Farmacologia de La Inflamacion

December 8, 2022 | Author: Anonymous | Category: N/A
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C@VO@NLILB Ï@ HJ I@ GKCI@O@NGÞ  K ON. Elji hj i` Nruz Jkrïqujz

 

Mgstlrg` ^ïktlo`s n`rhgk`ijs hj i` gkc`o`ngþk •







Vuflr N`ilr Xuolr Hlilr



Qjrhgh` hj i` ukngþk Njisl

B`ijkl

Sgrnmlw

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Mgstlrg`

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Hjckgngþk I` gkci`o`ngþk js i` rjspujst` hji sgstjo` gkoukliþbgnl hj uk lrb`kgsol, `i h`ðl n`us`hl ` sus nçiui`s y tjeghls. I` gkci`o`ngþk js, klro`iojktj, uk` rjspujst` rjp`r`hlr`

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Bjkjr`igh`hjs I` gkc`o`ngþk sj gkgng` plr jsouils •









Cïsgnls Puïognls Gkjnnglsls Xr`uoànls @itjr`nglkjs gkoukliþbgn`s

GK^XGXZXL HJ J^XZHGL^ ^ZQJVGLVJ^ JK FGLXJNKLILBÏ@ OJHGN@

 

Bjkjr`igh`hjs

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Bjkjr`igh`hjs

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Bjkjr`igh`hjs •

Ognrlfg`kls •

Q`trlkjs olijnui`rjs `slng`hls ` p`tþbjkls(Q@OQs) Igplpligs`nàrghl

Jxþbjkls Kl Ognrlfg`kls



• • •

Gkhuntlrjs

@içrbjkls Nujrpls jxtr`ðls Nlopujstls tþxgnls Grrgt`ktjs

Hjrgv`hls Njiui`rjs Hjrgv`hls Xgsui`rjs



Jkhþbjkls Hjrgv`hls pi`so` Hjrgv`hls OJN



^jð`ijs jogh`s plr nçiui`s jstrjs`h`s, i`so`h`s l oujrt`s Qrlhuntls hj hjbr`h`ngþk hj i` OJN

GK^XGXZXL HJ J^XZHGL^ ^ZQJVGLVJ^ JK FGLXJNKLILBÏ@ OJHGN@

 

Bjkjr`igh`hjs

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Xgpls hj gk`o`ngþk

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Gk`o`ngþk `buh` Jijojktls njktr`ijs

 @itjr`ngþk jk ji n`igfrj hj ils v`sls s`kbuïkjls (v`slhgi`t`ngþk)

- pjrogtj gknrjojktl hji cuel s`kbuïkjl.  N`ofgls jstruntur`ijs jk i` ognrlv`snui`tur` nlk `uojktl hj i` pjroj`fgigh`h - quj pjrogtj ` i`s prltjïk`s pi`soàn`s pi`soàn`s y nçiui`s `f`khlk`r i` ngrnui`ngþk.  Ogbr`ngþk Ogbr`ngþk,, `nuoui`ngþk y `nv`ngþk hj ijunlngtls - m`ng` y jk ji lnl gkc`o`tlrgl gkc`o`tlrgl

GK^XGXZXL HJ J^XZHGL^ ^ZQJVGLVJ^ JK FGLXJNKLILBÏ@ OJHGN@

 

Bjkjr`igh`hjs

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Bjkjr`igh`hjs

GK^XGXZXL HJ J^XZHGL^ ^ZQJVGLVJ^ JK FGLXJNKLILBÏ@ OJHGN@

 

S`slhgi`t`ngþk

 Qrlhunj n`ofgls jk ji

n`igfrj y cuel v`snui`r.  Hj nlogjkzl n`sg gkojhg`tl iujbl hj i` gkeurg`.  Ojhg`h` plr i` mgst`ogk` y ji KL, jktrj ltrls.

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Ojhg`hlrjs hji rlh`ogjktl y `hmjsgþk ijunlngt`rg`

GN@O-0, oliçnui` hj `hmjsgþk gktjrnjiui`r 0 IC@-0, `ktïbjkl 0 `slng`hl ` i` cukngþk ijunlnïtgn` O`n-0, `ktïbjkl 0 hj ils o`nrþc`bls SN@O-0, oliçnui` hj `hmjsgþk 0 hj i`s nçiui`s v`snui`rjs SI@-8, `ktïbjkl ouy t`rhïl 8 NH>0(QN@O-0), Oliçnui`s hj `hmjsgþk hj nçiui`s jkhltjig`ijs pi`qujt`rg`s

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Oliçnui`s hj `hmjsgþk

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Vlh`ogjktl ijunlngt`rgl Ji rlh`ogjktl js ojhg`hl plr i` `ogig` hj i`s sjijnk`s5 J-sjijnk (jkhltjigl) Q-sjijnk (pi`qujt`s, jkhltjigl) I-sjijnk (ijunlngtls)

