Physiology Cheat Sheet

 

Overview: Transmission: Transmiss ion: Gap junctions, synaptic, para/auto-crine/endocrine para/auto-crine/endocrine A!: P roprio,motor -12-20(70-120m/s) A!: Touch,pressure -5-12(30-70m/s) A": Motor spindle -3-6(15-30m/s) Ae: Pain,temp Ae: Pain,temp - 2-5(12-30m/s) B: Preganglionic B: Preganglionic 5.5Tall T-wave, K>6.5" K>6.5"conduction K>7 flat P waves 2’ atrial stun K>8QRS fusing

Glycine

ASys+30%Vol+ ASys +30%Vol+ Awave!Isovol Isovol,, Vent P>Atrial# P>Atrial# AV close, Cwave!Vent pressure >aortic(80mmHg)+Pul(10mm) pressure>aortic(80mmHg)+Pul(10 mm) AP valves open (125/25mmHg). 70-90mls ESVV=50mls. 70-90mls/HR EDVV=130mls!Propodiastole Propodiastole~0.04s ~0.04s!Isovol Isovol relax  relax  AP valves close V-wave!Diastole Diastole AV  AV open 70%fill

Tyrosine (hydroxylase) (hydroxylase) into axon Na:T channel#Tyrosine hydroxyl #DOPA#(decarboxylase)Dopamine[VMAT]#(hydroxylase) NORAD#Epinephrine Taken up by NET. Metab by MAO

LV output=O2 consumption/[Ao2-Vo2] consumption/[Ao2-Vo2] Frank Stirling = SV x VEDV Haemoglobin A=$ A=$2%2 Fetal=$ Fetal=$2&2 - binds 2,3BPG less avidly. avidly. Flow=P/R Renaulden endorphines>enkephalins>dyno kephalins>dynorphins rphins delta: enk>endo>dyn kappa: dyn>>endo>enk Dopamine D1#!cAMP D2#"cAMP

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Intrafusal=parallel Intrafusal=para llel to extrafusal AP#SM#T-tubles #Ca channel cisterns#DHPR(RyR cardiac) SR releases Ca#Binds TropC#Trop-I exposes Actin site#Actin&Mysoin crosslink#ADP released#movement#ATP binds#Recocks#repeat until Ca ReabsorbedSERCA#Trop-C releases Ca A band constant. Z lines move closer TypeI=SO(red),, TypeII=FOG,(Red)TypeIIb=FG(white) TypeI=SO(red) TypeII=FOG,(Red)TypeIIb=FG(white) Cardiac: Ca+calmodulin#MLCK#MLC binds to actin#XB T-system Skeletal muscle@AI, cardiac@Z IA=x3, GroupII=NC+SB,Dynamic$=Dynamic bags,static$=chain/static

Meissner=encapsulated Meissner=encap sulated dendrite-texture/slow vib rapid adapting Merkel=exp dendritic ending- sustained pressure/touch/Slow adapt Ruffini=exp dendritic-sustained pressure/slow adapt Pacinian=unmylinated Pacinian=unmylina ted deep pressure/fas pressure/fastt vib/Rapid adapt First pain = glutamate. Second pain = Substance P Warmth=C fibre cool=Ae Sensory:FasciculusGracilis/cuneatus#DC#medullaGCnuclei#X#medial leminiscus#VPostLnucleus Noiception:dorsalhorn#X#ascend Ventrolat Spinothalamic PthWay #VPL CSF - 60% prod choroid plexus. 90-150ml vol. 550ml per day Na=Na,K4.6=2.9,Mg1.7=2.4,Ca5.0=2.5,Glu92=61,AA2.3=0.8, Spinal cord: Autoreg(MAP60-150),Co2 linear(20-80),Hypoxia(