La Contribucion Al Senati 2017777777777777

 

Siovcrsofef Eifoie Eifoie Ic Ic stlr Me Me mcrcs Zcde Zcde zqucz

Mlitciofl DE MLIVROBSMOÝI ED ]CIEVO .......... ...................... ............................. ............................. ............................. ......................... ........ = 5. MLIMC[ MLIMC[VL VL FC MLIVROBSMOÝ MLIVROBSMOÝI I ...... .......... ......... ......... ........ ........ .......... .......... ......... ......... ......... ......... ........ .......... ........ = 2. =. 6. 3. :. >. 0. ?. 5;.

]SACVL] EJCMVL] ED [ENL [ENL FC DE ML MLIVROBS IVROBSMOÝI MOÝI .... ........ ......... ......... ........ ........ ........ ...... = Cgprcses Cxmcptuef Cxmcptuefes es .... ........ ......... ......... ........ ........ ........ .......... .......... ......... ......... ........ ........ ........ .......... .......... ........ ........ ........ ...... 6 Rcguicrem Rcguicremolics olics Ejcmte Ejcmtefes fes .... ........ ......... ......... ........ ........ ........ .......... .......... ......... ......... ........ ........ ........ .......... .......... ........ ....... ... 3 Rcguicrem Rcguicremolics olics cxmduo cxmduofes fes .... ......... ......... ......... ......... ........ ........ .......... .......... ......... ......... ......... ......... ........ ......... ......... ......... ....... .. 3 Oismropm Oismropmoýi oýi .... ........ ......... ......... ......... ......... ........ .......... .......... ........ ........ ......... ......... ........ .......... .......... ........ ......... ......... ......... ......... .......... .......... ...... : BE]C OG[L OG[LIOBDC IOBDC F FC C DE MLIVROBSMOÝI MLIVROBSMOÝI ..... .......... ......... ........ ........ ........ .......... .......... ......... ......... ........ ...... .. : VE]E FC DE MLIVRO MLIVROBSMOÝI BSMOÝI ....... ........... ......... ......... ........ ........ .......... .......... ........ ......... ......... ........ ........ .......... .......... ....... ... : [DEQL FC [ENL .... ......... ......... ......... ......... ........ ........ ........ ......... ......... ........ ........ ........ ......... ........... .......... ........ ......... ......... ........ ........ ...... > FCMDER FCMDEREMOÝ EMOÝI I EISE EISED D ED ]C ]CIEVO IEVO ........ ............. ......... ......... ......... ........ ......... ......... ......... ......... ......... ......... ....... ... >

55. [EN [ENL L FC DE MLIVR MLIVROBS OBSMOÝ MOÝI I [LR GCF GCFOL] OL] CDCMV CDCMVRÝI RÝIOML OML] ] ... ...... ..... ..... ...... ..... 0 52. BE]C DCNED ....... ........... ........ ........ ......... ......... ........ ........ ........ ......... ......... ........ ........ ........ .......... .......... ......... ......... ......... ......... ........ ....... ... 0 5=. ME]L[R ME]L[RÅMVOML ÅMVOML ....... ........... ........ ........ ........ ........ .......... .......... ........ ........ ......... ......... ........ ........ ........ ......... ......... ........ ........ ........ ...... 5; 56. MLIMDS MLIMDS]OLIC ]OLIC] ] .... ........ ........ ........ ........ ........ ........ .......... .......... ........ ........ ........ ........ ........ ........ ........ ........ ......... ......... ......... ......... .... 5= MLIVROBSMOLIC] ED ]CIMOML ............ ........................ ............................ .............................. .............................. .................. 56 5.- oitrlfummoýi........... oitrlfummoýi ........................ .............................. ............................. ............................ .............................. .............................. ................... ... 56 2.- GERML ILRGEVOZL .......... ........................ .............................. ............................ .......................... .......................... ................... ....... 53 =.-EGBOVL FC DE E[DOMEMOÝI .................................... ................................................ ......................... ......................... ............ 53 6.-]SACVL] FC DE LBDONEMOLI ........................ ........................................ .............................. .............................. ................ 5: 6.5 ]SACVL EMVOZL .......... ...................... ............................ ............................. ......................... .......................... ......................... ........... 5: 6.2. ]SACVL [E]OZL ........................ ........................................ ............................ .......................... .......................... ..................... ......... 5: 3.-FCVCRGOIEMOLI FC DE BE]C OG[LIOBDC ........... ....................... ............................. .......................... ......... 5> :.-VE]E FC MLIVROBSMOÝI ED ]CIMOML............ ]CIMOML........................ ......................... ......................... ................... ....... 5> >.- IEMOGOCIVL FCDE LBDONEMOÝI VROBSVEROE ........... ....................... ............................ .................. 5> 0.- JLRGE _ DSNER FC [ENL ..................................... ................................................. ......................... ......................... ............ 50 ?.- ]EIMOLIC] E[DOMEBDC] CI ME]L FC OIMSG[DOGOCIVL CI CD [ENL ........................ .......... .............................. ............................ .......................... .......................... ......................... ............................... ............................... ................. .... 50 5;.- LBDONEMOÝI FC [RC]CIVER DE FCMDEREMOÝI FCMDEREMOÝI ASREFE F FC C LBRE] 5? 55.-FCFSMOBODOFEF FCD [ENL FCD ]CIMOML MLIVRE CD OG[SC]VL EDE RCIVE ........... ....................... ............................ ............................. .............................. ............................. ............................. .............................. ................ ... 5? VROBSVEMOLI OO

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Siovcrsofef Eifoie Eifoie Ic Ic stlr Me Me mcrcs Zcde Zcde zqucz 52.-FCZLDSMOLI FC [ENL] OIFCBOFL] OIFCBOFL] CI CPMC]L FCDE MLIVROBSMOÝI ED ]CIMOML....................... ]CIMOML........... ............................ .............................. .............................. ............................ ............................. ........................ ....... 5? 5=.-MEG[L FC E[DOMEMOÝI ........... ....................... ............................ .............................. .............................. ......................... ......... 5? 56.-MRLILNREGE FC LBDONEMOLIC] - CACRMOMOL 2;5: Cs epdomebdc e1 .... 2; 53.-CPONOBODOFEF FC [ENL FC DE MLIVROBSMOÝI ED ]CIMOML .......... ................. ....... 25 5:.-DSNERC] FC [ENL.......... [ENL ...................... ............................. ............................. ........................ .......................... ....................... ......... 25 5>.-MÝFONL VROBSVEROL .......... ...................... .............................. .............................. ........................ .......................... ................... ..... 25 50.-FCMDEREMOÝI ASREFE ...................... ...................................... ............................. .............................. ............................ ........... 22 5?.- ME]L [REMVOMLFC FCVCRGOIEMOLI ED ]CIMOML ............................ ............................... ... 26

VROBSVEMOLI OO

[e noie 2

 

Siovcrsofef Eifoie Eifoie Ic Ic stlr Me Me mcrcs Zcde Zcde zqucz

DE MLIVROBSMOÝI ED ]CIEVO De Mlitrobumoýi ed ]CIEVO cs uie eplrtemoýi mrcefe plr de Dcy Il. 2:2>2, quc ncicre ci jevlr fc des cgprcses oifustroedcs eplrteitcs cd bcicjomol fcd fomtefl fc merrcres tïmiomes e su pcrslied pere ui gcalr fcscgpcõl fc sus juimolics y de jlrgemoýi fc prljcsoliedcs mlgpctcitcs mlgpctcitcs ci cd fcscgpcõl fc emtovo emtovofefcs fefcs prlfumtoves fc topl oifustroed.

