TCM Materia Medica

MATERIA MEDICA OF reM HUIYANCAI

2006 Edition

.

Table of Content GENERAL

PRINCIPLES

PREPARATION

CHAPTER

9

OF HERBS

1

13

HERB THAT RELEASE

THE EXTERIOR

...............•............................................•......•........•.•..•...•..••..•...••.••...•.••.•...••..•.....................................................••.....••..............•..•.•.•......•.......•.......................•..•..••....•

14

SECTlON] WARM.

15 ACRID

HERBS

THAT RELEASE

THE ExTERIOR

15

15

Ephedra Stem Ma Huang Cinnamon Twig GUlZhi Peril/a Leaf. Zi Su Ye

IWPt

15 ,

l!tL

,

" "

16

"

16

17

~;j';,"t

w

or 1~lId) Jing Jie Ji~ Ledebourie/la (root, siler) Fang Feng 'Ji 9\ NOlopterygillln Root Qiang Huo ;li'; i;li Chinej'e Lovage ROOI,Liguslicum GaoBen ~ Chinese Angelica 1~oot B 1£ Bai Zh,

17

••• w.w

Schizonepela

18 18

19

_

*

19 20 20 21 21 22 22

_._

Root "

Chinese Wild Ginger, Asantn, Xi Xin Jill Fresh Ginger J?hizome Sheng Jiang AromaticMadder, Elsholtzia

_

$

23

"

23 24 24 , 25

h ••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••

't ~

25

'i!i iiW .. Xiang Rn Magnolia Flower Xin Yi Hua >;; ~ 1t Cockleburr Fruit, Xanthillm

26 n ••••• _••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••

h •••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••

_••

_

26 27

••••••••••••••••••••••••••

1); J+ 1'

CangEr Zi

27

SECTlON2 COLD.

28

ACRID

HERBS

THAT RELEASE

THE EXTERIOR

28

Field Mint, Mentha Bo He flII W Great Burdock Fntit, Arctium

'I'

_

'll' Niu Bang Zi Cicada Moulting " Chan Tui ~ ~JI. While Mlliberry Leqf Sang Ye !ill. Vilex Fruit

"

28 28 29

"

1' "."

,.

29 30 30

h •••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••

31

~I·

n ••••••••••••••••••••••••••••••••••••••••••••••••••••

Man ling Zi ill: Jitl 1' Chrysanthemum Flower Ju Hua oro 1t Prepared Soybean Dan Dou Chi Wi 5'i. Kudzu Root, Pueraria Ge Gen 11\ IlL

n •••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••

n •••••••••••••••••••••••••••

31 32

n •••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••

32 n ••••••••••••••••••••••••••••••••••••••••••••••••••

33

, ••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••

33 d •••••••••••••••••••••

n ••••

_

Thorowax ROOI, =1''''''"1 Chai Hu i\Il

36 36

Bugbane Rhizome, Black Cohosh Rhizome, CimictfUga Jt Sheng Ma

_

37 37

,

n~

CHAPTERII SECTION HERBs

HERBS THAT CLEAR

HEAT.

38

I THAT DRAIN

39 FIRE

Gypsum Shi Gao

39

1'i~

_

~Q £1 Zhi Mu Cape Jasmine Fruit, Gardenia ZhiZi ;!JB1' Lophatherum Stein and Leaves DanZhu Ye LoluS Plumule un ••••• II 'L.' Lian Xin Reed Rhizolne

n •••••••

39 39

n •••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••

40 41 41 42 42 43 43 44

, n ••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••

, •••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••

1klt"t.. n

_

pilL

Lu Gen Se?fheal Spike, Prunella Xia Ku Cao Jil.1~1if. Foetid Cassia Seeds, Cassia Jue Ming Zi tli: 'JJ Celosia Seeds QingXiangZi 111fIi Bear Gallbladder II!! Xiong Dan

, _

,., ,

44 45 45 46 46 47 47 48 48

"

_

,

1'

n ••••• _••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••

1'

ii~

SECTION HERBS

34 34 35 35

ilI<

n •••••••••••••••••••

: ••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••

2

49

THAT COOL THE BLOOD

Rhinoceros Horn XiIiao

49

_

49

Jlj!. ilJ..

