PathoConceptMap AIDS

 

PATHOPHYSIOLOGY CONCEPT MAP EXPECTED DIAGNOSTIC TESTS

PATHOPHYSIOLOGY

Humn Immunode&'ien'y (irus !HI(" ) A'*uired Immunode&'ien'y Syndrome !AI+S" Etiolo%y, HI# is % retro)iru retro)irus s tr%smitted &y direct cot%ct with i"ected &lood %d &ody *uids$ *uids$ Si!i+c%t co cocetr%tios cetr%tios o" the )irus %r %re e ,reset i &lood- seme- )%!i%l %d cer)ic%l secretios %d cere&ros,i%l cere&r os,i%l *uid .CS/0 .CS/0 o" i"ected idi)idu idi)idu%ls$ %ls$ It is %lso "oud i &re%st mil1 %d s%li)%$ Se(u%l co cot%ct t%ct is the ,rim%ry mode o" tr%smis tr%smissio$ sio$ HI# is %lso tr%smitted throu!h cot%ct with i"ecte i"ected d &lood )i% eedle sh%ri! duri! i2ectio i2ectio dru! use or &y tr%s"usio$ tr%s"usio$ A,,ro(im%tely A,,ro(im%tely 345 to 675 o" i"%ts &or to HI#8,ositi)e mothers %re i"ected ,eri%t%lly$

Enzyme-linked immunosorbent ssy !ELISA" # is the most widely used screei! test it "orte HI# i"ectio$ i"ectio$ tests sts "or HI# %ti&odies$ $estern blot ntibody testin% # the cliet's serum is mi(ed with HI#

isk .'tors, older %dult- de&ilit%ted- se)erely immuode+cie immuode+ciet t ,eo,le- i2ectio dru! users- ,ersos with Hemo,hili%- reci,iets o" &lood tr%s"usios- immi!r%ts "rom H%iti %d homose(u%ls$ HI# eters ito the &ody 9  The )irus i"ects i"ects cells whi which ch h%)e the C CD: D: %ti!e 9 Oce iside the cell- the )irus sheds its ,rotei co%t 9 ;ses % e