5. MLIMC[VL FC MLIVROBSMOÝI Cs cd trobut trobutl l muye lbdonem lbdonemoýi oýi tocic mlgl `cm`l ncicreflr bcicjomo bcicjomols ls fcrovefls fc de rcedozemoýi fc lbres pñbdomes l fc emtovofefcs cstetedcs. Des eplrtemo eplrtemolics lics ed scnurl slmoed fc seduf- C]]EDS C]]EDSF F y e de ljomoie

fc

ilrgedozemoýi prlvosolied ” LI[ sc ronci plr des ilrges fc cstc mýfonl, sedvl ci equcddls espcmtls quc plr su ieturedcze rcquocrei ilrge cspcmoedcs, dls gosgls quc scråi scõedefls plr fcmrctl suprcgl.

2. ]SACVL] EJCMVL] ED [ENL FC DE MLIVROBSMOÝI MLIVROBSMOÝI Des pcrs pcrslies lies ietu ietured redcs cs l aur aurçfo çfomes mes quc fcse fcserrld rrlddci dci emtovo emtovofefc fefcss oif oifust ustroed roedcs cs mlgprcifofes ci de Metcnlrçe F fc de Mdesojomemoýi Oifustroed Oitcriemolied Siojlrgc (MOOS) fc tlfes des emtovofefcs cmliýgomes fc des Iemolics Siofes (Rcvosoýi (Rcvosoý i =), y equcddes quc fcserrlddci deblrcs fc oistedemoýi, rcperemoýi rcperemoýi y geitciogocitl. geitciogo citl. Cståi lbdonefes e mlitrobuor mli cd ]CIEVO peneifl uie mlitrobumoýi plrmcitued medmudefe slbrc cd tlted fc des rcguicremolics fc dls trebeaeflrcs, trebeaefl rcs, e joi fc prlplrmo prlplrmolier lier jlrgemoýi prljcsolied y mepemotemoýi mepemotemoýi e dls trebeaef treb eaeflrcs lrcs fc des emt emtovo ovofefc fefcss prlf prlfumto umtoves, ves, fc emuc emucrfl rfl mli cd sonu sonuocit ocitc c mrlilnrege y plrmciteacs1 VROBSVEMOLI OO

[e noie =

   

Siovcrsofef Eifoie Eifoie Ic Ic stlr Me Me mcrcs Zcde Zcde zqucz ]ýdl csteråi suactls ed penl equcddes cgprcses quc ci cd eõl eitcrolr `eyei tciofl ui prlgcfol supcrolr e vcoitc (2;) trebeaeflrcs.  Equcddes cgprcses quc il tcinei gås fc vcoitc (2;) trebeaeflrcs ci prlgcfol plfråi plfrå i eplr eplrter ter de Mlit Mlitrob robumo umoýi ýi fc jlrg jlrge e vlduite vlduiteroe, roe, eblieifl cd glit glitl l cquovedcitc ed 2% fc de Siofef Ogplsotove Vrobuteroe (SOV) voncitc. Fureitc cd eõl 5??6 5.3% Fureitc cd eõl 5??3 5.23% Fureitc cd eõl 5??: 5.;;%

E pertor fc 5??> 5??> ;.>3% Mueifl, efcgås fc de emtovofef oifustroed, uie cgprcse f fcserrlddc cserrlddc ltres emtovofefcs cmliýgomes, cd penl fc de motefe mlitrobumoýi sc `erå ñiomegcitc slbrc cd glitl fc des rcguicremolics mlrrcsplifocit mlrrcsplifocitcs cs ed pcrslied fcfomefl e de emto emtovofef vofef oifus oifustroed troed y e deb deblrcs lrcs fc oistede oistedemoýi, moýi, rcperemoýi rcperemoýi y geit geitciogoci ciogocitl. tl.  Esç tegboïi, des cgprcses c gprcses quc il fcserr fcserrlddei lddei emtovofefcs mlgprcifofes fcitrl fc de rcjcrofe metcnlrçe F peneråi de mlitrobumoýi slbrc des rcguicremolics fcd pcrslied fcfomefl e deblrcs fc oistedemoýi, rcperemoýi y geitciogocitl rcedozefes teitl e jevlr fc de prlpo prlp oe cgprcse mueitl fc tcrmcrls.

=. CG[RC]E] CPMC[VSEFE] De Dcy I» 2:2>2 cstebdcmc quc il sc cimucitrei lbdonefes e de mlitrobumoýi ed ]CIEVO des cgprcses quc sc cimucitrci ci ednuils fc cstls supucstls1  

Des cgprcses quc sc fcfoquci e de oistedemoýi, rcperemoýi y geitciogocitl fcitrl fc de emtovofef fc de mlistrummoýi, mlgprcifofes ci de metcnlrçe "J", Fovosoýi 63 fc de MOOS (Rcvosoýi =) y quc cståi ejcmtes e de mlitrobumoýi ed ]CIMOML il cståi lbdonefes ed penl fc de mlitrobumoýi ed ]CIEVO.

 

Des cgprcses quc fureitc cd eõl eitcrolr `ubocr `ubocrei ei tciofl ui prlgcfol fc vcoitc trebeaeflrcs l gcils fcfomefls e de emtovofef oifustroed y e deblrcs fc oistedemoýi, rcperemoýi y geitciogocitl.

VROBSVEMOLI OO

[e noie 6

   

Siovcrsofef Eifoie Eifoie Ic Ic stlr Me Me mcrcs Zcde Zcde zqucz

6. RCGSICREMOLIC] EJCMVEFE]  E cjcmtls fc rcedozer cd penl fc de mlitrobumoýi ed ]cieto sc mlisofcre rcguicremoýi tlfl penl quc pcrmobe cd trebeaeflr plr de prcstemoýi fc s cr vom ol ol s l,  sce mued jucrc su lronci, ieturedcze l p crsl c rslie iedc dcs, s, su suac actl tl e ml i tret  l fcilgoiemoýi, pere dl mued sc tcifrå ci mucite cd mrotcrol fc rcguicremoýi cstebdcmofl ci cd Fcmrctl ]uprcgl I» ;;=-?>-VR

(2>/;=/5??>), V cxtl Ñioml (2>/;=/5??>)

Lrfciefl

fc

de

Dcy

fc [r l fu mto v   vofef y Mlgpctot v  o vofef Deblred (D[MD).

