Herencia Extracromosomica

 

Agrghmno gxtromrd`dsý`nmo ]usoho Jdhzïbgz Lnvnsnýh Mntdjghîtnmo Mntdjghîtnmo--NNCMG Fomubtol lg Mnghmnos

 

Agrghmno gxtromrd`dsý`nmo 

Urïmtnmo`ghtg tdld gb OLH mgbubor gstï bdmobnzold gh gb hûmbgd.

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Bo trohs`nsnýh jghîtnmo sg coso gh bds prnhmnpnds y bgygs lg bo agrghmno.

 

Gfgmtd `otgrhd 

Gb OLH hd nhnmno gb lgsorrdbbd lg bos moromtgràstnmos cndbýjnmos gh ousghmno lg bds lg`ïs md`pdhghtgs mgbuborgs OLH humbgor 

 

Gfgmtd `otgrhd 

Gb ývubd gs qunîh opdrto gb mntdpbos`o (drjohgbds y dtros `dbîmubos).

 

Gfgmtd `otgrhd 

Bds gfgmtds fghdtàpnmds puglgh sgr `dlnfnmolds pdr gb `glnd gh fdr`o mdhsnlgrocbg. Gh bolgb `ns`o uho fughtg n`pdrtohtg gfgmtdmîbubo o`cnghtob gstï gh gb mntdpbos`o qug rdlgo gb hûmbgd

 

Gfgmtd `otgrhd 

Wh `ns`d jghdtnpd puglg ‒fuhmndhor‐ lnstnhtd gh lnfgrghtg mntdpbos`o

 

Gfgmtd `otgrhd 

Bds gfgmtds prdlumnlds pdr gb mntdpbos`o gh bo gxprgsnýh lgb jghdtnpd, sdh bds bbo`olds `otgrhds

 

Moromtgràstnmos lg bo agrghmno gxtromrd`dsý`nmo 

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Bds md`pdhghtgs mntdpbïs`nmds lgb ývubd puglg nhfbunr gh bo gxprgsnýh lg bds jghdtnpds jghdtnpdsGfgmtd @otgrhd Mdhtrncuyg gb OLH lg bds drjohgbds mntdpbïs`nmds

 

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Gfgmtd @otgrhd iuahngbbo @ornpdso Gpagstno iua  iuahng hngbbo bbo (borvos pnj`ghtolos O0qunhurghnho9 O0qunhurghnho9 oo0 hd pnj.) Oo x oo Oo x?oo oo ?Oo; ]nh g`corjdbosgbborvos fghdtnpd gsbopnj`ghtold. Ob `oluror sdbd ° sdh pnj`ghtolos

 

Oo♅

oo♃ o

O

O

o

o o

oo

 

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Gb mntdpbos`o lgb ývubd lg bo `olrg agtgrdmnjdto ao mdhtrncunld mdh gb pnj`ghtd qunhurghnho qunhurghnho, , snh n`pdrtor qug jghdtnpd prgsghtgh. Nhnmnoh gb lgsorrdbbd md`d borvos pnj`ghtolos o pgsor lg sgr oo

 

Gfgmtd @otgrhd 

Gb gfgmtd lgb mntdpbos`o `otgrhd puglg sgr pgr`ohghtg.

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Gk. Moromdb Bn`hgo (ghrdbbo`nghtd lgrgmao 0L y aomno bo nzqungrlo0 ll)

Ll x ll Gb sghtnld lg ghrdbbo`nghtd sg lgtgr`nho pdr gb jghdtnpd `otgrhd

 

Gfgmtd @otgrhd  Bn`hgo 

Ll x Ll L

L LL l Ll

Lgsmghlghmno tdlo lgxtrdjnro o pgsor lg ll l Ll ll

nzqungrlo

 

 Bn`hgo  Bn`hgo Gfgmtd `otgrhd gh Ývubd L Mnt ntdp dpbo bos` s`o o ll opdrto fomtdr qug nhancg bo gxprgsnýh lgb jghdtnpd rgmgsnvd ll Gh bo snjunghtg jghgromnýh lg outdfgmuhlomnýh lg F? sg rgstocbgmg prdpdrmnýh =;?

morgmg lg fomt

snhnstrýjnrd ]njunghtg jghgromnýh outdfgmuhlomný h tdlds td lds jnr jnro oh o b o l grgma grgmao, o, gh bo pr ýxn`o prýxn `o sg rgstocbgmg prdpdrmnýh prdpdrm nýh =;? =;?

 

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Gb ghrdbbo`nghtd lgb moromdb dmurrg gh bos prn`gros lnvnsndhgs mgbuborgs lgb ývubd fgmuhlold, y gb sghtnld lg lgspbozo`nghtd o bo lgrgmao d o bo nzqungrlo gsto lgtgr`nhold pdr gb jghdtnpd `otgrhd.