I`s sjijnk`s ojhg`k i` prgojr` jt`p` hj i` `hmjsgþk hj ils ijunlngtls `ngigt`khl uk` ukgþk tjkuj `i jkhltjigl

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Vlh`ogjktl ijunlngt`rgl

 

@hmjsgþk5 Jstj prlnjsl vgjkj ojhg`hl plr i` gktjr`nngþk jktrj i`s gktjbrgk`s quj sj jxprjs`k slfrj i`s supjrngjs hj ils ijunlngtls y ils nlrrjsplkhgjktjs igb`khls jk i`s nçiui`s jkhltjig`ijs Ltr`s oliçnui`s hj `hmjsgþk nlogjkz`k su p`rngp`ngþk5 - @ kgvji jkhltjig`i5 GN@O-0, SN@O-0 - @ kgvji ijunlngt`rgl5 gktjbrgk`s (IC@0, O`n-0, SI@-8) GN@O-0, oliçnui` hj `hmjsgþk gktjrnjiui`r 0 SN@O-0, oliçnui` hj `hmjsgþk 0 hj i`s nçiui`s v`snui`rjs IC@-0, `ktïbjkl 0 `slng`hl ` i` cukngþk ijunlnïtgn` O`n-0, `ktïbjkl 0 hj ils o`nrþc`bls SI@-8, `ktïbjkl ouy t`rhïl 8

 

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Jxtr`v`s`ngþk ijunlngt`rg` Xr`ksogbr`ngþk (hg`pçhjsgs) Lnurrj iujbl hj i` `hmjsgþk roj hji ijunlngtl `i jkhltjigl, slfrj tlhl jk vçkui`s vï` QJN@O„0 (NH>0).

^j hjfj slfrjp`s`r i` ojofr`k` f`s`i, p`r` il nu`i ji ijunlngtl uigz` jkzgo`s prltjliïn`s (nli`bjk`s`s).

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Jxtr`v`s`ngþk ijunlngt`rg`

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Pugoglt`xgs Ji ijunlngtl sgbuj uk br`hgjktj quïognl m`ng` ji sgl hj gkeurg`. Jstj br`hgjktj pujhj jst`r h`hl plr5  „ Qrlhuntls Qrlhuntls f`nt f`ntjrg`kls jrg`kls sliufijs (K-lroyi).  „ Nloplkjktjs Nloplkjktjs hji nnlopijojkt lopijojktl l (N:`).  „ Ngtlqugk`s Ngtlqugk`s (GI-=).  „ Ojt`fligtls Ojt`fligtls hji @@ (I (IXF8 XF8 ).

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Vlh`ogjktl, `hmjsgþk y hg`pçhjsgs

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Ojhg`hlrjs quïognls  Ojhg`k ils prlnjsls njiui`rjs y v`snui`rjs hj i` gkc`o`ngþk

`buh` y nrþkgn`.  Hj lrgbjk pi`soànl (prjnurslrjs) l njiui`r (prjlro`hls l

sgktjz`hls hj klvl).  ^j ukjk ` rjnjptlrjs jspjnïnls hj i`s nçiui`s fi`knl.  Qujhjk tjkjr oõipijs uknglkjs. Gkgng`k l o`kjkjk i` rjspujst` gkc`o`tlrg`4 ltrls i` rjk`k.  Nlrt` vgh` ojhg`.

GK^XGXZXL HJ J^XZHGL^ ^ZQJVGLVJ^ JK FGLXJNKLILBÏ@ OJHGN@

 

Ojhg`hlrjs quïognls

GK^XGXZXL HJ J^XZHGL^ ^ZQJVGLVJ^ JK FGLXJNKLILBÏ@ OJHGN@  

GK^XGXZXL HJ J^XZHGL^ ^ZQJVGLVJ^ JK FGLXJNKLILBÏ@ OJHGN@

Vjspujst`

 

• H`ðl njiui`r

Gkci`o`tlrg` GKCI@O@NGÞK

• Ijunlngtls4 igfjr`k jkzgo`s igslsþogn`s • Igfjr`ngþk hj Ànghl @r`qughþkgnl • ^ïktjsgs hj Jgnls`klghjs

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QVL^X@BI@KHG  K@^ • @ntõ`k slfrj5 ^@KBZ ÏKJL^ • S@^L^ ^@KBZÏKJL^ XJVOGK@NGLKJ^ KJVSGL^@^

• NÇIZI@^ GKCI@O@XLVG@^

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• Jstïouil Klngvl • Qjrturf`ngþk hj i` ojofr`k` njiui`r • Clscliïpghls •

Nlrtgnljstjrlghjs

Clscligp`s` @ Ànghl @r`qughþkgnl



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IXF 8

IXN/H8/J8

• C`blngtls

@itjr`ngþk hj i`

(`tr`nngþk/`ntgv`ngþk)

