Extraccion de Antraquinonas y Cannabinoides

 

NU][GCCHÓL N HMNL]H@HCGCHÓL MN GL][GW^HLILGS X CGLLGKHLIHMNS. H.

IKJN]HPIS

(sçkhb khbg) g) y Nxtrgcchó chól l mn gltrgq gltrgquhl uhlilg ilgss mnb bçt bçtnx nx mn   Gbin vnrg (sç 7. Nxtrgc cgllgkhlihmns mn bgs eijgs mn  Cgllgkhs sgthvg (ogrheuglg).

;. Hmnlth`hcgchól mn gltrgquhlilgs mnb bgtnx mn   Gbin Gbin vnrg (sçkhbg) y mn cgllgkhlihmns mn bgs eijgs mn   Cgl Cgllgk lgkhs hs sgt sgthvg hvg (ogrheuglg) pir  rngcchilns mn cibirgchól y prnchphtgchól.

3.  Glçbhshs nspnctrgb ^P-Phs mn gltrgquhlilgs mnb bgtnx mn   Gbin Gbin vnrg (sçkhbg).

HH.

HL][IM^CCHÓL

Bgs quhlilgs cioprnlmnl ul drupi ouy mhstrhkuhmi nl bg lgturgbnzg y mn nstructurgs rnbgchilgmgs nl bg ogyirïg mn bis cgsis cil phdonltis lgturgbns. Sil oçs cioulns nl vndntgbns gulqun gbdulgs nstructurgs punmnl snr ghsbgmgs mn eildis, bïqunlns, hlsnctis h lsnctis y glhogbns ogrhlis. Qir bi dnlnrgb nl mnpnlmnlchg mnb drgmi mn ciljudgchól prnsnltgl cibirns cioi nb gogrhbbi, riji i cgronbhtg, gulqun tgokhèl gbdulis hltnronmhis. Cuglmi bgs nstructurgs sn prnsnltgl nl `irog mn sgbns i cil cilsthtuchilns ehmrixïbhcgs bis cibirns punmnl snr purpurg gzub i vnrmn. Ns prik prikgk gkbn bn qu qun n su pr prns nsnl nlch chg g nl bi biss irdg irdglh lhso sois is vh vhvi viss mi milm lmn n sn nlcunltrgl, sn mnkg g qun pir su nstructurg mnsnopn÷nl ul pgpnb hopirtgltn nl bis pricnsis mn óxhmi-rnmucchól (ci-nlzhogs), bi cugb sn punmn nxpbhcgr nl nb nquhbhkrhi cioi `irog ixhmgmg y `irog rnmuchmg.

[NM^CCHÓL

IUHMGCHÓL

 

Nl rnbgchól g sus nstructurgs bgs quhlilgs mn irhdnl lgturgb sn punmnl gdru rupg pgrr

nl

cug ugtr tri i

dr dru upi pis: s:

(knl (knlzziq iqu uhl hlil ilgs gs,,

lg`ti g`tiq quh uhl lilg ilgs,

gltrgquhlilgs y `nlgltriquhlilgs)

Knlzii uhli Knlz uhlilg lg   Lg Lg`ti `tiqu quhl hlil ilgg

Gltr Gl trgq gquh uhli lilg lg

@nlgltriquhlilg

Bg gltrgq gltrgquhl uhlilg ilg i 8,71-m 8,71-mhix hixigl igltrg trgcnl cnli i ns ul cio ciopun punsti sti ird irdçl çlhci hci grioçthci, mnrhvgmi mnb gltrgcnli gltrgcnli.. Bg gltrgquhlilg sn nlcunltrg nl `i `iro rog g lgtu lgturg rgbb nl gbd bdu ulg lgss pbg bgl ltg tgss ([uhkgrki [uhkgrki,, Nsp Nsphli hli Cnrvgb Cnrvgb y  y nb dèlnri Çbin dèlnri  Çbin)).Bis

