Pa Tho Physiology of Colon Cancer

Pathophysiology of Colon Cancer Predisposing factors: • Age (56% >70yrs old) • Colorectal polyps • Family history • Previous colorectal cancer • Ulcerative colitis /colonic crohn’s disease

Diagnostic test: • Fecal occult blood test

Precipitating factors: Patient broke her right leg due to falling on the stairs Precipitating factors: • Diet – hit fat/low fibre • Smoking • Alcohol drinking • Lack of exercise

Etiology: Unknown

Abnormal proliferation of cells in the colon area Signs and Symptoms: • Rectal bleeding • Bloody stools • Abdominal pain • Fatigue • Constipation • Diarrhea • Nausea and Vomiting

Arising from epithelial lining of the intestine

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SigmoIdoscopy • Digital Rectum Exam

If treated

Benign polyps occur

If not treated

Surgical Treatment: • Colonoscopy • Virtual Colonoscopy

Continuous plorifetation of cells in the polyps

Increase in size ot the polyps

Exposure to carcinogens

Reduction likelihood of regrowth

Diagnostic test: Development of malignant tumor

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copy

Uncontrolled proliferation of cells in the tumor marrow Increase in size

COLON CANCER

If treated

Surgical Treatment: • Colonoscopy • Chemotherapy • Radiation

Reduction likelihood of regrowth

If not treated

Continues increase in size

Metatases of cancer cells in other organs

Proliferation of cancer cells in that area

Formation of new tumor

Complications occur

DEATH

SigmoIdos