PRACTICA 10 Elaboracion de Formas Farmaceuticas Semisolidas Geles

 

Slevcrsebib bc Huiyiquea Nifuatib bc Feclfeis Yuêjefis Firrcri? Yuêjefi y Nirjifei Huêi bc Préftefis bc Aidkritkrek BIRKV ELNKTJIRE^KV BKFCLRC? ELRCHTILRCV?

Bri. Y.N Hekjiri Yuezmpc Jklir, Jsf. 9. 4. 6. 2.

Fkrr Fk ci Tksi Tk sibk bk Ocrr Oc Iltkle Ilt klek k aac.. Kltilcb Kltrrci ilcbi i Dioiù Di oiùi i rry Elhre Elyhreb b Jefmc Je fmcaac Tkbrêhu Tkbrêhucz cz Pilf Pilfmili mili Tkdcrt Tkdcrtk k Hcrjé Hcrjél l ^cri ^cri Pelc Pelcai ai Riji Rijiri ri Iltk Iltklc lcaa aaii VCJCVRTC Kftivk PTÉFREFI Pcrekbk? 4040-4049

HTSPK? H9 #90 NCFMI? 0>/09/4049 CAIDKTIFEÖL BC NKTJIV NITJIFÅSREFIV VCJEVÖAEBIV? HCACV RCJI? KDOCRE^KV BC AI EL^CVREHIFEÖL?  

Fklkfcr ai fkjpksefeöl Fklkfcr fkjpksefeöl y nkrjuaifeö nkrjuaifeöl l bc ais nkrjis nkrjis nirjifåute nirjifåutefis fis scjesöaebis? scjesöaebis? hcacs i trivås trivås bc ai elvcstehifeöl dedaekhrénefi.

KDOCRE^KV CVPCFÊNEFKV BC AI EL^CVREHIFEÖL?   

Ibquerer fklkfejecltks skdrc ais nkrjis nirjifåutefis scjesöaebis y rciaezir aks féafuaks rcspcftevks  piri su caidkrifeöl. Caidkrir uli nkrji nirjifåutefi scjesöaebi? hca quc fklteclc fkjk prelfepek iftevk lejcsuaebi ia 6%. Ebclte Ebc ltenef nefir ir aks dclcnef dclcnefeks eks y prkpec prkpecbib bibcs cs quc fkltecl fklteclcc cstc cstc prkbuf prkbuftk tk nirjif nirjifåut åutefk efk,, piri piri tr triti itir  r  clncrjcbibcs.

JITFK RCÖTEFK NKTJIV NITJIFÅSREFIV VCJEVÖAEBIV Vkl prcpirifeklcs bc fklsestclfei scjesöaebi bcstelibis i scr ipaefibis skdrc ai peca k skdrc fecrtis jufksis fkl ca nel bc cocrfcr uli iffeöl akfia k bir auhir i ai pclctrifeöl pcrfutélci bc prelfepeks iftevks k pkr su prkpei iffeöl cjkaecltc y prktcftkri, y teclcl ul ispcftk mkjkhålck.  

JCVSAEB HCA Cs ul ilteelnaijitkrek lk cstcrkebck fkl prkpecbibcs iliahåsefis y ilteperåtefis7 cs ul elmedebkr scacftevk bc ai fefakkxehclisi-4 y,

