to gonadotropin therapy in the induction of ovulation in women with anovulatory or oligo-ovulatory infertility who fail to ovulate in response to adequate treatment with clomiphene citrate alone and gonadotropin therapy alone.

Sermorelin acetate

Geref

Treatment of AIDS-associated catabolism/weight loss.

Serratia marcescens extract (polyribosomes)

Imuvert

Treatment of primary brain malignancies.

Secalciferol

Secretory leukocyte protease inhibitor

SGN-30 (anti-CD30 antibody)

Treatment of CD30 positive T-cell lymphomas

SGN-30 (anti-CD30 mAb)

Treatment of Hodgkin's disease

SGN-40 (anti-CD40 antibody)

Treatment of multiple myeloma.

Short chain fatty acid enema

Colomed

Treatment of chronic radiation proctitis.

Short chain fatty acid solution

Colomed

Treatment of the active phase of ulcerative colitis with involvement restricted to the left side of the colon.

Silver sulfadiazine and cerium nitrate

Flammacerium Prevention of mortality in severely burned patients.

siplizumab

Treatment of T-celloflymphomas For the treatment pulmonary arterial hypertensionin the absence of chronic obstructive pulmonary disease or congestive heart failure For the long term treatment of children who have growth failure due to a lack of adequate endogenous growth hormone secretion.

Sitaxsentan Sodium SK&F 110679

Sodium aluminosilicate Sodium ascorbate and menadione sodium bisulfite

Apatone

Treatment of chronic hepatic encephalopathy Treatment of metastatic or locally advanced inoperable transitional cell carcinoma of the urothelium (stage III and IV bladder cancer)

Sodium dichloroacetate

Treatment of homozygous familial hypercholesterolemia.

Sodium dichloroacetate

Treatment of congenital lactic acidosis.

Sodium dichloroacetate

Treatment of congenital lactic acidosis.

Sodium dichloroacetate

Treatment of lactic acidosis in patients with severe malaria.

sodium dichloroacetate

Use as an antidote in the management of systemic monochloroacetic acid poisoning

Sodium dichloroacetate

Ceresine

Sodium Monomercaptoundecahydro-closododecaborate

Borocell

Treatment of severe head injury.

Sodium monomercaptoundecahydro-closododecaborate

For use in boron neutron capture therapy (BNCT) in the treatment of glioblastoma multiforme. For use in conjunction with a thermal or epithermal neutron beam in boron nuclear capture therapy of glioblastoma multiforme.

Sodium nitrite

Treatment of vaso-occlusive crisis associated with sickle cell disease

Sodium nitrite

Treatment of cyanide poisoning

Sodium nitrite

Prevention of vasospasm associated with subarachnoid hemorrhage

Sodium nitrite/sodium thiosulfate

Cyanide AntidoteTreatment Packageof cyanide poisoning

Sodium phenylacetate/sodium benzoate 10%/10% Injection

Ammonul

Sodium phenylbutyrate

Sodium phenylbutyrate

Treatment of grade III and VI hepatic encephalopathy

Treatment of spinal muscular atrophy

Buphenyl

Treatment of spinal muscular atrophy

Sodium phenylbutyrate

For use as an adjuct to surgery, radiation therapy and chemotherapy for the treatment of patients with primary or recurrent malignant glioma.

sodium phenylbutyrate

Treatment of urea cycle disorders: carbamylphosphate synthetase deficiency, ornithine transcarbamylase deficiency, and arginiosuccinic acid synthetase deficiency.

Buphenyl

sodium phenylbutyrate

Treatment for sickling disorders, which include S-S hemoglobinopathy, S-C hemoglobinopathy, and Sthalassemia hemoglobinopathy.

Sodium pyruvate

Treatment of cystic fibrosis

Sodium stibogluconate

Treatment of cutaneous leishmaniasis

Sodium thiosulfate

Prevention of platinum-induced ototoxicity in pediatric patients

Sodium thiosulfate and sodium nitrite

Treatment of cyanide poisoning

Packageof cyanide poisoning Sodium thiosulfate, sodium nitrite, amyl nitrite Cyanide AntidoteTreatment

Solasonine and solamargine

Coramsine

Treatment of renal cell carcinoma

Solasonine and solamargine

Coramsine

Treaatment of high risk stage II, stage III and stage IV melanoma

Soluble complement receptor type 1

Prevention of post-cardiopulmonary bypass syndrome in children undergoing cardiopulmonary bypass.

Soluble recombinant human complement receptor type 1

Prevention or reduction of adult respiratory distress syndrome.

solvent/detergent treated non-blood group specific human coagulation active plasma

UNIPLAS

Somatostatin

Zecnil

Somatostatin

Treatment of thrombotic thrombocytopenic purpura Adjunct to the non-operative management of secreting cutaneous fistulas of the stomach, duodenum, small intestine (jejunum and ileum), or pancreas.

Treatment of bleeding esophageal varices. Treatment of short stature associated with Turner's syndrome. For long-term treatment of children who have growth

Somatrem for injection

Protropin

Somatrem for injection

Protropin

Somatropin

Humatrope

failure due to a lack of adequate endogenous growth hormone secretion. Treatment of short stature in pediatric patients with short stature homeobox-containing gene (SHOX) deficiency

Somatropin

Norditropin

Treatment of short stature in patients with Noonan syndrome

Somatropin

Norditropin

Treatment of short stature associated with Turner's syndrome.

Somatropin

Humatrope

Somatropin

Norditropin

Treatment of short stature associated with Turner syndrome. Adjunct for the induction of ovulation in women with infertility due to hypogonadotropic hypogonadism or bilateral tubal occlusion or unexplained infertility, who are undergoing in vivo or in vitro fertilization procedures.

Somatropin

Biotropin

Treatment of cachexia associated with AIDS.

Somatropin

Genotropin

Treatment of adults with growth hormone deficiency.

Somatropin

Serostim

Treatment of patients with HIV-associated adipose redistribution syndrome

Somatropin

Nutropin

For use in the long-term treatment of children who have growth failure due to a lack of adequate endogenous growth hormone secretion.

Somatropin (rDNA)

Saizen

For the enhancement of nitrogen retention in hospitalized patients suffering from severe burns.

Somatropin (rDNA origin)

Saizen

Treatment of idiopathic or organic growth hormone deficiency in children with growth failure.

Somatropin (rDNA origin)

Long-term treatment of children who have growth failure due to a lack of adequate endogenous growth Nutropin Depot hormone secretion.

Somatropin (rDNA origin) injection

Norditropin

Treatment of growth failure in children due to inadequate growth hormone secretion.

Somatropin (r-DNA)

Zorbtive

For use alone or in combination with glutamine in the treatment of short bowel syndrome.

Somatropin (r-DNA) for injection

Serostim

Treatment of children with AIDS-associated failure-tothrive including AIDS-associated wasting.

Somatropin [rDNA]

Genotropin

Treatment of short stature in patients with Prader-Willi syndrome.

somatropin [rDNA]

Genotropin

Somatropin for injection

Humatrope

Treatment of growth failure in children who were born small for gestational age. For the long-term treatment of children who have growth failure due to inadequate secretion of normal endogenous growth hormone.

Somatropin for injection

Nutropin

As replacement therapy for growth hormone deficiency in adults after epiphyseal closure.

Somatropin for injection

Nutropin

Treatment of growth retardation associated with chronic renal failure.

Somatropin for injection

Serostim

Treatment of AIDS-associated catabolism/weight loss.

Somatropin for injection

Nutropin

Treatment of short stature associated with Turner's syndrome.

Sorafenib

Nexavar

Treatment of hepatocellular carcinoma

Sorafenib

Nexavar

Treatment of stage IIB through stage IV melanoma

Sorafenib

Nexavar

Treatment of renal cell carcinoma.

Sorivudine

BRAVAVIR

Treatment of herpes zoster (shingles) in immunocompromised patients.

Sotalol HCl

Betapace

Prevention of life threatening ventricular tachyarrhythmias.

Sotalol HCl

Betapace

Treatment of life-threatening ventricular tachyarrhythmias.

Spiramycin

Rovamycine

For symptomatic relief and parasitic cure of chronic cryptosporidiosis in patients with immunodeficiency.

squalamine lactate

Treatment of ovarian cancer refractory or resistant to standard chemotherapy

SS1(dsFv)-PE38

Treatment of epithelial ovarian cancer

SS1(dsFv)-PE38

Treatment of malignant mesothelioma

ST1-RTA immunotoxin (SR 44163)

Treatment of patients with B-chronic lymphocytic leukemia.

Prevention of acute graft versus host disease in allogenic bone marrow transplantation.

ST1-RTA immunotoxin (SR 44163) Staphylococcus aureus Immune Globulin (Human)

Altastaph

Stem and progenitor cells derived from ex vivo expanded allogeneic umbilical cord blood StemEx

Prophylaxis against Staphylococcus aureus infections in low birth weight neonates For use as hematopoietic support in patients with relasped or refractory hematologic malignancies who are receiving high-dose therapy

Sterile talc

Steritalc

Treatment of malignant pleural effusion.

Sterile talc

Steritalc

Treatment of pneumothorax.

Sterile talc powder

Sclerosol Intrapleural Aerosol Treatment of malignant pleural effusion.

SU101

Treatment of ovarian cancer.

SU101

Treatment of malignant glioma.

Succimer

Chemet

Succimer

Chemet

Succimer

Chemet capsulesTreatment of lead poisoning in children.

Treatment of mercury intoxication. Prevention of cystine kidney stone formation in patients with homozygous cystinuria who are prone to stone development.

Sucralfate

Treatment of oral mucositis and stomatitis following radiation therapy for head and neck cancer.

Sucralfate suspension

Treatment of oral complications of chemotherapy in bone marrow transplant patients.

Sucralfate suspension

Treatment of oral ulcerations and dysphagia in patients with epidermolysis bullosa.

Sulfadiazine

For use in combination with pyrimethamine for the treatment of Toxoplasma gondii encephalitis in patients with and without AIDS.

Sulfapyridine

Treatment of dermatitis herpetiformis. For protection of donor organ tissue from damage or injury mediated by oxygen-derived free radicals that are generated during the necessary periods of ischemia (hypoxia, anoxia), and especially reperfusion, associated with the operative procedure.

Superoxide dismutase (human)

Superoxide dismutase (recombinant human)

Oxsodrol

Prevention of reperfusion injury to donor organ tissue.

Suramin

Metaret

Treatment of hormone-refractory prostate cancer.

Surface active extract of saline lavage of bovine lungs

Infasurf

Treatment and prevention of respiratory failure due to pulmonary surfactant deficiency in preterm infants.

Surfactant (human) (amniotic fluid derived)

Human Surf

Prevention and treatment of neonatal respiratory distress syndrome.

Synsorb Pk

Treatment of verocytotoxogenic E. coli infections. For use in conjunction with diagnostic procedures (including ERCP) for pancreatic disorders to increase pancreatic fluid secretion

Synthetic human secretin

Synthetic human secretin

For use in the diagnosis of gastrinoma associated with Zollinger-Ellison syndrome. For use in conjunction with diagnostic procedures for pancreatic disorders to increase pancreatic fluid secretion.

Synthetic human secretin

For use in obtaining desquamated pancreatic cells for cytopathologic examination in pancreatic carcinoma.

Synthetic human secretin

For use in the evaluation of exocrine pancreas function.

Synthetic human secretin Synthetic porcine secretin

For use in obtaining desquamated pancreatic cells for cytopathologic examination in pancreatic carcinoma.

Synthetic porcine secretin

For use in the evaluation of exocrine pancreas function.

Synthetic porcine secretin

For use in conjunction with diagnostic procedures for pancreatic disorders to increase pancreatic fluid secretion.

Synthetic porcine secretin

For use in the diagnosis of gastrinoma associated with Zollinger-Ellison syndrome.

T4 endonuclease V, liposome encapsulated

To prevent cutaneous neoplasms and other skin abnormalities in xeroderma pigmentosum.

Tacrolimus

Prograf

Prophylaxis of organ rejection in patients receiving heart transplants.

Tacrolimus

Prograf

Prophylaxis of graft-versus-host-disease.

Tadalafil

Cialis

Treatment of pulmonary arterial hypertension

TAK-603

Treatment of Crohn's disease.

talactoferrin alfa

Treatment of non-small cell lung cancer

talactoferrin alfa

Treatment of renal cell carcinoma

talactoferrin alfa

For the treatment of graft versus host disease

talactoferrin alfa

For the prevention of graft-versus-host disease

Talotrexin

Treatment of acute lymphoblastic leukemia

T-cell depleted stem cell enriched cellular product from peripheal b lood stem cells

Treatment of chronic granulomatous disease

TD-K6a.513a.12

ReveKer

Technetium Tc 99m pterotetramide

Treatment of pachyonychia congenita

For the identification of ovarian carcinomas.

Technetium Tc99m anti-melanoma murine monoclonal antibody

Oncotrac Melanoma Imaging Kit malignant melanoma.

For use in detecting, by imaging, metastases of

Technetium Tc99m murine monoclonal antibody (IgG2a) to B cell

LymphoScan

Technetium Tc99m murine monoclonal antibody to hCG

Immuraid, hCG-Tc-99m and trophoblastic cell tumors.

Technetium Tc99m murine monoclonal antibody to human AFP

AFP-Scan

Technetium Tc99m murine monoclonal antibody to human alpha-fetoprotein

Immuraid, AFP-Scan hepatoblastoma.

Technetium Tc99m rh-Annexin V

Apomate

Diagnostic imaging in the evaluation of the extent of disease in patients with histologically confirmed diagnosis of non-Hodgkin's B-cell lymphoma, acute Bcell lymphoblastic leukemia (in children and adults), and chronic B-cell lymphocytic leukemia. Detection of hCG producing tumors such as germ cell

Detection of alpha-fetoprotein producing germ cell tumors. Detection of hepatocellular carcinoma and

Tegafur/gimeracil/oteracil

Diagnosis or assessment of rejection status in heart, heart-lung, single lung, or bilateral lung transplants.

Treatment of gastric cancer

temocillin sodium

Negaban

Temoporfin

Foscan

Treatment of pulmonary infections caused by Burkholderia cepacia Palliative treatment of recurrent, refractory or second primary squamous cell carcinomas of the head and neck in patients considered to be incurable with surgery or radiotherapy.

temozolomide

Temodar

Treatment of malignant glioma

Temozolomide

Temodal

Treatment of newly diagnosed high grade glioma

Temozolomide

Temodal

Treatment of advanced metastatic melanoma.

Temozolomide

Temodar

Treatment of recurrent malignant glioma.

Temsirolimus

Torisel

Treatment of renal cell carcinoma

Teniposide

Vumon for injection leukemia.

Teriparatide

Parathar

Diagnostic agent to assist in establishing the diagnosis in patients presenting with clinical and laboratory evidence of hypocalcemia due to either hypoparathyroidism or pseudohypoparathyroidism.

Teriparatide

Parathar

Treatment of idiopathic osteoporosis.

Treatment of refractory childhood acute lymphocytic

Terlipressin

Glypressin

Terlipressin (INN)

Treatment of bleeding esophageal varices.

Treatment of Hepatorenal Syndrome Treatment of weight loss in AIDS patients with HIVassociated wasting. testosterone replacement in For use as physiologic

Testosterone

Androgel

Testosterone

TheraDerm Testosterone Transdermal System weight loss.

androgen deficient HIV+ patients with an associated

Testosterone propionate ointment 2%

Treatment of vulvar dystrophies.

Testosterone sublingual

Treatment of constitutional delay of growth and puberty in boys.

Tetrabenazine

Xenazine

Tetrabenazine

Tetrahydrobiopterin

Treatment of Huntington's disease.

Treatment of moderate/severe tardive dyskinesia.

Phenoptin

Tetraiodothyroacetic acid

Treatment of of hyperphenylalaninemia Suppression thyroid stimulating hormone in patients with well-differentiated cancer of the thyroid gland.

Tezacitabine

Treatment of adenocarcinoma of the esophagus and stomach

TGF(beta)2-specific phosphorothioate antisense oligodeoxynucleotide

Oncomun

TGp1PTH1-34

Treatment of malignant glioma

Treatment of solitary (unicameral) bone cysts.

Thalomid

Treatment Myelodysplastic Syndrome Treatment of and prevention of recurrent aphthous ulcers in severely, terminally immunocompromised patients.

Thalidomide

Synovir

Treatment of HIV-associated wasting syndrome.

Thalidomide

Thalomid

Treatment of Crohn's disease.

Thalidomide Thalidomide

Thalidomide

Prevention of graft versus host disease in patients receiving bone marrow transplantation.

Thalidomide

Treatment of graft versus host disease in patients receiving bone marrow transplantation.

Thalidomide

Treatment and maintenance of reactional lepromatous leprosy.

Thalidomide

Treatment of the clinical manifestations of mycobacterial infection caused by Mycobacterium tuberculosis and non-tuberculous mycobacteria.

Thalidomide

Prevention of graft versus host disease.

Thalidomide

Treatment of graft versus host disease.

Thalidomide

Treatment of primary brain malignancies.

Thalidomide

Treatment of severe recurrent aphthous stomatitis in severely, terminally immunocompromised patients.

Thalidomide

Thalomid

Thalidomide

Treatment of erythema nodosum leprosum.

Treatment of Kaposi's sarcoma.

Thalidomide

Thalomid

Treatment of multiple myeloma

Thiotepa

Tepadina

Conditioning treatment prior to hematopoietic stem cell transplantation

Thymalfasin

Zadaxin

Treatment of stage IIb through Stage IV malignant melanoma

Thymalfasin

Zadaxin

Treatment of chronic active hepatitis B.

Thymalfasin

Zadaxin

Treatment of DiGeorge anomaly with immune defects.

Thymalfasin

Zadaxin

Treatment of hepatocellular carcinoma.

Thymosin beta 4

Treatment of epidermolysis bullosa Reversal of phenylephrine-induced mydriasis in patients who have narrow anterior angles and are at risk of developing an acute attack of angle-closure glaucoma following mydriasis.

Thymoxamine HCl Thyrotropin alfa

Thyrogen

Treatment of well-differentiated papillary, follicular or combined papillary/follicular carcinomas of the thyroid

Thyrotropin alpha

Thyrogen

As an adjunct in the diagnosis of thyroid cancer.

Tiapride

Treatment of Tourette's syndrome.

Tiazofurin (2-Beta-D-ribofuranosyl-4thiazolecarboxamide)

Chronic myelogenous leukemia (CML)

Tilarginine acetate

Treatment of cardiogenic shock

tin ethyl etiopurpurin

Prevention of access graft disease in hemodialysis patients

tinidazole

Tindamax

Treatment of giardiasis

Tinidazole

Tindamax

Treatment of amebiasis

Tiopronin

Thiola

Prevention of cystine nephrolithiasis in patients with homozygous cystinuria.