3. RCGSICREMOLIC] CPMDSOFE] Cd Rcndegcitl fc de Dcy I» 2:2>2, scõede quc il cståi mlgprcifofls mlgl rcguicremoýi ejcmte ed penl fc de mlitrobumoýi dls sonuocitcs mlimcptls1  

Des esoniemolics quc sc ltlrnuci plr iemogocitl fc `oal, getrogliol, jeddcmogocitl y ltrls fc scgcaeitc ieturedcze.

 

De Mlgpcisemoýi plr plr Vocgpl fc ]crvomols.

 

De pertomopemoýi ci des utodofefcs fc de cgprcse l de esoniemoýi sustotutlroe.

 

Cd mlstl l vedlr fc des mlifomolics fc trebeal.

 

Cd vedlr fc dls peseacs, socgprc quc cstï supcfotefl e de esostcimoe ed mcitrl fc trebeal y quc rezliebdcgcitc mubre cd rcspcmtovl tresdefl.

 

Dls bocics q qu u c de

cgprcse ltlrnuc e

sus trebeaeflrcs fc

su

prlpoe prlfummoýi, ci mugpdogocitl fc mlivciols mldcmtovls fc trebeal.  

Des pcisolics fc aubodemoýi y/l oivedofcz e mernl fc de cgprcse.

 Esogosgl, il sc cimlitreråi ejcmtls ed penl fc de mlitrobumoýi ed ]CIEVO dls glitls ltlrnefls ed trebeaeflr pere cd mugpdogocitl fc sus deblrcs l mli lmesoýi fc sus juimolics,  tedcs mlgl glvodofef, voåtomls, nes tls fc rcprcscitemoýi, vcstuerol y sogodercs, socgprc quc il scei fc dobrc fospliobodofef fcd trebeaeflr y quc plr su glitl l ieturedcze il rcvcdci cd prlpýsotl fc cvefor de mlitrobumoýi. VROBSVEMOLI OO

[e noie 3

 

Siovcrsofef Eifoie Eifoie Ic Ic stlr Me Me mcrcs Zcde Zcde zqucz

:. OI]MRO[MOÝI Des cgprcses suactes ed penl fc de mlitrobumoýi ed ]CIEVO tocici de lbdonemoýi fc cster oismrotes ci cd pefrýi fc mlitrobuycitcs fcd ]CIEVO, citofef quc fc ljomol cjcmtuerå de oismropmoýi fc des cgprcses quc mugpdocrei mli oismroborsc ci fom`l pefrýi. De oismropmoýi sc rcedoze utodozeifl cd jlrguderol eprlbefl plr cd ]CIEVO, esç mlgl fcbcrå efauitersc dl sonuocitc1  

Mlpoe fcd RSM fc de cgprcse.

 

Mlpoe fc de domcimoe fc juimoliegocitl.

 

Mlpoe fc de csmroture pñbdome fc mlisto  u tumo  ý ýi fc de cgprcse.

 

Ñdtogl [FV ogprcsl.

 Esogosgl, des cgprcses lbdonefes ed penl fc cste mlitrobumoýi fcbcråi mlguiomer ed ]CIEVO de glfojomemoýi l mcsc fc sus emtovofefcs, fcitrl fcd pdezl fc trcoite (=;) fçes fc prlfumofl cstls `cm`ls. Des cgprcses lbdonefes fcbcråi prcsciter ed ]CIEVO uie fcmderemoýi aurefe eiued ci cd gcs fc auiol, ci de quc sc mlisonierå cd iñgcrl fc pcrslied quc deblre ci de cgprcse, esç mlgl ltres oijlrgemolics quc fctcrgoic cd Mliscal Iemolied fcd ]CIEVO. Fom`e fcmderemoýi  aurefe sc prcsciterå prcscite rå ci cd jlrguderol quc prlplrmolierå prlp lrmolierå cd ]CIEVO.

Cstå>.mlijlrgefe plr cd glitl tlted des rcguicremolics ebliefes mefe gcs BE]C OG[LIOBDC FC DEfcMLIVROBSMOÝI mlrrcsplifocitc ed pcrslied fcfomefl e de emtovofef oifustroed y e des deblrcs fc oistedemoýi, rcperemoýi y geitciogocitl.

0. VE]E FC DE MLIVROBSMOÝI Cs fc ;.>3% y sc epdome slbrc cd tlted fc des rcguicremolics fc dls trebeaeflrcs quc deblrci ci des emtovofefcs nrevefes.

VROBSVEMOLI OO

[e noie :

 

Siovcrsofef Eifoie Eifoie Ic Ic stlr Me Me mcrcs Zcde Zcde zqucz

?. [DEQL FC [ENL Cd penl fc de mlitrobumoýi sc rcedozerå fc geicre gcisued fcitrl fc dls progcrls flmc (52) fçes `åbodcs fcd gcs sonuocitc ci quc sc eblierli des rcguicremolics.

5;.

FCMDEREMOÝI EISED ED ]CIEVO

Des cgprcses mlitrobuycitcs ed ]CIEVO cståi lbdonefes e prcsciter uie Fcmderemoýi Aurefe Eiued fc de Mlitrobumoýi `este cd =; fc auiol fc mefe eõl. 

Jlrgetl fc Fcmderemoýi Aurefe

VROBSVEMOLI OO

[e noie >

 

Siovcrsofef Eifoie Eifoie Ic Ic stlr Me Me mcrcs Zcde Zcde zqucz

55. [ENL FC CDCMVRÝIOML]    E

DE

MLIVROBSMOÝI

[LR

GCFOL]

pertor fcd fc d 2;5: sc `e `ebodotefl per pere e ui nrup nrupl l fc mlitrobuycitcs de lpmoýi

fc pener de mlitrobumoýi rcnuder gcisued plr gcfols cdcmtrýiomls.  

[ere `emcr usl fc cstc gcfol fc penl, dls mlitrobuycitcs scdcmmoliefls fcbcråi

oinrcser

dl s

fetls

ci

cd

doih

quc

sc

oifome

e

mlitoiuemoýi1 `ttp1//mlitrobumolics.scieto.cfu.p fu .pc10;;;/mlitrob/Oiomol/  

[rýxogegcitc sc egpdoerå cste lpmoýi e dls fcgås mlitrobuycitcs.

52.

BE]C DCNED



Dcy Il. 2:2>2.



Fcmrctl ]uprcgl I± 5=?-?6-CJ.

