Pedia Notes Compilation MKDose

MKD COMPUTATION Weight x mkd x preparation = mL per dose Example: 12kg x 10mg x 5ml/120mg = 5mL per dose * If per day, divided total (mL) by the number of divided doses Dose x preparation x frequency weight

Empirical dose 6 months 6 mos – 2 y/o 2-6 y/o 6-9 y/o 9-12 y/o

= mkd * mkd = mk dose

PARACETAMOL Drops = Wt move 1 dec. point to the left Age 1 2 3 4 5 6

Wt 10 kg 12 14 16 18 20

* mkD = mk Day * C = capsule D = drops N = nebule S = syrup/suspension T = tablet

1 drop 1 teaspoon 1 tablespoon 1 wineglass 1 glassful 1 grain 1 pint 1 quart 1 ounce 1 kg 1 lb

= 1/20 ml = 5 ml = 15 ml = 60 ml = 2 ounces = 250 ml = 8 ounces = 60 mg = 500 ml = 1000 ml = 30 ml = 2.2lbs = 0.45359 kg

V = vial Sup = suppository Sac = sachet

¼ tsp ½ tsp 1 tsp 1½ tsp 2 tsp

Aspirin

ANALGESIC & ANTI-PYRETIC 60-80 mkD

T: 80mg, 100mg, 325mg

Indomethacin

st

RHD: 100 mkD (1 2 weeks) 75 mkD (4 weeks) Anti-inflammatory: 60-90 mkD Kawasaki: 80-100 mkD Q6 1-2 mkD x 3 (PDA)

C: 100mg

Ibuprofen

6-8 mkd Q6

D: 100mg/2.5ml S: 100mg/5ml, 200mg/5ml C: 200mg, 800mg

Mefenamic acid

6.5 mkd Q6

S: 50mg/5ml C: 250mg, 500mg

Meperidine Midazolam

6 mkD/ 0.5-1 mkD 0.2 mkd

T: 15mg V: 1mg/ml, 5mg/ml

Morphine

0.1-0.2 mkd Q6 (max 15mg)

T: 10mg, 30mg, 60mg, 100mg V: 10mg/ml

Nalbuphine

0.1-0.2 mkd IM/IV

V: 10mg/ml

Naproxen T: 275mg, 550mg

5-7 mkD Q8-Q12 (>2 y/o)

Paracetamol D: 100mg/ml S: 120mg/5ml, 250mg/5ml T: 80mg, 500mg V: 150mg/ml, 300mg/2ml Sup: 125mg, 250mg

10-15 mkd Q4

Cetirizine D: 2.5mg/ml, 10mg/ml S: 1mg/ml, 5mg/5ml T: 10mg

ANTI-HISTAMINES 6 mons-1y/o 1ml OD 1-2y/o

V: 10mg/ml

2.5mg BID 1ml OD or BID Promethazine HCl

2.5y/o

¼ tab BID or ½ tab OD 5ml OD or 2.5ml BID

Diphenhydramine S: 12.5mg/5ml C: 25mg, 50mg V: 50mg/ml

Hydroxyzine HCl

½ tab BID 10ml OD or 5ml BID

>12y/o 1 tab OD 1-2mg/kg IV (max 100mg/dose) 3-5 mkD PO 2-6y/o 2.5ml Q6/Q8 6-12y/o 5ml Q6/Q8 1-2 mkD Q12 PO

S: 2mg/ml T: 10mg, 25mg

Adult

25mg BID-QID

Loratadine

1-2y/o

2.5ml OD

S: 1mg/ml, 5mg/5ml T: 10mg

2-12y/o

30kg 10ml

>12y/o 6y/o

5ml TID

Chlorphenamine maleate S: 2mg/5ml T: 4mg

½ tab TID

Adult

1 tab TID or 2 tsp TID

IV/IM: 1ml OD 1mg/kg IM

V: 25mg/ml

Fexofenadine 6-12y/o

7-12y/o

T: 120mg, 180mg

120mg OD

Chlorphenamine maleate

COUGH & COLDS 0.2-0.3 mkD >12y/o

5ml TID or 1 tab TID

S: 2mg/5ml T: 4mg V: 10mg/ml

Ambroxol 30mg/tab

Syrup (15mg/5ml)

