Hepatitis

 

HEPATITIS

 

Infeksi virus termasuk virus hepatitis

Alkoholism

Keracunan

Malaria Kurang gizi

 

VIRUS 

Organisme terkecil dengan ukuran 20-40 nm

 T  Terdiri erdiri dari Core Core ( inti), Casid (selu!ung) dan "n#eloe (kasul)  $engandung satu %enis asam nukleat 

(R&'&')  *idu dan !erelik !erelikasi asi tergantung ada sel e%amu ( +ost)

 

Penyebab hepatitis 

Virus *eatitis '



Virus *eatitis 



Virus *eatitis 



Virus *eatitis TT



Virus *eatitis C



Virus +eatitis lain



Virus *eatitis 



.en/akit autoimun



Virus *eatitis "



O!at, racun

 

Jenis-jenis Hepatitis Virus VIRUS

NAMA LAIN

PENULARAN

*eatitis ' #irus *eatitis Ineksiosa (*'V)

"nteral

INFEKSI

DISTRIBUSI GEOGRAFIK PREVALENSI

VAKSIN

*an/a akut 'rika 11, Timur teng!er#ariasi, a+, eidemis lokal'da 'merika Selatan, soradis tia -30 t+n 'sia timur

*eatitis  #irus*eatitis #irus*eatitis Serum Serum.arenteral, .arenteral, #ertikal, #er tikal, 'kut dan kronik'rika dan 'sia timur 11 1 10 - 400 %uta % uta engida engi da 'da 'da (*V) se5ual (-306) Se!agian 7anada dan *V kronik 'merika Selatan

*ea titis *eatiti s C #irus*e *eatit atitis is &on ' -.arenteral, .arente ral, #erti # ertikal kal 'kut dan kronik  Timur tenga+ tenga+ 11, sedang380 %ut %uta a eng engid ida a e elu lum m ada ada (*CV) &on  se5ual (0-806) di "roa timur, 'merika *CV kronik selatan, 'rika selatan dan 'sia *eatitis  #irus e ellta #irus (*V)

.aren entter era al 'kut dan kronik9 *V, !a !an/ak di Rus30 ia - :06 engida *V 'da (9*V *V ko-aktor /g (-306) kronik, tergantung dari essential daera+n/a

*eatitis " #irus (*"V)

"nteral

*an/a akut

"idemis di 'sia, 'riker#ariasi, a eidemis lokal elum ada Utara dan $e5ico soradis tia -30 t+n

*eatitis  #irus (*V)

.arenteral

'kut dan kronik

elum %elas

elum %elas

elum ada

 

Hepatitis C: “Sleeping with the Enemy” (musuh dalam selimut)

 

Statistik Global

; 17 !"ta

te#in$e%si ; G&'ba&( )*

Sumber: WHO Fact Sheet No. 164 2000

 

Statistik Regional Indo: 7 juta

Indonesia: 65 % Gen-1

In+'nesia( Ka,asan yan- An-%a Ke!a+iannya Tin--i .+iban+in- E#'pa +an A/e#i%a0 Sumber: WHO Fact Sheet No. 164 2000

 

Vius Hepatitis C    



Small, en#eloed, single-strande single-stranded d R&' #irus .ersistent inection linked ?it+ c+ronic +eatitis, cirr+ cirr+osis, osis, +eatocellular +e +eatoce atocellular llular carcinoma Forld?ide distri!ution = *V carrier re#alence 136 in 'sia> *V resent in !lood, semen, cer#ico#aginal secretions, sali#a, ot+er !od/ Juids>

 

$odes o transmission B&''+b'#ne  Reciients o multile !lood roducts 

In%ecting drug user *emodial/sis atients  *ealt+ care and ot+er ?orkers e5osed to !lood Se"a& t#ans/issi' n t# ans/issi'n 

Tiss"e penet#ati'ns   (ercutaneous) or ermucosal transer 

&eedlestick accidents S+ared raHo!lades  T  Tattoo attoo  'cuuncture  S+ared toot+!rus+es S+ared toot+!rus+es Mate#na&ne'nata& /ate#na&in$ant t#ans/issi'n N' e5i+en6e $'# $e6a& 

'#a& sp#ea+

 

Epi+e/i'&'-y an+ #is% $a6t'#s 2DV Incu!ation eriod = 4-8 ?eeks  "ndemic in $editerr $editerranean anean !asin, 

"uroean arts $iddle o ormer So#iet Union, arts o 'rica, "ast, and 'maHon !asin>  Vir Viremia emia s+ort s+ort li#ed li#ed (acute inection) or rolonged (c+ronic inection)>  *V inections occur solel/ in indi#iduals at risk or * *V V inection (coinections or suerinections)  $odes o transmission

 

Epi+e/i'&'-y an+ #is% $a6t'#s 2?V 2?V Incu!ation eriod =3 to 3:0 da/s (ma%or eak at a!out 0 da/s)  .rolonged .rolonged #iremia and ersistent inection common = ?ide geogra+ic distri!ution  .ersistent inection linked ?it+ c+ronic 

+eatitis, carcinomacirr+osis, +eatocellular  $odes o transmission

 

Epi+e/i'&'-y an+ #is% $a6t'#s 2GV

Incu!ation eriod uncertain  .rolonged .rolonged #iremia and ersistent inection common  *V R&' in 30 K 206 o atients ?it+ 

C+ronic +eatitis  C+ronic +eatitis   C+ronic +eatitis C  Cr/togenic cirr+osis 



$odes o transmission

 

Insidensi 7*S didunia sesuai distri!usi geograAk= kategori

  4 4

Insidensi tinggi 30-20 kasus er 300>000 enduduk  Insidensi sedang  K  kasus er 300>000 enduduk  Insidensi renda+ L kasus er 300>000 

enduduk C ina, 'rika Indonesia, Cina, enggara insidensi insidens i tinggi 'rika Selatan, 'sia T Tenggara Indonesia M 2@,3 kasus300>000 enduduk

 

Umum 'sia, 'rik 'rika a 20 K 40 ta+un ta+un  "roa, 'merika 'merika 1 :0 ta+un ta+un 



$oHam!iNua 2 K 4 ta+un   00 00 kali le!i+ tinggi di!anding 'merika