Metabolismo de Los Nucleotidos
August 2, 2022 | Author: Anonymous | Category: N/A
Short Description
Download Metabolismo de Los Nucleotidos...
Description
7
K K G D K @ K R W H K C
IRDJBH^KNHT R I K V G J J B D Ç ^ B N S G
N B
C K H W R À @ K D G
D G S S B S G
N B
@ B N K D K I G
] .
^ B S D B S H T
C[F
E B T ^ K Ô I
3 = 7 1
G .
3
DH@]B^BIDKGT - Nb Nbtb tbr` r`ki kigr gr jg jgss dg dgrg rgdt dtbr bràs àstktkdg dgss `çs `çs k`ph k`phrt rtgi gitb tbss nb jhs jhs iu iudj djbô bôtktknh nhs. s. - Bschzgr jgs vàgs `btgcôjkdgs dgtgcôjkdgs y gigcôjkdgs nb jhs iudjbôtknhs pgrg knbitkfkdgr nbfbdths rbjg rbjgdk dkhi hign gnhs hs y jg jgss pgth pgthjh jheà eàgs gs rb rbjg jgdk dkhi hign gnhs hs dh dhii jhs jhs `k `ks` s`hs hs.. K K G D K @ K R W H K C
- Bstg Bstgcj cjbd bdbr br pg pgth thjh jheà eàgs gs k` k`ph phrt rtgi gitb tbss rbjgd bjgdkh khig igng ngss g gjtb gjtbrg rgdk dkhi hibs bs nbj nbj `btg `btgch chjkjks` s`hh nb jh jhss iudj iudjbô bôtktknh nhss
C[F
4
CGTBT
K K G D K @ K R W H K C
C[F
>
IRDJBHTKNHT [ IRDJBÔ^KNHT
K K G D K @ K R W H K C
C[F
2
K K G D K @ K R W H K C
C[F
6
IRDJBÔ^KNHT @HNKFKDGNHT •
•
K K G D K @ K R W H K C
•
Jgs `hnkfkdgdkhibs sb ngi prkidkpgj`bitb duginh fhr hr`g `gii pg pgrt rtbb nb jg jgss dgnb dgnbig igss nb ph phjkjkiu iudj djbô bôtktknh nhss Jgs `hnk hnkfkdgdkhibs `çs k`phrt rtgi gittbs shi `bt btkkjgdkôi b aknrhxkjgdkôi Bj hcob hcobtktkvvh nb jg jgss `hnk `hnkfkfkdg dgdk dkhi hibs bs
C[F
•
Sbdhihdk`kbith
•
Nbtb Nb tbr` r`ki kigg jg vkng vkng `bnk `bnkgg nb nbjh jhss SIG` SIG`
5
DGSGD^BSÀT^KDG DGSGD^BSÀT ^KDGT T K@]HS^ K@]HS^GI^B GI^BT T •
Jhs iudjbôtknhs phrtgi dgreg ibegtkvg g pA fkskhjôekdh
•
K K G D K @ K R W H K C
Thi nb pbr`ktb gcshrcbrnbtbr`kigr juz RV g 36= dgpgdbs i`, jh qub sus dhidbitrgdkhibs phr bspbdtrhfhth`btràg.
C[F
1
FRIDKHIBT NB JHT IRDJBÔ^KNHT TK@]JBT ]rbsbitgi trgisfbrbidkg brbidkg nb eruph. ]rbsbitgi ui gjth phtbidkgj nb trgisf ◦ G^] ↓
K K G D K @ K R W H K C
C[F
prkidkpgj trgisnudthr ckhjôekdh nb bibreàg jkcrb
◦ G@]d↓ fuidkhig dh`h sbeuinh `bisgobrh ◦ Gnbihskig 4¾”fhsfgth”2 4¾”fhsfgth”2¾¾”fhsfhsujfgth? nhignh nhignhrr nb sujf sujfgth gthss pgrg prhtbhejud prhtbhejudgihs. gihs. ◦ T” T”gnbihskj`btkhikig gnbihskj`btkhikig ↓nhignh nhignhrr nb eruphs `btk `btkjh jh
;
K K G D K @ K R W H K C
C[F
•
E^] ↓
•
E@]d ↓
•
RN]”gzudgr RN]” gzudgr ↓
•
prhtbàig y ejudhprhtbkigs.
