Ipratropium Bromide Plus Salbutamol

Generic Name (Brand name)

Mechanism of Action

Generic Name: Ipratropium + Salbutamol

Combivent UDVs contain two active ingredients, ipratropium bromide and salbutamol sulphate, both of which are bronchodilators. Combivent UDVs are used to treat people suffering from chronic obstructive pulmonary disease, who require regular treatment with ipratropium and salbutamol.

Brand Name:

Dosage and Frequency:

Nebulization Q4 Drug Class: Anti-asthmatic and COPD Preparations.

Salbutamol belongs to a group of medicines called short-acting beta 2 agonists. It works by

Date Ordered/ Administe red February 26, 2015

Indications

Salbutamol and ipratropium belong to the family of medications known asbronchodilators. Together, they are used to treat chronic obstructive pulmonary disease (COPD), a chronic lung disease that makes it difficult to breathe. These medications work in different ways to open the airways and make breathing easier.

Contraindications

Adverse effects

Allergy to ipratropium Coughing bromide or related headache medicines, eg atropine. nausea Change in sense of taste Fast, abnormal heart dizziness rhythms dryness of mouth (tachyarrhythmias). nervousness tremor Heart disease Angioedema (swelling characterised by of the face,lips, or thickening of the eyelids) internal heart muscle bronchospasm, and a blockage inside paradoxical or the heart (hypertrophic hypersensitivity obstructive induced(shortness of cardiomyopathy). breath;wheezing) chest discomfort or This medicine is not pain recommended for irregular children and heartbeat adolescents under 12 oropharyngeal years of age, as there is edema (swelling of the no information mouth or throat) regarding its safety and skin rash

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acting on receptors in the lungs called beta 2 receptors. Stimulation of these receptors causes the muscles in the airways to relax, allowing the airways to open. Ipratropium bromide is a type of medicine known as an antimuscarinic bronchodilator. It works by blocking different types of receptors, called muscarinic receptors, which are found on the muscle surrounding the airways in the lungs. Stimulation of these receptors by a natural chemical called acetylcholine normally causes the muscle in the airways to contract,

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and this makes the airways narrow. Depending on how much the receptors are stimulated, this can cause difficulties breathing, as is seen in asthma and bronchitis. As ipratropium blocks the receptors, it stops the action of acetylcholine and allows the airways to open, making it easier to breathe.