 

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Gstds gkg`pbds `ugstroh gb gfgmtd `otgrhd trohs`ntnld o trovîs lgb mntdpbos`o lgb ývubd toh sýbd uho jghgromnýh, yo qug gh bo snjunghtg, gb mntdpbos`o lgb ývubd sg mdhstntunrï lg omugrld ob hugvd jghdtnpd `otgrhd.

 

Agrghmno gxtromrd`dsý`nmogxtromrd`dsý`nmoAgrghmnoMbdrdpbostds  @nr  @ @nrocnbns @nrocnbns kobopo nro ocn cnbn bns s kobopo  kob  k obop opo o (vorngjolos, adkos

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vgrlgs y cbohmos)

 

Agrghmno gxtromrd`dsý`nmoMbdrdpbostd Ubohtos vorngjolos 

]n bos fbdrgs gstïh gh bo ro`o fg`ghnho lg adkos vgrlgs tdlo bo lgsmghlghmno sgrï vgrlg.

 

Agrghmno gxtromrd`dsý`nmoMbdrdpbostd Ubohtos vorngjolos 

]n bo ro`o fg`ghnho gs lg adkos cbohmos tdlo bo lgsmghlghmno sgrï cbohmo y voh o `drnr pdr fobto lg fdtdsàhtgsns.

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]n bo ro`o fg`ghnho gs lg adkos sgrï vorngjolos tdlo bo lgsmghlghmno vorngjolo

 

Mbdrdpbostd Drjohgbd mntdpbos`ïtnmd lg bos pbohtos gumorndtos OLH mbdrdpbostd mnrmubor ?35-355 Ic

 

OLH Mbdrdpbostd    

?35 ?35--355 icp Mdhtnghg sgmughmnos NS Borjg ]nhjbg Mdpy (B]M) ]`obb ]nhjbg Mdpy (]]M)

 

OLH Mbdrdpbostd  

Ghtrg ?=5 ?=5--?75 jghgs gstrumturobgs Molo mbdrdpbostd tnghg ?5 ” ?55 ?55 mdpnos

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lg OLH Molo mîbubo tnghg 35 ” 75 75 mbdrdpbostd

 

@opo jghgs mbdrdpbostd

 

@opo jghgs mbdrdpbostd

Fg Fgoturg oturg Igy

Mbdrdpbostd `oàz

Mbdrdpbostd orrdz

Anjabnjat

]mo ]mobg bg ; ICU ICU

 

 OLH @N\DM @N\DMDHLSNOB DHLSNOB @N\DMD HLSNOB

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OLH mnrmubor ldcbg agcro, snh prdtgàhos osdmnolos @ntdmdhlrno 5.7 · Q 3 o 7 ·

 

 OLH @N\DM @N\DMDHLSNOB DHLSNOB @N\DMD HLSNOB

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Gxnstg lg 3 o ?5 mdpnos pdr `ntdmdhlrno y puglgh aocgr aosto ?55.555 `ntdmdhlrnos pdr mîbubo ]g agrglo pdr bàhgo `otgrho

 

 OLH @N\D @N\DMDHLSNOB MDHLSNOB @N\DMD HLSNOB 

Gsto tdtob`ghtg sgmughmnold lgslg bo

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lîmolo lg bds 15 Jghd`o cïsnmo`ghtg mdlnfnmohtgs gh `o`àfgrds (snh nhtrdhgs) nhtrdhgs oprdxn`olo`ghtg ?6 Ic) lg

 

Drjo rjohnz hnzo omnýh lg rg rgjnýh jnýh L bddp y jg j ghg hgs s olyomghtgs Vgrtgcrolds (gxmgptd ovgs) Mnt.c

Ovgs \ar. Ur.

\ar. Ur. L- bddp

HL6

G

L- bddp

F ?3] rSHO

?3] rSHO

Nhs hsg gmt mtds ds y Mru rust sto omg mgds ds ?3] rSHO

L- bddp

N_@

HL3

 

Gxmgpmndhgs Mnt.c

L- bddp

B\ar. Ur.F

?3] rSHO

Soh o mot mot gs c n oh o  HL6

V U

L- bddp

F  HL7

M. gbgj gbgjohs ohs  HL?

 Os  O s m or ornn s s u u `

^ H

L- bddp

?3] rSHO

 

Sgjn jnýh ýh lg md mdht htrd rdbb Ld`nhnd mghtrob

Ld`nhnd nzqungrld

Ld`nhnd lgrgmad

mdhsgrvold 3

?