49

Water Buffalo HOJ71 ...•.....••••.•.•.....••••..••..••••••.•..•.....•...••....•.•.......•.....•.•..•..•••...•••••.•••.•.•..•.•....•.•..........•.•••...•..••...•••.••.•••••.•••.•••.....•••.••.•••••••..•...•.•.•....••.....•.•...•..•.•......•.•.•...•••.•..•..........•.••.... Shut Niu Jiao 71IOOgm)

© 2006 --- Hui-Yun

Cai --- All Rights Reserved

207

Rhizome of Woolly Grass, Imllerata, White Grass Bai Mao Gen

B ~

*N

Pharmaceutical Name: Rhizoma Imperatae Cylindricae Properties: sweet, cold Channels Entel-ed: Lung, Stomach, Small Intestine, Bladder Actions and Clinical Applications: 1. Cools the Blood, and Stops Bleeding For reckless movement of Hot blood: nose bleed, bloody urine; vomiting or coughing of blood 2.

Clears Heat and Promotes urination a) Heat strangury b) Edema and jaundice due to Damp-Heat

3.

Clears Heat from the Lmlgs and Stomach a) Thirst (febrile disease and diabetes with excessive thirst), or vomiting due to Stomach-Heat b) Wheezing due to Lmlg-Heat

Dosage and Administration: 9-24g. Pharmacological Actions: a) Major Ingredients: Cylindrine, arundoin, femenol, potassium, calcium b) Actions: • The aqueous infusion exerts a significant diuretic effect and lowers blood pressure in experimental animals • Hemostatic effect: Shortens clotting time and bleeding time, decreases the permeability of blood vessels, and promotes the formation of fibrinogen • Antibiotic effect: Has a strong in vitro inhibitory effect against staphylococcus aureus and bacillus dysenteriae Notes: Bai Mao Gen (white grass) has the advantage of promoting urination without damaging Yin

© 2006 --- Hui-Yan Cai --- All Rights Reserved

208

Section 2 Herbs that Invigol'ate the Blood

Szechuan Lovage Root, Cnidium Chuan Xiong

]J!13

Pharmaceutical Name: Radix Ligustici Chuanxiong Properties: acrid, warm Channels Entel'ed: Liver, Gallbladder, Pericardium Actions and Clinical Applications: I. Invigorates Blood, Promotes Qi Movement, and Regulates the menstruation a) OB/GYN disorder: dysmenorrhea, amenorrhea, difficult labor, lochioschesis, retention of placenta, still birth due to Blood and Qi Stagnation b) Internal medical problems: Qi and Blood Stagnation of angina pectoris, chest pain, and abdominal pain, anemia, bone spur, spinal bone hyperplasia, thromboagitis, obliterans, and leukocytopenia c) Trauma 2.

Expels Wind and Relieves Pain: a) Frequently used for headache due to various causes (Wind Cold, Wind Heat and Blood Deficiency or Blood stasis, depending on the combination with other herbs), the herbs can move the Qi upward and Stops pain b) Used for a variety of skin problems caused by Wind c) Bi syndrome (painful obstruction syndrome) various Bi patterns, especially Cold Bi

Dosage and Administration: 3-9g. (may use up to 15g.) Pharmacological Actions: a) Major Ingredients: Tetramethylpyrazine (Clman Xing Zine), ferulice acid, cnidilide, sedanonic acid, 4-hydroxy-3-buryl-phathalide xingol) b)

(Chuan

Actions: • Cardiovascular effect: The active component, tetramethylprazine, can dilate the coronary artery and increase the coronary flow; water or alcoholic infusion of Chuan Xiong can lower blood pressure • Effect on smooth muscle: The alkaloids (ferulic acid and cnidilide) are antispasmodics, but a very small amount of a 10% solution of Chuan Xiong can stimulate pregnant rabbit uterus specimens, while large amounts stop contractile effects • •

Anti-biotic effect: Inhibits the growth of bacteria and dermatomycoses Antiplatelet and anticoagulant effect

Notes: Caution with excessive menstrual bleeding and pregnancy

© 2006 --- Hui- Yan Cai --- All Rights Reserved

209

Spatholobus or Millettia Root and Vine JiXueTeng Pharmaceutical Name: Radix et Caulis Jixueteng Properties: bitter, sweet, warm Channels Entered: Heart, Liver, Spleen Actions and Clinical AI}plications: 1.

Reinforces the Blood and Promotes Blood Circulation: For Blood Deficiency with Blood Stasis syndrome: OB/GYN disorder (irregular menses, amenorrhea with abdominal pain; dysmenorrhea); vertigo; aplastic anemia or leukopenia caused by radiation therapy or chemotherapy

2.