Tipifarnib

Zarnestra

Treatment of acute myeloid leukemia

Triacana

Treatment of head and neck cancer For use in combination with levo-thyroxine to suppress thyroid stimulating hormone in patients with well-differentiated thyroid cancer who are intolerant to adequate doses of levo-thyroxine alone.

tirapazamine

Tiratricol Tissue repair cells obtained from autologous bone marrow expanded ex vivo with a cell production system

Treatment of osteonecrosis

Tissue repair cells obtained from autologous bone marrow expanded ex vivo with a cell production system

Treatment of dilated cardiomyopathy

Titanium dioxide and bisoctrizole

For the secondary prevention (prevention of lesional induction) of disorders with UV-A and visible lightinduced photosensitivity, specifically Actinic prurigo, Hydroa vacciniforme, Solar urticara (SU), Chronic Actinic Dermatitis (CAD), the cutaneous prop

Tizanidine HCl

Zanaflex

Treatment of spasticity associated with multiple sclerosis and spinal cord injury.

Tobramycin

Tobi

Treatment of bronchiectasis patients infected with Pseudomonas aeruginosa.

Tobramycin for inhalation

TOBI

Tocophersolan oral solution (vitamin E-tpgs)

Topiramate

Topamax

Treatment of bronchopulmonary infections of Pseudomonas aeruginosa in cystic fibrosis patients. Treatment of vitamin E deficiency resulting from malabsorption due to prolonged cholestatic hepatobiliary disease.

Treatment of Lennox-Gastaut syndrome.

toralizumab

Treatment of immune thrombocytopenic purpura

Toremifene

Treatment of desmoid tumors.

Toremifene

Fareston

Hormonal therapy of metastatic carcinoma of the breast.

Tositumomab and iodine I 131 tositumomab

Bexxar

Treatment of non-Hodgkin's B-cell lymphoma.

trabectedin

Yondelis

Treatment of soft tissue sarcoma.

trabectedin

Yondelis

Treatment of patients with epithelial ovarian cancer

Tramadol hydrochloride

Management of postherpetic neuralgia

Tramadol hydrochloride

Cyklokapron

Treatment of painful HIV-associated neuropathy Treatment of patients with congenital coagulopathies who are undergoing surgical procedures (e.g. dental extractions).

Tranexamic acid

Cyklokapron

Treatment of patients undergoing prostatectomy where there is hemorrhage or risk of hemorrhage as a result of increased fibrinolysis or fibrinogenolysis.

Tranexamic acid

Cyklokapron

Treatment of hereditary angioneurotic edema.

Tranilast

Rizaben

For the treatment of maligant glioma

Tranexamic acid

Transforming growth factor-beta 2

Treatment of full thickness macular holes.

Transgenic human alpha 1 antitrypsin

Treatment of emphysema secondary to alpha 1 antitrypsin deficiency.

Trastuzumab

Herceptin

Treatment of patients with pancreatic cancer that overexpress p185HER2.

Treosulfan

Ovastat

Treatment of ovarian cancer.

treprostinil

Remodulin

Treatment of pulmonary arterial hypertension.

Tretinoin

Vesanoid

Treatment of acute promyelocytic leukemia.

Tretinoin

ATRA-IV

Treatment of acute and chronic leukemia.

Tretinoin

ATRA-IV

Treatment of T-cell non-Hodgkin's lymphoma Treatment of squamous metaplasia of the ocular surface epithelia (conjunctiva and/or cornea) with mucous deficiency and keratinization.

Tretinoin tri-antennary glycotripeptide derivative of 5fluorodeoxyuridine monophosphate

Treatment for hepatocellular carcinoma Treatment of patients with Wilson's disease who are intolerant, or inadequately responsive to penicillamine.

Trientine HCl

Syprine

Triheptanoin

Triheptanoim-SASOl Special Oil acid disorders Treatment of fatty

Trimetrexate

Neutrexin

Trimetrexate glucuronate

Treatment of metastatic osteogenic sarcoma. Treatment of patients with advanced non-small cell carcinoma of the lung.

Trimetrexate glucuronate

Neutrexin

Treatment of Pneumocystis carinii pneumonia in AIDS patients.

Trimetrexate glucuronate

Treatment of pancreatic adenocarcinoma.

Trimetrexate glucuronate

Treatment of metastatic colorectal adenocarcinoma.

Trimetrexate glucuronate

Treatment of metastatic carcinoma of the head and neck (i.e. buccal cavity, pharynx, and larynx). For use in the palliative treatment of advanced

Triptorelin pamoate

Decapeptyl Injection ovarian carcinoma of epithelial origin.

Trisaccharides A and B

Biosynject

Trisaccharides A and B

Biosynject

Trisaccharides A and B

Treatment of moderate to severe clinical forms of hemolytic disease of the newborn arising from placental transfer of antibodies against blood group substances A and B. Prevention of ABO medical hemolytic reactions arising from ABO-incompatible bone marrow transplantation. Treatment of moderate to very severe clinical forms of transfusion reactions arising from ABO incompatible transfusions of blood, blood products, and blood derivatives. For use in ABO-incompatible solid organ

Trisaccharides A and B

Biosynject

transplantation, including kidney, heart, liver and pancreas.

Trisodium citrate concentration

Hemocitrate

For use in leukapheresis procedures. Treatment of patients with known or suspected internal contamination with plutonium, americium, or curium to increase the rate of elimination.

Trisodium zinc Diethylenetriaminepentaacetate

Troxacitabine

Troxatyl

Trypan blue

MembraneBlue ophthalmic surgical victrectomy procedures Treatment of symptomatic patients with AIDS

Selectively staining epiretinal membranes during including all patients with CD4 counts less than 200 cells per mm3. Treatment of symptomatic patients with the AIDS including all patients with CD4 T-cell counts less than 200 cells per mm3.

Tumor necrosis factor-binding protein 1 Tumor necrosis factor-binding protein II

Tyloxapol

Treatment of acute myeloid leukemia

Supervent

tyrosine kinase inhibitor

Treatment of cystic fibrosis.

Treatment of mastocytosis

Ubiquinol

Ubi-Q-Nol, Li-Q-Nol Treatment of Huntington's Disease

Ubiquinol, coenzyme Q10, ubiquinone

UBI-Q-NOL

Treatment of pediatric congestive heart failure

Ubiquinone

Ubi-Q-Gel

Treatment of mitochondrial cytopathies.

Unconjugated Chimeric (human-murine) G250 IgG monoclonal antibody

Treatment of renal cell carcinoma.

Urea for intravitreal injection

Neurosolve

Treatment of retinitis pigmentosa To facilitate the removal of lung secretions in the treatment of patients with primary ciliary dyskinesia.

Uridine 5'-triphosphate

Uridine 5'-triphosphate

Urofollitropin

Metrodin

Urofollitropin

Fertinex

Treatment of cystic fibrosis. For induction of ovulation in patients with polycystic ovarian disease who have an elevated LH/FSH ratio and who have failed to respond to adequate clomiphene citrate therapy. For the initiation and re-initiation of spermatogenesis in adult males with reproductive failure due to hypothalamic or pituitary dysfunction, hypogonadotropic For acceleration ofhypogonadism. corneal epithelial regeneration and healing of stromal incisions from corneal transplant surgery.

Urogastrone Ursodiol

Actigall

Management of the clinical signs and symptoms associated with primary biliary cirrhosis.

Ursodiol

URSO

Treatment of patients with primary biliary cirrhosis.

Vaccinia Immune Globulin (Human) Intravenous

CNJ-016

Treatment of complications of vaccinia vaccination

Vaccinia Immune Globulin (Human) Intravenous

Valine, isoleucine and leucine

Treatment of severe complications from the smallpox vaccine

VIL

Treatment of hyperphenylalaninemia. Treatment of primary keratoconjunctivitis and recurrent epithelial keratitis due to HSV1 and HSV2.

valine-valine-ganciclovir

Valproic acid, sodium

PEAC

Treatment of familial adenomatous polyposis

Valrubicin

Valstar

Vandetanib

Zactima

Treatment of carcinoma in situ of the urinary bladder. Treatment of patients with follicular thyroid carcinoma, medullary thyroid carcinoma, anaplastic thyroid carcinoma, and locally advanced and metastatic papillary thyroid carcinoma

Vapreotide

Sanvar

Treatment of symptomatic carcinoid tumors

vapreotide

Sanvar

Treatment of esophageal variceal hemorrhage patients with portal hypertension.

vapreotide

Octastatin

Treatment of gastrointestinal and pancreatic fistulas.

vapreotide

Octastatin

Prevention of early postoperative complications following pancreatic resection.

vapreotide

Sanvar

Varicella Zoster Immune Globulin (Human)

VariZIG

For the treatment of acromegaly Passive immunization for the treatment of exposed, susceptible individuals who are at risk of complications from varicella

Vasoactive intestinal peptide

Treatment of Acute Respiratory Distress Syndrome.

Vasoactive Intestinal Peptide

Treatment of pulmonary arterial hypertension

Vasoactive intestinal polypeptide

Treatment of acute esophageal food impaction.

Vibriolysin

Vibrilase

Debridement of severe, deep dermal burns in hospitalized patients

vigabatrin

Sabril

Treatment of infantile spasms.

Viloxazine HCl

Catatrol

Treatment of narcolepsy.

Viloxazine HCl

Catatrol

Treatment of cataplexy.

vincristine sulfate liposome injection

Marqibo

Treatment of acute lymphoblastic leukemia.

Virulizin

Virulizin

Treatment of pancreatic cancer.

viscous budesonide

Treatment for pediatric eosinophilic esophagitis.

vorinostat

Treatment of multiple myeloma

vorinostat

Zolinza

vorinostat

Xenogeneic hepatocytes

Treatment of T-cell non-Hodgkin's lymphoma

Treatment of mesothelioma

HepatAssist LiverTreatment Assist System of severe liver failure.

Yttrium (90Y) antiferritin polyclonal antibodies Ferritarg P

Treatment of Hodgkin's disease.

Yttrium-90 radiolabeled humanized monoclonal anti-carcinoembroyonic antigen IgG antibody

Treatment of ovarian carcinoma.

Cea-Cide

Zalcitabine

Hivid

Zalcitabine

Treatment of AIDS.

Treatment of AIDS.

Zidovudine

Retrovir

Treatment of AIDS.

Zidovudine

Retrovir

Treatment of AIDS related complex.

Zinc acetate

Galzin

Treatment of Wilson's disease.

Zoledronate

Zometa, Zabel Treatment of tumor induced hypercalcemia.

Zosuquidar trihydrochloride

Treatment of acute myeloid leukemia

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PharmAthene, Inc.

3/31/2003

Intarcia Therapeutics, Inc.

1/10/2005

Tibotec, Inc.

8/10/2004

BioCryst Pharmaceuticals, Inc.

8/13/2004

BioCryst Pharmaceuticals, Inc.

1/29/2004

BioCryst Pharmaceuticals, Inc.

1/10/2005

Fujisawa Healthcare, Inc.

9/1/2004

PTC Therapeutics

1/10/2005

PTC Therapeutics, Inc.

7/5/2007

Global Alliance for TB Drug Development

8/19/2003

Pfizer Global Research and Development

11/29/2002

Novartis Pharmaceuticals Corporation

8/13/2004

Adventrx Pharmaceuticals, Inc.

12/8/2004

Inotek Pharmaceuticals Corporation

7/12/2007

Otsuka Pharmaceutical Company, Ltd

10/3/2001

Phase 2 Discovery, Inc.

7/3/2003

Phase 2 Discovery, Inc.

3/28/2006

Auris Medical, Inc.

11/4/2003

Aeolus Pharmaceuticals, Inc.

7/10/2003

Genzyme Corporation

10/21/2004

Vion Pharmaceuticals, Inc.

5/12/1998

Oxford GlycoSciences

6/10/1999

Louisiana State University Medical Center Foundation

2/10/1999

NeoRx Corporation

1/25/2007

Adeza Biomedical

9/9/2004

Kosan Biosciences, Inc

9/3/2004

Kosan Biosciences, Inc.

2/25/2004

Amicus Therapeutics, Inc.

6/18/2007

Amicus Therapeutics, Inc

5/23/2006

FoldRx Pharmaceuticals, Inc.

12/2/2003

Callisto Pharmaceuticals, Inc.

9/18/2006

Callisto Pharmaceuticals, Inc.

1/13/2003

Repligen Corporation

8/15/2003

Inologic, Inc.

9/17/1993

Kennedy & Hoidal, M.D.'s

12/10/2004

Rexahn Corporation

12/8/2004

Rexahn Corporation

12/8/2004

Rexahn Corporation

12/1/2004

Rexahn Corporation

12/1/2004

Rexahn Corporation

7/21/1987

National Cancer Institute, Dct

2/27/1987

Lemmon Company

8/3/2001

Lawrence Panasci, MD

11/15/2001

Pangene Corporation

9/9/1996

Grant, Steven M.D.

4/11/2005

PR Pharmaceuticals, Inc.

4/4/2005

EntreMed, Inc.

6/16/2006

EntreMed, Inc.

7/10/2001

EntreMed, Inc.

11/18/2005

Prosena B.V.

3/23/2000

Sugen, Inc.

9/11/1998

Sugen, Inc.

12/18/1990

Jacobus Pharmaceutical Company

9/20/2000

Elliot Danforth, Jr., M.D.

11/20/1989

Berlex Laboratories, Inc.

10/11/2006

Dynogen Pharmaceuticals, Inc.

12/12/2005

A. Carlsson Research AB

4/10/2003

Kiadis Pharma Canada, Inc.

12/21/1998

Biomedical Frontiers, Inc.

8/22/2007

Metabasis Therapeutics, Incorporated

12/14/2005

Neurorecovery, Inc.

4/26/2006

Jacobus Pharmaceutical Co., Inc.

12/13/1989

Beeken, Warren M.D.

12/1/2005

Trophos SA

7/20/2006

Johnson & Johnson Pharmaceutical Research & Dev,

12/27/2006

SIGA Technologies, Inc.

12/18/2006

SIGA Technologies, Inc.

6/15/2007

ClinTec International Ltd.

10/11/2006

Reata Pharmaceuticals, Inc.

8/20/2003

Now Pharm AG

5/11/1992

ILEX Oncology, Inc.

6/18/2007

Humanetics, Inc.

9/2/1999

GlaxoSmithKline

12/20/1993

Biogen, Inc.

8/3/1987

SuperGen, Inc.

5/26/2006

Xechem International, Inc.

5/26/2006

Hana Biosciences, Inc.

3/5/2004

InterMune, Inc.

2/6/2006

Cornerstone Pharmaceuticals, Inc.

Treatment of pediatric HIVinfection/AIDS patients

4/6/1999

MGI Pharma, Inc.

3/24/1997

SciClone Pharmaceuticals, Inc.

6/22/1993

Therakos, Inc.

5/12/1994

Therakos, Inc.

1/29/2004

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for treatment of patients with myelodysplastic syndromes (MDS) including previously treated and untreated, de novo and secondary MDS of all French-American-British subtypes Treatment(refractory of chronicanemia, iron refractory anemia with ringed overload due to blood sideroblasts, refractory anemia transfusions (transfusional hemosiderosis) in patients 2 years of age or older

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Reduction in signs and symptoms of moderately to severely active polyarticularcourse juvenile rheumatoid arthritis in patients who have had an inadequate response to one or more disease-modifying anti-rheumatic drugs.

Treatment of advanced breast cancer in postmenopausal women whose disease has progressed following tamoxifen therapy.

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Immunex Corporation

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Hollander, Eric MD

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For the induction of spermatogenesis in men with primary and secondary hypogonadotropic hypogonadism in whom the cause of infertility is not due to 12/21/1998 primary testicular failure. Use for suspected or confirmed methanol poisoning, either alone or in combination with 12/22/1988 hemodialysis As an antidote to ethylene glycol (antifreeze) poisoning, or for use in suspected ethylene glycol 12/22/1988 ingestion.

For the control of generalized convulsive status epilepticus.

Serono Laboratories, Inc.

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Questcor Pharmaceuticals, Inc.

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Biocraft Laboratories, Inc.

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Bausch & Lomb Surgical, Chiron Vision Products

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6/5/2001 Treatment of short bowel syndrome in patients receiving specialized nutritional support 8/19/2003 when used in conjunction with a rercombinant human growth hormone that is approved for 3/6/1995 this indication.

Teva Pharmaceuticals USA

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Schering Corporation

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Schering Corporation

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Schering Corporation

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Schering Corporation

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Valeant Pharmaceuticals International

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Novartis Pharmaceuticals Corporation

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Bristol-Myers Squibb Pharmaceutical Research Institute

Treatment of adults who can 9/21/2000 tolerate oral medication and who have mild to moderate malaria caused by Plasmodium falciparum or Plasmodium vivax. 11/4/1991

Alexion Pharmaceuticals, Inc.

SmithKline Beecham Pharmaceuticals

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Collgard Biopharmaceuticals Ltd.

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Cadila Pharmaceuticals Limited, Inc.

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Orphan Europe

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Abbott Laboratories

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Indevus Pharmaceuticals (Formerly Valera Pharma.) Anderson, Karl E., M.D.

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Bristol-Myers Squibb Pharmaceutical Research Institute

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11/25/2003 For use as a single daily exchange for the long (8-16 hour) dwell during continuous 5/5/2004 ambulatory peritoneal dialysis (CAPD) or automated peritoneal dialysis (APD) for the management of chronic renal 7/18/1997 failure.

SmithKlineBeecham Corporation

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Farmacon-IL, LLC

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Jerini AG

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Baxter Healthcare Corporation

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Pharmacia & Upjohn

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Santhera Pharmaceuticals Limited

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Indicated for patients with Hunter syndrome (mucopolysaccharidosis II, MPS II). Idursulfase has been shown to improve walking capacity in In combination these patients with certain other 11/28/2001 approved antineoplastic agents, for third line chemotherapy in the treatment of germ cell 1/20/1987 testicular cancer.

Bristol-Myers Squibb Pharmaceutical Research Institute

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Treatment of pulmonary arterial hypertension (WHO Group I) in patients with NYHA Class III or 8/17/2004 IV symptoms

Treatment of patients with chronic myeloid leukemia (CML) in blast crisis, accelerated phase, or in chronic phase after failure of interferonTreatment of adult patients with alpha therapy aggressive mastocytosis (ASM) without the D816V c-Kit mutation Treatment adult patients with or with c-Kitofmutational status myelodysplastic/myeloproliferati unknown ve diseases (MDS/MPD) associated with PDGFR Treatment of adult patients with (platelet-derived growth factor hypereosinophic syndrome receptor) genechronic re-arrangements (HES) and/or eosinophilic leukemia (CEL) who have the FIP1L1-PDGFRα fusion kinase (mutational analysis or FISH demonstration of CHIC2 allele deletion) and for Treatment of HES adult and/or patients with patients with CEL relapsed or refractory Philadelphia chromosome positive acute lymphoblastic leukemia (Ph+ALL) Treatment of adult patients with unresectable, recurrent and/or metastatic dermatofibrosarcoma Treatment of(DFSP) patients with Kit protuberans (CD117) positive unresectable and/or metastatic malignant gastrointestinal stromal tumors (GIST)

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Bayer Corporation

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Treatment of chronic myelogenous leukemia.

