Hormones

]Heart

Secreted hormone

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Abbre viatio n

Atrialnatriuretic peptide

ANP

Brain natriuretic peptide

BNP

From cells

Effect

Reduce blood pressure by: Cardiac myocytes reducing systemic vascular resistance, reducing blood water, sodium and fats (To a lesser degree than ANP) reduce blood pressure by: Cardiac myocytes

reducing systemic vascular resistance, reducing blood water, sodium and fats

Adipose tissue Secreted hormone

From cells

Effect

decrease of appetite and increase of metabolism. Leptin (Primarily)

Adipocytes

adiponectin

Adipocytes

Signals to eat more when fat storages are low and eat less when fat storages are high

glucose regulation and fatty acid oxidation.

Liver Abbrevia tion

Secreted hormone

Insulin-like growth factor (or somatomedin) (Primarily)

From cells

Effect

insulin-like effects IGF

Hepatocytes regulate cell growth and development vasoconstriction

Angiotensinogen and angiotensin

Hepatocytes

Thrombopoietin

Hepatocytes

release of aldosterone from adrenal cortex, its a dipsogen. [3]

stimulates megakaryocytes to produce platelets

Kidney Secreted hormone

Renin (Primarily)

Erythropoietin (EPO)

Cacitriol (1,25 dihydroxyvitamin D3) Thrombopoietin

From cells

Effect

Juxtaglomerular cells

Activates the renin-angiotensin system by producing angiotensin I of angiotensinogen

Extraglomerular mesangial cells

Stimulate erythrocyte production

Active form of vitamin D3 Increase absorption of calcium and phosphate from gastrointestinal tract and kidneys ,inhibit release of PTH stimulates megakaryocytes to produce platelets[3]

PDGFs are mitogenic during early developmental stages, driving the proliferation of undifferentiated mesenchyme and some progenitor populations. During later maturation stages, PDGF signalling has been implicated in tissue remodelling and cellular differentiation, and in inductive events involved in patterning and morphogenesis.

EGF results in cellular proliferation, differentiation, and [5] survival. EGF is a low-molecular-weight polypeptide first purified from the mouse submandibular gland, but since then found in many human tissues including submandibular gland, parotid gland. Salivary EGF, which seems also regulated by dietary inorganic iodine, also plays an important physiological role in the maintenance of oro-esophageal and gastric tissue integrity. The biological effects of salivary EGF include healing of oral and gastroesophageal ulcers, inhibition of gastric acid secretion

NGF is critical for the survival and maintenance of sympathetic and sensory neurons. Without it, these neurons [5] undergoapoptosis. Nerve growth factor causes axonal growth.

It also functions as a signaling molecule