mnrhvgmis

lgturgbns

mn

bg

gltrgquhlilg

sil dbucóshmis cil dbucóshmis cil gcchól bgxgltn y bgxgltn y purdgltn purdgltn suogonltn  suogonltn pitnltn. Bg mridg nstç cilsthtuhmg pir bgs suohmgmns `birhmgs y li `nculmgmgs mnsncgmgs rhcgs nl rnshlg, mn bg pbgltg `nonlhlg mn Cgllgkhs sgthvg B. vgrhnmgm hlmhcg, (Cgllgkgcngn). Bg hl`birnscnlchg mn cibir pgrmi thnln priphnmgmns nstupn`gchnltns qun nxhstnl nl onlir drgmi nl bg vgrhnmgm tnxthb (Cgllgkhs sgthvg vgrhnmgm vubdgrhs). @un uthbhzgmg glthdugonltn nl bg onmhchlg cehlg cioi glgbdèshci y glnstèshci, nltrn itris usis. Qistnrhironltn sn nxpglmhó gb Instn y `un

 

ut uthbhbhz hzgm gmg g nl Nu Nuri ripg pg,, mi milm lmn n sn ut uthbh hbhzó zó ci cioi oi on onmh mhcg cgon onlt lti i pg pgrg rg nb trgtgohnlti mn bg ohdrg÷g y lnurgbdhgs. Gctugbonltn su usi tnrgpèuthci nstç priehkhmi, shnlmi ikjnti mn ul trç`hci hbïchti cilshmnrgkbn. Bis cgllgkhlihmns sil ciopunstis quïohcis quïohcis pnrtnlnchnltns gb drupi mn bis tnrpnli-`nlibns y qun gcthvgl bis rncnptirns cgllgkhlihmns nl cgllgkhlihmns nl nb irdg ir dglh lhso soi i eu euog ogli li.. Sil Sil mn mnrh rhvg vgmi miss mn bg pb pbgl gltg tg mn og ogrh rheu eugl glg g (Cgllgkhs sgthvg). ^li

mn

bis

cgllgkhlihmns

oçs

cilichmis

ns

nb ]EC ]EC (tntrgehmricgllgkhlib),  (tntrgehmricgllgkhlib), hldrnmhnltn pshcigcthvi mn bg ogrheuglg nb cugb cu gb pisnn pisnn ul drg drgl l pitnlc pitnlchgb hgb pgr pgrg g nb trgtgo trgtgohnl hnlti ti mn nl` nl`nro nronmg nmgmns mns lnurimndnlnrgthvgs cioi bg nscbnrishs oúbthpbn, nb ogb mn Gbzenhonr y tgokhèl cioi glthhl`bgogtirhi y glthnoèthci.

HHH.

OG]N[HGBNS: 7. Ounstrg -

Eijgs mn  Gbin Gbin vnrg (sçkhbg)

-

Eijgs mn Cgllgkhs sgthvg (ogrheuglg)

;. Ogtn Ogtnrh rhgb gb mn vh vhmr mrhi hi:: -

Mn usi cioúl nl nb bgkirgtirhi mn @grogcidlishg.

3. Sibv Sibvnl nltn tnss y [ngct [ngcthv hvis is::

 

HP. HP.

-

Gdug mnsthbgmg

-

Ètnr mhntïbhci

-

Ètnr mn Qntróbni

-

Ontglib

-

Ntglib 80º

-

Çchmi sub`úrhci Ehmróxhmi mn simhi

-

Knlcnli

-

Gcntgti mn nthbi

-

Çchmi gcèthci

-

Ehmróxhmi mn Qitgshi

-

Çchmi cbireïmrhci

-

Gcntilg

-

@gst Kbun

-

Goilhgci Himi

Q[IC ICN NMH MHOH OHN NL]I L]I NU NUQ QN[ N[HO HONL NL] ]GB 7. GL][ GL][GW GW^H ^HLI LILG LGS S 7.7.NU][GCCHÓL g. Ikt Iktnlc nlchól hól mnb Ogtnrh Ogtnrhgb gb P Pnd ndntg ntgbb Bgss eijg Bg eijgss mn Gbin Gbin vnrg vnrg sn snrç rçl l rnci rncibn bnct ctgm gmgs gs mn mnbb jg jgrm rmïl ïl kitçlhci Jgrmïl Kitçlhci [isg Nbnlg mn Bis [ïis Ogrtïlnz mn bg @gcubtgm mn @grogchg y Khiquïohcg mn bg ^lhvnrshmgm Lgchilgb mn ]rujhbbi nl cglthmgm nquhvgbnltn g 7 Fd.

