These results are from the Open Notebook Science Solubility Challenge as of October 1, 2013 A compilation of the results in book form can be obtained from Nature Precedings Solubility of acetaminophen in organic solvents. Total Number of Results: 89 Total Number of Solvents: 47 CSID: 70309 Solvent
Ave. (M) Hits
SD
Link to Detailed Results
1. 1,4-dioxane
0.232
2
0.168 Solubility of acetaminophen in 1,4-dioxane is 0.232 M
2. 1-butanol
0.472
2
0.021 Solubility of acetaminophen in 1-butanol is 0.472 M
3. 1-heptanol
0.196
2
0.015 Solubility of acetaminophen in 1-heptanol is 0.196 M
4. 1-hexanol
0.264
2
0.012 Solubility of acetaminophen in 1-hexanol is 0.264 M
5. 1-octanol
0.150
4
0.011 Solubility of acetaminophen in 1-octanol is 0.150 M
6. 1-pentanol
0.449
3
0.165 Solubility of acetaminophen in 1-pentanol is 0.449 M
7. 1-propanol
0.692
2
0.051 Solubility of acetaminophen in 1-propanol is 0.692 M
8. 1-tert-butoxy-2-propanol 0.282
2
0.000 Solubility of acetaminophen in 1-tert-butoxy-2-propanol is 0.282 M
9. 2-butoxyethanol
0.469
2
0.000 Solubility of acetaminophen in 2-butoxyethanol is 0.469 M
10. 2-ethoxyethanol
1.236
2
0.001 Solubility of acetaminophen in 2-ethoxyethanol is 1.236 M
11. 2-isopropoxyethanol
0.760
2
0.000 Solubility of acetaminophen in 2-isopropoxyethanol is 0.760 M
12. 2-propanol
0.695
2
0.046 Solubility of acetaminophen in 2-propanol is 0.695 M
13. 2-propoxyethanol
0.698
2
0.000 Solubility of acetaminophen in 2-propoxyethanol is 0.698 M
14. 3-methoxy-1-butanol
0.582
2
0.000 Solubility of acetaminophen in 3-methoxy-1-butanol is 0.582 M
15. DMF
5.016
1
0.000 Solubility of acetaminophen in DMF is 5.016 M
16. N-methyl-2-pyrrolidone
5.045
1
0.000 Solubility of acetaminophen in N-methyl-2-pyrrolidone is 5.045 M
17. PEG400
0.865
1
0.000 Solubility of acetaminophen in PEG400 is 0.865 M
18. PEG400/water(25:75)vol 0.358
1
0.000 Solubility of acetaminophen in PEG400/water(25:75)vol is 0.358 M
19. PEG400/water(50:50)vol 0.946
1
0.000 Solubility of acetaminophen in PEG400/water(50:50)vol is 0.946 M
20. PEG400/water(75:25)vol 1.469
1
0.000 Solubility of acetaminophen in PEG400/water(75:25)vol is 1.469 M
21. THF
0.925
2
0.064 Solubility of acetaminophen in THF is 0.925 M
22. acetone
0.532
2
0.006 Solubility of acetaminophen in acetone is 0.532 M
23. acetonitrile
0.144
4
0.005 Solubility of acetaminophen in acetonitrile is 0.144 M
24. benzene
0.001
1
0.000 Solubility of acetaminophen in benzene is 0.001 M
25. butanone
0.368
2
0.009 Solubility of acetaminophen in butanone is 0.368 M
26. carbon tetrachloride
0.005
2
0.006 Solubility of acetaminophen in carbon tetrachloride is 0.005 M
27. chloroform
0.007
4
0.006 Solubility of acetaminophen in chloroform is 0.007 M
28. cyclohexane
0.0001
2
0.000 Solubility of acetaminophen in cyclohexane is 0.0001 M
29. dichloromethane
0.003
2
0.000 Solubility of acetaminophen in dichloromethane is 0.003 M
30. ethanol
1.659
3
0.977 Solubility of acetaminophen in ethanol is 1.659 M
31. ethanol/water(10:90)vol 0.137
1
0.000 Solubility of acetaminophen in ethanol/water(10:90)vol is 0.137 M
32. ethanol/water(20:80)vol 0.221
1
0.000 Solubility of acetaminophen in ethanol/water(20:80)vol is 0.221 M
33. ethanol/water(30:70)vol 0.422
1
0.000 Solubility of acetaminophen in ethanol/water(30:70)vol is 0.422 M
0.000 Solubility of acetaminophen in ethanol/water(40:60)vol is 0.644 M
35. ethanol/water(50:50)vol 0.939
1
0.000 Solubility of acetaminophen in ethanol/water(50:50)vol is 0.939 M
36. ethanol/water(60:40)vol 1.206
1
0.000 Solubility of acetaminophen in ethanol/water(60:40)vol is 1.206 M
37. ethanol/water(70:30)vol 1.322
1
0.000 Solubility of acetaminophen in ethanol/water(70:30)vol is 1.322 M
38. ethanol/water(80:20)vol 1.393
1
0.000 Solubility of acetaminophen in ethanol/water(80:20)vol is 1.393 M
39. ethanol/water(90:10)vol 1.295
1
0.000 Solubility of acetaminophen in ethanol/water(90:10)vol is 1.295 M
40. ethyl acetate
0.082
3
0.038 Solubility of acetaminophen in ethyl acetate is 0.082 M
41. ethylene glycol
1.297
3
0.520 Solubility of acetaminophen in ethylene glycol is 1.297 M
42. formamide
2.749
1
0.000 Solubility of acetaminophen in formamide is 2.749 M
43. hexane
0.000
1
0.000 Solubility of acetaminophen in hexane is 0.000 M
44. isopropyl myristate
0.003
1
0.000 Solubility of acetaminophen in isopropyl myristate is 0.003 M
45. methanol
2.628
3
1.271 Solubility of acetaminophen in methanol is 2.628 M
46. toluene
0.002
2
0.001 Solubility of acetaminophen in toluene is 0.002 M
47. water
0.091
5
0.005 Solubility of acetaminophen in water is 0.091 M
Permalink: http://lxsrv7.oru.edu/~alang/onsc/solubility/allsolvents.php?solute=acetaminophen predicted solubility in 80+ solvents | melting point of acetaminophen
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