GKCI@O@NGÞK

pjroj`fgigh`h v`snui`r, nlkstrgnngþk frlkqug`i, `uojktl hj i`s sjnrjnglkjs  

FVLKNLJ^Q@^OL, NLKBJ^XGLK, X@QÞK OZNL^L

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L]GBJK@^@

Qrlst`bi`khgk`s

(NL] )

Xrloflx`kls Qrlst`ngnigk`

@itjr`ngþk hj i` pjroj`fgigh`h pjroj`fgigh` h v`snui`r, v`snui`r, nlkstrgnngþk frlkqug`i, `uojktl hj i`s sjnrjnglkjs FVLKNLJ^Q@^OL, NLKBJ^XGLK, X@QÞK OZNL^L

 

Ol hg n`ng GKCI@O@NGÞK

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þk

 

I` ijsgþk hj i` ojofr`k` njiui`r  igfjr` clscligpghls

W nlogjkz` i` sïktjsgs hj Ànghl @r`qughþkgn @r`qughþkgnl l quj prlhun prl hungrà grà prlst` prlst`bi` bi`khg khgk`s k`s Ils @GKJ‗s slk gkmgfghlrjs hj NL]0 y NL] 6

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@K@IBJ^GN L^ hji Lpgl sj utgigz`k p`r` nlrrjbgr ji • Hjrgv`hls hlilr gktjksl. • @GKJ^, sj utgigz`k p`r` ji hlilr olhjr`hl ` ijvj4 nlksjnujkng` hji prlnjsl gk`o`tlrgl.

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@K@IBÇ^GNL^ , @KXGQGVÇXGNL^ W @KXGGKCI@O@XLVGL^ KL J^XJVLGHJL^

@GKJs

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@GK Js

• ^lk uk brupl hj càro`nls hj jstruntur` quïogn` hgcjrjktj quj tgjkjk nlol jcjntl prgo`rgl gkmgfgr i` sïktjsgs hj QVL^X@BI@K QVL^X@BI@KHGK@^, HGK@^, ` tr`vçs hj i` gkmgfgngþk hj i` NGNIL-L]GBJK@^@

• Ij jkzgo` js rjsplks`fij hj i` sïktjsgs hj

prlst`bi`khgk`s, i`s nu`ijs slk ojhg`hlr`s hj cjfrj, hlilr j gk`o`ngþk

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@bjktjs `ktg-gkci`o`tlrgls

• @ktg-gk`o`tlrgls jstjrlghjls l biunlnlrtgnlghjs4 pltjktjs `ktg-gk`o`tlrgls • @k`ibçsgnls `ktgpgrçtgnls, `ktg-gk`o`tlrgls kl jstjrlghjls (@GKJs) l hrlb`s tgpl `spgrgk`. uk brupl fgjk hgcjrjkng`hl hj `k`ibçsgnls • Jxgstj pltjktjs5 lpglghjs nlol i` olrk`s, ojpjrghgk`, cjkt`kgil.

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• Qrlhunjk gkmgfgngþk grrjvjrsgfij hj ngnil-lxgbjkjk`s` pi`qujt`rg` plr ojhgl hj i` `njtgi`ngþk (`spgrgk`)

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QGV@ULILK @^ @ktgpgrgk` l • cjkgifut`zlk`,

Cjk`slk` y @ogklpgrgk`, hgpgrlk`, lxgcjkfut`zlk`, B`o`njtlcjkgifut`zlk`, Qgr`zlklfut`zlk`, Nilcjk`zlk`, ^uxgfuzlk`,

@z`prlp`zlk`. hj i` ngnil-lxgbjk`s`5 `k`ibçsgnls • ^lk gkmgfghlrjs nlopjtgtgvls hj y `ktgpgrçtgnls.

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HJVGS@HL^ HJI Q@V@@OGKLCJKLI

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GKHLI J^

• Gkhlojt`ngk`, Fjkzgh`ogh`, ^uigkh`n, @njojt`ngk`, Qrlbiuojt`ngk`, Qrlbiuojt `ngk`, X`iojt`ngk`.

• ^j ukj j gkmgfj prjcjrjktjojktj ` NL]0

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HJVGS@HL^ HJI ÀNGHL @NÇXGNL >. QGV@KL@NÇXGNL5 Jtlhli`n4 gkmgfghlr hj NL]6

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• ^lk gkmgfghlrjs rjvjrsgfijs y nlopjtgtgvls hj i` ngnillxgbjk`s`.

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HJVGS@HL^ HJI ÀNGHL QVLQGÞKGNL Djtlprlcjkl, lcjkl, K`prlx K`prlxjkl jkl, Gkhlprlcjkl, • Gfuprlcjk1, Djtlpr

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• Nilkgxgk`tl hj Igsgk`

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NL]66 • Kgojsuigh`4 gkmgfgngþk hj NL]

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HJVGS@HL^ HJ I@^ FJK^L]@NGK@^

• Kjclp`o, `k`ibçsgnl ogsnjiàkjl kl lpg`njl hj `nngþk njktr`i

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