Laporan Ir

LAPORAN PRAKTIKUM ANALISIS SEDIAAN FARMASI ANALISIS SENYAWA KAFEIN DENGAN METODE SPEKTROFOTOMETRI FTIR 

Oleh : Golongan Q / Kelompo D !"

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FAKULTAS FAKULTAS FARMASI UNI+ERSITAS KATOLIK WIDYA MANDALA SURA6AYA &)!-

I. Tujuan Praktikum •

Un30 mempela,a*# 7aga#mana 8a*a meng#$en3#9#a2# 7ahan 7a0 o7a3 / 2en5a%a ha2#l 2#n3e2#2 $engan mengg0naan 2pe3*o9o3ome3e* FTIR 

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Un30 mela0an #n3e*p*e3a2# $a3a 2pe3*0m IR $a*# a3 5ang $#anal#2a"

II. Dasar Teori

Spe3*o2op# #n9*ame*ah me*0paan 2alah 2a30 ala3 5ang 7an5a $#paa# 0n30  meng#$en3#9#a2# 2en5a%a; 7a# alam# ma0p0n 70a3an" Dalam 7#$ang 9#2#a 7ahan; 2epe*3# 7ahanFo0*#e* T*a29o*m In9*a Re$@ a$alah 2ama $engan Spe3*o9o3ome3e* IR $#2pe*2#; 5ang mem7e$aann5a a$alah pengem7angan pa$a 2#23#m op3#n5a 2e7el0m 7e*a2 2#na* #n9*a me*ah mele%a3# 8on3oh" Da2a* pem##*an $a*# Spe3*o9o3ome3e* FTIR a$alah $a*# pe*2amaan gelom7ang 5ang $#*0m02an oleh ean 6ap3#23e o2eph Fo0*#e* >!1.2#$# ,a*#@ 0n30 2en5a%a 3e*2e703" Da*# $e*e3 Fo0*#e* 3e*2e703 #n3en2#3a2 gelom7ang $apa3 $#gam7a*an 2e7aga# $ae*ah %a30 a3a0 $ae*ah 9*e0en2#" Pe*07ahan gam7a*an #n3en2#3a2 gelom7ang *a$#a2# ele3*omagne3# $a*# $ae*ah %a30 e $ae*ah 9*e0en2# a3a0 2e7al#n5a $#2e703 T*an29o*ma2# Fo0*#e* >Fo0*#e* T*an29o*m@" Selan,03n5a pa$a 2#23#m op3# pe*ala3an #n23*0men FTIR $#paa# $a2a* $ae*ah %a30 5ang non $#2pe*2#9" Se7aga# 8on3oh apl#a2#  pemaa#an gelom7ang *a$#a2# ele3*omagne3# 5ang 7e*$a2a*an $ae*ah %a30 a$alah #n3e*9e*ome3e* 5ang $#em0aan oleh Al7e*3 A7*aham M#8hel2on >4a*,a$#; !??(@" Se8a*a e2el0*0han; anal#2#2 mengg0naan Spe3*o9o3ome3e* FTIR mem#l## $0a ele7#han 03ama $#7an$#ngan me3o$a on=en2#onal la#nn5a; 5a#30 :