•
D^] ↓
Fubitb bibreëtkdg sàitbsks nb prhtbàigs Tbeuinh `bisgobrh bi jg rbspubst rbspubstg g nb rbjgogdkôi nb `ÿsdujh ckhsàitbsks nb gzÿdgr gzÿdgr,, hjkehsgdgrknhs nb
Ckhsàitbsks nb fhsfhejkdbr fhsfhejkdbrhjbs, hjbs, bsfkiehs`kbjkig, bsfkiehs`kbjkig,
7=
]HJKIRDJBÔ^KNHT •
Jhs bijgdbs bitrb iudjbôtknhs ↓
•
Tb uibi jgs frgddkhibs pbithsgs pbithsgs nkrbddkôi 4‛↓2‛
•
NIG pubnb `gitbibr `gitbibrsb sb nurgitb jgrehs pbrkhnhs nb tkb`ph nbcknh g jg fgjtg nb aknrôjksks.
•
SIG bs `bihs bstgcjb
•
K K G D K @ K R W H K C
FHTFHNKBT^BS
•
•
Jgs dgnbigs skb`prb tkbib ui bxtrb`h 4‛ y bxtrb`h 2‛ Ihr`gj`bitb bj bxtrb`h 2msb bidubitrg fhsfhrkjgnh.
C[F
77
K K G D K @ K R W H K C
C[F
73
K K G D K @ K R W H K C
@B^GCHJKT@H IRDJBH^KNHT NB
C[F
74
DHITKNBS GDKHI DKHIBT BT K@]HS^ K@]HS^GI^BT GI^BT DHITKNBSG •
•
•
K K G D K @ K R W H K C
Jg sàitbsks nb purkigs y pkrk`knkigs bs uig sàitbsks Nk ihvh g pgrtkr nb kitbr`bn kitb r`bnkgrh kgrhss gifkcôjkdhs gifkcôjkdhs.. Bj aàegnh bs bj prkidkpgj ôregih prhnudt dthhr nb iu iuddjbôtknhs Jhs G. G.I I. y iudjb djbôtknhs kiebrknhs sb nbergngi bi bj kitbst stkkih. GI --¼ `hihu hihuddjbôtknhs --¼ ]urkigs y pkrk` k`kn knkkigs ---¼ Gd. ßrkdh Dh`pubsth sths kiybdtg dtgnhs sk pubnbi sbr kidhr idhrpphrgnhs bi bj NIG
C[F
•
•
7>
CKHTÀI^BTKT NB IRDJBÔ^KNHT NB ]RSKIG[ ]KSK@KNKIG •
K K G D K @ K R W H K C
C[F
•
•
Bxkstbi
`bdgiks`hs
kitrgdbjujgrbs
qub
rbeujgi
jgs
dhc hiobtk dtkv bvihtrnb gdkhjhiergr bsgr ah`bhstgsks. iudjbôtknh trkfhsfgths (I^]), thnh dhi bj hcob er ah`bhstgsks. Jg sàitbsks gu`bitg nurgitb bj drbdk`kbith, h jg rbebibrgdkôi nb tbok tboknh nh,, nk nkvk vksk skôi ôi db dbju jujg jgrr. Jg sà sàit itbs bsks ks ki vkvh sb ng bi dhidbitrgdkhibs dhierubitbs dhi jg ibdbsk ibd bskng ngnn fks fkskhj khjôe ôekdg kdg..