k. Bhophn Bhophnzg zg mnb ogtnr ogtnrhgb hgb vndnt vndntgb gb Bgs eijgs rncibnctgmgs sn bgvgrçl cil gdug cirrhnltn y bundi cil gdug mn mnsthbgmg egstg nbhohlgr bis rnshmuis ciltgohlgltns.

c. Snpg Snpgrg rgch chól ól mnb mnb bbçt çtnx nx Cil gyumg mn ul cucehbbi prnvhgonltn mnshl`nctgmi sn egrç ul cirtn bildhtumhlgb mn bg eijg y pricnmnrç g snpgrgr  bgs cirtnzgs hl`nrhir y supnrhir mn bg eijg mnb ouchbgdi y nb bçtnx.

 

m. Nxtrgcchól Qnsgr > d mn bgtnx y vnrtnr nl ul ogtrgz Nrbnlonynr, gdrndgr >1 ob mn ètnr mhntïbhci y siontnr g rn`buji pir  pnrhimi mn 71 ohlutis pgrg nxtrgnr bgs gltrgquhlilgs nl `irog mn gdbhcól prnsnltns nl bg mridg, pgsgmi nb thnopi mn nxtr nxtrgc gcch chól ól tr trgl gls` s`nr nrhr hr g ul no noku kumi mi mn sn snpg pgrg rgch chól ól y mncgltgr nl ulg `hibg bg `gsn ntèrng (H). Nb rnshmui mnb bçtnx sn vnrtnrç nl ul ogtrgz cil >1 ob mn sibuchól mn çchmi sub`úrhci gb >% y sn bbnvgrç g rn`buji pir  pnrhimi mn 71 ohlutis. Sn nl`rïg y sn `hbtrg bgvglmi nb rnshmui cil 71 ob mn gdug mnsthbgmg. Nb `hbtrgmi sn pgsg g ul noku nokumi mi mn snpg snpgrg rgch chól ól y sn rngb rngbhz hzgl gl ; pg pgrt rthc hchi hiln lnss sucnshvgs cil ;1 ob mn ètnr mhntïbhci (HH). Sn rnúlnl bis nxtrgctis ntèrnis (H y HH) y sn cilcnltrgl g ¼ mn su vibuonl hlhchgb. Qistnrhironltn sn trgs`hnrnl g ul nokumi mn snpgrgchól y sn rngbhzg ulg pgrthchól cil 3 vibúonlns sucnshvis mn ;1 ob mn sibuchól mn LgIE gb 71 %. Bgs `gsns gcuisgs sn rnulhrçl y nlrgzgrçl g 711 ob nl ul ogtrgz g`irgmi.

7.;.[NGCCHILNS MN HMNL]H@HCGCHÓL QI[ CIBI[GCHIL g. [ngc [ngcch chól ól mn Kir Kirlt ltrg rgdn dnr  r : Cibóqunsn nl ul tuki mn nlsgyi 1.> d mn mridg, g÷gmhr ;ob mn ètnr mhntïbhci y ogcnrgr pir > ohl, `hbtrgr sikrn gbdimól y trgls`nrhr g itri tuki mn nlsgyi gb nxtrgcti ntèrni iktnlhmi g÷gmhr ulgs ditgs mn sibuchól mn LgIE >%. Bg rngcchól pishthvg sn cgrgctnrhzg pir bg gpgrhchól mn cibir  riji nl bg `gsn gcuisg .

7.3.PGBI[GCHÓL MN GL][GW^HLILGS. Bg sibuchól gcuisg iktnlhmg nl nb pricnsi mn nxtrgcchól sn bnn nl nb `iticibirïontri y sn ciopgrg cil ulg sibuchól pgtról mn noimh oimhl lg i gb gbi ihl hlgg gb 1.7 .7% % nl Sibuc buchól hól mn LgIE gIE 1.7 1.7L .

 

 Gpbïqunsn bgs rndbgs priphgs mn bg cibirhontrïg pgrg nstgkbncnr nb pircnltgjn mn bg ounstrg nl nstumhi.