Tonifies the Blood, Invigorates the Channels and Relaxes the sinews: For Blood Deficiency with or without Stasis syndrome: Low back/knee extremities, sequela windstroke paralysis

pain, Wind-Damp

Bi with joint soreness, weak

Dosage and Administration: 9-15g.

(up to 30g. in severe case)

Pharmacological Actions: a)

M1Uor Ingredients:

b)

Actions: • Anti-inflammatory: arthritis in rats

Oral administration

of the decoction inhibits the development

offormaldehyde-induced

•

Central nervous system effect: Intraperitoneal rats

injection of the decoction, exerts sedative and hypnotic effects on

•

Cardiovascular effect: Intravenous injection in dogs, can dilate coronary and femoral arteries, decrease peripheral resistance ~l1ldincrease the volume of blood flow

• •

Inhibits the aggregation of thrombocytes induced by collagen Phosphate metabolism effect: Increases the rate of phosphate metabolism

in the kidneys and uterus in mice

Notes: Contraindicated

during pregnancy

© 2006 --- Hui- Y an Cai --- All Rights Reserved

210

Corydalis Rhizome Van Hu Suo Pharmaceutical Name: Rhizoma Corydalis Yanhusuo Properties: acrid, bitter, warm Channels Entered: Heart, Liver, Lung, Stomach Actions and Clinical Applications: I. Invigorates the Blood, Promotes Qi Circulation and Relieves Pain: Any kind of pain (combined with other appropriate herbs): OB/GYN disorder, especially dysmenorrhea; pain in the chest; epigastrium abdomen; hernial disorder; headache; backache; painful obstructed syndrome, trauma, etc. 2.

Recently use for angina pectoris, peptic ulcer and neuralgia

Dosage and Administration: 4.5-] 2g. (powder: 1.5-3g.) Phannacological Actions: a) Major Ingredients: Corydaline, dl- tetrahydropalmatine, b)

corydalis L.

Actions: • Analgesic effect: The components d-corydaline and dl-tetrahydropalmatine are analgesics, the combined alkaloid effect are 40% as great as morphine, but safe and with less side effect, also as a muscle relaxant • Gastrointestinal efTect: Decreasing the secretion of gastric acid and the amount of pepsin • Hypnotic and sedative effect: corydaline and dl-tetrahydropalmatine have a hypnotic and sedative effect in many animals • •

Cardiovascular effect: decrease resistance of blood flow and increase blood perfution to coronary arteries, Decrease oxygen consumption of the cardiac muscle and increase the contractility of hear Adrenocortical effect: increase adrenal glands and increase the secretion

Notes: ]. 2.

Contraindicated with pregnancy Vinegar-fry to enhance the blood-invigorating

and pain-relieving

Nan Sha Shen) • Cardiovascular effect: 1% water extraction shows a cardiotonic effect on frog • Hematology effect: the decoction of Sha Shen inhibits the red blood cell aggregation • 1:2 of water extraction has a expectorant effect (Nan Sha Shen > Bei Sha Shen)

Notes: a. Incompatible with Li Lu (Rz.et Rx. Veratri) b. Bei Sha Shen is growing up in North China c. Nan Sha Shen (Radix Adenophorae) is growing in South China ,and less potent in Nourishing and Generating fluids, but better to stop coughing

102006 ••- Hui-Yan Cai --- All Rights Reserved

280

Asparagus Tuber Tian Men Dong Pharmaceutical Name: Tuber Asparagi Cochinchinensis Properties: sweet, bitter, very cold Channels Entered: Kidney, Lung Actions and Clinical Applications: I. Nourishes Kidney, Clears Lung lleat, and Stops Coughing For Yin Deficiency with Heat signs in upper burner: dry mouth/throat/coughing, that is difficult to expectorate 2.

3.

Moistens Lungs, Nourishes Kidneys and Generates Fluids a) Wasting-thirsting disorder (Upper or Lower Jiao) b) Constipation with afternoon tidal fever due to Lung/Kidney c) Constipation due to dry intestines Recently used for chronic pharyngolaryngitis, lymphoma

thick blood-streaked

or thick sputum

Yin Deficiency

whooping cough, mammary hyperplasia, breast cancer, malignent

Dosage and Administration: 6-15g. Pharmacological Actions: a) Major Ingredients: Asparagine, 5-methoxy-methylfurfural,

smilagenin, neo-ketose, l3-sitosterol

b) Actions: • Asparamide is an expectorant, antitussive, and antiasthmatic • Antineoplastic effect: preparation ofTian Men Dong has an inhibitory effect in vitro against the deoxygenase of acute lymphocytic, acute monocytic, and chronic granulocytic leukemias • Antibiotic effect: decoction ofTian Men Dong have an inhibitory effect in vitro against streptococcus, pneumoniae, hemolytic streptococcus, staphylococcus aureus, and bacillus subtilis group Notes:

(Qi2(l()6

m

Hui-Yan

Cni

mAil

Righls

Reserved

281

Ophiollogon Tuber MaiMen Dong Pharmaceutical Name: Tuber Ophiopogonis Japonnici Properties: sweet, very bitter, very cold Channels Entered: Heart, Lung, Stomach Actions and Clinical Applications: 1. Enriches Yin, Moistens the Lung and Stops Coughing For LLmgYin Deficiency or Lung Dryness with dry cough, thick sputum that is difficult to expectorate, or coughing up blood 2.

Nourishes Stomach Yin and Generates Fluids a) Stomach Yin Deficiency or post-febrile disease with consumption of fluids: dry throat and mouth, thirst, constipation b) Wasting-thirst disorder (Upper or Middle Jiao)

3.

Nourishes Heart Yin, Clears Hearts and Reduces vexation For Heart Yin Deficiency or Heat in Ying Level (warm-febrile disease) with irritability, insomnia, palpitation and fever worsen at night,

4.

Moistens the intestines and Promotes the bowel movement For constipation due to Yin Deficiency or damage to body fluids

5.

Recently use for angina pectoris

Dosage and Administration: 6-15g.

Pharmacological Actions: a) Major Ingredients: Opiopogonin A, B, C, D; ruscogenin, B-sitosterod, stigmasterol, OTS (ophiopogon total saponins) b) Actions: • Relieves leucopenia in mice induced by cyclophosphamide and radiation sickness in dogs • Increases anoxia tolerance in animals under atmospheric pressure • Effect on Cardiovascular: improve the myocardial cell recovery from myocardial infraction, increase coronary flow and improve myocardial contractility in guinea-pigs, also has cardic arrhythmic effets • Endocrine effect decrease the level of serum glucose level, improve recovery of islets of langehans and increase glycogen storage level in rabbits • Antibiotic effect: the powder of Mai Men Dong has an inhibitory against typhoid bacillus, staphylococcus albus, bacillus coli • Effect on immune system: increases the weight gain of spleen and promotes phagocytosis in rats Notes: Wine-fry to reduce cold properties or use for angina pectoris

© 2006 --- Hui- Y an Cai --- All Rights Reserved

282

Dendrobium Shi Hu

Phm-maceutical Name: Herba Dendrobii Pmperties: sweet, slightly salty, bland, cold Channels Entered: Kidney, Stomach Actions and Clinical Applications: ]. Enriches Stomach Yin, and Generates the Fluids: For Stomach Yin Deficiency or Damage fluids from febrile disease with severe thirst, parched mouth, or stomachache, dry heaves, mirror red tongue 2.

Nourishes Kidney Yin, and Clears Deficiency Heat For Kidney Yin Deficiency with Empty Heat: vexation, fever etc.

3.

Strengthens the low back, and Brightens the vision For dim vision, low back pain, or weakness of the legs due to Kidney Yin Deficiency

Dosage and Administration: 6-ISg.

Pharmacological Actions: a) Major Ingredients: Dendrobine, dendranime, nobilonine, dendroxine, dendrin, 6-hydroxydendroxine b) Actions: • The active ingredient, dendrobine, lowers blood pressure; is also an antipyretic and analgesic • Cardiovascular effect: the infusion is cardio-inhibitory, and lower the blood pressure • Effect on smooth muscle: low dosage stimulates while high dosage inhibited the intestine movement of rabbits in vitro Notes: Contraindicated

for excess heat, early stages febrile disease, abdominal distention with a thick and greasy tongue

~J 2006 --- Hui- YJIl C'ai --- All Rights Reserved

283

Polygonatum, Polygonatum Officinalis Yu Zhu (Wei Rui) Pharmaceutical Name: Rhizoma Polygonati Odorati PrOl)erties: sweet, slightly cold Channels Entered: Lung, Stomach Actions and Clinical Applications: 1. Nourishes the Lmlg and Stomach and Moistens Dryness: a) Lnng/Stomach Yin Deficiency, or dry-heat with cough, dry throat, and mouth b) Waisting-thirsting with intense hnnger, constipation c) Post-febrile disease with thirst 2.