Treatment of selected patients with AIDS-related Kaposi's sarcoma.

Centocor, Inc.

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Hoffmann-La Roche, Inc.

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Schering Corporation

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Schering Corporation

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Schering Corporation

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Schering Corporation

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Schering Corporation

6/22/1987

Schering Corporation

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Schering Corporation

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Treatment of relapsing forms of multiple sclerosis to slow the 3/11/1996 accumulation of physical disability and decrease the frequency of clinical 12/16/1991 exacerbations.

In ambulatory patients with relapsing-remitting multiple sclerosis to reduce the frequency of clinical exacerbations.

Serono Laboratories, Inc.

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Adjunctive diagnostic agent in the localization of primary or metastatic pheochromocytomas. 11/14/1984

University of Michigan

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Brogan Pharmaceuticals, LLC

Treatment of patients with known or suspected internal contamination with radioactive cesium and/or radioactive or non-radioactive thallium to increase their rates of elimination

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Treatment of advanced renal Induction therapy in patients cell carcinoma with refractory childhood acute lymphoblastic leukemia when used in combination with other approved anticancer agents.

Biolitec Pharma Ireland Ltd.

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2/27/1998 Acute treatment of the cutaneous manifestations of moderate to severe erythema 5/1/1995 nodosum leprosum (ENL) and as maintenance therapy for prevention and suppression of the cutaneous manifestations of 7/26/1995 ENL recurrences.

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For the acute and intermittent management of increased muscle tone associated with spasticity.

Management of cystic fibrosis patients with P.aeruginosa.

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Treatment of metastatic breast Treatment of patients with CD20 cancer in postmenopausal positive, follicular, non-positive or women with estrogen Hodgkin's lymphoma, with and 9/19/1991 receptor unknown tumors. without transformation, whose disease is refractory to Rituximab and has relapsed 5/16/1994 following chemotherapy

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Cangene Corporation

Treatment and modification of aberrant infections induced by vaccinia virus that include its accidental implantation in eyes (except in cases of isolated keratitis), mouth, or other areas where vaccinia infection would constitute a special hazard; 6/18/2004 eczema

DynPort Vaccine Company LLC

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For maintenance treatment of patients with Wilson's disease who have been initially treated with a chelating agent.

Treatment of hypercalcemia of malignancy.

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Sponsor Address

Text4

Text34

One Park Place

Suite 450

Annapolis MD 21401

2000 Powell Street

Suite 1640

Emeryville CA 94608

1020 Stony Hill Road

Yardley PA 19067

2190 Parkway Lake Drive

Birmingham AL 35244

2190 Parkway Lake Drive

Birmingham AL 35244

2190 Parkway Lake Drive

Birmingham AL 35244

Three Parkway North

Deerfield IL 60015-2548

100 Corporate Court

South Plainfield NJ 07080

100 Corporate Court

South Plainfield NJ 07080

80 Broad Street

New York NY 10004

50 Pequot Avenue

New London CT 06320

One Health Plaza

Building 105

East Hanover NJ 07936-1080

6725 Mesa Ridge Road

Suite 100

San Diego CA 92121

100 Cummings Center

Beverly MA 01915

2440 Research Blvd

Rockville MD 20850

3130 Highland Avenue, Third Floor

Cincinnati OH 45219-2374

3130 Highland Ave.

Third Floor

211 East Ontario Street

Chicago IL 60611

PO Box 14287; 79 T.W. Alexander Dr.

4401 Research

500 Kendall Street

Cambridge MA 02142

Cincinnati OH 45219

Research Triangle Park NC 27709

Text56

Four Science Park

New Haven CT 06511

10, The Quadrant

Abington Science Park

United Kingdom

1600 Canal St.

10th Floor

New Orleans LA 70112

410 W. Harrison Street

Seattle WA 98119-4007

1240 Elko Drive

Sunnyvale CA 94089

3832 Bay Center Place

Hayward CA 94545

3832 Bay Center Place

Hayward CA 94545

6 Cedar Brook Drive

Cranbury NJ 08512

6 Cedar Brook Drive

Cranbury NJ 08512

300 Technology Square

Cambridge MA 02139

2 Executive Drive

Suite 450

420 Lexington Avenue

New York NY 10170

41 Seyon Street

Building 1, Suite 100

101 Elliott Ave., West

Seattle WA 98119

University of Utah Health Sciences Center

50 North Medical Drive, Room 4R240

9620 Medical center Drive

Rockville MD 20850

9620 Medical Center Drive

Rockville MD 20850

9620 Medical center Drive

Rockville MD 20850

9620 Medical Center Drive

Rockville MD 20850

Somerset NJ 08873

Waltham MA 02453

Salt Lake City UT 84132

9620 Medical Center Drive

Rockville MD 20850

NIH, Exec. Plaza N., Room 7-18

Bethesda MD 20892

1510 Delp Drive

Kulpsville PA 19443

Professor of Medicine, McGill University 3755 Cote Ste Catherine

5500 Stewart Avenue

Fremont CA 94538

Massey Cancer Center, VCU

P.O. Box 980230

1716 Heath Parkway

Fort Collins CO 80524

9640 Medical Center Drive

Rockville MD 20850

9640 Medical Center Drive

Rockville MD 20850

9640 Medical Center Drive

Rockville MD 20850

Montreal, Quebec H3T 1E2

Richmond VA 232980230

Einsteinweg 55

230 East Grand Ave.

South San Francisco CA 94080

230 East Grand Ave.

South San Francisco CA 94080-4811

37 Cleveland Avenue

P.O. Box 5290

Princeton NJ 08540

University of Vermont

84 Beartown Road

Underhill VT 05489

1401 Harbor Bay Parkway

Alameda CA 94501

52 Second Avenue

Waltham MA 02451

Joakim Tedroff, M.D.

S-412 46 Goteborg

2525 Marie-Curie

Saint-Laurent (Quebec) H4S 2E1

1095 10th Ave., S.E.

Minneapolis MN 55414

11119 North Torrey Pines Road

LaJolla CA 92037

Crescent Center

Suite 930

37 Cleveland Lane

Princeton NJ 08540

University Of Vermont

Given C-317

Memphis TN 38119

Burlington VT 05405

Parc scientifique de Lumigny, Case 931 1322 Marseille cedex

920 U S Highway 202

P.O. Box 300

Raritan NJ 08869

4575 SW Research Way

Corvallis OR 97333

4575 SW Research Way

Corvallis OR 97333

1055 Westlakes Drive

Berwyn PA 19312

1950 N. Stemmons Freeway

Dallas TX 75207-3199

241, route d'Arlon

L-1150

4545 Horizon Hill Blvd.

San Antonio TX 78229-2263

10400 Viking Drive

Eden Prairie MN 55344

Five Moore Dr.

P.O. Box 13398

14 Cambridge Center

Cambridge MA 02142

4140 Dublin Blvd.

Suite 200

Dublin CA 94568

New Brunswick Technoloogy Center

Building 1, Suite 310

New Brunswick NJ 08901-3279

7000 Shoreline Court

Suite 370

South San Francisco CA 94080

3280 Bayshore Blvd

Brisbane CA 94005

25 Health Science Drive

Stony Brook NY 11790

Research Triangle Park NC 27709-3398

Bloomington MN 55437-3107

5775 West Old Shakopee

Suite 100

901 Mariner's Island Boulevard

San Mateo CA 94404-1593

Oaklands Corporate Center

437 Creamery Way

Exton PA 19341

Oaklands Corporate Center

437 Creamery Way

Exton PA 19341

300 American Road

Morris Plains NJ 07950

2525 Dupont Drive

P.O. Box 19534

Irvine CA 92623-9534

4140 Dublin Blvd.

Suite 200

Dublin CA 94568

P.O. Box 900

Germantown MD 20875-0900

7 Powder Horn Drive

9432 Old Katy Road

Houston TX 77055

6455 Nancy Ridge Dr.

San Diego CA 92121

Via Tito Speri 10

Pomezia Roma

P.O. Box 4500

Princeton NJ 08543-4500

209 10th Street South

Suite 332

500 Kendall Street

Cambridge MA 02142

P.O. Box 1128

Decatur IL 62525

200 Abbott Park Road

Abbott Park IL 60064-6188

200 Abbott Park Road

Abbott Park IL 60064-6157

P. O. Box 22506 1301 Harbor Bay Parkway

Alameda CA 94502

Warren NJ 07059

Nashville TN 37203

38009

1301 Harbor Bay Parkway

Alameda CA 94502

11801 Research Drive

Alachua FL 32615

11801 Research Drive

Alachua FL 32615

1100 Olive Way, Suite 100

Seattle WA 98101

8455 Beverly Boulevard

Suite 308

160 Paulson Road

Waban MA 02468

10835 Altman Row

Suite 150

San Diego CA 92121

6 Warren Mews

London W1T6AR

London

718 Bradford Avenue

Westfield NJ 07090

3333 Vacaville Parkway

Suite 1000

300 Technology Square

Cambridge MA 02139

128 Spring Street

Lexington MA 02173

One Franklin Plaza

P.O. Box 7929

Philadelphia PA 19101

35227

One Franklin Plaza

P.O. Box 7929

Philadelphia PA 19101

35227

3 Pine View Road

Mount Kisco NY 10549

4560 Horton Street

Emeryville CA 94608-2916

4560 Horton Street

Emeryville CA 94608-2916

33729

4560 Horton Street

Emeryville CA 94608-2916

35804

4560 Horton St.

Emeryville CA 94608-2916

Los Angeles CA 90048

Vacaville CA 95688

37018

4545 Horizon Hill Blvd.

San Antonio TX 78229-2263

126 East Lincoln Ave.

Rahway NJ 07065-0900

Division of Human Genetics

Children's Hospital Research Foundation

146 Medinah Drive

Blue Bell PA 19422-3212

146 Medinah Drive

Blue Bell PA 19422-3212

One Kendall Square

Cambridge MA 02139-1562

One Kendall Square

Cambridge MA 02139-1562

33333

55 Challenger Road

Ridgefield Park NJ 07660

36193

10275 Science Center Dr.

San Diego CA 92121-1117

2301 Highway 60 East

Lake Crystal MN 56055

Post Office Box 1000

50 Division Street, Suite 503

14132 E. Firestone Boulevard

Santa Fe Springs CA 90670

6 Blackstone Valley Place

Lincoln RI 02865

Via Olgettina 58

Milan 20132

3030 Cornwallis Road

P.O. Box 12700

Research Triangle Park NC 27709

3030 Cornwallis Road

P.O. Box 12700

Research Triangle Park NC 27709

PO Box 1887

Greenville NC 27835-1887

Cincinnati OH 452293039

Montville NJ 070451000

35202

3030 Cornwallis Road

Research Triangle Pk NC 27709

Dagger Lane, Elstree, Hertfordshire

WD6 3BX

Dagger Lane

Elstree, Hertfordshire

4560 Horton Street

Emeryville CA 94608-2916

Kiryat Weizmann

Kiryat Weizmann 1020 First Ave.

PO Box 61501

King of Prussia PA 19406-0901

Pharmaceutical Division, Biological Products

400 Morgan Lane

New Haven CT 06516 32113

The Mount Sinai School Of Medicine

Fifth Avenue at 100th Street, Box 1203

New York NY 10029

Department of Chemistry

Convent Avenue & 138th Street

New York NY 10031

700 Main Street

Cambridge MA 02139

National Institutes of Health, 31 Center Drive MSC

Building 31, Room 9N-222

Bethesda MD 208922560

39 Old Ridgebury Road

Suite 11

Danbury CT 06810

P.O. Box 2038

Milwaukee WI 53201

Johns Hopkins University

600 N. Wolfe St., Jefferson 1-109

Baltimore MD 21287

One Tower Bridge

100 Front Street, Suite 400

Conshohocken PA 19428

33233

55 Corporate Drive

Bridgewater NJ 08807

7575 West 103rd Avenue

Suite 102

Westminister CO 80021-5426

39248

One Amgen Center Drive

Thousand Oaks CA 91320-1799

One MedImmune Way

Gaithersburg MD 20878

One MedImmune Way

Gaithersburg MD 20878

One MedImmune Way

Gaithersburg MD 20878

One Tower Bridge

100 Front Street, Suite 400

West Conshohocken PA 19428

35041

Conshohocken PA 19428

One Tower Bridge

100 Front Street, Suite 400

One MedImmune Way

Gaithersburg MD 20878

11 Deer Park Drive

Monmouth Junction NJ 08852-1923

5 Moore Drive

PO Box 13398

Research Triangle Park NC 27709

Department of Ophthalomology

880 Kempsville Road, Suite 2500

Norfolk VA 235023990

25 Upton Drive

Wilmington MA 01887

66 Hanover Road

Florham Park NJ 07932

37 Cleveland Lane

P.O. Box 5290

580 California Street

San Francisco CA 94104

University of Illinois at Chicago College of Pharm

833 South Wood Street (m/c886) Rm. 176 Chicago IL 60612

Princeton NJ 08540

36335

34515

University Of Illinois At Chicago College of Pharm 833 South Wood Street (m/c886) Rm. 176 Chicago IL 60612 University of Illinois at Chicago College of Pharm

833 South Wood Street (m/c886) Rm. 176 Chicago IL 60612

21 N. Skokie Valley Highway

Suite G3

P.O. Box 8299

Philadelphia PA 19101

3930 Varsity Drive

Ann Arbor MI 48108

300 Technology Square

Cambridge MA 02139

150 Industrial Road

San Carlos CA 94070-6256

One Research Way

Princeton NJ 08540

One Research Way

Princeton NJ 08540

Lake Bluff IL 60044

34914

One Research Way

Princeton NJ 08540

One Research Way

Princeton NJ 08540

One Research Way

Princeton NJ 08540

One Research Way

Princeton NJ 08540

Parke-Davis Pharmaceutical Research Division

2800 Plymouth Road

2500 Millbrook Drive

Buffalo Grove IL 60089

Meridian Center II

4 Industrial Way West

Eatontown NJ 077242274

Meridian Center III

6 Industrial Way West

Eatontown NJ 07724

Meridian Center II

4 Industrial Way West

Eatontown NJ 077242274

One Kendall Square

Cambridge MA 02139

2450 Bayshore Parkway

Mountain View CA 94043

2450 Bayshore Parkway

Mountain View CA 94043

400 South El Camino Real

Suite 1200

3000 Continental Dr., North

Mt. Olive NJ 07828

4041 MacArthur Boulevard, Suite 375

Newport Beach CA 92660

4041 MacArthur Blvd.

Suite 375

2910 Seventh Street

Berkeley CA 94710

2910 Seventh Street

Berkeley CA 94710

Dr. Claude Hariton

Chief Medical Officer, VP, Cli

Quebec G1P 4P5, Canada

5200 Research Place

San Diego CA 92122

21823 30th Drive Southeast

Bothell WA 98021

35356

Ann Arbor MI 48106

San Mateo CA 944021703

Newport Beach CA 92660

35503

1620 Waukegan Road

Mcgaw Park IL 60085

957 Buckingham Avenue

Berkshire SL1 4NL

345 North Smith Avenue

St. Paul MN 55102

345 North Smith Avenue

St. Paul MN 55102

345 North Smith Avenue

St. Paul MN 55102

345 North Smith Avenue

St. Paul MN 55102

50 Pequot Avenue

New London CT 06320

700 Children's Drive

Columbus OH 43205

5555 Valley Boulevard

Los Angeles CA 90032-3548

P. O. Box 8299

Philadelphia PA 19101-8299

1884 Miles Avenue

Elkhart IN 46515

1020 First Avenue

PO Box 61501

King Of Prussia PA 19406-0901

6355 Topanga Canyon Blvd.

Suite 510

Woodland Hills CA 91367

2910 Seventh Street

Berkeley CA 94710

2910 Seventh Street

Berkeley CA 94710

4905 23rd Avenue North

Minneapolis MN 55447

2 Meridan Road

M9W 4Z7

2 Meridan Road

M9W427

1896 Rutherford ?Road

Carlbad CA 92008

39113

34025

36251

2910 Seventh Street

Berkeley CA 94710

9900 Corporate Campus Drive

Suite 3000

Lindhagensgatan 133

SE-112 87

Pharmaceutical Division, Biological Products

400 Morgan Lane

New Haven CT 06516 33602

1020 First Ave.

PO Box 61501

King of Prussia PA 19406-0901

9312 Old Georgetown Road

Bethesda MD 20814

500 Kendall Street

Cambridge MA 02142

1600 Hayes Street

Nashville TN 37203

1101 Kermit Drive,

Suite 608

1207 17th Ave. S., Suite 103

Nashville TN 37212

5445 East Cheryl Parkway

Madison WI 53711

26 Landsdowne St.

Cambridge MA 02139-4234

211 Bailey Rd.

West Henrietta NY 14586-9728

Frankland Road

Swindon SN5 8RU

Wiltshire

1110 Lake Cook Rd.

Suite 257

Buffalo Grove IL 60089

Oakdene Court

Winnersh, Berkshire RG41 5UA

50 Undine Road

Newton MA 02135

Pharmaceutical Division

400 Morgan Lane

300 American Road

Morris Plains NJ 07950

130 Waverly Street

Cambridge MA 02139-4242

Louisville KY 40223

32855

Nashville TN 37217

36801

38097

West Haven CT 06516

34332

Boston University

Cancer Research Center

Boston MA 02118

11726 San Vicente Blvd.

Los Angeles CA 90049

University of Cincinnati School of Medicine/

P. O. Box 670669

41 Moores Road

Frazer PA 19355

41 Moores Road

Frazer PA 19355

41 Moores Road

Frazer PA 19355

201 Elliott Ave. West

Suite 400

41 Moores Road

Frazer PA 19355

41 Moores Road

Frazer PA 19355

41 Moores Road

Frazer PA 19355

41 Moores Road

P.O. Box 4011

Frazer PA 19355

Bldg 405/4051

One Health Plaza

East Hanover NJ 07936-1080

Office of the Surgeon General

622 Neiman Street

Ft. Detrick MD 217029240

Special Programme for Research and Training in Tro

Via Appia , Geneva 27

783 Jersey Avenue

New Brunswick NJ 08901

2921 W. McArthur Blvd.

Santa Ana CA 92704-6929

Lilly Corporate Center

Indianapolis IN 46285

5 Moore Drive

PO Box 13398

5 Moore Drive

Research Triangle Park NC 27709

Cincinnati OH 45267231 Albert Sabin Way 0559

Seattle WA 98119

Research Triangle Park NC 27709

36794

36165

33933

5 Moore Drive

PO Box 13398

Research Triangle Park NC 27709

5 Moore Drive

PO Box 13398

Research Triangle Park NC 27709-3398

8060 Reeder Street

Lenexa KS 66214-1554

Two Connell Drive

Berkeley Heights NJ 07922

Two Connell Drive

Berkeley Heights NJ 07922

Two Connell Drive

Berkeley Heights NJ 07922

3005 First Avenue

Seattle WA 98121

1946 Young Street

Honolulu HI 96826

22322 20th Avenue SE

Suite 150

Bothell WA 98021

9200 Indian Creek Parkway

Building 9, Suite 200

Overland Park KS 66210

2029 Century Park East

Sixth Floor

Los Angeles CA 90067

7000 SW 97th Avenue

Miami FL 33173

3 Forbes Rd.

Lexington MA 02421

3 Forbes Rd.

l MA 02421

600 College Road East

CN 5308

La Jolla Laboratories

San Diego CA 92121

2525 28th Street

Boulder CO 80301

787 Seventh Ave., 48th Floor

New York NY 10019

2025 First Ave.

Suite 800

P. O. Box 970

Pacific Palisades CA 90272

Princeton NJ 085405308

38126

Seattle WA 98121

One Executive Drive

P.O. Box 1399

800 53rd Avenue N.E.

