Craniotomy From Wikipedia, the free encyclopedia
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A craniotomy is a surgical operation in which a bone flap is temporarily removed from the skull to access the brain. Craniotomies are often critical operations, performed on patients who are suffering from brain lesions or traumatic brain injury (TBI), and can also allow doctors to surgically implant deep brain stimulators for the treatment of Parkinson's disease, epilepsy, and cerebellar tremor. The procedure is also widely used in neuroscience for extracellular recording, brain imaging, and for neurological manipulations such as electrical stimulation and chemical titration. The procedures are used for accessing brain tissue that must be removed, as well. Craniotomy is distinguished from craniectomy (in which the skull flap is not immediately replaced, allowing the brain to swell, thus reducing intracranial pressure) and from trepanation, the creation of a burr hole through the cranium in to the dura mater. Contents [hide]
Diagram of the elements of a craniotomy.
Human craniotomy is usually performed under general anesthesia but can be also done with the patient awake using a local anaesthetic; the procedure, typically, does not involve significant discomfort for the patient. In general, a craniotomy will be preceded by an MRI scan which provides an image of the brain that the surgeon uses to plan the precise location for bone removal and the appropriate angle of access to the relevant brain areas. The amount of skull that needs to be removed depends on the type of surgery being performed. The bone flap is then replaced using titanium plates and screws or another form of fixation (wire, suture, etc.).
Complications Bacterial meningitis or Viral meningitis occurs in about 0.8 to 1.5% of individuals undergoing craniotomy. Postcraniotomy pain is frequent and moderate to severe in nature. This pain has been controlled through the use of: scalp infiltrations, nerve scalp blocks, parecoxib, andmorphine, morphine being the most effective in providing analgesia. According to the Journal of Neurosurgery, Infections in patients undergoing craniotomy: risk factors associated with post-craniotomy meningitis, their clinical studies indicated that, “…the risk for meningitis was independently associated with perioperative steroid use and ventricular drainage.” Within the 334 procedures that they had conducted from males and females, their results concluded that traumatic brain injuries were the predominant causes of bacterial meningitis. At least 40% of patients became susceptible to at least 1 infection, creating more interconnected risk factors along the way. From the Infectious Diseases Clinic Erasme Hospital, there had been reports of infections initially beginning from either the time of surgery, skin intrusion, hematongenous seeding, or retrograde infections. Cerebrospinal fluid shunt (CSF) associates with the risk of meningitis due to the following factors: pre-shunt associated infections, post-operative CSF leakage, lack of experience from the neurosurgeon, premature birth/young age, advanced age, shunt revisions for dysfunction, and neuroendoscopes.
The way shunts are operated on each patient relies heavily on the cleanliness of the site. Once bacteria penetrates the area of a CSF, the procedure becomes more complicated. The skin is especially necessary to address because it is an external organ. Scratching the incision site can easily create an infection due to no barrier between the open air and wound. Aside from scratching, decubitus ulcer and tissues near the shunt site are also leading pathways for infection susceptibility. 
It is also common to give patients seven days of anti-seizure medications post operatively. Traditionally this has been phenytoin, but now is increasingly levetiracetam as it has a lower risk of drug-drug interactions. 
Jump up^ van de Beek D, Drake JM, Tunkel AR (January 2010). "Nosocomial Bacterial Meningitis".New England Journal of Medicine 362 (2): 146– 154. doi:10.1056/NEJMra0804573.PMID 20071704.
Jump up^ Hansen, Morten S; Brennum, Jannick; Moltke, Finn B.; Dahl, Jørgen B. (December 2011). "Pain treatment after craniotomy: where is the (procedure-specific) evidence? A qualitative systematic review". European Journal of Anaesthesiology 28 (12): 821– 829.doi:10.1097/EJA.0b013e32834a0255.
Jump up^ Szaflarski, J. P; K. S Sangha; C. J Lindsell; L. A Shutter (2010). "Prospective, randomized, single-blinded comparative trial of intravenous levetiracetam versus phenytoin for seizure prophylaxis". Neurocritical care 12 (2): 165–172. doi:10.1007/s12028009-9304-y.
Jump up^ Temkin, N. R; S. S Dikmen; A. J Wilensky; J. Keihm; S. Chabal; H. R Winn (1990). "A randomized, double-blind study of phenytoin for the prevention of post-traumatic seizures".New England Journal of Medicine 323 (8): 497– 502.doi:10.1056/nejm199008233230801.
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Surgery, Nervous system: neurosurgical and other procedures (ICD-9-CM V3 01–0
Decompressive craniectomy Cranioplasty
Thalamotomy thalamus and globus pallidus:
Thalamic stimulator Pallidotomy
Ventriculostomy ventricular system:
Suboccipital puncture Intracranial pressure monitoring
Bilateral cingulotomy Hemispherectomy Anterior temporal lobectomy
Spinal cord and roots Spinal cord and spinal canal
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Computed tomography of the head Cerebral angiography Pneumoencephalography Medical imaging
Echoencephalography/Transcranial Doppler Magnetic resonance imaging of the brain Brain PET Myelography
Lumbar puncture Polysomnography
Glasgow Coma Scale CPRs
Mini–mental state examination National Institutes of Health Stroke Scale CHADS2 score
Cranial and peripheral nerves
Nerve block Vagotomy
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Index of the central nervous system
Anatomy meninges cortex association fibers commissural fibers lateral ventricles basal ganglia diencephalon mesencephalon Description
pons cerebellum medulla spinal cord tracts Physiology neutrotransmission enzymes intermediates Development
Addiction Cerebral palsy Meningitis Demyelinating diseases Seizures and epilepsy Headache Stroke Sleep Congenital Disease
Injury Neoplasms and cancer Other paralytic syndromes ALS Symptoms and signs head and neck eponymous lesions Tests CSF
Procedures Drugs general anesthetics analgesics dependence Treatment
epilepsy cholinergics migraine Parkinson's vertigo other
Index of the peripheral nervous system
Anatomy Nerves cranial trigeminal cervical brachial lumbosacral plexus somatosensory spinal
autonomic Physiology reflexes proteins neurotransmitters transporters Development neurotrophins
Autonomic Congenital Injury Disease
Neoplasms and cancer Other Symptoms and signs eponymous
Procedures Local anesthetics
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