Drug Study

DRUG NAME

Generic Name: olanzapine

DOSAGE & ROUTE OF THE DRUG

Dosage: 10mg

Zyprexa

Route:

Classification:

Oral

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 Antipsychotic Dopaminergic blocker 

Mechanism of action

INDI IN DICA CATI TION ON

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not fully understood; understood;

Treatment of  schizophrenia

CONT CO NTRA RAIN INDI DICA CA TION

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blocks dopamine

Brand Name:

•

MECHANISM OF ACTION OF THE DRUG

receptors in the

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brain, depresses the RAS; blocks serotonin receptor 

Frequency: HS

sites; anticholinergic, anticholinergic, antihistaminic antihistaminic (H1), and alpha-adrenergic

Timing:

blocking activity may

7pm

contribute to some of 

Treatment of  acute mixed or  manic episodes associated with bipolar 1 disorder and maintenance of  bipolar 1 disorder as monotherapy, or combined with lithium or  valproate

its therapeutic (and adverse) actions; produces fewer extrapyramidal extrapyramidal effects than mostantipsychotics.

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Treatment of  agitation associated with schizophrenia and bipolar 1 mania (injection)

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Contraindicated Contraindicated with allergy to olanzapine, myelo proliferative disorder  s, severe CNS depression, comatose states, lactation. Use cautiously in elderly or debilitated patients, or with CV or cerebrovascular  cerebrovascular  disease, dehydration, dehydration, seizure disorders,  Alzheimer’s disease, disease, prostate enlargement, narrow-angle glaucoma, glaucoma, history of  paralytic ileus or  breast cancer, pregnancy; phenylketonuria phenylketonuria (if  using orally disintegrating tablets, contain phenylalanine).

ADVERSE REACTION / SIDE EFFECTS

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CNS: Somnolence, dizziness, nervousness, headache, aka thisia, personality disorders, tardi ve dyskinesia, neuroleptic malignant syndrome CV: Orthostatic  hypotension, peripheral edema, tachycardia GI: Constipation, abdominal pain Respiratory: Cough, pharyn gitis Other: Fever, development of diabetes mellitus

NURSING RESPONSIBILITI ES

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 Assess for  history of  allergy to olanzapine. Monitor for  the many possible drug interaction before beginning therapy. Encourage patient to void before taking the drug to help decrease anti cholinergic eff  ects of urinary retention. Take this drug exactly as prescribed; do not change dose without consulting your health care provider.

DRUG NAME DRUG NAME Generic Name: Carbamazepine Generic Name: Brand Name: Diazepam Tegretol, Tegretol XR , Equetro, Brand Name: Carbatrol

DOSAGE & ROUTE OF THE DOSAGE DRUG & ROUTE OF THE DRUG

Dosage:

200mg Dosage: 10mg Route:

Oral Route:  Antenex‡,ApoFrequency: Diazepam†,Diastat P.O ,Diazemuls‡,Diaze Classification: pamIntensol,Duce Timing: ne‡,NovoFrequency:  Anticonvulstant Dipam†,PMSDiazepam†,Valium 8 pm TID ,Vivol† Classification:  Anxiolytic

Timing:

MECHANISM OF ACTION OF THE MECHANISM DRUG OF ACTION OF THE DRUG

INDICATIO N INDICATION

• Reduces anxiety, • Decreases synaptic transmission in the CNS irritability, elation •Anxiety by affecting sodium • Impulse control  A benzodiazepine channels in neurons that probably •Acute alcohol behaviour. •potentiates Preventionthe of seizureswithdrawal effects of GABA, Depresses the CNS, •Before endoscopic and suppresses the procedures spread of seizure activity •Muscle spasm •Preoperative sedation •Cardio version •Adjunct treatment For seizure disorders. •Status epilepticus, severe recurrent seizures. •Patients on stable regimens of  antiepileptic drugs who need diazepam intermittently to control bouts of  increased seizure activity.

ADVERSE

CONTRAINDICA REACTION / ADVERSE SIDE EFFECTS TION CONTRAINDICA REACTION / SIDE EFFECTS TION •CNS: headache,

• Hypersensitivity • Kidney disease ••Contraindicated Cardiovascular disease hypersensitive •inpatients Seizure disorder, to drug or soy protein; in myasthenia gravis patients experiencing • Dehydration shock, coma, or acute • Hypothyroidism alcohol intoxication(parenteral form); inpregnant women, especially in first trimester; and in children younger than age 6 months (oral form).

•Dias tat rectal gel is contraindicated inpatients with acute angle-closure glaucoma. •Use cautiously inpatients with liver or renal impairment, depression, or chronicopen-angle glaucoma. Use cautiously in elderly and debilitated patients.

NURSING RESPONSIBILITI NURSING ES RESPONSIBILITI ES

• Administer  medication with food •CNS: drowsiness, •Assess for history restlessness, to minimize gastric of  dysarthria, slurred allergy to Tablets diazepam irritation. memory loss, •CV: hypotension, may be crushed if  CV collapse, seizures, slurred •Use of has this difficulty drug patient bradycardia. may lead to abuse swallowing. Do not speech, muscle •EENT: diplopia, and addiction. crush or chew Don’t blurred vision, withdraw drug weakness, lack of  extended-release nystagmus. abruptly after longtablets. coordination, •GI: nausea, term use; patient withdrawal • Instruct to constipation, diarrhea symptoms lethargy, stupor  may take carbamazepine with rectal form. occur. around the clock, •EENT: blurred •Hematologic: exactly as directed. neutropenia. vision, tinnitus •Monitor If a doseelderly is missed, •Hepatic: jaundice. patients for  as take as soon • GI: anorexia, •Respiratory: dizziness, ataxia, possible but not just respiratory and mental nausea, vomiting, before next status dose; do depression, apnea. changes. Patient’s not double doses. abdominal cramps or  •Skin: rash. are at an increased Medication should •Other: altered libido, pain, diarrhea, dry risk for falls. be gradually physical discontinued to mouth, extreme or psychological prevent seizures. dependence, pain, thirst, metallic taste, • May cause phlebitis at injection dizziness or  weight gain site. drowsiness. • Skin: rash, pruritus, • Instruct patients that fever, sore alopecia, sweating, throat, mouth ulcers, dryness or thinning easy bruising, petechiae, unusual of hair  bleeding, abdominal pain, chills, rash, pale stools, dark urine or jaundice should be reported. tremors, confusion,

DRUG NAME Generic Name:

DOSAGE & ROUTE OF THE DRUG

MECHANISM OF ACTION OF THE DRUG

INDICATION

CONTRAINDICA TION

INDICATION

CONTRAINDICA

ADVERSE REACTION / SIDE EFFECTS

NURSING RESPONSIBILITI ES

ADVERSE

NURSING

Dosage:

Levomepromazine

Brand Name: Route:

Classification: Frequency:

Timing:

DRUG

DOSAGE &

MECHANISM OF