NJNOQBI: Sh:  

Gks. Sib. Qgtról

-------------------- 7.;1

 

Gks. Sib. Qrikbnog -------------------- 1.;=

Nltilcns:   1.7 d mn gbiïlg ------------------ 7.;1 Gks.  

U -------------------- 1.;= Gks

 

U ? 1.1; d gltrgquhlilgs

Nxprnsgmi nl pircnltgjn: 7. 7.; ; d gl gltr trgq gquh uhli lilg lgss (711 (711)/ )/>d >d ? % ;. CGLLGKHLIHMNS

;.7.NU][GCCHÓL 7 d mn ounstrg sncg y pubvnrhzgmg mn eijgs mn Cgllgkhs sgthvg  sn cgbhnltg nl kg÷i mn gdug cil 71 ob mn ètnr mhntïbhci pir 7>-31 ohlutis, bundi sn `hbtrg sikrn gbdimól y nb nxtrgcti sn dugrmg nl `rgsci çokgr egstg su pistnrhir uthbhzgchól.

;.;.HMNL]H@HCGCHIL g. Hmnlth Hmnlth`hc `hcgch gchól ól Cugbht Cugbhtgth gthvg vg Mnb nx nxtrg trgcti cti ntè ntèrni rni prn prnpgr pgrgmi gmi  onmhr ; ob nl ul tuki mn nlsgyi, cilcnltrgr, gmohlhstrgr nb rngcthvi mn Muqunlihs, y gdrndgr 71 ob mn ECb cc.

 

Bg rngcchól ns pishthvg cuglmi sn iksnrvg bg `irogchól mn ul glhbhbbi gl bi gz gzub ub vh vhib ibnt ntg g nl bg hl hltn tnr` r`gs gsn n qu qun n sn vg mh mh`u `ulm lmhn hnlm lmi i bnltgonltn.

k. Hmnlth`hcg Hmnlth`hcgchól chól p pir ir Criogti Criogtidrg`ï drg`ïgg mn Cgpg Cgpg @ @hlg hlg Mnbb nx Mn nxtr trgc gcti ti ik iktn tnlh lhmi mi ti tiog ogrr ul ulg g gb gbïc ïcui uitg tg y rngb rngbhz hzgr gr bg hmnlth`hcgchól pir CCM. - @gsn nstg nstgchil chilgrhg: grhg:  Sïbh Sïbhcg cg dn dnbb 01 01@ @ ;> ;>= = On Onrc rcff =c =co o mn glcei pir 71 co mn bgrdi. -

@gsn nstgchilgrhg: Cbiri`iroi: Gcntilg 51: ;1 v/v.

-

[nvnbgmirns: i

[ngcthvi @gst Kbun K

i

Buz ^P ;>= y 300 lo

i

Pgpirns mn yimi.

i

-

 Goilhgci.

Qricnmhohnlti: i Sn ogrcgrg cil bçphz mn cgrkól bg bïlng mn hlhchi y `hlgb g 7 co mn bis kirmns supnrhir n hl hl``nrhir mn bg criogtipbgcg y cil ul ohcricgphbgr snokrgr bg ounstrg nl bg bïlng hl`nrhir. i

[ngbhzgr nb cirrhmi nl ulg cçogrg prnvhgonltn sgturgmg cil nb shstnog nbuynltn pir 31 ohl, egstg gbcglzgr bg bïlng ogrcgmg nl nl bg pgrtn supnrhir supnrhir mn bg criogtipbgcg.

i

Sn sncg nl nstu`g y sn rngbhzg nb rnvnbgmi cil sibuchól rnvnbgmirg pgrg cglgkhlihmns @gst Kbun K.

i

Iksnrvgr nl bg bçopgrg ^P.

i

Cgbcubgr nb [`.

 

HL@I[ON MN Q[ÇC]HCG L± 71 H.

Q[ Q[IC ICNM NMHO HOHN HNL] L]IS IS IQ IQN[ N[G] G]HP HPIS IS

HH. [NS^B]GMIS

 

HH HHH. H. MHSC MHSC^S ^SHI HIL L

HP. CILCB^SHIL CILCB^SHILNS NS

 

P. [N@N[NLCH [N@N[NLCHGS GS KHKBHID[G KHKBHID[G@HCGS @HCGS