finals '08

PHARMACOLOGY Finals ‘08 By: MMIKIDSÜ

1. Neuropathic pain a. carbamazepine b. gabapentin c. valproic acid 2. Crosses the BBB when inflamed Aztreonam 3. Resapiratory depression - narcotic 4. Global depression - barbiturate 5. Beat-to-beat variability phenothiazine 6. Hypotonia, hyperthermia – benzodiazepine 7. MOA theophylline 8. MOA terbutaline 9. MOA cromolyn Na 10. MOA phentolamine 11. MOA phenylephrine 12. Streptozotocin – tumor of the pancreas 13. Thiotepa – superficial gall bladder CA 14. Cytarabine – AML 15. Carmustine – brain tumors 16. paradoxical hyperactivity – phenobarbital 17. emergency hypertension – esmolol/ labetalol? 18. MOA nitrates 19. MOA B blockers 20. MOA Ca blockers 21. MOA Nitrats + B blockers or Ca blockers 22. MOA Amphotericin B 23. MOA Fluconazole 24. MOA Nevirapine 25. MOA Acyclovir 26. Dec VLDL = dec LDL - Niacin 27. Not for Staph infection – aminoglycosides/ cephalosporin 28. + evidence of risk but the benefit outweighs the risk – D 29. Pharyngitis – methylpenicillin 30. hypernatremia, dehydration – mannitol? 31. anabolic – glucose to glycogen 32. Enz that release NO to bld vessels – gluta 33. INH – mycolic acid 34. Streptomycin – protein synthesis 35. Rifampicin – DNA dependent 36. Ethambutol – 37. Inc BP and angina – enalapril 38. Ranitidine – H1 39. Omeprazole – with or without food 40. Mg OH2 – fast acting 41. Sucralfate – mucosa _________

42. Theophylline – bronchodilator and anti inflame 43. PGI2 – cervix ripening? 44. PGE2 – 45. TXA2 – platelet aggregation 46. PGE1 - PUD 47. Inc K conductance – sotalol/amiodarone 48. Inhibit Ca – verapamil 49. Induce CYP 450 – rifampicin 50. Hemolysis in G6PD px – dapsone 51. least toxic – fluconazole 52. ½ t – 28 – 35 hrs 53. bioavailability – AUC

54. Paracetamol – NAC 55 Iron – deferoxime 56. OrganoPO4 – pralidoxime 57. Miperidine – naloxone 58. Contraindication of ACE I – pregnancy 59. Addison – hydrocortisone 60. Highest anti inflam – dexamethasone 61. Halothane – hepatotoxicity 62. NO – diffused hypoxia 63. Fentanyl – chest tightness 64. Desflurane - ___________ 65. Every night at bedtime – qhs 66. Praziquantel 67. Chloroquine 68. Pyrantel palmoate 69. Pyrimethamine 70. Remove the parasite in the blood and liver – radical cure 71. Kills gametocyte VOM? – chloroquine 72. Parkinson – diphenhydramine 73. Status epilepticus – diazepam 74. Clomiphene – multiple pregnancy 75. Finasteride – dec libido 76. Contraindicated w/ sildenafil – nitrates 77. Insulin secretagogue – glipizide 78. Only for type 2 DM – metformin 79. Not indication of thiazide – thyrotoxicosis/ DM 80. No cross reactivity – aztreonam 81. Preop hyperthyroid to euthyroid – iodine 82. Thyroid storm – PTU

83. Delayed hypothyroidism – Radio 84. Chlamydia trachomatis – doxycycline 85. Highest conc in the body – highest Vd 86. Rapid excretion in acidic urine – Highest pKa 87. Inhibit dihydropteroate synthase – sulfonamide 88. Advantage of 2nd gen SUR – less AE 89. Not MOA of PTU – thyroglobulin 90.