Pathophysiology of Colon Cancer

Pathophysiology Modifiable Factor: - Occupation (Driver) - Dietary (Charcoal, Carbonated fluids) - Untreated diagnosed of Congenital Hernia to Indirect Inguinal Hernia - Lifestyle

Non-Modifiable Factor: Sex (Male) Age Genetic

Embroyonic Stage ( 20 weeks testis should descend) Failure of the testis to descend

Congenital Hernia

Untreated Hernia results to Intra-abdominal wall (containing membranes or muscles) becomes weakened

Relaxation of abdominal wall musculature

Thinning of the fascia Abnormal growth of Cells to the lining in the colon

Growth of Massess

Trauma to the lining of the ascending colon

Bleeding in the ascending colon

Inflammatory response

Redness

Blood vessel near the site of injury are dilated scrotum

Increased permeability of capillary

Plasma leak from blood stream into tissue

Heat

Insterstitial Filtration

WBC, enter tissue and begin to engulf bacteria

Swelling of tissue of scrotum Inflammation

Inflamed tissue reaches nociceptors

Stimulation of pain receptors

PAIN