72
CKHTÀI^BTKT NB IRDJBÔ^KNHT NB ]RSKIG •
K K G D K @ K R W H K C
C[F
^rbs prhdbshs k`phrtgitbs pgrg jg ckhsàitbsks? 7. Tài Tàitbs tbsksks nb kit kitbr` br`bnk bnkgrk grkhs hs gif gifkcô kcôjkd jkdhs hs 3. Tài àittbsks bsks nb G@ G@]] y E@ E@]] 4. Sb Sbsdg sdgtb tb nnbb pu purki rkigg y iiudj udjbôs bôsknh knhss nb purki purkigg
76
TÀI^BTKT NBJ ]SHNRD^H KI^BS@BNKH NB @HIHFHTFG^H NB KIHTKIG K@] •
Tustrgth kikdkgj nb Skchsg 2 fhsfgth
•
•
K K G D K @ K R W H K C
C[F
]rk`br fhsfhrrkchskj pkrhfhsfgth hsfgth ]S]] S hrrkchskj skitgsg 2 pkrhf Bizk`g prhnudth bidgregngkitbr`bnkh? nb jg sàitbsks2 fhsf Kitbr`bnkgrkh bi jg rbdupbrgdkôi nb purkigs Ckhsàitbsks nb iudjbôtknhs nb pkrk`knkigs Tàitbsks nb IGN y IGN]
•
•
•
75
K K G D K @ K R W H K C
C[F
71
TÀI^BTKT NB G@][ E@] G ]GS GS^KS ^KS NB K@]
K K G D K @ K R W H K C
C[F
G pgrtkr nbj n bj K@] phr rg`gs sbpgrgngs sb fhr`g? G@] [ E@] ^rgisfbrbidkg nb G^] — ¼ E^] 3ng Fhsfhrkjgdkôi Fhsfhrkjgdk ôi fhsfhrkjh G^]? EN] Fhsfhrkjgdkôi hxkngtkvg? GN] — ¼ EN]
7;
SBWRBSK@KBI^HT •
•
K K G D K @ K R W H K C
C[F
•
•
•
•
Nbrkvgnhs Nbrkv gnhs ^btrga ^btrgakfhj kfhjgth gth ? Gd fôjkdh > G^] Ejutg`kig Gspgrtgth Dgrchih bi fhr`g nb DH3 E^]
3=
•
•
K K G D K @ K R W H K C
C[F
Jg vàg nb sàitbsks bstg fhr`gng phr bizk`gs `ujtkfuidkhigjbs qubb dgtg qu dgtgjkjkzg zgii vgrk vgrkgs gs rbgdd bgddkh khib ibss bizk bizk`ç `çtktkdg dgss Jg nbfkdkbidkg nb Gd fôjkdh bst stgg rbjgdkhigng dhi uig nbfkdkbidkg bi jg sàitbsks nb purkigs.
37
SBTDG G^B SBGDDKHIBT NB SBTD •
Dhivbrskôi nb? •
•
•
•
K K G D K @ K R W H K C
C[F
•
]urkigs Skchiudjbhsknhs Nbshxkrkchiudjbhsknhs
@HIHIRDJBH^KNHT
Tb rbqukbrb `bihs bibreàg qub jg sàitbsks nb ihvh. Tb rbdhihdbi 3 `bdgiks`hs? 7. Sb Sbsd sdgt gtbb nb cg cgsb sbss ikt iktrrhebi hebign gngs gs 3. Sbs bsdg dgttb nb nb iiud udjb jbôs ôskn knhs hs
33
7. SBTDG^B NB CGTBT? GNBIKIG [ AK]H AK]HQGI^KIG QGI^KIG •
•
K K G D K @ K R W H K C
C[F
Gnbikig fhsfhrrkchjskj trgisfbrgsg trgisfbrgsg
Gnbikig --¼ G@] Akphxgitkig-Eugi Akphxgitkig-Eugikig kig fhsfhrrkchjskj trgisfbrg trgisfbrgsg sg Akphxgikig Akphxg ikig --¼ K@] Eugikig — ¼ E@]
34
3. SBTDG SBTDG^B ^B NB SKCHIRDJ SKCHIRDJBHTKNHT BHTKNHT NB ]RSKIG? ]RSKIG?
•
K K G D K @ K R W H K C
•
Gnbihskidkigsg?? Gnbihskidkigsg
Gnbihskig — ¼ G@] y nG@] Nbshxkdktknkigsg?
C[F
nDktknkig y nEugihskig — ¼ nD@] y nE@]
3>
]SKIDK]GJBT ]SHNRD^HSBT HSBT ]SKIDK]GJBT ^BOKNHT ]SHNRD^ +)) + Aàegnh K K G D K @ K R W H K C
C[F
-) Dbrbcrh (]S]]) Brktrhdkths (2fhsfhrrkchskjg`kig) Jfhsfhrrkchskjg`kig) bud udhd hdkkths (2-
32
SBERJGDKHI DKHI NB JG TÀI^BTKT NB SBERJG ]RSKIGT Bj rbeujgnhr prkidkpgj? nksphikckjkngn nb ]S]] K K G D K @ K R W H K C
C[F
Jg sàitbsks nb ]S]] nbpbinb? •
Nksphikckjkngn nb rkchsg2-
•
fhsfgth Gdtkvkngn nb jg ]S]] skitgsg.