Infant drops (6mg/ml)

5-10y/o >10y/o

½ tab TID 1 tab TID

Erdosteine S: 175mg/5ml C: 300mg

15-19kg 20-30kg >30kg

5ml TID 5ml TID 10ml BID

Procaterol (Meptin)

6y/o

5ml or 25mcg/tab OD-BID

Adult 2-6y/o

20ml or 50mcg/tab OD-BID ½ - 1 tsp TID

Salbutamol + Guaifenesin

6-12y/o

1 tsp TID

>12y/o Children

10ml TID, 1 cap BID-TID 100mg BID-QID

2-5y/o >5-10y/o >10y/o

2.5ml BID 5ml BID-TID 10ml TID

Acetylcysteine

1-2y/o

0.5ml BID 1ml BID 1.25ml BID

Sach: 100mg, 200mg S: 100mg/5ml T(effervescent): 600mg

Adult

200mg BID-TID 600mg OD

Guaifenesin

6-12y/o

5ml TID-QID

Adult

5-10ml TID-QID 1-2caps TID-QID

Carbocisteine 2-3y/o 4-7y/o 8-12y/o

5ml TID 10ml TID 15ml TID

S: 100mg/5ml C: 200mg

Syrup (250mg/5ml)

2-3y/o 4-7y/o 8-12y/o

2.5ml TID 5ml TID 7.5ml TID

Drops (6.25mg/ml)

1-3mos0.25ml QID 4-6mos0.5ml QID 7-12mos 0.75ml QID 1-2y/o 1ml QID

Drops (50mg/ml)

12y/o)

V: 500mg, 1gm, 2gm

AmoxicillinClavulanic Acid

30-50 mkD Q8

30-50 mkD Q8 PO 50-100 mkD Q8 IV

(Co-Amoxiclav)

BETALACTAMS Penicillin 50-100 mkD Q6 Pen G Crystalline 100,000-200,000 ukD Q12 50,000-100,000 ukD Q8/Q12 (7days) Benzathine Penicillin Early syphilis: 500,000 u/K single dose

Sumapen

Syphilis: 50,000 u/K max dose 2.4M u/dose 50 mkD Q6

Phenoxymethyl penicillin 125/5 – 200,000 u/5ml 250/5 – 400,000 u/5ml

Ampicillin

Neonates

D: 125mg/1.25ml S: 125mg/5ml, 250mg/5ml C: 250mg, 500mg V: 125mg, 250mg, 500mg, 1gm

Meningitis:

Ampicillin-Sulbactam

100-200 mkD Q8 IV 1.5-12gm/day IV 50 mkD Q12 (1,200g (0-1wk) 1-4wks

Metronidazole S: 125mg/5ml T: 500mg V: 5mg/ml

20 mkd OD

30 mkd OD

Infant/Child: 20mkd Q8 PO 60 mkD Q8 1-3hr infusion 30-50 mkD Q8-Q12 PO 15 mkD LD, 7.5 mkD Q8

Prep: 50mg/vial Dose: 0.1 mkD, max 30-35mk in 3 weeks Should be properly covered Dilute 50mg vial + 10cc D5W to make a concentration of 5mg/10ml - then aspirate 1cc + 4cc D5W = 5mg/ml - then aspirate from the solution 1cc + 9cc D5W = 1mg/ml - then aspirate from the solution 1cc to make 0.1mg/ml Wt 1kg Test does: 0.1 mkd 1cc of solution + 19cc D5W x 30mins Day1 0.25mk: 2.5cc + 17.5cc D5W x 4hrs Day2 0.5mk: 5cc + 15cc D5W x 4hrs Day3 0.75mk: 7.5cc + 12.5cc D%W x 4hrs Day4 1mk: 10cc + 10cc D5W x 4hrs then OD

ANTI-VIRALS 10-20 mkD Q6

Acyclovir

Pyrantel Pamoate S: 200mg/5ml T: 200mg, 400mg, 800mg V: 250mg

Amantadine

Adult, children >2 y/o

200mg 5x daily

Children