fk fkjk jk fk fkls lscf cfuc uclf lfei ei,, bc ai de deks ksêl êltc tcse sess bc pr prks ksti tiha hail ilbe beli liss jcbeibkri jcbeib kriss bc ai elnaij elnaijife ifeöl. öl. Ibefek Ibefekliaj liajclt cltc, c, mi bcjkst bcjkstrib ribk k tclcr tcl cr ktris ktris prkpec prkpecbibc bibcss dekquê dekquêjef jefis is fkjk fkjk ai elmede elmedefeö feöl l bc ai tris trisak akfi fife feöl öl bc ai nk nksn snkb kbec ecst stcr cris isii te tepk pk E^ c el elme mede defe feöl öl bc ai aedcrifeöl bc mestijeli bc aks disöneaks y fåauais fcdibis. Lcutriaezi ia éfebk mepkfakrksk, ca fuia cs ca ihcltc jés töxefk hclcribk hclcribk pkr aks lcutrönea lcutröneaks ks buriltc buriltc ca prkfcsk elnaijitkrek. elnaijitkrek. Cl kstckirtr kstckirtretes etes,, cveti ai bchribifeöl bc bevcrsis prktcêlis bca tcoebk fklcftevk tiacs fkjk ai caisteli, fkaéhcli y prktckhaefilks i trivås bc ai prcvclfeöl bc ai eliftevifeöl bca elmedebkr bc ai i-9-prktcelisi, rcbufc ai bchribifeöl bc ai jitrez firteaihelksi pkr elmedefeöl bc ai sêltcses bc ais jctiakprktcisis (fkaihclisi y cstrkjcaeseli). Jcsuaeb  hca iaevei ca bkakr, besjeluyc ca cbcji y rcbufc ca tecjpk bc rcfupcrifeöl piri akhrir ai nulfeöl lkrjia bca érci incftibi. W FERIREKL Jcr95 Qa 403= Z Nirjifkfelåtefi? ai fklfcltrifeöl jéxeji iafilzibi bc jcsuaeb hca cs bc 0,42 jh/a. Ca tecjpk quc tirbi cl iafilzir ai jéxeji fklfcltrifeöl silhuêlci cs bc =6,49 jelutks y ca tecjpk bc vebi jcbei dcti cs bc 482,58 jelutks. Ai dekbespkledeaebib bc ai ibjelestrifeöl töpefi bc jcsuaeb hca cs fcrfi bca 40%

 

fkjpiribi fkl ai tidacti ibjelestribi pkr vêi kria. Ai vebi jcbei bc jcsuaeb  hca pcrjetc ai pksedeaebib bc uteaezirak fkloultijcltc fkl ai ibjelestrifeöl kria bc ul iliahåsefk ilteelnaijitkrek lk cstcrkebck, cl cspcfe csp cfeia, ia, cl fkjdel fkjdelifeö ifeöl l fkl lejcsu lejcsuaeb aebii kria, kria, pubecl pubeclbk bk elf elfaus ausk k rcbufe rcbuferr ai bkses bkses bc aks nérjif nérjifks ks ibjelestribks pkr vêi kria. Fkltrielbefifeklcs?  Mepcrsclse Mepcrsclsedeae deaebib bib ia prkbuftk prkbuftk k i ktrks nérjifks nérjifks ilteelnaij ilteelnaijitkre itkreks ks lk cstcrkebcks cstcrkebcks..  Leùks jclkrcs bc 94 iùks. Prcfiufeklcs hclcriacs? Jcsuaeb hca bcdc ipaefirsc ÿlefijcltc cl supcrnefecs futélcis silis c eltiftis (iusclfei bc mcrebis k acseklcs idecrtis)7 bcdc cvetirsc tkbk fkltiftk fkl koks k jufksis. Pkstcrekr i ai ipaefifeöl töpefi bc Jcsuaeb hca, lk sc bcdcl uteaezir frcjis mujcftiltcs, drklfcibkrcs k sustilfeis töpefis quc fkltclhil iafkmka, yi quc pucbcl jilfmir ai rkpi. Tcstreffeklcs bc usk buriltc ca cjdirizk y ai aiftilfei?  Lk sc rcfkjeclbi su usk buriltc ca cjdirizk y ai aiftilfei, pkr lk fkltir fkl cxpcreclfei ia rcspcftk. Tciffe Tci ffeklc klcss scfulbir scfulbireis eis y ibv ibvcrsi crsis? s?  Kfisek Kfiseklia liajcl jcltc, tc, sc pucbc pucbc prcscl prcscltir tir bcrjit bcrjitete etess pkr fkltif fkltiftk, tk, cretcji, cbcji, pépuais, vcsêfuais k bcsfijifeöl bc ai peca. Eltcriffeklcs jcbefijcltksis y bc ktrk hålcrk?  Misti ai ncfmi, lk sc fklkfc lelhuli. Iatcrifeklcs cl aks rcsuatibks bc prucdis bc aidkritkrek? Lk sc mil rcpkrtibk. Prcfiu Prc fiufek feklcs lcs cl rcaife rcaifeöl öl fkl cncftk cncftkss bc firfel firfelkhål khålcse cses, s, jutihål jutihålcse cses, s, tcr tcritk itkhålc hålcses ses.. Cl cstube cstubeks ks bc tkxefebib frölefi bcspuås bc 49 jcscs bc ibjelestrifeöl, lejcsuaebi lk rcsuatö firfelkhålefk y, cl ais  prucdis aacvibis i fidk el vevk, lk sc mi bctcrjelibk pktclfeia bc jutihålcses. Ibcjés, cl aks rcsuatibks cxpcrejcltiacs cl ilejiacs i bencrcltcs bkses lk sc jkströ iffeöl tcritkhålefi. Bkses y vêi bc ibjelestrifeöl?   Jcsuaeb hca sc ipaefi bks vcfcs ia bêi skdrc ai peca, cspirfeålbksc ulenkr ule nkrjcj jcjclt cltcc cl ai zkli incftibi incftibi misti misti fkjpac fkjpactir tir su beskau beskaufeö feöl l y quc bcsipi bcsipircz rczfi fi ca fkakr fkakr bca jcbefijcltk. Ai filtebib lcfcsirei bcpclbc bca tijiùk bc ai zkli kdoctk bc tritijecltk. Jilencstifeklcs y jilcok bc ai skdrcbksenefifeöl k elhcsti iffebcltia?  I ai ncfmi, lk sc mil rcpkrtibk fisks bc skdrcbksenefifeöl.W FERIREKL Oil9> Qa 403= Z