VROBSVEMOLI OO

[e noie 0

 

Siovcrsofef Eifoie Eifoie Ic Ic stlr Me Me mcrcs Zcde Zcde zqucz 

  ]eimolics

Veitl de Dcy mlgl cd Rcndegcitl fcd ]CIEVO cstebdcmci quc sli epdomebdcs ed penl fc de mlitrobumoýi des ilrges fcd Mýfonl Vrobuterol. Ci csc scitofl, cd il penl l cd penl cxtc cxtcgplr gplråicl åicl fcd ]CI ]CIEVO EVO ncicreråi ncicreråi cd mlbr mlbrl l fc dls oitcrcscs oitcrcscs glretlrols mlrrcsplifocitcs. Mebc eilter quc ci cstc mesl, ed tretersc fc uie mlitrobumoýi mlitrobum oýi y il uie rctcimo rctcimoýi, ýi, cd oimugpd oimugpdogocit ogocitl l fc penl il mlijonure mlijonurerå rå oijremmoýi trobuteroe ednuie y plr cifc, de epdomemoýi fc uie seimoýi.

VROBSVEMOLI OO

[e noie ?

 

Siovcrsofef Eifoie Eifoie Ic Ic stlr Me Me mcrcs Zcde Zcde zqucz

5=.

ME]L [RÅMVOML1

Ep lrtem oýi oýi e d ]CIEV O

ME]L1 Cgprcses lbdonefes e rcedozer cd eplrtc ed ]CIEVO VROBSVEMOLI OO

[e noie 5;

 

Siovcrsofef Eifoie Eifoie Ic Ic stlr Me Me mcrcs Zcde Zcde zqucz De cgprcse oifustroed ]ei Jreimosml ].R.D. sc cimucitr cimucitre e mlgprcifofe ci de emtovofef emtovo fef geiujemturcre y pcrtcicmc e de fovosoýi fovosoýi 5> fcd MOOS.Eso MOOS.Esogosgl, gosgl, mlgcrmoedoze sus prlpols prlfum tls ci ui gosgl mcitrl fc lpcremoýi, flifc sc cimucitre cd årce efgoiostretove, cd mcitrl fc mlgcrmoedozemoýi y de pdeite fc prlfummoýi. Ci cd gcs fc jcbrcrl fc 2;;: de cgprcse rcjdcae ci su pdeiodde fc rcguicremolics dls sonuocitcs mlimcptls1  

Rcguicremolics fcd pcrslied fcd årce fc prlfummoýi1 ]/. 0,6=;.;2

 

Ogplrtc plr mlifomolics fc trebeal1 :3,60?.63

 

Blils plr eveimc ci prlfummoýi1 5:,630.3;

 

Glvodofef supcfotefe ed treisplrtc1 >,630.2;

 

Rcguicremolics fcd pcrslied fc geitciogocitl1 55,;32.3; Nretojomemoýi cxtrelrfoieroe fcd gcs1 ?,0?0.=>

 

Cd cgpdceflr ils mlisudte so de cgprcse fcbc mlitrobuor ed ]CIEVO, tciocifl ci mucite quc cd prlgcfol fc trebeaeflrcs quc deblrerli ci prlfummoýi ci cd eõl 2;;3 juc fc 2= pcrslies.

]ldumoýi1 Cd ertçmudl 55 fc de ilrge quc rcnude cd ]cieto, eprlbefe plr Dcy IU 2:2>2 (;5/;5/5??6), scõede quc "des cgprcses quc fcserrlddci emtovofefcs oifustroedcs mlgprcifofes ci de Metcnlrçe F fc de MOOS, cståi lbdonefes ed penl fc uie mlitrobumoýi plrmcitued medmudefe slbrc cd tlted fc des rcguicremolics quc penuci e sus trebeaeflrcs. Ved lbdonemoýi fcbcrå scr mugpdofe socgprc quc des cgprcses, fureitc cd eõl eitcrolr (ci cd cacgpdl, 2;;3), `eyei tciofl ui prlgcfol fc gås fc 2; trebeaeflrcs fcfomefls e de emtovofef oifustroed e de quc sc rcjocrc de MOOS.

Fctcrgoiemoýi fcd glitl fc des rcguicremolics suactes e mlitrobumoýi ed ]CIEVO Ci cd mesl pdeitcefl cd prlgcfol fc trebeaeflrcs juc fc 2= pcrslies (2;;3). Ci csc scitofl, tciocifl ci mucite des rcguicremolics cxmduofes fc de mlitrobumoýi ed VROBSVEMOLI OO

[e noie 55

 

Siovcrsofef Eifoie Eifoie Ic Ic stlr Me Me mcrcs Zcde Zcde zqucz ]CIEVO (vcr iugcred 2.6 fcd oijlrgc), de cgprcse sc cimucitre lbdonefe e mlitrobuor sldl plr dls mlimcptls sonuocitcs1  

Rcguicremolics fcd pcrslied fcd årce fc prlfummoýi1 ]/. 60,6=;.;2 +

 

Blils plr eveimc ci prlfummoýi1 5:,630.3;

 

Rcguicremolics fcd pcrslied fc geitciogocitl1 55,;32.3;

 

Besc pere cd eplrtc1 ]/. >3,?65.;2

Mådmudl fc de tese e scr epdomefl pere de mlitrobumoýi ed ]CIEVO ]ocifl de mlitrobumoýi ed ]CIEVO fcd ;.>3% slbrc des rcguicremolics oifomefes, tcicgls dl sonuocitc1

]/. >3,?65.;2 P ;.>3%1 ]/. 3>; 

[rlvosoýi fc de mlitrobumoýi ed ]CIEVO plr cd gcs fc jcbrcrl fc 2;;:  Esocitl mlitebdc1

Cd penl sc cjcmtuerå fcitrl fc dls flmc progcrls (52) fçes `åbodcs fcd gcs sonuocitc e equcd ci quc sc eblici des rcguicremolics. ]c utodoze cd jlrguderol quc prlplrmolie cd ]CIEV ]CIEVOO (ertçmudl 55 fcd Rcndegcitl, Fcmrct Fcmrctl l ]uprcgl IU 5=?-?6- CJ (;0/55/5??6)). ]li epdomebdcs des ilrges fcd Mýfonl Vrobuterol Vrobuterol rcdemoliefes mli de mlbreize fc mlitrobumolics il penefes y dls rcmernls plr  oitcrcscs y gudtes quc cddl ncicrc (ertçmudl 53 fc de Dcy).

VROBSVEMOLI OO

[e noie 52

 

Siovcrsofef Eifoie Eifoie Ic Ic stlr Me Me mcrcs Zcde Zcde zqucz

56. 

MLIMDS]OLIC]

Ducnl fc `ebcr rcedozefl de fc smr op moýi fc des mlitrobumolics deblredcs ed ]CIEVO quc fcbci rcedozer des pcrslies ieturedcs y aurçfomes fcfomefes e des emtovofefcs fc mlistrummoýi c oifustroed, sldl qucfe rcmlgcifer e dls cgpdceflrcs quc mugpdei mli de fcmderemoýi y/l cd penl scnñi sce cd mesl fc fom`es mlitrobumolics e cjcmtls cjcmtls fc cvo cvoter ter scr seim seimoli oliefls efls plr DE ]SIEV l de oistotumoý oistotumoýi i quc dl efgoiostre.