!" Dapa3 $#g0naan pa$a 2em0a 9*e%en2# $a*# 20m7e* 8aha5a 2e8a*a 2#m0l3an 2eh#ngga anal#2#2 $apa3 $#la0an le7#h 8epa3 $a*#pa$a mengg0naan 8a*a 2e0en2#al a3a0 28ann#ng" &" Sen2#3#9#3a2 $a*# me3o$a Spe3*o9o3ome3*# FTIR le7#h 7e2a* $a*#pa$a 8a*a $#2pe*2#; 2e7a7 *a$#a2# 5ang ma20 e 2#23#m $e3e3o* le7#h 7an5a a*ena 3anpa ha*02 melal0# 8elah >2l#3le22@" S#23em op3# Spe3*o9o3ome3e* FTIR $#lengap# $engan 8e*m#n 5ang 7e*ge*a 3ega  l0*02 $an 8e*m#n 5ang $#am" Dengan $em##an *a$#a2# #n9*a me*ah aan men#m70lan  pe*7e$aan ,a*a 5ang $#3emp0h men0,0 8e*m#n 5ang 7e*ge*a >M@ $an ,a*a 8e*m#n 5ang $#am >F@" Pe*7e$aan ,a*a 3emp0h *a$#a2# 3e*2e703 a$alah & 5ang 2elan,03n5a $#2e703 2e7aga# *e3a*$a2# >@" 4070ngan an3a*a #n3en2#3a2 *a$#a2# IR 5ang $#3e*#ma $e3e3o*  3e*ha$ap *e3a*$a2# $#2e703 2e7aga# #n3e*9e*og*am" Se$angan 2#23#m op3# $a*# Spe3*o9o3ome3e* IR 5ang $#$a2a*an a3a2 7ee*,an5a #n3e*9e*ome3e* $#2e703 2e7aga# 2#23em op3# Fo0*#e* T*an29o*m In9*a Re$" S#23em op3# FTIR $#g0naan *a$#a2# LASER >L#gh3 Ampl#9#8a3#on 75 S3#m0la3e$ Emm#22#on o9 Ra$#a3#on@ 5ang 7e*90ng2# 2e7aga# *a$#a2# 5ang $##n3e*9e*en2#an $engan *a$#a2# #n9*a me*ah aga* 2#n5al *a$#a2# #n9*a me*ah 5ang $#3e*#ma oleh $e3e3o* 2e8a*a 030h $an le7#h 7a#" De3e3o* 5ang $#g0naan $alam Spe3*o9o3ome3e* FTIR a$alah TGS >Te3*a Gl58e*#ne S0lpha3e@ a3a0 MT >Me*80*5 a$m#0m Tell0*#$e@" De3e3o* MT le7#h 7an5a 

$#g0naan a*ena mem#l## 7e7e*apa ele7#han $#7an$#ngan $e3e3o* TGS; 5a#30 mem7e*#an *e2pon 5ang le7#h 7a# pa$a 9*e%en2# mo$0la2# 3#ngg#; le7#h 2en2#3#9; le7#h 8epa3; 3#$a $#penga*0h# oleh 3empe*a30*; 2anga3 2ele3#9 3e*ha$ap ene*g# =#7*a2# 5ang $#3e*#ma $a*# *a$#a2# #n9*a me*ah >R023#na; &)).@"

III.

Karakteristik Coffeinum / Kofein

>FI I+; hal" &-'@

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Peme*#an: Se*70 p03#h a3a0 7en30 ,a*0m meng#la3 p03#h 7#a2an5a meng< g0mpal 3#$a 7e*7a0 *a2a pah#3" La*03an 7e*2#9a3 ne3*al 3e*ha$ap e*3a2 lam02" 6en30  h#$*a3n5a mea* $# 0$a*a"

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Kela*03an: Aga 20a* la*03 $alam a#*; $alam e3anol m0$ah la*03 $alam lo*o9o*m 20a* la*03 $alam e3e*"

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I$en3#9#a2#: Spe3*0m 2e*apan #n9*ame*ah a3 5ang 3elah $#e*#ngan $an $#$#2pe*2#an $alam m#n5a m#ne*al men0n,0an ma2#m0m han5a pa$a pan,ang gelom7ang 5ang 2ama 2epe*3# pa$a o9e#n 6PFI"

IV.

Cara Kerja •

Mengh#$0pan In23*0men  N5alaan Komp03e*

 Tean 3om7ol ON pa$a #23*0men

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 pa$a So93%a*e Spe83*0m" •

M0la# S8an !" Kl# #on Background

 I2# nama Ko9e#n S3an$a*J

 Le3aan Ko9e#n m0*n#

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$#a3a2 pla3 UATR  Kl# #on Scan  M0n80l 2pe83*0m Ko9e#n S3an$a*J" &" Kl# #on  Background   I2# nama Ko9e#n SampelJ Le3aan 2ampel 

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Ko9e#n ha2#l #2ola2# pla3 UATR •

V. Hasil

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 Kl# #on Scan

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 M0n80l 2pe83*0m Ko9e#n

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SampelJ" P*#n3 2pe83*0m Ko9e#n S3an$a*$ $an Ko9e#n Sampel"

Ia3an Ko9e#n 4a2#l I2ola2# CO 23* !.?(;& 8mFT< IR@J; Seolah T#ngg# Ene*g# $an M#ne*al; ep0  a%a Tengah" 4a*,a$#; W" !??(" Ilm0 K#m#a Da2a* Anal#3#" E*langga" aa*3a" R#23#na; M" &))." Pe30n,0 P*a3#0m In23*0men K#m#a" STTN  6a3an" Yog5aa*3a"