Extinguishes wind and Softens the sinews: a) Spasms of the sinews/muscles, dizziness due to Yin Deficiency with Internal Wind b) Exterior Wind-Heat with Yin Deficiency (non-cloying and dose not retain exogenic evil)

3.

Recently use for hyperlipemia, angina pectoris, and congestive heart failure

Dosage and Administration: 9-15g. Pharmacological Actions: a) Major Ingredients: Convallamarin, convallarin, quercital, polygonatin,etc. b) Actions: • Antibiotic effect: the decoction inhibits the growth of staphylococcus aureus. Proteus and Bacillus coli in a concentration of 1:320, 1:160, 1:20 respectively in vitro • Cardiovascular effect: small doses ofYu Zhu decoctions have a positive inotropic and chronotropic effect on frog, while large doses have a strong inhibitory effect • Effect on blood pressure: the decoction ofYu Zhu shows a temporarily effect that lowers blood pressure • Endocrine effect: oral or il1iections in animals, reduces blood lipids and serum glucose • Effect of Smooth Muscle: mild stimulating on uterus in mice, also after stimulating follow by inhibiting effet on smooth muscle of intestine Notes: Use raw to clear heat; steam (until black) to tonify

© 2006 --- Hui- Y an Cai --- All Rights Reserved

284

Lily Bulb Bai He

Pharmaceutical Name: Bulbus Lilii Properties: sweet, slightly bitter, sl ightly cold Channels Entered: Heart, Lung Actions and Clinical Applications: 1. Moistens the Lungs, Clears Heat, and Stops Coughing: For dry Lungs or Lung Heat Cough, or Coughing blood 2.

Clears Heart and Calms the Spirit: For Yin Deficiency or post febrile disease, damage to fluids with vexation, insomnia, hysteria, palpitation etc.

Dosage and Administ."ation: 9-30g. Pharmacological Actions: a) Major Ingredients: Alkaloids, colchcine, starch, protein, lipids, sugars, organic acid, Ca+, Mg+, K+, iron, zince, AI(Aluminium) b) Actions: • Effect on the respiratory: the decoction can relieve coughing induced by ammonia in mice, and relieves asthma induced by histamine in toads • Hypnotic and sedative effect: the decoctions of Bai He, cause a deep sleep and prolongs sleep time in mice • The decoctions of Bai He show an anoxia tolerance effect on rats Notes: Contraindication

for patients with middle jioa deficientcy,and

iD 2006

h.

HlIi· Yan eai

h'

cough due to wind cold or phlegm

All Rights

Reserved

285

Mulberry Mistletoe Stems, Loranthus Sang Ji Sheng

~

*~

Pharmaceutical Name: Ramulus Sangiisheng Properties: bitter, neutral Channels Entered: Kidney, Liver Actions and Clinical Applications: 1. Tonifies Liver and Kidney, Strengthens the sinews and bones, and Expels Wind-Dampness a) Wind-Damp Bi syndrome with Liver and Kidney Deficiency b) Wei (atrophy) S}l1drome 2.

Nourishes the Blood, and Calms the fetus For restless fetus or uterine bleeding during pregnancy

3.

Lowers blood pressure For hypertension due to Liver and Kidney Deficiency

4.

Nourishes the Blood and Benefits the skin For dry or scaly skin from Blood Deficiency

5.

Recently used for angina pectoris and arrhythmia

Dosage and Administration: 9-30g. Pharmacological Actions: a) Major Ingredients: avicullarin, oleanolic acid, p-myrin, mesoinositol, lupeol, P-sitosterol, myristic acid, flavones, quercetin, arabinose b) Actions: • Cardiovascular effect: avicullarin and intravenous injection of alcohol extraction resulting in lowering blood pressure in anesthetized dogs and cats, also dilates coronary arteries and slows heart rate • Counteracts the stimulating effect of caffeine • Diuretic effect: avicullarin has demonstrated a diuretic effect in animals • Anti-viral effect: the decoction of San Ji Sheng has an inhibitory effect in vitro against ECHO and Coxsackie vrruses • C.N.S. suppressant effect • Anticoagulant effect: inhibiting platelet aggregation and prevent the formation of embolus Notes: 1. Wine-fry for Wind-Damp Bi 2. Large overdoses in animals have resulted in vomiting, diarrhea, or death

© 2006 --- Hui- Y an Cai --- All Rights Reserved

286

Eclipta Han Lian Cao Pharmaceutical Name: Herba Ecliptae Prostratae Properties: sweet, sour, cool Channels Entered: Kidney, Liver Actions and Clinical Applications: I. Nourishes the Liver and Kidney For Liver and Kidney Yin Deficiency with dizziness, tinnitus, blurred vision, alopecia, or premature graying of the hair, teeth looseness etc. 2.