Minneapolis MN 55432

1400 Providence Highway

Norwood MA 02062

800 53rd Avenue N.E.

P.O. 1250

710 Medtronic Parkway NE

Minneapolis MN 55432-5604

1700 Perimeter Park Drive

Morrisville NC 27560

39071

59 Route 10

East Hanover NJ 07936-1080

35927

A Subsidiary of DOR BioPharma, Inc.

850 Bear Tavern Road

Ewing NJ 08628

A Subsidiary of DOR BioPharma, Inc.

850 Bear Tavern Road

Ewing NJ 08628

41 Moores Road

Frazer PA 19355

2525 McGaw Avenue

P.O. Box 19791

8125 N. Hayden Road

Scottsdale AZ 85258

677 W. Dekalb Pike

King of Prussia PA 19406

70 Grand Avenue

River Edge NJ 07661

836 Farmington Avenue

Suite 207

625 Cleveland Avenue

Columbus OH 43215

625 Cleveland Avenue

Columbus OH 43215

33420

625 Cleveland Avenue

Columbus OH 43215

33420

68 T.W. Alexander Drive, PO Box 14186 Research Triangle Park NC 27709

Bldg. 337, Paint Branch Drive

College Park MD 20742

Fort Lee NJ 07024

33780

Minneapolis MN 55440-9087

Irvine CA 92623

32134

38400

West Hanford CT 06119-1551

Bldg. 337, Paint Branch Drive

College Park MD 20742

3180 Porter Drive

Palo Alto CA 94304

8455 Beverly Blvd.

Suite 308

Los Angeles CA 90048

8455 Beverly Blvd.

Suite 308

Los Angeles CA 90048

1440 Davey Road

Woodridge IL 60517

1 DNA Way

South San Francisco CA 94080-4990

1 DNA Way

South San Francisco CA 94080-4990

1 DNA Way, MS #242

South San Francisco CA 94080-4990

1 DNA Way

South San Francisco CA 94080-4990

55 Challenger Road

Ridgefield Park NJ 07660

Guardwell, Kinsale

County Cork

70 Grand Avenue

Suite 109

River Edge NJ 07661

Suite 235

7200 Hudson Blvd.

Oakdale MN 55128

14 Emmett Place

Whitby, Ontario L1R 2B4

7000 SW 97th Avenue

Miami FL 33173

Ion Channel Advances

PO Box 14487

One MedImmune Way

Gaithersburg MD 20878

8 Campus Drive

Parsippany NJ 07054

11199 Sorrento Valley Rd.

San Diego CA 92121-1334

35363

36523

38924

Durham NC 27709

35115

P.O. Box 4000

Princeton NJ 08543

5 Research Parkway

Wallingford CT 06492

40 Landsdowne Street

Canbridge MA 02139

1840 Gateway Dr.

2nd Floor

1 Bath Rd., Maidenhead

Berkshire SL6 4UH

1 Bath Road

Maidenhead

1155 15th Street, N.W., #315

Washington DC 20005

2525 Dupont Drive

P.O. Box 19534

1261 Furnace Brook Parkway

Quincy MA 02169

2525 Dupont Drive

P.O. Box 19534

Irvine CA 92623-9534 36881

2525 Dupont Drive

P.O. Box 19534

Irvine CA 92713

32871

2525 Dupont Drive

P.O. Box 19534

Irvine CA 92713

32871

800 Gateway Blvd.

South San Francisco CA 94080

27 Maple Street

Milford MA 01757-3650

27 Maple Street

Milford MA 01757-3650

2151 Berkeley Way

Berkeley CA 94704-1011

1030 North Parkview Drive

Bismarck ND 58501

4001 Lexington Avenue North

Arden Hills MN 55126

540 Arapeen Drive, Suite 202

Salt Lake City UT 84108

One Gustave L. Levy Place

New York NY 10029

2525 Dupont Dr.

P.O. Box 19534

38436

San Mateo CA 94404 37215

Berkshire, SL6 4UH

Irvine CA 92623-9534

36868

37917

Irvine CA 92623-9534

1950 Lake Park Drive

Smyra GA 30080

900 Ridgebury Road, Box 368

Ridgefield CT 06877-0368

225 East Deerpath, Suite 250

Lake Forest IL 60045

610 Lincoln Street

Waltham MA 02451

12419 198th Drive, NE

Woodinville WA 98072

1120 Win Drive

Bethlehem PA 18017

1901 Huguenot Road

Richmond VA 23235

37537

1901 Huguenot Road

Richmond VA 23235

37537

34801 Campus Drive

Fremont CA 94555

36195

111 Rock Road

Horsham PA 19044-2310

4140 Dublin Boulevard

Dublin CA 94568

4140 Dublin Blvd

Suite 200

Two Annabel Lane, Suite 220

San Ramon CA 94583

Childrens Hospital of Los Angeles MS 55

Los Angeles CA 90027

Childrens Hospital of Los Angeles

4650 Sunset Blvd, MS 55

1550 East Gude Drive

Rockville MD 20850

1550 East Gude Drive

Rockville MD 20850

3030 Cornwallis Road

P.O. Box 12700

236 Old Lancaster Road

Merion Station PA 19066

5555 Valley Boulevard

Los Angeles CA 90032

1020 First Ave.

PO Box 61501

One Baxter Way

Westlake Village CA 91362

35335

Dublin CA 94568

Los Angeles CA 90027

Research Triangle Pk NC 27709

King of Prussia PA 19406-0901

Hyland Division (Baxter Hyland)

550 North Brand Blvd.

21823 30th Drive Southeast

Bothell WA 98021

1501 Wakarusa Drive

Lawrence KS 66047

59 Route 10

East Hanover NJ 07936

59 Route 10

East Hanover NJ 07936

60 Columbian Street

P.O. Box 361

28101 Ballard Road, Suite F

Lake Forest IL 60045

4204 Glencoe Avenue

Marina Del Rey CA 90292

190 Commerce Drive

Warwick RI 02886

145 Sakonnet Blvd.

Narragansett RI 02882

3940 Quebec Avenue North

Minneapolis MN 55427

1576 Sweet Home Road

Amherst NY 14228

146 Medinah Drive

Blue Bell PA 19422-3212

650 Gateway Blvd

South San Francisco CA 94080

981F Industrial Road

San Carlos CA 94070

San Carlos Business Park

981F Industrial Road

Immeuble "Le Guillaumet"

60, avenue du General de Gaulle

5 Moore Drive

Research Triangle Park NC 27709

460 Seaport Court

Suite 220

102 Tremont Way

Augusta GA 30907

99 Hayden Avenue

Lexington MA 02420-9192

Glendale CA 91203

36424

31716

Braintree MA 02184

San Carols CA 94070-4117

Redwood CA 94063

33217

Route 23 & Woodmont Ave., P.O. Box 1510

King Of Prussia PA 19406

2910 Seventh Street

Berkeley CA 94710

216 Bath Road

Slough SL1 4EN

Merit E. Cudkowicz, MD, MSc

Building 149 13th Street, Room 2274

P.O. Box 376

Ann Arbor MI 48106

7824 Jackson Street

Omaha NE 68114

Amores #1034 Col Del Valle

C.P. 03100 Mexico D.F.

One Kendall Square

Cambridge MA 02139-1562

1440 Davey Road

Woodridge IL 60517

33 ImClone Drive

Branchburg NJ 08876

33 ImClone Drive

Branchburg NJ 08876

Leinenweberstrasse 5

9041 Freiburg, GERMANY

800 South Frederik Avenue, Suite 300

Gaithersburg MD 20877

901 Sawyer Road

Marietta GA 30062

Grillparzerstrasse 10B

81675 Munich

200 Great Valley Parkway

Malvern PA 19355-1307

200 Great Valley Parkway

Malvern PA 19355-1307

7150 Alexander-Fleming

Charlestown MA 02129

37735

38777

30525

210 Welsh Pool Road

Exton PA 19341

244 Great Valley Parkway

Malvern PA 19355

9298 Gaither Road

Rockville MD 20877

Sharon Wood Technical Center

11370 Reed Hartman Highway

Leinenweberstrasse 5

Postfach 6529

275, avenue Labrosse

Pointe-Claire

Feinberg School of Medicine, Dept. of Gastroentero

676 N. St. Clair St., Suite 1400

61 Moulton Street

Cambridge MA 02138

8500 Hidden River Pkwy.

Tampa FL 33637

One Technology Place

Rockland MA 02370

777 Old Saw Mill River Road

Tarrytown NY 10591

3200 Walnut Street

Boulder CO 80301

3200 Walnut Street

Boulder CO 80301

One Amgen Center Drive

300 Elliott Avenue West

Seattle WA 98119

11 Deer Park Drive

Monmouth Junction NJ 08852-1923

34700 Campus Drive

Fremont CA 94555-3612

34700 Campus Drive

Fremont CA 94555-3612

P.O. Box 2500

Smithtown NY 11787

100 Fairway Drive, Suite 134

Vernon Hills IL 60061

Cincinnati OH 45241

Chicago IL 60611

Thousand Oaks CA 91320-1799

38054

33148

920 US Highway 202

P.O. Box 300

Raritan NJ 08869

Route 202, P.O. Box 300

Raritan NJ 08869

1125 Tenton-Harbourton Road

P. O. Box 200

Titusville NJ 08560

920 Route 202

PO Box 300

Raritan NJ 088690602

Route 202 South, P.O. Box 300

Raritan NJ 08869-0602

34026

Gewerbestrasse 16

235 East 42nd Street

150-3-46

New York NY 10017

7000 Portage Road

Unit 0633-298-113

Kalamazoo MI 490010199

3423 Hill Canyon Avenue

Thousand Oaks CA 91360

4545 Horizon Hill Blvd.

San Antonio TX 78229-2263

4545 Horizon Hill Blvd.

San Antonio TX 78229-2263

38349

59 Route 10

East Hanover NJ 07936

31761

340 Kingsland Street

Nutley NJ 07110

PO Box 16532

Columbus OH 43216-6532

40 Valley Stream Parkway

Malvern PA 19335

150 Broadway

Suite 1800

480 Arsenal Street

Watertown MA 02472

The Children's Hospital

300 Longwood Avenue, Bader 760

Two Connell Drive

Berkeley Heights NJ 07922

500 Arcola Road, P.O. Box 1200

Collegeville PA 19426

35340

New York NY 10038

Boston MA 02115

33836

5555 Valley Boulevard

Los Angeles CA 90032

33238

87 Cambridge Park Drive

Cambridge MA 02140

35472

100 College Road West

Princeton NJ 08540

39003

100 College Road West

Princeton NJ 08540

100 College Road West

Princeton NJ 08540

38544

100 College Road West

Princeton NJ 08540

39003

100 College Road West

Princeton NJ 08540

38576

100 College Road West

Princeton NJ 08540

100 College Road West

Princeton NJ 08540

100 College Road West

Princeton NJ 08540

100 Overlook Center

Suite 200

Princeton NJ 085407810

4520 East-West Highway

Third Floor

Bethesda MD 20814

825 Challenger Drive

Green Bay WI 54311

1100 Orthodox Street

Philadelphia PA 19124

1100 Orthodox Street

Philadelphia PA 19124

661 Palisade Ave., P.O. Box 931

Englewood Cliffs NJ 07632

5 Moore Drive

Research Triangle Park NC 27709

33087

5 Moore Drive

Research Triangle Park NC 27709

33087

5 Moore Drive

P.O. Box 13398

40 Valley Stream Parkway

Malvern PA 19355

230 Third Avenue

Waltham MA 02451

321 Arsenal Street

Watertown MA 02472

38544

Research Triangle Park NC 27709

36244

957 Budkingham Avenue

Slough

1824 S. Robertson Blvd.

Los Angeles CA 90035-4317

421 Wakara Way

Salt Lake City UT 84108

14785 Omicron Drive

San Antonio TX 78245

400 Rella Boulevard, Suite 201

Suffern NY 10901

1387 Marina Way South

Richmond CA 94804

35208

4002 Basel

Level 1, 82 Waterloo Road

North Ryde NSW, 2113

228 Hamilton Avenue

Palo Alto CA 94301

580 California St.

Suite 1600

San Francisco CA 94104

755 Jefferson Rd

P.O. Box 1710

Rochester NY 14603

32864

755 Jefferson Rd.

P.O. Box 1710

Rochester NY 14603

30958

56 Evergreen Drive

Portland ME 04103

Division of Pediatric Allergy & Immunology

Erwin Road

3525 John Hopkins Court

San Diego CA 92121

3525 John Hopkins Court

San Diego CA 92121

3525 John Hopkins Court

San Diego CA 92121

Hoarborside Financial Center

Plaza 10, 14th Floor

Jersey City NJ 07302

950 Tower Lane

Suite 790

Foster City CA 94404

Tecnology Ventures Corporation Technopolis

1155 University Blvd., SE

Albuquerque NM 87106

950 Tower Lane

Suite 790

Foster City CA 94404

Durham NC 27710

2525 Dupont Drive

P.O. Box 19534

Irvine CA 92623-9534

2525 Dupont Drive

P.O. Box 19534

Irvine CA 92623-9534

Batiment Genavenir IV

F-91058-Evry cedex

Harborside Financial Center

Plaza 10, 14th Floor

Jersey City NJ 07302

200 Westpark Corporate Center

4364 South Alston Avenue

Durham NC 277132280

College Of Veterinary Medicine

Department of Small Animal Medicine

Athens GA 30602

300 Fairfield Road

Wayne NJ 07470

University of Michigan Medical School

300 NIB, 1192 SE

Ann Arbor MI 481090408

781 Chestnut Ridge Road

P.O. Box 4310

Morgantown WV 26504

800 South Frederick Avenue

Gaithersburg MD 20877

One Mountain Rd.

P.O. Box 9322

12111 Parklawn Drive

Rockville MD 20852

One Mountain Road

P.O. Box 9322

938 Clopper Road

Gaithersburg MD 20878

10450 Science Center Drive

San Diego CA 92121

Medical University of South Carolina

96 Jonathan Lucas Street, Suite 428 CSB Charleston SC 29425

10390 Pacific Center Court

San Diego CA 92121

10390 Pacific Center Court

San Diego CA 92121

305 South Street

Boston MA 02130-3597

Pharmaceutical Division, Biological Products

400 Morgan Lane

34561

Framingham MA 01701-9322

Framingham MA 01701-9322

36251

36133 New Haven CT 06516

35774

340 Kingsland Street

Nutley NJ 07110

P.O. Box 191

Norwich NY 13815

37 Cleveland Lane

P.O. Box 5290

Princeton NJ 08540

37 Cleveland Lane

P.O. Box 5290

Princeton NJ 08540

37 Cleveland Lane

P.O. Box 5290

Princeton NJ 08540

5 Research Parkway

Wallingford CT 06492

38896

5 Research Parkway

Wallingford CT 06492

38896

650 Cliffside Drive

San Dimas CA 91773

35163

Via Pian Scairolo, 6912 Pazzallo

Lugano

3, Azrieli Center

Triangular Tower 45th Floor

6611 Tributary Street

Baltimore MD 21224-6515

6611 Tributary Street

Baltimore MD 21224

6611 Tributary Street

Suite 200

Baltimore MD 21224

6611 Tributary Street

Suite 200

Baltimore MD 21224

59 Route 10

East Hanover NJ 07936-1080

Apotex Research Inc.

Toronto, Canada M9L 1T9

1095 10th Avenue, SE

Minneapolis MN 55414

Piazza XX Settembre, 2

Piazza XX Settembre, 2

22079 Villa Guardia (CO)

38839 38658

Via Belvedere 1

Villa Guardia, Italy 22079

505 Penobscot Drive

Redwood City CA 94063

6111 Royalmount Avenue, Suite 102

Montreal

2401 Foothill Drive

Salt Lake City UT 84109-1405

2401 Foothill Drive

Salt Lake City UT 84109-1405

55 Challenger Road

Ridgefield Park NJ 07660

Quebec H4P 2T4

36196 Eatontown NJ 077242274

Meridian Center II

Four Industrial Way West

64 Sidney Street

Cambridge MA 02139-4170

1020 First Avenue

PO Box 61501

King of Prussia PA 19406-0901

2525 Dupont Drive

P. O. Box 19534

Irvine CA 92623-9534

99 Wood Avenue

Suite 311

Iselin NJ 08830

Fruebjergvej 3, 2100

Copenhagen

39331

7000 Portage Road

Kalamazoo MI 49001-0199

34845

160 Eglinton Ave. East

Suite 600

30 Forest Notch

Cohasset MA 02025

1095 10th Avenue S.E.