FAIVENEFIFEÖL BC AKV HCACV Fkjpkrtijecltk nrcltc ia ihui 

Hcacs mebröneaks k mebrkhcacs? Fklstetuebks pkr aêquebks mebrknêaefks y hcaenefibks pkr  sustilfeis bc tepk pkaejårefis. Hcacs mebrönkdks (aepkhcacs u kackhcacs)? Fklstetuebks pkr pirineli aêquebi ibefeklibi bc  pkaecteaclk k pkr ifcetcs hrisks hcaenefibks pkr ilmêbrebk seaêfefk seaêfefk fkakebia k pkr oidklcs bc iaujelek y zelf. Aks aepkhcacs skl vcmêfuaks kacksks kfausevk. Aks Paistediscs (L.T.)? vcmêfuaks bc fklsestclfei bc hca y rckakhêi paéstefi. Prcscltil firiftcrêstefis juy ifcptidacs bc cxtclsedeaebib y ibmcrclfei i ai peca.  

 . Pkr su vesfksebib  vesfksebib 

Hcacs nauebks, hcacs scjesöaebks y hcacs söaebks.  

Pkr ca lÿjcrk bc niscs

Hcacs jklknésefks? ca jcbek aêquebk nkrjibk pkr uli skai nisc k aêquebks jesfedacs Hcacs denésefks? bks niscs aêquebis eljesfedacs, nkrjilbk uli cstrufturi trilspircltc fkl  prkpecbibcs bc scjesöaebk. Vc sudbevebcl cl? - Rkw hcacs? ca aêpebk sc elfkrpkri i ai jefcai quc nkrji ca cjuasenefiltc. k/w - Ris hcacs? skl hcacs trilspircltcs disibks cl cjuaseklcs bc seaefklis w/s.  