Cools the Blood and Stops bleeding For many kinds of bleeding due to Yin Deficiency with blood heat (vomiting or coughing up blood, nosebleed, blood in stool, especially blood urine). Use fresh for open wounds

3.

Recently used for rice-fried dermatitis, allergic dermatitis or eczema, genital damp itch, coronary heart disease

Dosage and Administ."ation: 9-15g. (fresh up to 30g.) Pharmacological Actions: a) Major Ingredients: saponins, including ec1iptine, and £-telihienylmethanol,

thiophene derivates, wedelolactone

b) Actions: • Promotes lymphocyte-blastogenesis • Hematology effect: anticoagulative effect, promotes tibrinolysis, and reduces bleeding time • Effect on liver function: the decoctions of Hen Lian Cao prevents liver cell damage from poisoning • Cardiovascular effect: increases coronary flow Notes:

«)

2006

nO

Hui- Yan Cai

on

All Rights Reserved

287

PI-ivet Fruit, Ligustrum Nu Zhen Zi

Pharmaceutical Name: Fructus Ligustri Lucidi Properties: bitter, sweet, neutral Channels Entered: Kidney, Liver Actions and Clinical Applications: I. Nourishes Liver/Kidney and Improves vision a) Liver and Kidney Deficiency with dizziness, blurred vision, timritus, soreness of lower back or knees, premature gray hair or seborrhea alopecia b) Diminished vision, central retinitis, or early cataracts due to liver I kidney Deficiency 2.

Enriches Liver and Kidney Yin, Clears Deficiency Heat For Deficiency Heat with insomnia, Five-Fire-Heart, etc.

3.

Recently used for angina pectoris, hyperlipemia,

neurasthenia,

leukocytopenia,

viral hepatitis, diabetes

Dosage and Administration: 4.5-15g. Pharmacological Actions: a) M~or Ingredients: Nuzhenide, olemopein, b)

4-hydroxy-

B-phenylethyl-

B-dalucoside,

oleanolic acid, betulin, salidroside,

ursolic acid, mtin

Actions: • The component oleanolic acid can prevent and relieve cyclophosphamide-induced leukocytopenia in mice • Injection of extraction Nu Zhen Zi enhances coronary flow and inhibits myocardial constriction in rabbits in vitro • Metabolism effect: oleanolic acid, lowers the level of blood lipid, increases HDL, decreases LDL • Effect on Liver: oleanolic acid reduces SGPT, promotes recovery of the liver cells • Anti-cancer: 50% decoctions ofNu Zhen Zi inhibits uterine cervic 14 (u-14), Sl80 • Anti- diabetic effect •

Hematological

effet: stimulates the production

of blood cell in mice

Notes:

© 2006 --- Hui- Yan Cai --- All Rights Reserved

288

Black Sesame Seeds Hei Zhi Ma Pharmaceutical Name: Semen Sesami Indici Properties: sweet, neutral Channels Entered: Kidney, Liver Actions and Clinical Applications: I. Nourishes Liver and Kidney, Tonifies the Blood, and Extinguishes Wind For Liver, Kidney and Blood Deficiency with headache, dizziness, blurred vision, tinnitus, numbness 2.

Moistens the Intestines and Promotes Bowel movement For constipation due to dry intestines or Blood Deficiency

Dosage and Adminish'ation: 9-30g. Phar'macological Actions: a) Major Ingredients: Lignans, sesamin, sesandin, sesamol, planteose, sesomose, vitamin E, cytochrome C, 48% oleic acid, 37% linoleic acid b) Actions: • Metabolism effect: the ingredient, linoleic acid, significantly decreases the serum cholesterone • Endocrine effect: oral administration of Hei Zhi Ma in rats reduces serum glucose levels and increases the storage ofliver glycogen, but very large doses reduces stored glycogen • Effect on gastrointestinal tract: I-Iei Zhi Ma has a significant laxative effect • Hematologic effect: injection of the oil ofHei Zhi Ma, increases the hematocrit in rates Notes: 1. Dry-hied or steamed prior to use 2.Using caution for the patients who are Spleen Qi deficiency with diarrhea