Minneapolis MN 55414

University Of Utah Medical Center

50 North Medical Drive, Room 4R240

2-31 Koraibashi, Higashi-ku

Osaka 541

1000 Madison Ave.

Norristown PA 19403

1000 Madison Ave.

Norristown PA 19403

1000 Madison Ave.

Norristown PA 19403

Toronto, Ontario M4P 3B

Salt Lake City UT 84132

34400

1620 Waukegan Road

McGaw Park IL 60085

3300 Hyland Avenue

Costa Mesa CA 92626

2800 Plymouth Rd., P.O. Box 1047

Ann Arbor MI 48106

2400 West Lloyd Expressway

Evansville IN 47721

Route 611, P.O. Box 187

Swiftwater PA 18370

10 DeAngelo Drive

Bedford MA 01730

Langes Feld 13

Hameln

153 Second Avenue

Waltham MA 02451

640 Sasco Hill Road

Fairfield CT 06824

11008 Lamplighter Lane

Potomac MD 20854

130 Fifth Ave., N.

Seattle WA 98109-4933

130 Fifth Ave., N.

Seattle WA 98109-4933

5 Moore Drive

Research Triangle Park NC 27709

1301 Piccard Drive

Rockville MD 20850

800 South Frederick Avenue

Gaithersburg MD 20877

610 Herndon Parkway

Suite 750

Herndon VA 20170

c/o Univ. of Calif., San Diego

9500 Gilman Dr.

La Jolla CA 920930624

7301 East 22nd Street

Suite 10E

Tucson AZ 85710

7301 East 22nd Street

Suite 10E

Tucson AZ 85710

35640

38210

31524

33 Flying Point Road

Southampton NY 11968

1900 Patterson Street

Suite 104

3505 Riverview Circle

Moorhead MN 56560

29949 S.R. 54 West

Wesley Chapel FL 33543

103 Carnegie Center, Suite 102

Princeton NJ 08540

4470 Redwood Highway

San Rafael CA 94903

Chestnut Run, Maple Run

Centre Rd.

2215 Mock Road

Huntsville AL 35801

9373 Towne Center Dr.

Suite 100

San Diego CA 921213088

9200 Indian Creek Parkway

Building 9, Suite 200

Overland Park KS 66210

1000 Madison Ave

Norristown PA 19403

920 US Highway 202

P. O. Box 300

460 Point San Bruno Boulevard

South San Francisco CA 94080

One Health Plaza

East Hanover NJ 07936-1080

920 US Highway 202, P. O. Box 300

Raritan NJ 08869

215Bouchard Blvd

Dorval

Quebec H9S 1A9

1550 Plymouth St.

PO Box 7210

Mountain View CA 94039-7210

59, Bd Gal Martial Valin - 75015

Paris

100 Technology Drive

Suite 440 B

901 Sawyer Rd.

Marietta GA 30062

Nashville TN 37203

Wilmington DE 19805

Raritan NJ 08869

34333

39219

36339

Pittsburgh PA 15219

33960

13950 Ballantyne Corporate Place

Charlotte NC 28277

207 South Elliott Road PMB#231

Chapel Hill NC 27514

200 First Street Southwest

Rochester MN 55905

200 First Street Southwest

Rochester MN 55905

352 Knotter Drive

Cheshire CT 06410

352 Knotter Drive

Cheshire CT 06410

39157

59 Route 10/Bldg 122/N142

One Health Plaza

East Hanover NJ 07936-1080

11080 CirclePoint Road

Suite 200

Westminster CO 80020

460 Seaport Court

Redwood City CA 94063

P.O. Box 9627

Kansas City MO 64134

P.O. Box 9627

Kansas City MO 64134

10 Mountainview Road

Upper Saddle River NJ 07458

Parke-Davis Pharmaceutical Research Division

2800 Plymouth Road

Ann Arbor MI 48105

2825 Santa Monica Blvd.

2nd Floor

Santa Monica CA 90404-2429

4620 Creekstone Drive

Research Triangle Park

Durham NC 27703

4901 Searle Parkway

Skokie IL 60077

4901 Searle Parkway

Skokie IL 60077

200 West Arbor Drive

San Diego CA 92103-8450

Lilly Corporate Center

Indianapolis IN 46285

500 Iolab Drive

Claremont CA 91711

P.O. Box 151

Somerville NJ 08876

0634-298-113

7000 Portage Rd.

33205

Kalamazoo MI 4900136418 0199

1840 Dehavilland Drive

Thousand Oaks CA 91320

33238

1840 Dehavilland Drive

Thousand Oaks CA 91320

32660

920 U.S. Highway

Route 202, P.O. Box 300

Raritan NJ 088690602

Route 202 South

P.O. Box 300

Raritan NJ 08869

920 US Highway 202

P.O. Box 300

Raritan NJ 088690602

Route 202, P.O. Box 300

Raritan NJ 08869

3780 Hawthorn Court

Waukegan IL 60087

Five Moore Dr.

PO Box 13398

5 Moore Drive

Research Triangle Park NC 27709

5 Moore Drive

Research Triangle Park NC 27709

301 Henrietta Street

Kalamazoo MI 49001

300 American Road

Morris Plains NJ 07950

7220 Frederick Banting, Suite 100

Saint-Laurent

Quebec H4S 2A1

Feigin Center

Suite 1120

Houston TX 770302399

1 DNA Way

South San Francisco CA 94080-4990

1980 South Easton Road

Suite 250

P.O. Box 516, 107/2 MS10

St. Louis MO 63166

Research Triangle Park NC 27709-3398 36630

34962

Doylestown PA 18901

607 Herndon Parkway

Herndon VA 21070

51 University St.

Seattle WA 98101-2936

Parc Technologique du Canal

31521 Ramonville Saint Agne Cedex

Parc Technologique du Canal

31521 Ramonville Saint Agne Cedex

257 Cornelison Avenue

Jersey City NJ 07302

70 Wood Avenue, South

Iselin NJ 08830

100 Front Street

West Conshohocken PA 19428

Kings Park House, Laurelhill Business Park

Polmaise Road, Stirling FK7 9JQ

6300 West Old Shakoppe Rd.

Suite 110

Bloomington MN 55438-2318

6300 West Old Shakoppe Rd.

Suite 110

Bloomington MN 55438-2318

5775 West Old Shakoppe Rd.

Suite 100

Bloomington MN 55437-3107

Two Annabel Lane, Suite 220

San Ramon CA 94583

Two Annabel Lane, Suite 220

Suite 10

2001 Aliceanna Street

Baltimore MD 21231-3043

7000 Portage Road

Mail Stop: 0636-298-113

Kalamazoo MI 4900136454 0199

58 South Service Road

Suite 110

Melville NY 11747

100 College Road West

Princeton NJ 08540

100 College Road West

Princeton NJ 08540

1020 First Ave.

PO Box 61501

4225 Roosevelt Way

Seattle WA 98105

15 Skyline Dr.

Hawthorne NY 10532

36307

32499

31888

San Ramon CA 94583

King of Prussia PA 19406-0901

15 Skyline Dr.

Hawthorne NY 10532

301B College Road East

Princeton NJ 08540

Fetcham Park House

Leatherhead, Surrey KT22 9HD

61 Lincoln's Inn Fields

London WC2A 3PX

Childrens Hospital Los Angeles

4650 Sunset Blve, MS 55

Los Angeles CA 90027

Weissfrauenstr.9

D-60287

Frankfurt

100 Pelican Way

San Rafael CA 94901

5555 Valley Boulevard

Los Angeles CA 90032

310 East 67th Street

New York NY 10021

9342 Jeronimo Road

Irvine CA 92718

1840 Dehavilland Drive

Thousand Oaks CA 91320

1840 Dehavilland Drive

Thousand Oaks CA 91320

1840 Dehavilland Drive

Thousand Oaks CA 91320

34500

One Amgen Center Dr.

Thousand Oaks CA 91320-1799

35887

One Amgen Center Dr.

Thousand Oaks CA 91320-1799

1840 Dehavilland Drive

Thousand Oaks CA 91320

160 East 34th Street

New York NY 10016

15049 San Pablo Avenue, P.O. Box 4099

Richmond CA 94804

15049 San Pablo Avenue

P.O. Box 4099

Richmond CA 948040099

Post House, Suite 213

1720 Post Road East

Westport CT 068805643

P.O. Box 200

Titusville NJ 08560

34179

34687

35061

33346

38450

8500 Hidden River Parkway

Tampa FL 33637

Division of American Cyanamid Company

401 N. Middletown Road

340 Kingsland Street

Nutley NJ 07110-1199

340 Kingsland Street

Nutley NJ 07110-1199

194 Bureaux de la Colline - Batiment D

92213 Saint-Cloud Cedex

The Mount Sinai School of Medicine

One Gustave L. Levy Place

New York NY 100296574

Dept. of Psychiatry

Box 1230, One Gustave L. Levy Place

New York NY 100296574

100 Longwater Circle

Norwell MA 02061

36670

3180 Porter Drive

Palo Alto CA 94304

36868

3180 Porter Drive

Palo Alto CA 94304

35768

2800 Plymouth Road

Ann Arbor MI 48106

35282

3260 Whipple Road

Union City CA 94587-1217

Av de Sevelin, 18-20

Lausanne, Switzerland

1140 Veterans Blvd.

Suite A

South San Francisco CA 94080

1140 Veterans Blvd.

Suite A

South San Francisco CA 94080

Parke-Davis Pharmaceutical Research Division

2800 Plymouth Road

Ann Arbor MI 48105

1845 Tonne Road

Elk Grove Village IL 60007

18-01 River Road

Fair Lawn NJ 07410

University of Massachusetts Medical Center

55 Lake Avenue

Pearl River NY 10965

33255

Worcester MA 01655

21 Business Park Drive

Branford CT 06405

3110 Cherry Palm Drive

Tampa FL 33619

9342 Jeronimo Road

Irvine CA 92718-1903

35128

3401 Hillview Avenue

Palo Alto CA 94304

32682

3030 Cornwallis Road

P.O. Box 12700

1401 Eye Street, N.W. Suite 900

Washington DC 20005

One Amgen Center Drive

Mail Stop 17-2-A

PO Box 8299

Philadelphia PA 19101-8299

1 Fitzroy Mews

London W1T6DE

10660 Scripps Ranch Blvd.

Suite 200

505 Irving Avenue

Syracuse NY 13210

9 West 57th Street

Suite 3825

One Research Way

Princeton NJ 08540

1510 Delp Drive

Kulpsville PA 19443

1090 Horsham Road

North Wales PA 19454

5214 Maryland Way, Suite 405

Brentwood TN 37027

4364 South Alston Avenue

Durham NC 27713

Subsidiary of Medicis Pharmaceutical Corporation

Scottsdale AZ 85258

Johns Hopkins University

Kennedy Krieger Institute, 707 North Broadway

Baltimore MD 21205

Five Concourse Parkway

Suite 1800

Atlanta GA 30328

Research Triangle Park NC 27709

Thousand Oaks CA 91320-1799

36663

San Diego CA 92131

New York NY 100192701

35419

38148

200 Great Valley Parkway

Malvern PA 19355-1307

400 Rella Boulevard, Suite 201

Suffern NY 10901

The New York Hospital - Cornell Medical Center 525 East 68th Street, Box 70

32791

New York NY 10021

500 Kendall Street

Cambridge MA 02142

2000 Galloping Hill Road

Kenilworth NJ 07033

2000 Galloping Hill Road

Kenilworth NJ 07033

2000 Galloping Hill Road

Kenilworth NJ 07033

2000 Galloping Hill Road

Kenilworth NJ 07033

2000 Galloping Hill Road

Kenilworth NJ 07033

12280 Wilkins Avenue

Rockville MD 20852

One Enterprise Way

Aliso Viejo CA 92656

59 Route 10

East Hanover NJ 07936-1080

311 Bonnie Circle

PO Box 1900

Corona CA 917181900

5 Research Parkway

P.O. Box 5100

Wallingford CT 06492-7660

352 Knotter Drive

Cheshire CT 06410

One Franklin Plaza

P.O. Box 7929

Textile House, 2 Koifman St.

Tel-Aviv 68012

9801 Washingtonian Blvd

Suite 220

Gaithersburg MD 20878

16020 Swingley Ridge Road

Suite 145

Chesterfield MO 63017

Immeuble Le Guillaumet

92046 Paris La Defense

Immeuble Le Guillaumet

70 avenue du General de Gaulle,

Philadelphia PA 19101

92056 Paris La Defense

33809

30517

Diagnostics Division

Abbott Park IL 60064

University Of Massachusetts Medical Center

55 Lake Avenue North

1 Prospect West

Wiltshire SN14 6FH

261 Aldwick Road

West Sussex PO21 3QU

96 Skyway Avenue

M9W 4Y4

12280 Wilkins Avenue

Rockville MD 20852

12276 Wilkins Avenue

Rockville MD 20852

65 Hayden Avnue

Lexington MA 02421

938 Clopper Road

Gaithersburg MD 20878

777 Old Saw Mill River Road

Tarrytown NY 10591

777 Old Saw Mill River Road

Tarrytown NY 10591

33 Hayden Avenue

Lexington MA 02421

University of Texas Medical Branch at Galveston

Route J-09, 700 The Strand

Galveston TX 77550

Meridian Center III

6 Industrial Way West

Eatontown NJ 07724

4954 Van Nuys Boulevard

Sherman Oaks CA 91403

9373 Towne Centre Dr., Suite 100

San Diego CA 92121

2730 Wilshire Blvd. #110

Santa Monica CA 90403

500 Arcola Road

Collegeville PA 19426

Nventa Biopharmaceuticals Corporation 6055 Lusk Boulevard

34801 Campus Drive

Fremont CA 94555

c/o Genzyme Corporation

1 Mountain Rd.

Worcester MA 01655

39205

San Diego CA 194262655

Framingham MA 01701-9322

33596

1801 Maple Avenue

Suite 4300

519 Route 173 West

Bloomsbury NJ 08804

Tolbodgade 33

DK-1253 Copenhagen K

200 Great Valley Parkway

Malvern PA 19355-1307

200 Great Valley Parkway

Malvern PA 19355-1307

One Kendall Square

Cambridge MA 02139

500 Kendall Street

Cambridge MA 02142

66 Ford Road

Denville NJ 07834

70 Calle Encanto

Tucson AZ 85716

70 Calle Encanto

Tucson AZ 85716

7310 Turfway Road

Suite 490

244 Great Valley Parkway

Malvern PA 19355

244 Great Valley Parkway

Malvern PA 19355

Evanston IL 60201

Florence KY 41042

P. O. Box 625

5800 Park of Commerce Blvd., NW

Boca Raton FL 33487

5800 Park of Commerce Blvd., N.W.

Boca Raton FL 33487

5800 Park of Commerce Blvd., NW

Boca Raton FL 33487

519 Route 173 West

Bloomsbury NJ 08804

5 Research Parkway

Signature 91 Bldg/3SIG-3012

140 West 57th Street

New York City NY 10019

322 East Main Street

Branford CT 06405

Rehhagstrsase

Wallingford CT 06492

200 Great Valley PArkway

Malvern PA 19355-1307

5885 Trinity Parkway

Suite 350

Centreville VA 20120

Koigle Alle 6

1000 Research Parkway

Meriden CT 06450

200 Great Valley Parkway

Malvern PA 19355-1307

1500 East Gude Drive

Rockville MD 20850

500 Kendall Street

Cambridge MA 02142

Building 75, 3rd. Ave.