Bucil Sbomegls ed de mlitrobumoýi ed ]CIEVO mlgl trobutls pere ltrls joics ci des muedcs sus mlitrobuycitcs sli pcrslies quc deblrei ci cd scmtlr oifustroed y geiujemturefl fc metcnlrçe F.



Gcfoeitc Gcfoeit c cd mesl plfcgls fctcrgoier de edçmulte, de besc ogpliob ogpliobdc dc fc de mlitrobumolics ed ]CIEVO, de tese fc mlitrobumoýi ed ]CIEVO cs fc ;.>3%.



Des cgprcses cxmcptuefes fc mlitrobuor mli cd ]CIEVO sli equcddes quc sc fcfomei e rcjemmolier, cisegbder prlfumtls quc cståi fcitrl fc dl oifustroe pcrl fc metcnlrçe J, tegboïi des cgprcses quc oifustroedcs quc cd eõl eitcrolr tubl ui pcrslies plr beal fc 2; cgpdcefls.

VROBSVEMOLI OO

[e noie 5=

 

Siovcrsofef Eifoie Eifoie Ic Ic stlr Me Me mcrcs Zcde Zcde zqucz

MLIVROBSMOLIC] ED ]CIMOML Cd ]crvomol Iemolied fc Mepemotemoýi pere de Oifustroe fc de Mlistrummoýi ]CIMOML ]CIMOM L Cs de oistot oistotumoýi umoýi quc tocic plr juimoý juimoýi i

de jlrgemoýi, mepemot mepemotemoýi emoýi

oitcnred,, medojomemoýi y mcrtojomemoýi prljcsolied fc dls trebeaeflrcs fc de emtovofef fcde mlistrummoýi, ci tlfls sus iovcdcs (lpcrerols, tïmiomls y prljcsoliedcs ) y fc rcedozer des oivcstonemolics y cstufols icmcserols

pere etcifcr sus joics.

Besc dcned1 ertomudl=» fcd fcmrctl dcnosdetovl 56> cs ui lrneiosgl pñbdoml fcsmcitredozefl efsmrotl ed scmtlr Zovocife, mlistrummoýi y seicegoc seicegocitl, itl,

plr

dcy

mrcefl

plr

Dcy

I±

25:>=. ]u lrneiozemoýi cstå fcjoiofe ci de Dcy fc Lrneiozemoýi y Juimolics fcd ]CIMOML, eprlbefl gcfoeitc Fcmrctl Dcnosdetovl I± 56>8 esç mlgl e trevïs fc de jusoýi mli cd cx OIOIZ OIOIZO, O, scnñi cd Fcmrctl Dcnosd Dcnosdetovl etovl I± 563 Dcy fcd Oistotutl Iemolied fc Oivcstonemoýi, Oivcstonemoýi,

Ilrgedo Ilrgedozemoýi zemoýi

fc

de

Zovocife.

5.- oitrlfummoýi Mli cd eunc fcd scmtlr mlistrumm mlistrummoýi oýi ci dls ñdtogls eõls cs ogplrteitc mlilmcr des lbdonemolics trobuteroes quc fcbci mugpdor des pcrslies ieturedcs l aurçfomes quc fcserrlddci cste emtovofef citrc des muedcs tcicgls des eplrtcs quc fcbci rcedozer  dls cgpdceflrcs plr dls trebeaeflrcs fc mlistrummoýi movod ed scrvomol iemolied fc mepemotemolics pere de oifustroe fcde mlistrummoýi ” ]CIMOML. CD ]CIMOML tocic mlgl joiedofef de jlrgemoýi mepemotemoýi oitcnred medojomemoýi y mcrtojomemoýi prljcsolied fcdls trebeaeflrcs trebeaefl rcs fc de emtovofef fc de mlistrummoýi ci tlfls sus iovcdcs y esç gosgl rcedoze des oivcstonemolics y cstufols icmcserols pere etcifcr e fom`ls joics. Ci cd prcscitc oijlrg oijlrgc c eiedozercgls dls espcmtls rcjcrofl ed ågbotl fc de epdomemoýi fcde mlistrummoýi ed ]CIMOML de jlrge fc fctcrgoier de besc ogpliobdc de lbdonemoýi fc prcsciter uie fcmderemoýi aurefe plr pertcs fc dls cgpdceflrcs c oimduo oim duorcgl rcglss edn ednuils uils mesl meslss pråmt pråmtoml omlss pere de fctc fctcrgo rgoiemo iemoýi ýi fcd penl fc cst cste e mlitrobumoýi

VROBSVEMOLI OO

[e noie 56

 

Siovcrsofef Eifoie Eifoie Ic Ic stlr Me Me mcrcs Zcde Zcde zqucz

2.- GERML ILRGEVOZL  

Fcmrctl dcnosdetovl i»56> —dcy fc de lrneiozemoýi y juimolics fcd ]CIMOML

fc de jcm`e 53-;:-05.    Ertçmudl ñioml fcd fcmrctl suprcgl sup rcgl i».2:=-02-cjm. i».2:=-02-c jm. Fcde jcm`e ;0-;?-02. ;0-;?- 02.   Dcy i».2:603 —glfojomei y cstebdcmci de tese fc epdomemoýi fc dls eplrtcs ed ]CIMOML‗ fc de jcm`e 5?-;:-?3.   Fcmrctl suprcgl i».;=2-2;5;5 GVM eprucbei cstetutl fcd scrvomol iemolied fc de de ilrgedoze mli, mepemotemoýi c oivcstonemoýi pere de oifustroe fc de mlistrummoýi ” ]CIMOML fc de jcm`e 50-;>-;5.   Fcmrctl suprcgl i».5>?-2;;6 CJ tcxtl ñioml lrfciefl fc de dcy fcd ogpucstl e de rcite fc jcm`e ;0-52-2;;6.   Fcmrctl suprcgli». suprcgli».;;5-2;;=-vo ;;5-2;;=-vo-vovcife -vovcife eprucbei cd tcxtl ñioml fc prlmcfogocitl prlmcfog ocitl efgoiostret efgoiostretovls ovls fcd scrvomol scrvomol iemolied fc ilrgedo ilrgedozemoýi, zemoýi, mepemotemoýi c oivcstonemoýi pere de oifustroe fc mlistrummoýi ]CIMOML fc de jcm`e 56-;5-;=.   Mdesojomemoýi oifustroed oitcriemolied uiojlrgc- mmoou63, mlistrummoýi (tcrmcre rcvosoýi)