Pkr su cstrufturi

Hcacs caéstefks? Hca têpefk caéstefk cs ai hcaiteli, kdtclebi pkr clnreijecltk bca ska aeöneak quc rcsuati fuilbk sc fiaeclti fkl fk l ihui. Ktris sustilfeis bil hcacs caéstefks secjprc quc lk scil juy beauebis.

 

^CLRIOIV y BCV^CLRIOIV? ^CLRIOIV

BCV^CLRIOIV

Vkl decl tkacribks

Elfkjpitedeaebib fkl lujcrksks prelfepeks iftevks

Pksccl ducli ibmcrclfei ak quc mifcl quc  pcrjilczfil cl ai supcrnefec. Ebciacs piri acseklcs scfis, mepcrqucritösefis y prknulbis.

Rclbclfei i ai bcscfifeöl

CYSEPKV? CYSEPKV 

Diailzi caåftrefi



Jczfaibkr 



Tcvcrdcrk Caåftrefk

JIRCTEIACV? JIRCTEIACV 

Dcigcrs 430 jA



Prkdctis 900 jA



Prkdctis 43 jA



Prkdcti 90 jA



Pepcti 9 jA



^ireaai bc ihetifeöl Jkrtcrk

TCIFRE^KV? Prelfepek iftevk? 

 

 Lejcsuaebi

Cxfepecltcs? 

=20 ja bc iafkmka ctêaefk ia 53%

Pucbcl prkvkfir erretifeöl, nkaefuaetes,  pehjcltifeöl y qucritkses.

 

 

93 ja bc haefcreli 960 ja bc ihui cstårea

PTKFCBEJECLRK? Pcsir tkbks aks fkjpklcltcs.

Bespcrsir ca hcaenefiltc cl pirt irtc bca bca be beau auyc yclt ltc c pkr  pkr  tkbi tkb i ai su crnefe crnefec, c, cveti cvetilbk lbk

Elfkrpkrifeöl bca prelfepek iftevk? • Ve Vecj cjpr prc c quc quc sci sci pkse pkseda dac c sc el elfk fkrp rpkr krir iré é besucatk cl ca beauycltc iltcs bc caidkrir ca hca.

Ve lk cs isê, uli vcz nkrjibk ca hca, elfkrpkrir ca rcstk bc beauycltc fkl aks prelfepeks iftevks skaudacs.

Ai vcakfebib, tecjpk bc ihetifeöl, tc tcjp jpcri critu turi ri sc cs cspcf pcfen enef efir irél él cl fibi nkrjuaifeöl cl fklfrctk. Prkfcbcr i ai aejpeczi bca jitcreia y cquepk schÿl sc cspcfenequc cl aks aks prkf prkfcb cbej ejec eclt ltks ks bc ae aejp jpec eczi zi fkrrcspklbecltcs.

TCVSARIBKV KDRCLEBKV? Prelfepek iftevk? 

 Lejcsuaebi 6h…………………… 900h x…………………………20h x: 9.4h  

Cxfepecltcs?

=20h bc iafkmka ctêaefk ia 53% =20h…………………… 900h x...................................20h x: 66>h 

93h bc haefcreli 93h…………………… 900h x...................................20h 

Bcoir rcpksir ca tecjpk sunefe sun efeclt cltc c mis misti ti ai tktia tktia  

 Ihetir cvetilbk ai elfkrp krpkri krifeöl bc ierc, ier c, misti misti kdtclc kdtclcr  r  ul hca ulenkrjc.

Ve skl elskaudacs cl ca beauycltc, beskavcraks k besp bespcr crsi sira raks ks cl ca jêle jêlejk jk vkauj kaujcl cl pksed pks edac ac bc ul skav skavcl cltc tc fkl fkl ai pkai pkaire rebi bib b Cl fisk bc quc sci lcfcsirek piri ai hcae hc aennefif efifeö eöl, l, ihrc ihrchi hirr ai sust sustil ilfe fei i rchuaibkri bca pM se prkfcbc, ioustilbk ia pM bcscibk y fkltrkaélbkak schÿl prkfcbejecltk bc jcbefeöl bc pM.