Charlestown Navy Yard

340 Kingsland Street

Nutley NJ 07110-1199

3030 Callan Rd.

San Diego CA 92121

600 Alexander Park

Suite 304

210 Welsh Pool Road

Exton PA 19341

1301 Shoreway Road

Suite 320

Belmont CA 94002

790 W. Frontage Road

Suite 125

Northfield IL 60093

37 rue Saint Romain

69008 Lyon

3180 Porter Drive

Palo Alto CA 94304

Mile 5.0 Pass Creek Road

PO Box 24

6200 Seaforth Street

Baltimore MD 21224

P.O. Box 4000

Princeton NJ 08543

Charlestown MA 02129

Princeton NJ 08540

39066

Elk Mountain WY 82324

35851

2751 Centerville Rd., Suite 210

Wilmington DE 19808

2751 Centerville Rd., Suite 210

Wilmington DE 19808

840 Memorial Drive

Second Floor

Cambridge MA 02139

d/b/a GlaxoSmithKline

P. O. Box 7929

Philadelphia PA 19101

5200 research Place

San Diego CA 92122

1720 Post Road East

Suite 213

Westport CT 068805643

1720 Post Road East

Suite 213

Westport CT 068805643

Invalidenstr. 130

10115 Berlin

Invalidenstr, 130

10115 Berlin

Renal Division

1620 Waukegan Road

McGaw Park IL 60085 37610

7000 Portage Road

Unit 0633-298-113

Kalamazoo MI 490010199

7000 Portage Road

Unit 0633-298-113

Kalamazoo MI 490010199

P.O. Box 16529

Columbus OH 43216

7000 Portage Road

Unit 0633-298-113

Hammerstrasse 47

Hammerstrasse 47

Hammerstrasse 25

CH-4410 Liestal

225 East Deerpath, Suite 250

Lake Forest IL 60045

37306

38820

33143 Kalamazoo MI 490010199

700 Main Street

Cambridge MA 02139

38922

5 Research Parkway, P.O. Box 5100

Wallingford CT 06492

32507

P.O. Box 4000

Princeton NJ 08543-4000

P.O. Box 4000

Princeton NJ 08543

150 Field Drive

Suite 195

Lake Forest IL 60045

1210-885 West Georgia

Vancouver, British Columbia

San Diego

5000 Shoreline Court

South San Francisco CA 94080

300 Fairfield Road

Wayne NJ 07470

300 Fairfield Road

Wayne NJ 07470

59 Route 10

East Hanover NJ 07936-1080

37021

One Health Plaza

East Hanover NJ 07936-1080

39009

One Health Plaza

East Hanover NJ 07936-1080

39009

One Health Plaza

East Hanover NJ 07936-1080

39009

One Health Plaza

East Hanover NJ 07936-1080

39009

One Health Plaza

East Hanover NJ 07936-1080

39009

One Health Plaza

East Hanover NJ 07936-1080

37288

244 Great Valley Parkway

Malvern PA 19355

4380 N. Campbell Ave.

Tucson AZ 85718

2321 Camino La Zorrela

Tucson AZ 85718

38350

2321 Camino La Zorrela

Tucson AZ 85718

2321 Camino La Zorrela

Tucson AZ 85718

One Kendall Square

Cambridge MA 02139-1562

15222 Avenue of Science

Suite C

8368 US 70 West

Clayton NC 27520

Plasma Fractionation Institute

Ramat Gan 52621

Wankdorfstrasse 10

CH-3000 Bern 22

Baxter Bioscience

Westlake Village CA 91362

750 Lexington Avenue

New York NY 10022

155 East 56th Street

New York NY 10022

750 Lexington Avenue, 19th Floor

New York NY 10022

Pharmaceutical Division, Biological Products

400 Morgan Lane

New Haven CT 06516 34330

1020 First Avenue

P.O. Box 61501

King of Prussia PA 19406-0901

2 Tesseneer Drive

Highland Heights KY 41076

Research Center

27 Village Lane

76 Rogers Street

Cambridge MA 02142

244 Great Valley Parkway

Malvern PA 19355

11095 Torreyanna Road

San Diego CA 92196

9701 Richmond Avenue

Houston TX 77042

200 Great Valley Parkway

34477

San Diego CA 92128

Wallingford CT 06492

Malvern PA 193551307

200 Great Valley Parkway

Malvern PA 19355-1307

200 Great Valley Parkway

Malvern PA 19355-1307

200 Great Valley Parkway

Malvern PA 19355-1307

200 Great Valley Parkway

Malvern PA 19355-1307

200 Great Valley Parkway

Malvern PA 19355-1307

38856

36031

2250 Holcombe Blvd

Houston TX 77030

8995 Westside Parkway

Suite 150

Alpharetta GA 30004

3, allee des sequoias*

69760 LIMONEST - France

897 West Sixteenth Street

Newport Beach CA 92663

340 Kingsland Street

Nutley NJ 07110

340 Kingsland Street

Nutley NJ 07110-1199

340 Kingsland Street

Nutley NJ 07110

340 Kingsland Street

Nutley NJ 07119

340 Kingsland Street

Nutley NJ 07110

340 Kingsland Street

Nutley NJ 07110-1199

340 Kingsland Street

Nutley NJ 07110-1199

2000 Galloping Hill Road

Kenilworth NJ 07033

2000 Galloping Hill Road

Kenilworth NJ 07033

2000 Galloping Hill Road

Kenilworth NJ 07033

2000 Galloping Hill Road

Kenilworth NJ 07033

34991

32468

32468

2000 Galloping Hill Road

Kenilworth NJ 07033

2000 Galloping Hill Road

Kenilworth NJ 07033

2000 Galloping Hill Road

Kenilworth NJ 07033

2000 Galloping Hill Road

Kenilworth NJ 07033

2000 Galloping Hill Road

Kenilworth NJ 07033

2000 Galloping Hill Road

Kenilworth NJ 07033

5 Moore Drive

Research Triangle Park NC 27709

3030 Cornwallis Road

Research Triangle Pk NC 27709

14 Cambridge Center

Cambridge MA 02142

14 Cambridge Center

Cambridge MA 02142

14 Cambridge Center

Cambridge MA 02142

15049 San Pablo Avenue, P.O. Box 4099

Richmond CA 94804

100 Longwater Circle

Norwell MA 02061

14 Cambridge Center

Cambridge MA 02142

14 Cambridge Center

Cambridge MA 02142

14 Cambridge Center

Cambridge MA 02142

100 Longwater Circle

Norwell MA 02061

4560 Horton Street

Emeryville CA 94608

3280 Bayshore Blvd

Brisbane CA 94005

1710 Gilbreth Road,

Suite 301

1 DNA Way

South San Francisco CA 94080-4990

35202

34173

33227 Burlingame CA 94010-1317

36566

Center for Cancer Drud Discovery and Development

9500 Euclid Avenue

51 University Street

Seattle WA 98101

51 University Street

Seattle WA 98101

One Amgen Center Drive

Thousand Oaks CA 91320-1799

One Amgen Center Drive

Thousand Oaks CA 91320-1799

777 Old Saw Mill River Road

Tarrytown NY 10591

777 Old Saw Mill River Road

Tarrytown NY 10591

340 Kingsland Street

Nutley NJ 07110

340 Kingsland Street

Nutley NJ 07110

340 Kingsland Street

Nutley NJ 07110

340 Kingsland Street

Nutley NJ 07110

51 University Street

Seattle WA 98101

59 Route 10

East Hanover NJ 07936

1120 Win Drive

Bethlehem PA 18017

Clevland OH 44195

39 Jerusalem Street

101 Carnegie Center

Princeton NJ 08540

101 Carnegie Center

Princeton NJ 08540

Div. of Draxis Specialty Pharmaceuticals, Inc.

Kirkland, Quebec H9H 4J4

160 Second street

Cambridge MA 02142

UH B1 H410/0028

1500 E. Medical Center Drive

312 Lacebark Street

Schererville IN 46375

312 Lacebark Street

Schererville IN 46375

Ann Arbor MI 481090028

32953

University of Michigan Medical Center/1500 E. Med.

B1G412 /0028 University Hospital

Ann Arbor MI 481090028

300 American Road

Morris Plains NJ 07950

300 American Road

Morris Plains NJ 07950

300 American Road

Morris Plains NJ 07950

300 American Rd.

Morris Plains NJ 07950

American Cyanamide Company

401 N. Middletown Road

300 American Road

Morris Plains NJ 07950

300 American Road

Morris Plains NJ 07950

300 American Road

Morris Plains NJ 07950

300 American Road

Morris Plains NJ 07950

14282 Franklin Ave.

Tustin CA 92780-7017

5775 West Old Shakoppe Rd.

Suite 100

Bloomington MN 55437-3107

5775 West Old Shakoppe Rd.

Suite 100

Bloomington MN 55437-3107

Goerzallee 253

D-14167 Berlin, Federal Republic of Germany

5555 Valley Boulevard

Los Angeles CA 90032

Boston University

Cancer Research Center

6 Cedar Brook Drive

Cranbury NJ 08512

Room 307, Koryo Academytel, 437-3

Ahyun-Dong, Mapo-Gu, Seoul 121-010

28101 Ballard Road

Lake Forest IL 60045

640 Memorial Drive, 3rd Floor West

Cambridge MA 02139

Pearl River NY 10965

37896

Boston MA 02118

640 Memorial Drive, 3rd Floor West

Cambridge MA 02139

311 Bonnie Circle

P.O. Box 1900

Corona CA 917181900

SUNY Farmingdale

Conklin Hall

Farmingdale NY 11735

800 S. Frederick Avenue

Gaithersburg MD 20877

800 S. Frederick Ave.

Gaithersburg MD 20877

P.O. Box 16532

Columbus OH 43216-6532

200 International Circle

Hunt Valley MD 21030

5 Moore Drive

P.O. Box 13398

27 Maple Street

Milford MA 01757

39324

371 Bel Marin Keys Boulevard, Suite 210

Novato CA 94949-5608

37741

1101 Kermit Drive, Suite 608

Nashville TN 37217

6111 Royalmount, Suite 100

Montreal, Quebec H4P 2T4

6111 Royalmount, Suite 100

Montreal, Quebec H4P 2T4

6111 Royalmount, #100

Montreal, Quebec H4P 2T4

University Of Pittsburgh School of Medicine

Pittsburgh PA 15261

The City College, City University Of NY Medical Sc

Convent Avenue at 138 Street

New York NY 10031

Channing Laboratory

Dept. of Medicine

Boston MA 02115

Rush-Presbyterian-St. Luke's Medical Ctr., Dept. o

1653 West Congress Parkway

Chicago IL 606123833

86 Morris Avenue

Summit NJ 07901

86 Morris Avenue

Summit NJ 07901

86 Morris Avenue

Summit NJ 07901

Research Triangle Park NC 27709

36031

38713

38897

200 West Jackson Blvd.

Chicago IL 60606

Frankfurt am Main

P.O. Box 1140

41 Moores Road

Frazer PA 19355

51 University Street

Seattle WA 98101

33584

51 University Street

Seattle WA 98101

32386

5 Moore Drive

PO Box 13398

Research Triangle Park NC 27709

8229 Boone Blvd.

Suite 802

Vienna VA 22182

S.U.N.Y. at Stony Brook

H.S.C. T18-020

Stony Brook NY 11794-8181

2355 Waukegan Road

Deerfield IL 60015

500 Iolab Drive

Claremont CA 94608

Marburg

35860

34075

36509

800 South Frederick Avenue, Suite 300 Gaithersburg MD 20877 800 South Frederick Avenue

Gaithersburg MD 20877

800 South Frederick Avenue

Gaithersburg MD 20877

800 South Frederick Avenue

Gaithersburg MD 20877

800 S. Frederick Avenue, Suite 300

Gaithersburg MD 20877

800 South Frederick Avenue

Gaithersburg MD 20877

800 South Frederick Avenue

Gaithersburg MD 20877

33954

800 South Frederick Avenue

Gaithersburg MD 20877

31512

901 Sawyer Road

Marietta GA 30062

8180 Greensboro Drive, Suite 1000

McLean VA 22102

3870 Del Amo Blvd

Unit 507

P. O. Box 2072.

Toowong Business Center

34159 Torrance CA 905037701

600 College Road East

Princeton NJ 08540

745-D Camden Ave.

Campbell CA 95008-4146

21823 30th Drive Southeast

Bothell WA 98021

21823 30th Drive Southeast

Bothell WA 98021

34801 Campus Drive

Fremont CA 94555

One Franklin Plaza

P.O. Box 7929

Philadelphia PA 19101

Metrowest Place

15 Pleasant Street Connector

Framingham MA 01701-9322

3 Parkway North Center

Deerfield IL 60015

3 Parkway North Center

Deerfield IL 60015

35653

3 Parkway North Center

Deerfield IL 60015

35653

420 Lexington Avenue

New York NY 10170

420 Lexington Avenue

New York NY 10170

3929 Point Eden Way

Hayward CA 94545

3929 Point Eden Way

Hayward CA 94545

11 Deer Park Drive

Monmouth Junction NJ 08852-1923

Baylor College of Medicine, Dept. of Molecular Phy

One Baylor Plaza

Houston TX 77030

Pol. Ind. Els Vinyets els Fogars n 2,

Quinti de Mediona

Barcelona

900 North Shore Drive

Lake Bluff IL 60044

900 North Shore Drive

Lake Bluff IL 60044

36238

33603

M.D. Anderson Cancer Center

Unit 038

Houston TX 77030

20651 Prince Creek Dr.

Katy TX 77450

One Research Way

Princeton NJ 08540

3 Forbes Road

Lexington MA 02421

2011 - 94th Street

Edmonston, AB

2011 - 94th Street

T6N 1H1

201 Elliot Avenue West201

Suite 400

181 Cherry Valley Road

Princeton NJ 08540

181 Cherry Valley Road

Princeton NJ 08540

6201 South Freeway

Fort Worth TX 76134

Route 202, P.O. Box 300

Raritan NJ 08869

99 Hayden Ave., Suite 200

Lexington MA 02421-7966

12832 Chadron Avenue

Hawthorne CA 90250

1801 Maple Avenue

Suite 4300

Evanston IL 60201

Subsidiary of China Medical System Holdings Limite

Room 1404, 14th Floor

North Point

2600 Kelly Road

Warrington PA 18976

2600 Kelly Road

Warrington PA 18976

2600 Kelly Road

Warrington PA 18976

2600 Kelly Road

Warrington PA 18976

2600 Kelly Road

Warrington PA 18976

Seattle WA 98119

34235

4901 Searle Parkway

Skokie IL 60077

781 Chestnut Ridge Road

P.O. Box 4310

Route 120 & Wilson Road

Round Lake IL 60073-0490

26 Landsdowne Street

Cambridge MA 02139-4234

10 Rodborough Rd.

NSW 2086

P. O. Box 28

Richlands 4077

397 Eagleview Blvd.

Exton PA 19341

3 Francis St.

Belmont MA 02478

860 Atlantic Avenue

Alameda CA 94501

10865 Altman Row

Suite 200

176 Memorial Drive

Jesup GA 31545

200 East First St.

Suite 300

Winston-Salem NC 27101-4165

41 Moores Road

P. O. Box 4011

Frazer PA 19355

2000 Sierra Point Parkway

Suite 400

Brisbane CA 94005

38594

8720 Stony Point Parkway

Suite 200

Richmond VA 23235

38698

259 Radnor Chester Road

Radnor PA 19087

One MedImmune Way

Gaithersburg MD 20878

1787 Sentry Parkway West

Building 18, Suite 440

4143 Dornach

POSTFASH 137

Morgantown WV 26504-4310

35951

San Diego CA 921211113

Blue Bell PA 19422

4143 Dornach

POSTFASH 137

340 Kingsland Street

Nutley NJ 07110

32630

340 Kingsland Street

Nutley NJ 07110

32630

2400 West Lloyd Expressway

Evansville IN 47721

34222

Hoag Cancer Center Cell Biology Laboratory

Building 41

2110 Rutherford Road

Carlsbad CA 92008

5 Research Parkway

P. O. Box 5100

533 Old Corvallis Road

Hamilton MT 59840

8 Hanechoshet St.

Tel-Aviv

Oregon Health Sciences University

3181 S.W. Sam Jackson Park Road

Portland OR 97201

900 Ridgebury Road

P. O. Box 368

Ridgefield CT 0687738575 0368

5 Moore Drive

PO Box 13398

Research Triangle Park NC 27709

5 Moore Drive

Research Triangle Park NC 27709

146 Medinah Drive

Blue Bell PA 19422-3212

146 Medinah Drive

Blue Bell PA 19422-3212

P.O. Box 7929

Philadelphia PA 19101

1800 Concord Pike

PO Box 15437

890 East St.

Tewksbury MA 01876-1496

65 Challenger Road

Ridgefield Park NJ 07660

90 Gold Street, 6N

New York NY 10038

P.O. Box 8299

Philadelphia PA 19101-8299

Division of American Cyanamid Company

401 N. Middletown Road

Pearl River NY 10965 32240

200 Westpark Corporate Center

4364 South Alston Avenue

Durham NC 277132280

Newport Beach CA 92658

Wallingford CT 06492

33926

Wilmington DE 19850-5437

32507

437 Creamery Way

Exton PA 19431

9360 Towne Centre Drive

San Diego CA 92121

9360 Towne Center Drive

San Diego CA 92121

P.O. Box 331329

Fort Worth TX 76163

4901 Searle Parkway

Skokie IL 60077

P.O. Box 331329

Fort Worth TX 76163

2988 Cove Trace

Charlottesville VA 22911

55 Knollwood Road

Farmington CT 06032

2530 Meridian Parkway

Suite 3023

8010 Arco Corporate Drive

Raleigh NC 27617

Meridian Center III

6 Industrial Way West

9 Parker

Irvine CA 92618-1605

19, rue Frederick Lmaitre

75020 Paris

149 Commonwealth Drive

Menlo Park CA 94025

Gewerbestrasse 16

CH - 4123 Allschwi

32469

Durham NC 27713

Eatontown NJ 07724

37833

Weismullerstrasse 50 Division of American Cyanamid Company

401 N. Middletown Road

Autoimmunity Research, Inc.

Thousand Oaks CA 91360

15 East 26th Street

New York NY 10010

4545 Horizon Hill Blvd.

San Antonio TX 78229-2263

990 Station Road

Bellport NY 11713

35314

Pearl River NY 10965

990 Station Road

Bellport NY 11713

3100 Airway Avenue, Suite 106

Costa Mesa CA 92626

One Technology Place

Rockland MA 02370

35382

One Technoloogy Place

Rockland MA 02370

36812

One Technology Place

Rockland MA 02370

36812

Division of American Cyanamid Company

401 N. Middletown Road

300 American Rd.

Morris Plains NJ 07950

300 American Road

Morris Plains NJ 07950

145 Brandywine Parkway

West Chester PA 19380

2000 Galloping Hill Road

Kenilworth NJ 07033

2000 Galloping Hill Road

Kenilworth NJ 07033

Ackerstein Towers, Bldg B, 10th Floor

ISRAEL

3030 Callan Road

San Diego CA 92121

11011 Torreyana Road

San Diego CA 92121

244 Great Valley Parkway

Malvern PA 19355

2825 Santa Monica Blvd., Suite 200

Santa Monica CA 90404

2375 Garcia Avenue

Mountain View CA 94043

2375 Garcia Avenue

Mountain View CA 94043

34801 Campus Dr.

Fremont CA 94555

15 Walnut Street

Suite 300

Pearl River NY 10965 32134

36153

Wellesley Hills MA 02481

235 East 42nd Street

New York NY 10017

5 Moore Drive

PO Box 13398

7855 Gross Point Road, Unit L

Skokie IL 60077

31351

2 Esterbrook Lane

Cherry Hill NJ 08003

33438

999 East Arques Avenue

Sunnyvale CA 94085-4521

4330 La Jolla Village Drive

Suite #250

12280 Wilkins Avenue

Rockville MD 20852

12280 Wilkins Avenue

Rockville MD 20852

One Health Plaza

East Hanover NJ 07936-1080

725 Chesterbrook Blvd.

Wayne PA 19087-5677

Mack-Cali Centre II

Second Floor

Paramus NJ 07652

14272 Franklin Ave.

Suite 100

Tustin CA 92780

West Africa House

Hanger Lane Ealing

London W5 3QR

345 Pioneer Drive, 1803W

Glendale CA 91203

5 Artillerivej

DK-2300 Copenhagen S

340 Kingsland Street

Nutley NJ 07110

340 Kingsland Street

Nutley NJ 07110

128 Spring Street

Lexington MA 02173

Abbott Laboratories

625 Cleveland Ave.

5600 Parkwood Way

Suite 425

3, avenue George V

One Amgen Center Drive

Thousand Oaks CA 91320-1799

Research Triangle Park NC 27709

San Diego CA 92122

Columbus OH 432151724

38239

130 Waverly St.

Cambridge MA 02139-4242

2525 - 28th Street

Boulder CO 80301

3, avenue George V Abbott Park IL 600646157

Pharmaceuticals Products Division

D-491, AP30-1E

555 Madison Avenue

New York NY 10022

Global Pharmaceuticals Research & Development

Abbott Park IL 60064

93 Worcester Street

Suite 101

Wellesley MA 02481

93 Worcester Street

Suite 101

Wellesley MA 02481

93 Pederstrupvej

DK-2750 Ballerup

Road 198, No. 100 km. 14.7

Juncos Industrial Park

Juncos UN 007773873

University of Texas Southwestern Medical Center at

5323 Harry Hines Blvd

Dallas TX 753909151

105 Digital Drive

Novato CA 94949-5608

11 Deer Park Drive

Monmouth Junction NJ 08852

8455 Beverly Blvd.

Suite 308

3560 Pennsylvania Avenue, Suite 7

Dubuque IA 52002

Pharmaceutical Products Division

200 Abbott Park Road

3401 Hillview Avenue

Palo Alto CA 94303

33660

E.I. Du Pont De Nemours & Co.