=.-EGBOVL FC DE E[DOMEMOÝI Fc emucrfl e dl cstebdcmofl ci cd ertomud25 fcd fcmrctl dcnosdetovl i».56> ci sc cimucitre lbdonefls ed penl fc cste mlitrobumoýi des pcrslie ieturedcs l  aurçfomes quc rcedomci muedquocre fc de emtovofefcs fc de mlistrummoýi mlgprcifofes mlgprcifof ci de fovoso fovosoýi ýi 63fc—mlistrummoýi‗ —mlistr ummoýi‗ scuiofes. e mdesojomemoýi mdesojom emoýi oifustro oifustroed ed oitcriem oitcriemolied oliedesuiojlrgc (MOOS) des iemolics Vcrmc Vcrmcre re rcvosoýi rcvo soýi de gosge quc oimduyc des sonuocitcs mdescs

635; prcperemoýi fcd tcrrcil 632; mlistrummoýi fc cfojomols mlgpdctls y pertcs, lbres fc oinciocrçe movod 63=; emlifomoliegocitl fc cfojomols 636; tcrgoiemoýi fc cfojomols 633; edquodcr fc cquopl fc mlistrummoýi y fcgldomoýi

VROBSVEMOLI OO

[e noie 53

 

Siovcrsofef Eifoie Eifoie Ic Ic stlr Me Me mcrcs Zcde Zcde zqucz

6.-]SACVL] FC DE LBDONEMOLI 6.5 ]SACVL EMVOZL DE ]SIEV cs de citofef cimernefe fc de rcmeufemoýi y josmedozemoýi fc des eplrtemolics ed ]CIMOML, esç mlgl fc de epdomemoýi fc des seimolics prcvostes ci cd mýfonl trobuterol ci mesl fc oimugpdogocitl plr pertc fcd suactl lbdonefl

6.2. ]SACVL [E]OZL ]c cimucitrei suactls ed penl fc de mlitrobumoýi ed ]CIMOML ci medofef ci mlitrobuycitc des pcrslies ieturedcs fc y aurçfomes quc pcrmobei oinrcslsquc plrsli cd fcserrlddl l cacmumoýi fc emtovofefcs mlistrummoýi. Mebc prcmoser suactls fc de mlistrummoýi equcddls mlitrobuycitcs quc fcserrlddei fc mlistrummoýi mli l so cxmdusovofef. OIJLRGC OGOVOFL [LR DE ]SIEV LJOMOLI».5?=-?:-52.;;;; (20-;0-?:) Cste tcifcimoe mlisofcre quc tretåiflsc fc dls submlitretls fc mlistrummoýi dls submlitretostes cste nrevefes mli de mlitrobumoýi ed ]CIMOML plr des sonuocitcs rezlics. fc emucrfl ed ertçmudl 25 fcmrctl dcnosdetovl i»56>,dcy fc lrneiozemoýi y juimolics fc ]CIMOML , fom`e mlistrummoýi nreve ede pcrslies ieturedcs y aurçfomes quc fcserrlddci fcserrlddc i emtovofefcs oifustro oifustroedcs edcs mlgprcifofes ci de nrei fovosoýi 3 fc de mdesojomemoýi oitcriemolied oifustroed uiojlrgl(MMOOS) c de iemolics uiofes plr cd tlted fc fc oinrcsl quc pcrmobei plr ui mlimcptl fc getcroe getcroedcs dcs geil fc lbre nestl ncicredcs forcmmoýi forcmmoýi tïmiome utodofef utodofef y muedquocr ltrl cdcgcitl jemturefl ed mdocitc muedquocre sce cd sostcge fc mlitremmoýi fc lbres.

VROBSVEMOLI OO

[e noie 5:

 

Siovcrsofef Eifoie Eifoie Ic Ic stlr Me Me mcrcs Zcde Zcde zqucz

3.-FCVCRGOIEMOLI FC DE BE]C OG[LIOBDC Cd ertçmudl 25 fcd fcmrctl dcnosdetovl i»56> cstebdcmc cxprcsegcitc dl sonuocitc1 De pcrslies ieturedcs y aurçfomes quc fcserrlddci emtovofefcs oifustroedcs ci de nrei fovosoýi 3 fc de mdesojo mdesojomemoýi memoýi oifustroe oifustroedd oitcriemolied uiojlrgc uiojlrgc fc de es iemolics uiofes, cståi e pener ed ]CIMOML ]CIMO ML ui eplrtc cstebdcmofl cd erto ertomudl mudl3 3 cimo cimosl sl e) lbdonefls fc F.D i»25: i»25:>=ml >=mlimlr imlrfeit feitcsml csmli i cd erto ertoudl2» udl2»fcd fcd fcmrctl fcmrplr  ctl suprcgl i»;5;=>>cj 5: -;0-5?>> y ci cd ertçmudl i»5 fc fcmrctl suprcgl ;=6-0; CJ [lfcgls eprcmoer quc de lbdonemoýi plfrå rcedozer dls eplrtcs ed ]CIMOML il sc cimucitre ci juimoýi e quc de cgprcse sce uie medojomefe cxmdusovegcitc mlgl uie mlistrumtlre soil e de emtovofef rcedozefe plr de gosge, tlfe vcz quc cd `cm`l ogpliobdc quc fctcrgoie cd iemogocitl fc de lbdonemoýi trobuteroe ci cstc mesl, cs de emtovofef fc mlistrummoýi mlistrummoýi rcedozefe plr pcrslie ieturedcs y aurçfomes y cjcmtuefe pere so l pere tcrmcrls mlgprcifofes fcitrl de fovosoýi 63 fc de MOOS.  E`lre boci, cd c d eplrtc ci gcimoýi scnñi cd prlpol tcxtl fcd Ert. 2 25 5 sc f fcbc cbc rce rcedozer  dozer  slbrc de besc fc tlted fc dls oinrcsls, rcde rcdemoliefls moliefls mli des emtovofefcs emtovofefcs fc mlistrummoýi quc sc pcrmobei plr mlimcptl fc getcroedcs, geil fc lbre, nestls ncicredcs, y muedquocr ltrl cdcgcitl jemturefl ed mdocitc muedquocre quc sce de mlitretemoýi fc lbres. Dl eitcrolr sc vc rcejorgefl plr cd `cm`l fc quc ci de pråmtome plfrçei prcscitersc sotuemolics quc mlijonurerçei supucstls mlijosmetlrols ci mesls ci dls quc sldl cd 5;% fc dls oinrcsls fc uie cgprcse prlvcinei fc de emtovofef fc de mlistrummoýi trobutåiflsc cd tlted fc oinrcsls oifcpcifocitcgcitc fcd topl fc emtovofef fcd mued `eye prlvciofl fom`l oinrcsl.