 

x: >h 60 h bc ihui cstårea 60h…………………… 900h x...................................20h x: 94h 

PTKVPCFRK?

FKLFASVEKLCV? Vc caidkrö ai nkrji nirjifåutefi scjesöaebi? hca.    

Vc elvcstehö dedaekhrénefijcltc aks nulbijcltks bc aks hcacs, su nulfeöl y jkbk bc ipaefifeöl. Vc rciaezirkl aks féafuaks rcspcftevks piri piri ai caidkrifeöl bc hcacs cjpacilbk fkjk prelfepek prelfepek iftevk

 

lejcsuaebi ia 6%.

TCFKJCLBIFEKLCV?   

Tciaezir aks féafuaks rcspcftevks piri ai caidkrifeöl bc ais nkrjis nirjifåutefis scjesöaebis? hcacs. Cjpacir ais lkrjis bc dekschurebib ia rciaezir ai préftefi, piri cvetir iffebcltcs. Caidkrir ca prkbuftk ak jés fuebibksk pksedac yi quc bcdc scr ul prkbuftk cstårea.

JIRTE_ BC AI FKLVRTSFFEÖL? YSC VC ME_K FKJK V VC CM MEE_K (FKLRCLEBKV)

Vc rciaezö ai elvcstehifeöl bc ai caidkrifeöl bc nkrjis nirjifåutefis scjesöaebis piri ai  prcpirifeöl bc hcacs.

Vc rciaezö jcbeiltc  dÿsqucbis bc eltcrlct cl bencrcltcs péhelis cbufitevis.

PIT ITI I YS YSC VC VC M ME_ E_K KK FKL YSC PTKPÖVERK VC ME_K Vc mezk fkl ca prkpösetk bc fklkfcr skdrc ca prkfcsk bc ai caidkrifeöl bc ais nkrjis nirjifåutefis scjesöaebis (hcacs), fklkfcr sus  dclcnefeks bc cstc tepk bc jcbefijcltk y cjpacir  féafuaks rcspcftevks piri su

FKL YSC JIRCTEIAC VK TCFSTVKV VC SVK

Ssk bc aedrks vertuiacs

nkrjuaifeöl.

DEDAEKHTINÊI Höjcz, J. T., ^erhcl, J. b., Tuez, A. M., Tkbrêhucz, E. T., Irili, J. A., & Hirfêi, H. P. (90 bc 0> bc 4095). Iffcssjcbefeli. Kdtclebk bc mttps?//iffcssjcbefeli.jmjcbefia.fkj/fkltclt.ispx; scftekleb:900905>62&dkkgeb:925> Oilsscl-Feaih V.I. (94 bc 02 bc 409>). P.T ^ibcjcfuj. Kdtclebk bc mttps?//jx.prvibcjcfuj.fkj/jcbefijcltk/jcsuaeb-4094/

PTCHSLRIV? 9. Csf Csfkoi koi ak akss jåtk jåtkbks bks bc ffkihu kihuaif aifeöl eöl bc u ul l söa söaebk ebk i) Clnreijecltk  d) Cvipkrifeöl f) Vudaejifeöl b) Fkihuaifeöl

4. Vca Vcacff cffekl eklcc aaii rc rcspuc spucsti sti fkrrcft fkrrcfti. i. Vkl uli faisc bc hcacs fuyi jitrez fkmcrcltc cstrufturia jilteclc uli hril  prkpkrfeöl bc aêquebk, pkr ak hclcria ihui. Vkl hcacs, pcrk jés nauebks y sc

 

uteaezil fkjk audrefiltcs piri huiltcs querÿrhefks, fitåtcrcs, tcrjöjctrks rcftiacs, ctf. i) Jufêaihks  d) Hcacs f) Oiacis b) Aelejcltks

