Se encuentra por todo el cuerpo. Comprende unas glándulas endocrinas principales: • • • • •
La pituitaria, La tiroides, Las suprarrenales, El páncreas, Las gónadas.
Las glándulas endocrinas son de secreción interna, ya que carecen de conductos propios.
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• Son unas sustancias químicas que circulan por la sangre. • Se distribuyen por todo el cuerpo produciendo efectos sobre determinadas células. •
Producción de las hormonas está controlada por un sistema de retroalimentación negativa
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Las hormonas se componen de moléculas derivadas de los esteroides, de las proteínas o de la tirosina (un aminoácido). Solamente llegan a ser activas cuando están adosadas a un receptor específico de la membrana celular o dentro de la célula. Las hormonas derivadas de
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El crecimiento y desarrollo. Reproducción Las características sexuales. El uso y almacenamiento de energía
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El hígado y los riñones desempeñan un papel fundamental en la depuración y excreción de estas hormonas,
EJEMPLO: La vida media de la prolactina es de 12 minutos; la de la LH y FSH es cercana a la hora, mientras que la HCG tiene una vida media de varias horas.
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FÁBRICA DE HORMONAS. Producen las hormonas son:
Glándulas endocrinas: • • • •
HIPOTALAMO. PINEAL. TIROIDES. TIMO.
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HORMONAS QUE PRODUCE LA ADENOHIPOFISIS:
1) Hormona del crecimiento (HG): O rigen: Secretada por las células Origen células acidofilas acidofilas - somatotropas. acidofilas Ó rgano blanco: Influye sobre todas las células de cuerpo. Órgano Función: Afecta el metabolismo intermedio y junto con las hormonas del
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HORMONAS QUE PRODUCE LA ADENOHIPOFISIS: 3) Cortic Corticotropina otropina (ACTH) O rigen: Secretada por las células basofilas ---- corticotropas Origen Ó rgano blanco: Actúa sobre las suprarrena Órgano las glándulas suprarrenales, suprarrenalles, es, el cortisol.
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HORMONAS QUE PRODUCE LA ADENOHIPOFISIS:
5) Gonodotropica (FSH – LH) Origen: Son secretadas por las células basofilas gonadotropicas
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2. Neurohi Neurohipófisis: pófisis: Ubicación: Esta formada por tejido nervioso y unido al cerebro por estructuras alargadas, fina y delicada, llamada tallo de la hipófisis. hi pófisis.
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