DA

Mnt. c  t    S

 t    S  H  H O O

7„

L-bddp

 t    a     p r  r   d

Urn`gr  ? \ar-B?7>36 7' JOO\\MMMMJJ\M\\J\OOOMM =' 3 LBA-?6=5% Fghdtnpd

:5%

75%

15% Fghdtnpd

?55%

 

 OUBNMOMNDHG]

Lgtgmmnýh lg obtgromndhgs agrglntornos  Lnojhýstnmd lg porghtgsmd 

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Gstulnds pdcbomndhobgs (jrold lg agtgrdmnjdsns, fbukd jîhnmd y fnbdjgdjrofno)

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Gstulnds lg `nmrd y `omrdgvdbumnýh

 

VOSNOCNBNLOL JGHG\NMO @oydr pdsncnbnlol lg oloptomnýh oloptomnýh.. Muohld bos pdcbomndhgs sg froj`ghtoh sg pngrlg vornocnbnlol gb lns`nhuyg hû`grd ou`ght ou`ghtïhld ïhld ghldjo`no.

bo

jghîtnmo, gfgmtnvd,

prdcocnbnlol

lg

 

N

NN NNN

Uornghtgs qug md`portgh jghd`o `ntdmdhlrnob Uornghtgs qug hd md`portgh jghd`o `ntdmdhlrnob

 

Jghîtnmo lg bo mdhsgrvomnýh

 

JGHG\NMO LG BO MDH]GSVOMNÝH 

Gs bo opbnmomnýh lg bo jghîtnmo poro prgsgrvor bos gspgmngs md`d ghtnlolgs lnhï`nmos mopomgs lg oloptorsg o bds mo`cnds o`cnghtobgs.

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Nhmbuyg gb `ohgkd jghîtnmd lg bos pdcbomndhgs pgqugÿos Sgsdbumnýh lg nhmngrtds toxdhý`nmos

 

JGHG\NMO LG BO MDH]GSVOMNÝH 

Lgfnhnmnýh lg uhnlolgs lg `ohgkd gh bos gspgmngs.

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Opbnmomndhgs fdrghsgs Md`prghlgr bo cndbdjào lg bos

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pdcbomndhgs y lg bos gspgmngs

 

Jghîtnmo lg bo mdhsgrvomnýh

 

Ohïbnsns jghîtnmd mdh `ormoldrgs gxtrohumbgorgs 

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Wrsus o  orm ormtds rmtds tds lg bo ]g ohobnzordh dsds Wrsus pdcbomnýh lg Crghto (H0= o ?5), rgjnýh

l `ntdmdhlrnob. ]gbddp md`porý mdh gkg`pborgs lg Su`ohno y Hdrtg O`îrnmo. ]g nhvgstnjd bds prnhmnpobgs jîhgrds lg pbohtos prgsghtgs gh bo lngto mdh prn`grs rcmB lgb mbdrdpbostd.

 

Ohïbnsns jghîtnmd mdh `ormoldrgs gxtrohumbgorgs

 

]gmughmno pormnob lg bo rgjnýh lg bddp mdh gkg`pborgs lg bos =  pdcbomndhgs

Lnfgrghmnos ghtrg pdc. Gurdpgos y O`grnmohos Mo`cnd Mo` cnd gh bo bo pdc pdc Su` Su`oh ohno no Mo`cnd gh bos = pdcbomndhgs

 

Agrghmno gxtromrd`dsý`nmo 

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Bds md`pdhghtgs mntdpbïs`nmds lgb ývubd puglg nhfbunr gh bo gxprgsnýh lg bds jghdtnpds humbgorgs humbgorgs--Gfgmtd @otgrhd Gb OLH lg bds drjohgbds mntdpbïs`nmds gs uh `ormoldr olgmuold poro ohobnzor vornocnbnlol jghîtnmo (porghtgsmd, pdcbomndhob y gvdbutnvd).

 

Mrntgrnds poro lnsmrn`nhor bo agrghmno gxtromrd`dsý`nmo 

Gxnstg objuho lnfgrghmno ghtrg bds mruzo`nghtds rgmàprdmds y snjug bo agrghmno lgb`otgrho morïmtgrsnh ghn`pdrtor fdr`o mdhtnhuo pdr bo bàhgo muob sgo gb jghdtnpd sgo gb jghdtnpd

 

Mrntgrnds poro lnsmrn`nhor bo agrghmno gxtromrd`dsý`nmo 

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Uuglg mo`cnorsg gb morïmtgr lg fdr`o pgr`ohghtg pdr `glnd lg ojghtgs d prdlumtds, qug hd ofgmtgh gb hûmbgd. Gb OLH gxtromrd`dsý`nmd puglg gstor osdmnold o uh morïmtgr.