Wilmington DE 19880

31016

4134 Business Park Drive

Amarillo TX 79110

4134 Business Park Drive

Amarillo TX 79110

38503

Los Angeles CA 90048

Abbott Park IL 60064

4134 Business Park Drive

Amarillo TX 79110

33 Ralph Avenue

P.O. Box 30

200 Great Valley Parkway

Malvern PA 19355

One Franklin Plaza

Phildelphia PA 19101

Copiaque NY 117260030

38653

6560 Fannin, Scurlock Tower, Suite 720 Houston TX 77303 400 Rella Boulevard, Suite 201

Suffern NY 10901

MetroHealth Medical Center

3395 Scranton Road

University of Arizona

Tucson AZ 85723

One Health Plaza

East Hanover NJ 07936-1080

One Health Plaza

East Hanover NJ 07936-1080

5045 Orbitor Drive

Mississauga, Ontario L4W 4Y4

New Brunswick Technology Center

New Brunswick NJ 100 Jersey Avenue, Building B, Suite 310 08901

6200 Courtney Campbell Causeway

Suite 880

Tampa FL 33607

6200 Courtney Campbell Causeway

Suite 880

Tampa FL 33607

37582

6200 Courtney Campbell Causeway

Suite 880

Tampa FL 33607

37582

Kungsgatan 37, 7th Floor

SE-111 56

Drottninggatan 98

SE-111 60 Stockholm

22705 Savi Ranch Parkway

Yorba Linda CA 92887-4645

6 Route 173

Clinton NJ 08809

Cleveland OH 44109

37274

36517

54 Old Highway 22

Clinton NJ 08809

54 Old Highway 22

Clinton NJ 08809

Thomas Jefferson University and Wills Neurosensory

834 Walnut Street, Suite 650

Philadelphia PA 19107-5102

La Jolla Laboratories

10646 Science Center Drive

San Diego CA 92121

675 Almanor Avenue

Sunnyvale CA 94085-1

640 S. Fourth Street

Louisville KY 40202

West Africa House

London W5 3QR

800 Research Parkway

Suite 200

5 Great Valley Parkway

Malvern PA 19355

5 Great Valley Parkway

Malvern PA 19355

5 Great Valley Parkway

Malvern PA 19355

Two Connell Drive

Berkeley Heights NJ 07922

59 Route 10

East Hanover NJ 07936-1080

36124

59 Route 10

East Hanover NJ 07936-1080

36124

59 Route 10

East Hanover NJ 07936-1080

36124

2525 Dupont Drive

P.O. Box 19534

P. O. Box 2072

Toowong Business Center

6001 Savoy, Suite 110

Houston TX 77036

3715 Haven Avenue

Menlo Park CA 94025

Oklahoma City OK 73104

Irvine CA 92713

35207

4364 South Alston Avenue

Durham NC 27713

PO Box 420

1327 Lysaker

600 College Road East

Princeton NJ 08540

87 Cambridge Park Drive

Cambridge MA 02140

863 Mitten Road, Suite 101

Burlingame CA 94010

6040 N. Cutter Circle, Suite 317

Portland OR 97217-3935

40 Landsdowne Street

Cambridge MA 02139

Rue des Terreaux 17

CH-1000

13709 Progress Blvd. #17

Alachua FL 32615

70 Wood Avenue, South

Iselin NJ 08830

70 Wood Avenue, South

Iselin NJ 08830

35759

37754

One Tower Center Boulevard, 12th floor East Brunswick NJ 08816 One Tower Center Boulevard, 12 th floor East Brunswick NJ 08816 70 Wood Avenue South

Iselin NJ 08830

3180 Porter Drive

Palo Alto CA 94304

38674

3180 Porter Drive

Palo Alto CA 94304

37454

P.O. Box 80027

Wilmington DE 19880

3650 Westbrook Mall

Vancouver, B.C.

4222 Emperor Blvd.

Suite 470

4222 Emperor Blvd., Suite 470

Durham NC 27703

Durham NC 27703

9410 Key West Avenue

Rockville MD 20850

5 Research Parkway

P.O. Box 5100

4400 Biscayne Boulevard

Miami FL 33137

22026 20th Avenue SE

Bothell WA 98021

150 Fairway Drive

Vernon Hills IL 60061

150 Fairway Drive

Vernon Hills IL 60061

150 Fairway Drive

Suite 150

22 Inverness Parkway

Birmingham AL 35242

One Health Plaza

East Hanover NJ 07936-1080

14851 N. Scottsdale Rd.

Scottsdale AZ 85254

417 Harvester Court

Wheeling IL 60090

300 Interpace Parkway

Parsippany NJ 07054

35 West Watkins Mill Rd.

Gaithersburg MD 20878

2420 Castillo Street, Suite 100

Santa Barbara CA 93105

One Health Plaza

East Hanover NJ 07936-1080

20 Kingsbridge Road

Piscataway NJ 08854

20 Kingsbridge Road

Piscataway NJ 08854

49 Convent Dr. MSC4405

Bldg. 49, Room B1EE16

340 Kingsland St.

Nutley NJ 07110-1199

Wallingford CT 06492-7660

35646

Vernon Hills IL 60061

32953

34366 Bethesda MD 208924405

340 Kingsland St.

Nutley NJ 07110-1199

4560 Horton Street

Emeryville CA 94608

Suite 430,

98 San Jacinto Boulevard

115 John Robert Thomas Dr.

Exton PA 19341

115 John Robert Thomas Dr.

Exton PA 19341

One Amgen Center Dr.

Thousand Oaks CA 91320-1789

2190 Parkway Lake Drive

Birmingham AL 35244

Lilly Corporate Center

Indianapolis IN 46285

38021

3 Parkway North Center

Deerfield IL 60015

32674

3 Parkway North Center

Deerfield IL 60015

30971

1020 First Avenue

PO Box 61501

755 Jefferson Rd., P.O. Box 1710

Rochester NY 14603

E.I. Du Pont De Nemours & Co.

Wilmington DE 19898

Goerzallee 253

Fedderal of Republic of Germany

950 Page Mill Rd.

PO Box 10950

Palo Alto CA 943030802

4140 Dublin Blvd.

Suite 200

Dublin CA 94568

4140 Dublin Blvd.

Suite 200

Dublin CA 94568

4140 Dublin Blvd.

Suite 200

Dublin CA 94568

4140 Dublin Blvd.

Suite 200

Dublin CA 94568

Avenida Carlos III el Noble

Pamplona (Navarra)

Avenida Carlos III el Noble, 36, 1 Dcha. 31003

Austin TX 78701

37705

King of Prussia PA 19406-0901

31916

35334

33522

38 Melville Street

Scotland

3040 Science Park Road

San Diego CA 92191

2450 Bayshore Parkway

Mountain View CA 94043

Cincinnati Children's Hospital Medical Center

3333 Burnet Ave.

1300 Gould Dr.

Gainesville GA 30504

371 Bel Marin Keys Blvd.

Suite 210

1300 Gould Dr.

Gainesville GA 30504

Unit 3, Hill Farm Industrial Estate

Leavesden, Watford

Port Jefferson Business Center

200 Wilson Street, Building D-6

Port Jefferson NY 11776

5775 West Old Shakopee Rd.

Suite 100

Bloomington MN 55437-3107

34415

5775 West Old Shakopee Rd.

Suite 100

Bloomington MN 55437-3107

35837

1950 Lake Park Drive

Smyrna GA 30080

3030 Cornwallis Road

P.O. Box 12700

11000 Cedar Avenue

Cleveland OH 44106

10 Fleet Place

London EC4M 7SB

10 Fleet Place

London EC4M 7SB

University Park at M.I.T.

The Richards Building 64

Cambridge MA 02139-4170

University Park at M.I.T.

The Richards Building 64

Cambridge MA 02139-4170

6611 Tributary Street

Baltimore MD 21224

Cincinnati OH 452293039

Novato CA 94949

Research Triangle Park NC 27709

37677

35331

6611 Tributary Street

Baltimore MD 21224

154 Technology Parkway

Norcross GA 30092

4606 Willow

Bellaire TX 77401

154 Technology Parkway

Norcross GA 30092

154 Technology Parkway

Norcross GA 30092

One Penn Center

1617 JFK Boulevard

Philadelphia PA 19103

One Penn Center

1617 JFK Boulevard

Philadelphia PA 19103

One Penn Center

1617 JFK Boulevard

Philadelphia PA 19103

One Penn Center

1617 JFK Boulevard

Philadelphia PA 19103

One Tower Center Boulevard, 14th floor East Brunswick NJ 08816

115 John Robert Thomas Dr.

Exton PA 19341

115 John Robert Thomas Dr.

Exton PA 19341

115 John Robert Thomas Dr.

Exton PA 19341

3202 Cleveland Avenue N.W.

Washington DC 20008

3203 Cleveland Ave., NW

Washington DC 20008-3450

3203 Cleveland Ave., NW

Washington DC 20008-3450

3203 Cleveland Ave., NW

Washington DC 20008-3450

P.O. Box 14

Bryn Mawr PA 19010

211 Central Park West

New York NY 10024

One Kendall Square

Cambridge MA 02139-1562

One Kendall Square

Cambridge MA 02139-1562

One Kendall Square

Cambridge MA 02129-1562

One Kendall Square

Cambridge MA 02139-1562

Post Office Plaza

50 Division Street, Suite 503

Somerville NJ 08876

22 Inverness Parkway

Suite 310

Birmingham AL 35242 37834

22 Inverness Parkway

Birmingham AL 35242

Lederle Laboratories

401 North Middletown Road

Pearl River NY 10965 35060

Lederle Laboratories

401 North Middletown Road

Pearl River NY 10965

900 Ridgebury Road

PO Box 368

Ridgefield CT 06877

900 Ridgebury Road

PO Box 368

Ridgefield CT 06877

2000 Galloping Hill Road

Kenilwortoh NJ 07033

5323 Harry Hines Blvd

Dallas TX 75235

31289

5323 Harry Hines Blvd

Dallas TX 75235

31289

5323 Harry Hines Boulevard

Dallas TX 75235

31289

1733 Gilsinn Lane

Fenton MO 63026

2958101

1564 33rd Street, NW

Washington DC 20007

P. O. Box 93921

Carmel CA 93921

P. O. Box 93921

Carmel CA 93921

P. O. Box 93921

Carmel CA 93921

2 Innovation Drive

Alachua FL 32615

2 Innovation Drive

Alachua FL 32615

2 Innovation Drive

Alachua FL 32615

2 Innovation Drive

Alachua FL 32615

11080 CirclePoint Road

Westminster CO 80020

1 Kendall Square, Bldg. 700

Cambridge MA 02139

P.O. Box 16529

Columbus OH 43216-6529

90 Park Avenue

New York NY 10016

800 South Frederick Avenue

Gaithersburg MD 20877

311 Bonnie Circle

Corona CA 91720

Pharmaceuticals Division

8500 Hidden River Parkway

Research & Development Division

2-5-1 Atago, Minato-ku, Tokyo

5555 Valley Boulevard

Los Angeles CA 90032

2159 Avenida de la Playa

Suite B

One Baxter Way

West Lake Village CA 91362

750 Lexington Avenue, 19th Floor

New York NY 10022

750 Lexington Avenue, 19th Floor

New York NY 10022

1950 Lake Park Drive

Smyrna GA 30080

200 Abbott Park Road

Abbott Park IL

2450 Bayshore Parkway

Mountain View CA 94043

2751 Napa Valley Corporate Drive

Napa CA 94558

200 Highland Avenue

Suite 30

128 Spring Street

Lexington MA 02421

Tampa FL 33637

La Jolla CA 92037

39171

2958101 Needham MA 02494

84 park Avenue

P.O. Box 968

Flemington NJ 08822

1100 Orthodox Street

Philadelphia PA 19124

11455 El Camino Real

San Diego CA 92130

11801 Research Drive

Suite D

University of Pittsburgh

Pittsburgh PA 15213

Lilly Corporate Center

Drop Code 1853

225 Belleville Ave.

Bloomfield NJ 07003

1275 Kinnear Road

Columbus OH 43212

26 Landsdowne Street

Cambridge MA 02139-4234

9 Great Valley Parkway

Malvern PA 19355

12085 Research Drive

Suite 110

Alachua FL 32615

Oncology Business Unit

One Health Plaza

East Hanover NJ 07986

Oncology Business Unit

One Health Plaza

East Hanover NJ 07936

2910 Seventh Street

Berkeley CA 94710

25 Riverside Drive

P.O. Box 102

Kongevejen 153

2830 Virum

3575 av. du Parc

Montreal, Quebec H2X 3P9

Alachua FL 32615

Toronto ON

Indianapolis IN 46285

37449

Pine Brook NJ 07058

Rue des Professeurs Jenner et Brachet, 12 B-6041-Gosselies 10 Four seasons Place

38576

M9B 6H7

6850 Goreway Dr.

Mississauga

One Kendall Square

Cambridge MA 02139

1010 Atlantic Avenue

Alameda CA 94501

2020 Challenger Drive

Alameda CA 94501

Roslin, Edinburgh

EH259PP Scotland

1010 Atlantic Avenue

Alameda CA 94501

101 Binney Street

Cambridge MA 02142

Roskildevej 12 C

P. O. Box 8299

Philadelphia PA 19101-8299

c/o Genzyme Corporation

Framingham MA 15 Pleasant St. Connector, P.O. Box 9322 01701

Archimedesweg 4 Archimedesweg 4 Cipalstreet 3

B-2440 Geel

Cipalstreet 3

B-2440 Geel

460 Point San Bruno Boulevard

South San Francisco CA 94080

Kornhamnstorg 53

Box 2077

9640 Medical Center Drive

Rockville MD 20850

9640 Medical Center Drive

Rockville MD 20850

322 East Main Street

Branford CT 06405

14 Cambridge Center

Cambridge MA 02142

38835

14 Cambridge Center

Cambridge MA 02124

2400 Boston Street

Baltimore MD 21224

800 Research Parkway

Suite 200

7000 Portage Road

Kalamazoo MI 49001-0199

7000 Portage Road

Kalamazoo MI 49001-0199

Gate 11, Victoria Dr.

Adelaide SA 5000

41 Morres Road

P. O. Box 4011

P.O. Box 2400

Glen Allen VA 23058-2400

87 CambridgePark Drive

Cambridge MA 02140

1201 Eastlake Avenue East

Seattle WA 98102

One Amgen Center Dr.

Thousand Oaks CA 91320-1799

One Technology Place

Rockland MA 02370

3333 Vaca Valley Parkway

Vacaville CA 95688

Unit 14, Bridgecourt Office Park

Dublin

One Health Plaza

East Hanover NJ 07936-1080

1 DNA Way

South San Francisco CA 94080

300 Technology Square

Cambridge MA 02139

389-A Nichol Hill Road

Franklin TN 37067

Roskildevej 12C

3400 Hillerod

Roskildevej 12C

3400 Hillerod

Oklahoma City OK 73104

Frazer PA 19355

38268

3400 West Bayshore Road

Palo Alto CA 94303

1 DNA Way

South San Francisco CA 94080-4990

14 Cambridge Center

Cambridge MA 02142

14 Cambridge Center

Cambridge MA 02142

14 Cambridge Center

Cambridge MA 02142

14 Cambridge Center

Cambridge MA 02142

14 Cambridge Center

Cambridge MA 02142

300 Technology Square

Cambridge MA 02139

One Amgen Center Dr.

Thousand Oaks CA 91320-1799

1301 Harbor Bay Parkway

Alameda CA 94502

190 Bath Road

Berkshire S11 3XE

866 Malcolm Road

Burlingame CA 94010

866 Malcolm Road

Burlingame CA 94010

938 Clopper Road

Gaithersburg MD 20878

3200 Walnut Street

Boulder CO 80301

3200 Walnut Street

Boulder CO 80301

14 Cambridge Center

Cambridge MA 02142

460 Point San Bruno Boulevard

South San Francisco CA 94080

9020 SW Washington Square Road

Suite 380

2929 Seventh Street

Berkeley CA 94710

9 Great Valley Parkway

Malvern PA 19355

Tigard, OR 972234332

146 Flanders Drive

Hillsborough NJ 08876

725 Chesterbrook Blvd.

Wayne PA 19087-5677

Via Campo di Pile

67100 - L'Aquila

3260 Whipple Road

Union City CA 94587-1217

Bldg 10/Rm 2N236 DASS/PPCS/NIDCR/NIH

10 Convent Drive

35 West Watkins Mill Road

Gaithersburg MD 20878

35 West Watkins Mill Road

Gaithersburg MD 20878

41 Moores Road

Frazer PA 19355

9200 Indian Creek Parkway

Building 9, Suite 200

Overland Park KS 66210

One Mountain Road

P.O. Box 9322

Framingham MA 01701-9322

Bethesda MD 20892

35082

Abbott Laboratories, Dept. 389, Bldg. J45 200 Abbott Park Rd.

Abbott Park IL 600646135

Abbott Laboratories, Dept. 389, Bldg. J45 200 Abbott Park Rd.