]S]] skitgsg — ¼ G@],
GN], E@] y EN]. •
Sbeujgdkôi phr rbtrhgjk`bitgdkôi?
36
TÀI^BTKT NB NKFHTFG^HT NB NBTHQKSKCHIRD NBTH QKSKCHIRDJBHTKNHT JBHTKNHT nI^] nI^] •
•
•
•
•
K K G D K @ K R W H K C
DH@]JBOH SKCHIRJDBH^KNH SBNRD^GTG Jg gdtkv dtkvggdk dkôi ôi nb dh`pj h`pjbo bohh bizk bizk`ç `çtktkddh sb gdtkv dtkvgg bi jg sài sàitbsks bsks gd gdttkv kvgg nb NIG NIG Tb rbgjk bgjkzg zg phr phr rbnud bnuddk dkôi ôi nb nkf nkfhs hsfg fgth thss nb rkch rkchiu iudj djbh bhsk sknh nh ]r ]rhdb hdbsh sh gjtg`bi gjtg`bitb tb rbeuj rbeujgnh gnh Sbqubrk`kbiths? - ^khrrbnhx khrrbnhxkig kig
C[F
khr rbnh rbnudtgsg gsg.. --I^khrrb GN GN] ]nhxki A xkigg rbnudt
35
CKHTÀI^BTKT NB IRDJBÔ^KNHT NB ]KSK@KNKIG •
•
K K G D K @ K R W H K C
•
Jhs sucstrgths kikdkgjbs? DH3, Ejutg`kig , G^]. Jg bizk`g prk`grkg? Dgrcg`hkj fhsfgth skitgsg KK (dkthsôjkdg)
Sbqubrk`kbiths? •
•
•
•
•
C[F
Gspgrtgth Ejutg`kig IGNA ^btrgaknrhfhjgth ]S]]
31
K K G D K @ K R W H K C
C[F
3;
@BNKDG@BI^HT KIAKCKNHSBT NB JG TÀI^BTKT ]KSK@KNKIG •
•
•
Sx 73 rbqukbrb nb tbtrgaknrhfhjgth sb rbnudb g nkaknrhfhjgth. Tb rbqukbrb nb jg Nkaknrhfhjgthrbnudtgsg pgrg jg dhivbrskôi g tbtrgaknrhfhjgth. tbtrgaknrhfhjgth. Bj `bthtrbxgth bs dgpgz nb kiakckr g jg bizk`g
K K G D K @ K R W H K C
C[F
4=
SBERJGDKHI DKHI NB JG TÀI^BTKT NB SBERJG IRDJBÔ^KNHT NB ]KSK@KNKIG •
•
•
K K G D K @ K R W H K C
•
Sbeujgdkôi gjhstërkdg Sbeujgdkôi nb jg bxprbskôi eëikdg Jg sàitbsks nb iudjbôtknhs nb purkig y pkrk`knkig sb rbeujg nb `gibrg dhhrnkigng Iudjbôtknhs nb purkig y pkrk`knkig kiakcbi jg bizk`g ]S]] skitgsg
C[F
47
R^] (-)
Dgrcg`hkj fhsfgth skitgsg KK K K G D K @ K R W H K C
iudjbôtknhs purkig (-)
(Sx7)
]S]] (+)
G^] (+) Gspgrtgth trgisdgrcg`hkjg sg (Sx 3)
D^]
C[F
(-)
43
K K G D K @ K R W H K C
C[F
44
K K G D K @ K R W H K C
DG^GCHJKT@H ]SH^BKDH
C[F
4>
DG^GCHJKT@H NB JGT ]RSKIGT •
•
K K G D K @ K R W H K C
C[F
Gnbihskig y Eugihskig — ¼ Gd. ßrkdh Jhs sbrbs au`gihs dgrbdb`hs nb jg Rrkdgsg Gd. ßrkdh Gjgithkig •
42
^SGIT^HSIHT NBJ DG^GCHJKT@H NB JGT ]RSKIGT ]G^HJHEÀG EH^G
K K G D K @ K R W H K C
C[F
Tàinrh`b nb Jbsda-Iyagi
NBFBD^H ]S]] skitgsg
HCTBSVGDKHIBT Bjbvgng gfkikngn g jg Skchsg 2 fhsfgth Sbskstbidkg g jg kiakckdkôi Gihr`gjkngnbs bi jg bxdrbdkôi rbigj Dhidbitrgdkhibs Dhidbit rgdkhibs bjbvgngs drkstgjkzgdkôi drkstgjkzgdkôi nb jhs urgths bi tboknh cjginh y grtkdujgdkhibs. Grtrktks ehthsg akphxgitkigeugikig ]rhnuddkôi bxdbskvg fhsfhrrkchskjtrgisfbrgs Bpkshnkhs frbdubitbs nb jktkgsks phr gdknh ÿrkdh g, Tàinrh`b nb guth`utkjgdkôi Kidrb`bith nbj ]S]] kitrgdbjujgr Kidrb`bith ]rhnuddkôi bxdbskvg nb purkig. @utgdkôi phr nbjbdkhi, dg`ckh nb `grdh `grdh,, sustktudkhibs nb cgsbs y b`pgj`b gcbrrgitb nb `SIG.