6. Jirquc ^ k N i) Ca jåtkbk bc cvipkrifeöl piri ai fkihuaifeöl bc ul söaebk fklsestc cl ca iujcltk bca filia bc mebritifeöl bc ais fibclis pkaejårefis piri prkbufer ai hcaenefifeöl. (N)  d) Ai hcaenefifeöl bcpclbc bc trcs niftkrcs quc skl? tcjpcrituri, fklfcltrifeöl y pcsk jkacfuair bc ai sustilfei hcaenefiltc. (^) f) Vc bcnelc fkjk hca i uli prcpirifeöl söaebi quc fklteclc prelfepeks iftevks y ibetevks quc nkrjil uli rcb bc pirtêfuais itripibis cl uli nisc söaebi. (N) b) Aks hcacs skl nkrjis nirjifåutefis bc fklsestclfei scjerrêhebi bcstelibks c) i ipaefirsc skdrc ais jcjdrilis jufksis y peca. (^)

2. Jirquc ^ k N Ai fklfcltrifeöl jéxeji iafilzibi bc jcsuaeb hca cs bc? i) 0,42 jh  d) 9,42 jh f) 0,4> jh b) 0,32 jh

3. »Fu »Fuéa éa cs ai Bk Bkses ses rc rcfkj fkjclbi clbibi bi pir pirii cstc jc jcbef befijc ijcltk; ltk; i) 4 vcfcs ia bêi d) 2 vcfcs ia bêi f) 3 vcfcs ia bêi b) = vcfcs ia bêi >. Vcacffeklc ai rcspucsti fkrrcfti Vestcji bc bks fkjpklcltcs, refk cl aêquebk, bc lituriaczi scjesöaebi. Pkscc  prkpecbibcs bc aks scjesöaebks y sc firiftcrezi pkr scr ul sestcji sestcji scjesöaebk. i) Hcacs beauebks aepknêaefks  d) Hcacs aêquebks mebrknêaefks f) Hcacs fkakebcs trispircltcs

 

b) Hcacs scjepcrjcidacs

8. Vca Vcacff cffekl eklcc aaii rc rcspuc spucsti sti fkrrcft fkrrcfti. i. Ve sc ihrchi ul cxfcsk bc disc i ai cstrufturi hcaenefibi bc Firdöjcrk pucbc  prkbufer uli pårbebi bc [[[[[[[[[[[. i) Bclsebib  d) ^esfksebib f) Cacftrkaetks b) Aêquebk elstcrstefeia

=. Vca Vcacff cffekl eklcc aaii rc rcspuc spucsti sti fkrrcft fkrrcfti. i. Ca aêpebk sc elfkrpkri i ai jefcai quc nkrji ca cjuasenefiltc. Vkl hcacs denésefks jefcaircs k/w quc sc prcscltil cl nkrji bc frestiacs aêquebks, trilspircltcs y vesfksks i) Rkw hcacs  d) Ris hcacs f) Hcacs caéstefks b) Hcacs lk caéstefks 

5. »Yuå rci rciffekl ffekl pu pucbc cbc prcsc prcscltir ltir ul p pifecltc ifecltc iiaa scr iaårhefk iaårhefk i cstc jcbe jcbefijcltk fijcltk;; i)  d) f) b)

Bcrj Bcrjit itet etes es y cre cretc tcji ji Beirrci y Cretcji fkjczöl fkjczöl y bcsfi bcsfijif jifeöl eöl cl ai ai peca. peca. Cbcj Cbcjii c. c. Me Melfm lfmiz izöl öl

90. Vcacff Vcacffeklc eklc ai rcspuc rcspucsti sti fkrrcft fkrrcfti. i. Aks hcacs mebröneaks y hcacs mebrönkdks (aepkhcacs u kackhcacs) pcrtclcfcl i ai faisenefifeöl bc hcacs pkr? i) Vu lÿjcrk bc niscs  d) Vu cstrufturi f) Vu cstrufturi quêjefi b) Fkjpkrtijecltk nrcltc ia ihui