Hemodynamic Disorders, Thromboembolic Disease and Shock

May 17, 2018 | Author: pjcanero | Category: Coagulation, Platelet, Thrombosis, Embolism, Edema
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Hemodynamic Disorders, Thromboembolic Disease and Shock...

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PATHOLOGY

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Robbins and Cotran: Chapter 4 emodynamic Disorders, hromboembolic Diseases, and hock 1 Guia, Alexa M.

–   2D



Edema

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PATHOLOGY

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Robbins and Cotran: Chapter 4 emodynamic Disorders, hromboembolic Diseases, and hock 2 Guia, Alexa M.

–   2D

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Increased salt retention with obligate assoc. water  o

Causes both increased hydrostatic pressure

PATHOLOGY

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Robbins and Cotran: Chapter 4 emodynamic Disorders, hromboembolic Diseases, and hock 3 Guia, Alexa M.

–   2D

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o

Due to vascular injury, including trauma, atherosclerosis, or inflammatory or neoplastic erosion of the vessel wall. 

PATHOLOGY

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Robbins and Cotran: Chapter 4 emodynamic Disorders, hromboembolic Diseases, and hock 4 Guia, Alexa M.

–   2D

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o

Degrades adenosine diphosphate (ADP) o

PATHOLOGY

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Robbins and Cotran: Chapter 4 emodynamic Disorders, hromboembolic Diseases, and hock 5 Guia, Alexa M.

–   2D

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Concurrent activation of the coagulation cascade generates (stabilizes the platelet plug via two mechanisms) o

PATHOLOGY

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Robbins and Cotran: Chapter 4 emodynamic Disorders, hromboembolic Diseases, and hock 6 Guia, Alexa M.

–   2D

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o

 Activated by binding to heparin-like molecules on endothelial cells (heparin  –   minimize thrombosis) 

PATHOLOGY

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Robbins and Cotran: Chapter 4 emodynamic Disorders, hromboembolic Diseases, and hock 7 Guia, Alexa M.

–   2D

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o

Causes small vessel stasis 

Deformed red cells in

o

PATHOLOGY

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Robbins and Cotran: Chapter 4 emodynamic Disorders, hromboembolic Diseases, and hock 8 Guia, Alexa M.

–   2D

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o

Can develop anywhere in the cardiovascular system o

Size and shape of thrombi depend on the site of origin and the cause o

PATHOLOGY

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Robbins and Cotran: Chapter 4 emodynamic Disorders, hromboembolic Diseases, and hock 9 Guia, Alexa M.

–   2D

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 Altered t-PA production o

  (systemic hypercoagulability) o

PATHOLOGY

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Robbins and Cotran: Chapter 4 emodynamic Disorders, hromboembolic Diseases, and hock 10 Guia, Alexa M.

–   2D

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Fat and associated cells released by marrow or adipose tissue injury may enter the circulation after the rupture of the marrow vascular sinusoids or venules 

PATHOLOGY

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Robbins and Cotran: Chapter 4 emodynamic Disorders, hromboembolic Diseases, and hock 11 Guia, Alexa M.

–   2D

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o

Where tissue density limits the seepage of blood from adjoining capillary beds into the necrotic areas 

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PATHOLOGY

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Robbins and Cotran: Chapter 4 emodynamic Disorders, hromboembolic Diseases, and hock 13 Guia, Alexa M.

–   2D 

Endothelial injury 

  adult respiratory distress syndrome 

Cause the failure of multiple organs (kidneys, liver, lungs, and heart)

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