46
^SGIT^ IT^HSIH HSIHT T NBJ DG DG^ ^GCH GCHJKT@ JKT@H H ^SG NB JGT ]RSKIGT
K K G D K @ K R W H K C
C[F
]G^HJHEÀG
NBFBD^H
HCTBSVGDKHIBT
Bifbr`bngn nb
Nbfkdkbidkg nb
]rhnuddkôi bxdbskvg nb purkig b akpbrurkdb`kg
vhi Ekbrlb
ejudhsg-6-fhsfgtgsg) Ebibrgdkôi gu`bitgng nbj prbdurshr nb ]S]] gu`bitgng rkchsg 2-fhsfgth. ]hr gdknhsks jçdtkdg sb kidrb`bitg bj u`crgj rbigj pgrg urgth.
Akphurkdb`kg
Nbfkdkbidkg nb xgitkig hxkngsg Akphurkdb`kg y jg bxdrbdkôi kidrb`bitgng kidrb`bitgng nb akphxgitkig akphxgitki g y xgitkig
Nbfbdth ebiëtkdh h g ng÷h abpçtkdh ergvb. Nbfkdkbidkg bizk`çtkdg ergvb pubnbi tbibr xgitkiurkg h jktkgsks phr xgitkig.
45
DG^GCHJKT@H NB JGT ]KSK@KNKIGT •
Jhs prhnudths fkigjbs shi aknrhshjucjbs. Γ
@btkj `gjhigth
g`kihkshcutkrgth
Tuddkikj-DhG
sb`kgjnbaknh K K G D K @ K R W H K C
•
•
@gyhr bxdbdkhig nb γ-g`kihkshcutkrgth bi jbudb`kg y bi jg bxphskdkôi ergvb g rgyhs Q. Gskçtkdhs bxdrbtgi nb `hnh skstb`çtkdh γ-g`kihkshcutkrgth.
C[F
41
K K G D K @ K R W H K C
C[F
4;
GJ^BSGDKHIBT BI BJ DG^GCHJKT@H JGT ]KSK@KNKIGT ]G^HJHEKG GJ^NB BSGDKH I HCTBSVGDKHIBT
K K G D K @ K R W H K C
Gdknurkgs hrôtkdg gdh`pg÷g gj
Kidgpgdkngn `kthdhinrkgj pgrg usgr
Bxdrbdkôi kidrb`bitgng nb
sàinrh`b nb Sbyb Gdknurkg hrôtkdg tkph K
dgrcg`hkj fhsfgth Nbfkdkbidkg Hrhtgth fhsfhrrkchskjtrgisfbrgsg Hrhtknkjgthh nbsdgrchxkjgsg Hrhtknkjgt Nbfkdkbidkg shjh nb hrhtknkjgth nbsdgrchxkjgsg
gdknh hrôtkdh, urgdkjh y urknkig
Gdknurkg hrôtkdg tkph KK
Gjhpurkihj, 6 gzgurknkig dh`pktb dhi bj gdknh hrôtkdh, hrôtkdh, kidrb`bitg kidrb`bitg jg bxdrbdkôi nb gdknh hrhtkdh hrhtkdh y hrhtknkig.
C[F
>=
K K G D K @ K R W H K C
ESGDKGT…
C[F
View more...
Comments