:.-VE]E FC MLIVROBSMOÝI ED ]CIMOML De tese e epdomersc slbrc de besc ogpliobdc cquovedc e ;.2% de gosge quc rcsudte epdomebdc fcsfc cd eõl 5??:. Mýfonl trobuterol1 >;=5

>.- IEMOGOCIVL FCDE LBDONEMOÝI VROBSVEROE Ci jcm`e quc sc pcrmobei dls oinrcsls l sc cgote cd mlgprlbeitc fc penl, tocic meråmtcr fc meimcde tlrol y cs fc pcrolfomofef gcisued, sce cstc plr dls mlimcptls fc1    Efcdeitls   Vlted vedlrozefl VROBSVEMOLI OO

[e noie 5>

 

Siovcrsofef Eifoie Eifoie Ic Ic stlr Me Me mcrcs Zcde Zcde zqucz  

Zedlrozefl l pcroýfoml

VROBSVEMOLI OO

[e noie 50

 

Siovcrsofef Eifoie Eifoie Ic Ic stlr Me Me mcrcs Zcde Zcde zqucz  

Rcgbldsls y ltrls

0.- JLRGE _ DSNER FC [ENL Dls suactls e cjcmtuer cd penl fc de mlitrobumoýi ed ]CIMOML fcbcråi rcedozer  fom`l penl e trevïs fcd jlrguderol I» 5::2 nuçe pere penl verols ci cd beiml fc de iemoýi y ci des encimoes beimeroes eutlrozefes, fc emucrfl ed mrlilnrege fc lbdonemolics trobuteroes eprlbefe plr de ]SIEV. Cd mýfonl pere cjcmtuer cd penl fc des mlitrobumolics cd >;=5.

?.- ]EIMOLIC] E[DOMEBDC] CI CI ME]L FC OIMSG[DOGOCIVL CI CD [ENL [ere cjcmtl fc des seimolics plr glre u lgosolics ci cd penl fc dls eplrtcs ci cd ]CIMOML sli fc epdomemoýi des fosplsomolics pcrtoicitcs fcd mýfonl trobuterol. Cs fc oifomersc quc ci de gcfofe quc il sc e rcnudefl de lbdonemoýi fc prcsciter  uie fcmderemoýi fctcrgoiefe pere fom`e mlitrobumoýi soil quc sc cstebdcmc cd penl forcmtl plr pertc fc dls mlitrobuycitcs il scrå epdomebdc de seimoýi ci cd Ert. I»5>: iugcred 5 fcd mýfonl trobuterol ci cd mesl quc oimugpdocrei mli cd penl fcitrl fc de VROBSVEMOLI OO [e noie 5?

 

Siovcrsofef Eifoie Eifoie Ic Ic stlr Me Me mcrcs Zcde Zcde zqucz jcm`e cstebdcmofe ci cd mrlilnrege eprlbefl plr de ]SIEV, il lbsteitc, cd penl rcedozefl fc geicre cxtcgplråice ncicre de epdomemoýi fc oitcrïs glretlrols fc emucrfl mli de tese fc oitcrïs glretlrol VOG voncitc

5;.- LBDONEMOÝI LBDONEMOÝI FC [RC]CIVER [RC]CIVER DE FCMDEREMOÝI FCMDEREMOÝI ASREFE FC LBRE] ]c cstebdcmc de lbdonemoýi fc prcsciter ed ]CIMOML uie fcmderemoýi aurefe fc lbres fc geicre mliauite mli de prcscitemoýi fc de fcmderemoýi eiued fcd ogpucstl e de rcite fc emucrfl ed jlrgetl fc oismropmoýi e fom`e citofef.

55.-FCFSMOBODOFE 55.-FCFSMOB ODOFEF F FCD [ENL OG[SC]VL EDE RCIVE

FCD ]CIMOML ]CIMOML MLIVRE MLIVRE CD

De eplrtemoýi ed ]CIMOML mlistotuyc mlistotuyc ui nestl fcfumobdc pere cjcmtls fc fctcrgoiemoýi fcd ogpucstl e de rcite fc tcrmcre metcnlrçe fc emucrfl ed fospucstl ci cd Ert. 25 fcd fcmrctl dcnosdetovl I» 56> y cd Ert. Oimosl B fcd VSL fc de dcy fcd ogpucstl e de rcite eprlbefl plr fcmrctl suprcgl I» 5>? ” 2;;6.CJ/;0 ” 52 ” ;6.

52.-FCZLDSMOLI FC [ENL] OIFCBOFL] CI CPMC]L MLIVROBSMOÝI ED ]CIMOML

FC DE

Fc emucrfl ed prlmcfogocitl I» 5: fcd tcxtl ñioml fc prlmcfogocit prlmcfogocitls ls efgoiostretovls VS[E fc de ]SIEV, pere cd mesl fc de prcscitemoýi fc sldomotufcs fc fcvldumolics plr penls oifovofuls l ci cxmcsl mlrrcsplifocitc e de mlitrobumoýi ed ]CIMOML, de ]SIEV civçe cd oijlrgc tïmioml y de flmugcitemoýi sustcite sust citeflre flre mlrrcsplifo mlrrcsplifocitc citc ed ]CM ]CMOML OML,, uiof uiofef ef quc sc cime cimerner rnere e fc de fcvldumoýi. Cd trågotc fcvldumoýi sc rcedozerå mlijlrgc ed prlmcfogocitl I» 3 fcd VS[E fcd ]CIMOML, eprlbefl plr cd fcmrctl suprcgl I» ;;5- 2;;=- ZOZOCIFE 56-;5-;=.

5=.-MEG[L FC E[DOMEMOÝI Cs epdomebdc e dls Mlitretls fc Mlistrummoýi Mlitretls fc mlistrummoýi mcdcbrefls ci cd tcrrotlrol iemolied l il y muyl scrvomol sce cgpdcefl ci iucstrl peçs c oifcpcifocitc ed duner flifc sc pcrmobei dls oinrcsls. VROBSVEMOLI OO

[e noie 2;

 

Siovcrsofef Eifoie Eifoie Ic Ic stlr Me Me mcrcs Zcde Zcde zqucz Des emtovofefcs e cacmutersc, lbactl fcd mlitretl fcbcråi cimlitrersc cigermefls ci cd mdesojomeflr MOOS-63 Mlistrummoýi, voncitc `este cd 2?/;5/2;5;8 e pertor fcd =;/;5/2;5; sc cimucitrei ci voncimoe cd MOOS scmmoýi J Mlistrummoýi Rcvosoýi OZ. Mebc prcmoser, quc sli suactls fc de Mlitrobumoýi ed ]CIMOML, equcddls mlitrobuycitcs quc fcserrlddci emtovofefcs fc mlistrummoýi mli l soi cxmdusovofef.

56.-MRLILNREGE FC LBDONEMOLIC] - CACRMOMOL 2;5: Cs epdomebdc e1

VROBSVEMOLI OO

[e noie 25

 

Siovcrsofef Eifoie Eifoie Ic Ic stlr Me Me mcrcs Zcde Zcde zqucz

53.-CPONOBODOFEF FC [ENL FC DE D E MLIVROBSMOÝI ED ]CIMOML Cd penl cs cxonobdc e pertor fcd fçe sonuocitc fc de jcm`e fc vcimogocitl, quc fosplic cd mrlilnrege fc penls - ]SIEV.

5:.-DSNERC] FC [ENL Beiml fc de Iemoýi y Beime [rovefe ejodoefe e de mefcie fc Rcmeufemoýi ]SIEV, e trevïs fcd ]ostcge [enl Jåmod.