Abbott Park IL 600646133

1100 Olive Way, Suite 100

Seattle WA 98101

4851 Lake Brooke Drive

Glen Allen VA 23060

Unit 14

Walkinstown Avenue

104 Chancellor Matheson Road

Winnipeg, Manitoba

3300 Hyland Avenue

Costa Mesa CA 92626

2000 Galloping Hill Road

Kenilworth NJ 07033

148 Sidney Street

Cambridge MA 02139

148 Sidney Street

Cambridge MA 02139

148 Sidney Street

Cambridge MA 02139

Dublin 12

34782

37831

148 Sidney Street

Cambridge MA 02139

148 Sidney Street

Cambridge MA 02139

148 Sidney Street

Cambridge MA 02139

P.O. Box 16529

Columbus OH 43216

235 East 42nd Street

New York NY 10017

201 Elliott Avenue West

Suite 150

P.O. Box 9627

Kansas City MO 64134

32653

P.O. Box 9627

Kansas City MO 64134

34485

P.O. Box 9627

Mail Station: H3-M2516

Kansas City MO 64134-0627

P.O. Box 9627

Mail Station: H3-M2516

Kansas City MO 64134-0627

P.O. Box 9627

Mail Station: H3-M2516

Kansas City MO 64134-0627

1700 Perimeter Park Drive

Morrisville NC 27560

111 Rock Road

Horsham PA 19044-2310

500 Arcola Road

PO Box 5096

500 Arcola Road, P.O. Box 1200

Collegeville PA 19426

8700 Mason-Montgomery Road

Mason OH 08807

1 DNA Way

South San Francisco CA 94080-4990

1 DNA Way

South San Francisco CA 94080-4990

1 DNA Way, MS 242

South San Francisco CA 94080-4990

5200 Research Place

San Diego CA 92122

126 East Lincoln Ave.

Rahway NJ 07065

33961

Seattle WA 98119

35968

Collegeville PA 19426-0800

35045

35760

780 Memorial Drive

Cambridge MA 02139

One Broadway

Cambridge MA 02142

7000 Portage Road

Kalamazoo MI 49001-0199

7327 Oak Ridge Highway

Knoxville TN 37931

Byk-Gulden StraBe 2

78467 Konstanz

220 Park avenue

Florham Park NJ 07932

4140 Dublin Blvd.

Suite 200

55 Challenger Road

Ridgefield NJ 07660

9640 Medical Center Dr.

Rockville MD 20850

12419 198th Drive, NE

Woodinville WA 98072

90 Gold Street, 6N

New York NY 10038

1550 Sawgrass Corporate Parkway

Sunrise FL 33323

51 University Street

Seattle WA 98101

33302

51 University Street

Seattle WA 98101

34957

Corpus Christi House

Godmanchester, Cambridgeshire PE29 2HY

600 College Road East

Princeton NJ 08540

1250 S. Collegeville Road

Collegeville PA 19426-0989

Dublin CA 94568

35894

33967

666 Sherbrooke Street West, Suite 1400 Montreal, Quebec

2000 Galloping Hill Rd.

Kenilworth NJ 07033

190 Agronomy Road (UBC)

Suite 405

Vancouver, BC V6T 1Z3

650 Cathill Rd.

Sellersville PA 18960

1885 33rd Street

Boulder CO 80301

777 South Harbor Island Boulevard

Tampa FL 33602

32664

100 Longwater Circle

Norwell MA 02061

35699

One Technology Place

Rockland MA 02370

One Technology Place

Rockland MA 02370

1668 Valtec Lane

Boulder CO 80306

21823 30th Drive Southeast

Bothell WA 98021

21823 30th Drive, Southeast

Bothell WA 98021

21823 30th Drive Southeast

Bothell WA 98021

1000 Central Street, Suite 615

Evanston IL 60201

1000 Central Street, Suite 615

Evanston IL 60201

1690 Russell Road

PO Box 1766

One MedImmune Way

Gaithersburg 20878

6700 West Loop South

Suite 400

One Franklin Plaza

Philadelphia PA 19101

1564 33rd Street, NW

Washington DC 20007

9902 Indian Creek Lane

El Cajon CA 92021

University of Florida

P.O. Box 100277

Gainesville FL 32610

University of Florida

P.O. Box 100277

Gainesville FL 32610

3260 Whipple Rd.

Union City CA 94587-1217

Paoli PA 19301

Bellaire TX 77401

University Of Florida

P.O. Box 100277

Gainesville FL 32610

2032 Corte del Nogal

Suite 120

Carlsbad CA 92011

3260 Whipple Rd.

Union City CA 94587-0700

877 Main Street, Suite 402

Boise ID 83702

8260 E. Gelding Drive #104

Scottsdale AZ 85260

8260 East Gelding Drive

Scottsdale AZ 85260

8260 E. Gelding Drive

Scottsdale AZ 85260

26072 Merit Circle

Laguna Hills CA 92653

8125 North Hayden Road

Scottsdaale AZ 85258

75 5th Street, NW.

Atlanta GA 30308

8125 N. Hayden Road

Scottsdale AZ 85258

1300 Gould Dr.

Gainesville GA 30504

8125 N. Hayden Road

Scottsdale AZ 85258

8125 N. Hayden Road

Scottsdale AZ 85258

84 Park Avenue

P. O. Box 968

35185

Flemington NJ 08822

Commander, Us Army Medical Materiel Dev. Activity Ft. Detrick MD 21702

4620 Creekstone Drive

Suite 200

2500 Millbrook Drive

Buffalo Grove IL 60089

26072 Merit Circle

Laguna Hills CA 92653

Durham NC 27703

P. O. Box 2142

WA 6018

P. O. Box 2142

Osbourne Park, Western Australia 6017

119 Fourth Ave.

Needham MA 02494-2725

119 Fourth Avenue

Needham Heights MA 02194

5885 Trinity Parkway

Suite 350

400 Rella Boulevard, Suite 201

Suffern NY 10901

1950 Lake Park Drive

Smyrna GA 30080

460 Point San Bruno Boulevard

South San Francisco CA 94080

460 Point San Bruno Boulevard

South San Francisco CA 94080

Lilly Corporate Center

Indianapolis IN 46285

100 College Road West

Princeton NJ 08540

100 Overlook Center

Suite 200

Lilly Corporate Center

Indianapolis IN 46285

100 Overlook Center

Suite 200

70 Wood Avenue, South

Iselin NJ 08830

7000 Portage Road

Kalamazoo MI 49001-0199

One Technology Place

Rockland MA 02370

460 Point San Bruno Boulevard

South San Francisco CA 94080

One Technology Place

Rockland MA 02370

100 Longwater Circle

Norwell MA 02061

2958101

1 DNA Way

South San Francisco CA 94080-4990

2958101

Centreville VA 20120

31337

39233

Princeton NJ 08540

35429

Princeton NJ 08540

35734

31337

Princeton NJ 08540

2958101

100 Overlook Center

Suite 200

One Technology Place

Roackland MA 02370

One Technology Place

Rockland MA 02370

7000 Portage Rd.

0633-298-113

7000 Portage Road

Kalamazoo MI 49001

37097

Lilly Corporate Center

Indianapolis IN 46285

31844

460 Point San Bruno Boulevard

South San Francisco CA 94080

35779

460 Point San Bruno Boulevard

South San Francisco CA 94080

34290

100 Longwater Circle

Norwell MA 02061

35300

460 Point San Bruno Boulevard

South San Francisco CA 94080

35429

400 Morgan Lane

West Haven CT 06516

400 Morgan Lane

New Haven CT 06516

400 Morgan Lane

West Haven CT 06516

5 Research Parkway

P.O. Box 5100

300 Fairfield Road

Wayne NJ 07470

300 Fairfield Road

Wayne NJ 07470

500 Arcola Road

Collegeville PA 19426

5110 Campus Drive

Plymouth Meeting PA 19462

3260 Hillview Avenue

Palo Alto CA 94394

3260 Hillview Avenue

Palo Alto CA 94304

9 Great Valley Parkway

Malvern PA 19355

37956

Kalamazoo MI 4900136697 0199

38706 Wallingford CT 06492

33907

9 Great Valley Parkway

Malvern PA 19355

12276 Wilkins Avenue

Rockville MD 20852

5, Nahum Hafzadi St.

Jerusalem 95484

Avenue du Vent des Dames - Z.l. les Paluds

13685 Aubagne

Avenue du Vent des Dames - Z.l. les Paluds

13685 Aubagne

4 Plympton Street

Woburn MA 01801

230 East Grand Ave.

South San Francisco CA 94080-4811

230 East Grand Ave.

South San Francisco CA 94080-4811

90 Park Avenue

New York NY 10016-1389

90 Park Avenue

New York NY 10016-1389

P.O. Box 419056

Saint Louis MO 63141-9056

14555 Avion at Lakeside

Chantilly VA 20151

100 Banks Avenue

Rockville Centre NY 11570

100 Banks Avenue

Rockville Centre NY 11570

227-15 North Conduit Avenue

Laurelton NY 11413

37 Cleveland Lane

P.O. Box 5290

4560 Horton Street

Emeryville CA 94608

70 Wood Avenue, South

Iselin NJ 08830

Parke-Davis Pharmaceutical Research Division

2800 Plymouth Road

1576 Sweet Home Road

Amherst NY 14228

2516 Stockton Boulevard

Sacramento CA 95817

35788

32499

34544

Princeton NJ 08540

Ann Arbor MI 481052430

2958101

201, 1204 Kensington Road, N.W.

Calgary, Alberta

41 Seyon Street

Waltham MA 02453

15500 Gallaudet Ave.

Silver Spring MD 20905-4176

15500 Gallaudet Ave.

Silver Spring MD 20905-4176

15500 Gallaudet Ave.

Silver Spring MD 20905-4176

1550 Gallaudet Ave.

Silver Spring MD 20905-4176

15500 Gallaudet Ave.

Silver Spring MD 20905-4176

15500 Gallaudet Ave.

Silver Spring MD 20905-4176

37561

15500 Gallaudet Ave.

Silver Spring MD 20905-4176

37350

15500 Gallaudet Ave.

Silver Spring MD 20905-4176

37350

205 Buffalo Avenue

Freeport NY 11520

Three Parkway North

Deerfield IL 60015-2548

3 Parkway North Center

Deerfield IL 60015

Lilly Corporate Center

Indianapolis IN 46285

2355 Waukegan Road

Deerfield IL 60015

8 Greenway Plaza

Houston TX 77046

8 Greenway Plaza

Suite 910

Houston TX 77046

Greenway Plaza

Suite 910

Houston TX 77046

8 Greenway Plaza

Suite 910

Houston TX 77046

7000 Shoreline Court

Suite 370

South San Francisco CA 94080

9 Parker

Irvine CA 92618-1605

38805

2161 Delaware Aenue

Santa Cruz CA 95060

1205 Kent Ave.

West Lafayette IN 47906

410 West Harrison

Seattle WA 98119-4007

300 American Road

Morris Plains NJ 07950

300 American Road

Morris Plains NJ 07950

300 American Road

Morris Plains NJ 07950

300 American Road

Morris Plains NJ 07950

124 Mount Auburn Street

Suite 200 North

210 Carnegie Center

Princeton NJ 08540

67 Winston Churchill Avenue

Brussels

United Drug House

Dublin

2000 Galloping Hill Rd.

Kenilworth NJ 07033

2000 Galloping Hill Road

Kenilworth NJ 07033

2000 Galloping Hill Rd.

Kenilworth NJ 07033

2000 Galloping Hill Rd.

Kenilworth NJ 07033

36383

P. O. Box 8299

Phildelphia PA 19101-8299

39232

5 Research Parkway

P.O. Box 5100

500 Arcola Road

Collegeville PA 19426

27 Maple St.

Milford MA 01757

Cambridge MA 02138

38426

Wallingford CT 06492 33799

32134

400 Rella Boulevard, Suite 201

Suffern NY 10901

3 Werner Way

Round Valley Executive Center

901 Sawyer Rd.

Marietta GA 30062

Research Park

417 Wakara Way

1990 N.W. 44th Street

Pompano Beach FL 33064

70 Wood Avenue South

Iselin NJ 08830

1825 K Street NW

Suite 1475

Washington DC 20006

1825 K Street, NW

Suite 1475

Washington DC 20006

371 Bel Marin Blvd.

Novato CA 94949

University of Vermont

84 Beartown Rd.

9 Great valley Parkway

Malvern PA 19355-1304

Josef-Engert-Str. 9

93053 Regensberg

Technoiparkstrasse 1

Zurich

86 Morris Avenue

Summit NJ 07901

11800 Baltimore Avenue, Suite 113

Beltsville MD 20705

P.O. Box 4914

7 Powder Horn Drive

7 Powder Horn Dr.

Warren NJ 07059

718 Bradford Avenue

Westfield NJ 07090

718 Bradford Avenue

Westfield NJ 07090

718 Bradford Avenue

Westfield NJ 07090

P.O. Box 4914

7 Powder Horn Drive

Lebanon NJ 08833

Salt Lake City UT 84108

Underhill VT 05489

Warren NJ 07059

Warren NJ 07059

11800 Baltimore Avenue, Suite 113

Beltsville MD 20705

11800 Baltimore Avenue, Suite 113

Beltsville MD 20705

7 Powder Horn Dr.

Warren NJ 07059

P.O. Box 4914

7 Powder Horn Srive

86 Morris Avenue

Summit NJ 07901

7 Powder Horn Dr.

Warren NJ 07059

7 Powder Horn Dr.

Warren NJ 07059

24128 Bergamo, 64/B Broseta Street

Bergamo

901 Mariner's Island Blvd

San Mateo CA 94404

901 Mariner's Island Blvd.

San Mateo CA 94404-1593

901 Mariner's Island Blvd.

San Mateo CA 94404-1593

901 Mariner's Blvd., Suite 205

San Mateo CA 94404-1593

3 Bethesda Metro Center

Suite 700

500 Iolab Drive

Claremont CA 91711

One Kendall Square

Cambridge MA 02139-1562

One Kendall Square

Cambridge MA 02139

9 Great Valley Parkway

PO Box 3026

3300 Hyland Avenue

Costa Mesa CA 92626

120 Constitution Drive

Menlo Park CA 94025

336 Bollay Drive

Goleta CA 93117

Warren NJ 07059

35992

38862

Bethesda MD 20814

36129

Malvern PA 19355

1607 N. Douglas Ave.

Arlington Heights IL 60004

38124

1607 N. Douglas Avenue

Arlington Heights IL 60004

38124

The University of Texas Health Scienc Center at Da

5323 Harry Hines Boulevard

920 U.S. Highway 202

Raritan NJ 08869

11 Great Valley Parkway

P. O. Box 3026

48 Bis, Rue des Belles-Feuilles

75116 Paris

Domino's Farms

24 Frank Lloyd Wright Drive

Domino's Farms, Lobby L

Ann Arbor MI 48105

Parc Technologique Du Canal-4

31521 Ramonville Saint Agne

800 Gateway Boulevard

South San Francisco CA 94080

Drug Regulatory Affairs

One Health Plaza

East Hanover NJ 07936-1080

Drug Regulatory Affairs

One Health Plaza

East Hanover NJ 07936-1080

9 Great Valley Parkway

Malvern PA 19355

Route 202, P.O. Box 300

Raritan NJ 08869-0602

3030 Callan Road

San Diego CA 92121

P.O. Box 65

02101 Espoo

P.O. Box 65

02101 ESPOO

2301 Renaissance Blv.

P.O. Box 61540

920 US Highway 202

Raritan NJ 08869

Dallas TX 75235

32366

Malvern PA 19355

Ann Arbor MI 48105

35786

37131

35579 King of Prussia PA 19406-2772

37799

920 U S Highway 202

Raritan NJ 08869

146 Medinah Drive

Blue Bell PA 19422-3212

146 Medinah Drive

Blue Bell PA 19422-3212

P.O. Box 16529

Columbus OH 43216

P.O. Box 16529

Columbus OH 43216

P.O. Box 16529

Columbus OH 43216

Level 31, ABN AMRO Tower

88 Phillip Street

3055 Patrick Henry Drive

Santa Clara CA 95054

Roslin, Edinburgh

EH259PP Scotland

1 DNA Way

South San Francisco CA 94080-4990

Fehlandtstrasse 3

D-20354 Hamburg

68 T.W. Alexander Dr.

P.O. Box 14186

340 Kingsland Street

Nutley NJ 07110

3 Forbes Road

Lexington MA 02421

3 Forbes Road

Lexington MA 02421

34 Sherrill Rd.

Marshfield MA 02050

6200 Seaforth Street

Baltimore MD 21224-6506

Division Of Merck And Company

West Point PA 19486

Institute of Metabolic Disease

3812 Elm Street

One MedImmune Way

Gaithersburg MD 20878

One MedImmune Way

Gaithersburg MD 20878

31776

Sydney, N.S.W. 2000

Research Triangle Park NC 27709

37397

35025

31359

Dallas TX 75226

West Conshohocken PA 19428

One Tower Bridge

100 Front Street, Suite 400

One MedImmune Way

Gaithersburg MD 20878

One MedImmune Way

Gaithersburg MD 20878

One MedImmune Way

Gaithersburg MD 20878

7929 Westpark Drive, Suite 400

Mclean VA 22102

P.O. Box 8050, Station F

Edmonton, Alberta

P.O. Box 8050

Edmonton, Alberta

P.O. Box 8050

Edmonton, Alberta

P.O. Box 8050

Edmonton, Alberta

Box 19255

Johnston RI 02919

5710 Hoover Blvd

Tampa FL 33634

10505 Roselle Street

San Diego CA 92121

Scheijdelveweg 2

P.O. Box 43

100 Longwater Circle

Norwell MA 02061

100 Longwater Circle

Norwell MA 02061

University of Utah Health Sciences Center

50 North Medical Drive, Room 4R240

3, avenue GeorgeV

75008 Paris

Division of Tishcon Corp

P. O. Box 331

Westbury NY 11590

30 New York Avenue

P.O. Box 331

Westbury NY 11590

30 New York Ave.

PO Box 331

Westbury NY 11590

Grillparzerstrasse 10B

81675 Munich

3214ZG Zuidland

Salt Lake City UT 84132-0001

34320

2 Venture Plaza

Irvine CA 92618

4222 Emperor Boulevard, Suite 470

Durham NC 27703

4222 Emperor Boulevard, Suite 470

Durham NC 27703

100 Longwater Circle

Norwell MA 02061

One Technology Place

Rockland MA 02370

500 Iolab Drive

Claremont CA 91711

59 Route 10

East Hanover NJ 07936-1080

597 Laurier Blvd

Mount St. Hilaire Quebec H7L 4S3

35774

104 Chancellor Matheson Road

Winnipeg, ManitobaR3T 5Y3

2958101

64 Thomas Johnson Drive

Frederick MD 21702

38401

78 Fallon Drive

North Haven CT 06473

10901 Granada Lane

Suite 101

Paul-Ehrlich Str. 42-44

D-60596 Frankfurt am Main

103 Carnegie Center, Suite 102

Princeton NJ 08540

1800 Concord Pike

Wilmington DE 19830-8355

666 Sherbrooke Street West 1400 666 Sherbrooke Street West

Suite

31673

Leawood KS 66211

36063

Montreal, Quebec, Suite 1400

Montreal, Quebec H3A 1E7

17 rue des Terreaux

CH-1000 Lausanne 9

17 rue des Terreaux

CH-1000 Lausanne 9

666 Sherbrooke Street West, Suite 1400 Montreal, Quebec 155 Innovation Drive

R3T 5Y3

14 Cambridge Center

Cambridge MA 02142

14 Cambridge Center

Cambridge MA 02142

200 Westpark Corporate Center

4364 South Alston Avenue

105 Digital Drive

Novato CA 94949

Four Parkway North

Deerfield IL 60015

Division of ICI Americas

Wilmington DE 19897

Division of ICI Americas

Wilmington DE 19897

7000 Shoreline Court

South San Francisco CA 94080

7100 Woodbine Avenue, Suite 215

Markham, ON L3R 5J2

Hillcrest

San Diego CA 92103-8450

Merck & Co., Inc.

P. O. Box 2000, RY 32-605

P. O. Box 2000, RY 32-605

Rahway NJ 07065-0900

P. O. Box 2000, RY 32-605

Rahway NJ 07065-0900

99 Hayden Ave.

Lexington MA 02421-7995

4 rue Pierre Fontaine

300 American Rd.

Morris Plains NJ 07950

Durham NC 277132280

Rahway NJ 070650900

38996

340 Kingsland Street

Nutley NJ 07110

33774

NIH, Executive Plaza North, Room 7-18 Bethesda MD 20892

5 Moore Drive

Research Triangle Park NC 27709

31855

5 Moore Drive

Research Triangle Park NC 27709

31855

1510 Delp Drive

Kulpsville PA 19443

35458

59 Route 10

East Hanover NJ 07936-1080

37123

12264 El Camino Real

San Diego CA 02130

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