Crohn's Disease

 

9. Crohn's Disease Tharina Lawei

 

Crohn's Cr ohn's Disease Disease •

Ileitis terminal / regional (55% pasien)

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Salah satu jenis Inflammatory Bowel Disease

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Karakteristik : diskontuinitas ulserasi transmural, fistulisasi, & pembentukan abses yang spontan. Histologi : granuloma non-kaseosa, kumpulan histiosit epiteloid, & “giant cells” Resiko tinggi untuk kejadian adenokarsinoma

 

Crohn's Cr ohn's Disease Disease

 

Crohn's Cr ohn's Disease Disease

Pola Obstruksi Proses Inflamasi

Fibrostenosis Pola Fistula Penetrasi

 

Crohn's Cr ohn's Disease Disease Tanda & Gejala

Ileokolitis : nyeri kolik kuadran kanan  bawah rekuren, diare, anorexia Yeyunoileitis : malabsorpsi akibat

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kehilangan absorpsi permukaan digestif dan Colitis dan penyakit perianal : demam, malaise, diare, nyeri perut, hematokezia

 

Crohn's Cr ohn's Disease Disease Inflammed edematous villous pattern

Cobblestone's appearance

Strictures, fistulation

EARLY

ADVANCED

COMPLICATED

Ulceration became linear w/ typical transmuralaccompanied by mural thickening

Abscess formation, and rarely tumor.

Early ulceration -> aphtoid (small, shallow, circular,, & discrete circular ulcers sorrounded by halo

 

Crohn's Cr ohn's Disease Disease Tanda spesifik : •

“skip lesion” → area yang sehat & area yang sakit tampak selang seling “cobblestoning” → area ulserasi mukosa yang dipisahkan area mukosa yang normal.

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Crohn's Cr ohn's Disease Disease

 

Crohn's Cr ohn's Disease Disease

COMB SIGN : Distensi pembuluh darah yang dipisahkan  proliferasi lemak fibrosis mesenterium, yang memberikan gambaran “comb”,

TARGET SIGN SIG N : Cincin hiperdens : mukosa dan muskulus propria usus halus yang hiperemis.

disertai “fat stranding”.

Cincin hipodens : edema Pola penyangatan tersebutsubmukosa membentuk gambaran “target sign”.

 

Sumber Pustaka •

Gastrointestinal Gastroin testinal The Requisites

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Textbook of Radiology and Imaging Sutton

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Internal Medicine Harrison Imaging Anatomy Chest, Abdomen and Pelvis

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Dynamic Radiology of the Abdomen Meyer

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