Dosis Obat

 

DOSIS OBAT

Hidajah Rachmawati,S..Si,Apt,SpFRS

 

PENGERTIAN UMUM MENGENAI DOSIS PENGERTIAN Dosis obat: jumah !"at #$ di"%&i'a( 'pd p) dm *atua( "%&at +$&am, mii$&am, mi'&!$&am atau *atua( i*i +miiit%&, it%& atau u(it-u(it ai((#a +U(it I(t%&(a*i!(a Kecuali lain Dosis Obat : *%jumahdinyatakan !"at #$ m%m"%&i'a( %%' t%&ap%uti' pd p) dw*, di*%"ut ju$a : d!*i* a/im atau d!*i* m%dici(ai* atau d!*i* t%&ap%uti' !"at dm d mpd '%adaa '%adaa( '%adaa( Dosis Dosi s Toxica: Toxic oxica: a: d!*i* dpt m%(#%"a"'a( '%&acu(a( p) ( "ia*a #$ %adaa( Dosis Letalis: d!*i* !"at dm d m ' '%adaa( '%adaa ( "ia*a #$ dpt m%(#%"a"'a( '%matia( pd p).+0D 12 da( 0D 322

 

FA4TOR-FA4TOR 5G MEMPENGARUHI DOSIS OBAT Faktor Obat:  Siat 6*i'a  +da#a a&ut !"at daam ai&7%ma','&i*ta7am!&, d*"8*iat 'imiawi +a*am, "a*a, $a&am, %*t%&, $a&am '!mp%'*, pH,p pH,p4a8T 4a8T!'*i*i !'*i*ita* ta* +d!*i* ++d!*i* d!*i* !"at pH,p4a8T!'*i*ita* "%&"a(di($ t%&"ai' d$( t!'*i*ita*(#a Cara Pemberian Obat Kepada Px:O&a dimi(um8pa&%(t%&a+*u"'uta(, uta(, +dima'a( atau dimi(um8pa&%(t%&a+*u"' i(t&amu*cua&, i(t&a9%(a d*"8 R%'ta,9a$i(a,u&%t&a 0!'a,t!pica,t&a(*d%&ma 0ai(-ai(: impa(ta*i, *u"i($ua, i(t&a"u'a,d*".

 

0a(juta( FA4TOR-FA4TOR

5G MEMPENGARUHI DOSIS OBAT Faktor Penderita/Karekteristik Penderita:

     

3. . ;.   =.   1.

Umu&: Umu&:  (%!(atu*, (%!(atu*,  "a#i, a(a', d%wa*a, $%&iat&i'. B%&at "ada(   $ C ,>@2 $ C ;,; $ C 3>?2 m$ C ?@1 m$ C

m$ m$ m$ m$ $ $

1=,1 m$C 12>1 m$ C 3,1 m$ C 122 mc$C

$ $ mc$ m$

 

LATIHAN 3, $C 2,1> $ C ,>@2 $ C ;,; $ C 3>?2 m$ C ?@1 m$ C

m$ m$ m$ m$ $ $

1=,1 m$C 12>1 m$ C 3,1 m$ C 122 mc$C

$ $ mc$ m$

 

Sediaan cair  Satua( "%&at "aha( a'ti : daam $&am atau daam m$ Satua( 9!um% : m +miiit%& atau 0 +it%& !(t!h : Am!)ic Am!)icii( ii( 31 m$ 7 1 m +!&a Am!)icii( + !&a Baui(!& TM7ED ; m$7m t%t%* mata. .F%(ic! %(ic! m%($a(du($ h!&h%(ic! 3,* .F 1 m +3 C 3 $&am daam 322 m campu&a( a&uta(

 

Latian 3.

.

;.

Apa a&ti(#a G%(tami*i( *uat 2,; *a%p mata ,tu"%C;$ Apa a&ti(#a 4!&am%(ic! 2,18  TM7ED 31 m 0a&uta( "%tadi(% 2,21

 

Peritun!an Pen!am"i#an Sediaan 

Padat TM 3 m$, daam p%&*%diaa( #a($ ada ta"%t TM m%($a(du($ = m$, "%&apa ta"%t TM #a($ diam"i 







Bia di"uat pu9%&%* N!. II, "%&apa TM ta" #a($ diam"i Di$!)i( ta"%t 2,1 m$ , "ia d!'t%& Di$!)i( m%($h%(da'i 31 mc$ "%&apa ta"%t #a($ di"%&i'a( '% pa*i%( u(tu' *%'ai mi(um Fu&!*%mid% ta" =2 m$,d!'t%& m%($h%(da'i 2 m$ , "%&apa ta"%t #a($ di"%&i'a( '% pa*i%( u(tu' *%'ai mi(um

 

Peritun!an Pen!am"i#an Sediaan 

cair  Am!)*a( !&t% 12 m$71 Am!)*a( m$ 71 m, u(tu' a(a' umu& = tahu( d!*i* #a($



di' di'%h%(da'i %h%(da'i d!'t%& 2,31 $, "%&apa m *#& am!)*a( ha&u* diam"i P&imp%&a( d&!p* d&!p* 2,3 m$7 t%t%* t%t%* , d!*i* a(a' 2,1 m$7'$ "" daam d!*i* "a$i.Bia "" a(a' 32 '$, "%&apa d!*i* #$ di"utuh'a(

 

Peritun!an Pen!am"i#an Sediaan 

inje$si D!'t%& m%($i(*t&u'*i'a( u(tu' m%($i(j%'*i pa*i%( P%thidi( ?1 m$,



#a($ t%&*%dia P P%thidi( %thidi( 322 m$7 m . B%&apa m P%thidi( i(j%'*i diam"i S%t&ia)!( 3$79ia  p%a&ut aua p&! i(j%'*i 32 u(tu' m, "%&apa h&* diam"i "ia d!*i* a(a' m 12 #$ m$7'$7"" 7ha&i

+*%'ai *%ha&i,BB a(a' AC31 '$

 

Kece%atan In&us P%m"%&ia( !"at *%ca&a i(t&a9%(a dihitu($ "%&da*a&' "%&da*a&'a( a( jumah t%t%* p%& miiit%& a&uta(. 4a&%(a #a($ i(*t&u'*i di"%&i'a( "%&upa 9!um% ha&u* di"%&i'a( daam wa'tu t%&t%(tu +mi*a(#a 122 m daam = jam,ma'a dip%&u'a( '%mampua( u(tu' u(tu ' m%($hitu($ '!(9%&*i da&i t%t%* p%& m%(it '% miiit%& p%& m%(it da( *%"ai'(#a

 

Kece%atan In&us B%&apa '%c%pata( ai&a( dip%&u'a( u(tu' m%ma*u''a( a( 122 m d%'t& d%'t&!*a !*a 1 daam ai& m%ma*u'' *%ama @ jam 0a&uta( itu m%m"%&i 31 t%t%*7 m :