5>.-MÝFONL VROBSVEROL Beiml fc de Iemoýi y [enl Jåmod. Beime [rovefe ejodoefe e de mefcie fc Rcmeufemoýi ]SIEV, e trevïs fcd ]ostcge

[ere cd penl fc de Mlitrobumoýi ed ]CIMOML sc fcbc utodozer cd mýfonl1 >;=5 FEVL]

MÝFONL

[enl fc Vrobutl - ]CIMOML [enl [e nl fc Jrem Jremmo moli lieg egooci cittl - ]CIM ]CIMOM OML L

>;=5 >;=5 >;=5

Fcmrctl Dcnosdetovl I± 060

>;==

RCJV - Dcy I± 2>=66

>;=:

]CE[ - Fcmrctl Dcnosdetovl I± ?56

>;=>

RC]OV - Dcy I± 2>:05

>;=0

Ltres Gudtes

:3=3

VROBSVEMOLI OO

[e noie 22

 

Siovcrsofef Eifoie Eifoie Ic Ic stlr Me Me mcrcs Zcde Zcde zqucz

50.-FCMDEREMOÝI ASREFE Fcmrctl ]uprcgl I» 2:=-02-CJM) (Lbdonemoýi Jlrged)

Dls suactls ed penl fc de Mlitrobumoýi ed ]CIMOML, cståi lbdonefls e mugpdor ci jlrge eiued mli de prcscitemoýi fc de Fcmderemoýi Aurefe fc [crslies Ieturedcs y Aurçfomes quc fcserrlddei de emtovofef fc de mlistrummoýi. De prcscitemoýi fc de Fcmderemoýi Aurefe ed ]CIMOML, vcimc ci de gosge lplrtuiofef fc vcimogocitl fc de Fcmderemoýi Eiued fcd ogpucstl e de). Rcite (scnñi mrlilnrege fc ]SIEV) De Fcmderemoýi Aurefe csterå rcjcrofe e des lpcremolics nrevefes fureitc cd cacrmomol eitcrolr ed fc de prcscitemoýi1 RSBRL O

RSBRL OO

RSBRL OOO Mlisonier gci cisu sued ed

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mli mlist stototuof uofes es

Rcdemoý Rcd emoýi i fc Lbre Lbress muye plr cd vedlr vcite fc de jcm`e fc oiomol sc fol je jemt mture ure cgo cgototofe fe ejc ejcmt mtes es e Fetls fcd Mlitrobuycitc.

fureitc fcmderefl.

cd

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ed

ncicrefes cd

pcrolfl

trobuterol mloimofcitc mli dl escitefl ci cd Rcnostrl fc Zcites.

VROBSVEMOLI OO

[e noie 2=

 

50.5JCM@E] FC ZCIMOGOCIVL [ERE DE [RC]CIVEMOÝI FC DE FCMDEREMOÝI ASREFE EISED ED ]CIMOML EÕL 2;5:

ÑDVOGL FÇNOVL FCD RSM

JCM@E FC ZCIMOGOCIVL

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26 fc gerzl fcd 2;5>

5

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Bucils mlitrobuycitcs

;> fc ebrod fcd 2;5>

Rcsldumoýi fc ]upcroitcifcimoe I± =0;-2;56/]SIEV.

 

5?.- ME]L [REMVOMLFC FCVCRGOIEMOLI ED ]CIMOML ME]L [REMVOML 5 [DEIVCEGOCIVL De cgprcse mlistrumtlre SEIMZ ].E.M. tocic e su mernl uie pdeiodde fc 2; trebeaeflrcs fc mlistrummoýi movod sc sldomote fctcrgoier cd glitl fc de mlitrobumoýi pere cd pcrolfl sctocgbrc fcd 2;5: fc emucrfl e dls sonuocitcs fetls1

FEVL]1 Oinrcsls pcrmobofls plr cd mlistrumtlr ci cd gcs fc enlstl fcd 2;5:1  Getcroedcs ]/. 5:,;;; Geil fc lbre ]/. 6,;;;  Nestls ncicredcs ]/. =,;;;  Forcmmoýi tïmiome ]/. 2,3;;  Ltrls ]/. 3,;;;  

Vlted fc oinrcsls

]/. =;,3;;

]LDSMOLI1 De besc ogpliobdc ci cd prcscitc mesl csterå fctcrgoiefe plr cd tlted fc oinrcsls pcrmobofls cd tlted fc oinrcsls cd mlistrumtlr mlimcptl fc getcroedcs, getcroed cs, plr geil fc lbre, nestls pcrmobofls ncicredcs, plr forcmmoý forcmmoýi i tïmiome plr y ltrl cdcgcitl jemturefl ed mdocitc , muedquocre quc cd sostcge fc mlitretemoýi fc lbre quc ci cstc mesl cquovedc e ]/. ==,3;; slbrc de besc ogpliobdc epdomercgls de tese fc de mlitrobumoýi1 ]/. =;,3;; x ;.2% 7 ]/. :5.;;

Ci mliscmucimoe cd glitl e pener plr mlimcptl fc ]CIMOML cquovedc e ]/. :5.;;

 

ME]L [RÅMVOML I»2 [deitcegocitl De cgprcse fc Oin. Movo Movodd —prlycmtl ].R.D— toc tocic ic e mernl uie pdeiodde fc =; trebeaeflrcs fc mlistrummoýi movod. ]c sldomote fctcrgoier cd glitl fc de mlitrobumoýi pere cd pcrolfl sctocgbrc fc 2;5> fc emucrfl e dls sonuocitcs fetls1 Fetls1 Oinrcsls pcrmobofls plr de cgprcse ci cd gcs fc sctocgbrc fc 2;5>1 Getcroedcs =3,;;; Geil fc lbre >,;;; Nestls ncicredcs 5,;;; F Lotrrclmsmoýi tïmiome Vlted fc oinrcsls

: ?,,; ;; ;; ; 30,;;;

]ldumoýi1 De besc ogpliobdc ci cd prcscitc mesl csterå fctcrgoiefe plr cd tlted fc oinrcsls pcrmobofls pcrmobof ls plr cd mlistrumtlr plr mlimcptl fc getcroedcs, geil fc lbre, nestls ncicredcs, forcmmoýi tïmiome, utodofef y muedquocr cdcgcitl jemturefl ed mdocitc, muedquocre quc sce cd sostcge fc mlistrummoýi fc lbres, quc ci cstc mesl cquovedc e ]/.30,;;;.;; ]lbrc de besc ogpliobdc epdomercgls de tese fc de mlistrummoýi1 ]/.30,;;;.;; x ;.2% 7 55: Ci cstc cstc mesl mesl,, cd g glitl litl e pener plr plr mli mlimcpt mcptl l fc ]C ]CIMO IMOML ML cquo cquovedc vedcitc itc e 1 ]/.55:.;;.;;