Collection of Questions From Previous HAAD Exams (1) (1) (1)

Collection of questions from previous HAAD exams 1- Thrush caused by - Amoxicillin 2- Oral Salbutamol overdose cause all except? - Constipation 3- The Advice which you must give to patient takes theophylline? - Not to be chewed or crushed in mouth and don’t drink alcohol 4- Hypercapnia is treated by? - Doxapram 5- Fenoldopam used for hypertensive crisis act as - Dopamine Agonist 6- Which of the following not used for angina? - Losartan 7- For sumatriptan which of the following is true? - You can take another tablet after 2 hrs if the attack not relieved 8- Advice for Ventolin diskus all except: - Shake before use 9- Insulin lispro different from human insulin in? - Short onest of action and Short duration of action 10- Methylphenidate is dispensed as - Narcotic drugs 11- For 24 hrs pharmacy need at least - 3 pharmacists and no limit of assistant 12- Benzyl alcohol is used as - Preservatives 13- Have symptoms before lesion or rash appearance? - Cold sore 14- Saline flush is used for - Flush vein between 2 drugs 15- Which of the following used after food - Prednisolone 16- The following combination interact between ( Amiloride + hydrochlorothiazide )

-

ACE-I

17- Aspartame is contraindicated in - Phenylketonuria 18- Mono Nuclease disease is mostly affect - Adult and caused by Epstein–Barr virus 19- Which vaccine is not live attenuated vaccine - Diphtheria 20- High volume of distribution mean - High bound to tissue 21- Oligosaccharides example - Sucrose 22- Gluten is contraindicated in patient with: - Coeliac disease 23- Hyper calcemia is caused by: - Hyperparathyroidism 24- Cold Cream is: - W/O 25- Capsule used in treatment of Influenza: - Oseltamivir 26- Baclofen is classified as: - Skeletal muscle relaxant 27- Corn is due to - High Pressure on foot 28- Post menopausal Hot flush caused by - Decrease of estrogen 29- Which one of the following not cause myalgia ( pain in muscle ) - Cholestyramine 30- Pore size of cold sterilization: - .2 micrometer 31- Which type has improper use of the drugs? - Elder due to polypharmacy 32- Reproducibility is Measurement of - Precise 33- Treatment of mild episodic Asthma:

-

Salbutamol ( B2 Agonist )

34- Patient take Clarithromycin and celecoxib suffer from abdominal pain, cramps, and Diarrhea this is due to: - Antibiotic associated colitis 35- The advice the pharmacist shouldn’t gave to patient regarding Fluoxetine - Need 2-4 weeks to improvement 36- TCA can cause all of this side effect except: - Shortening of the breath 37- All of this test done before taking Isotretinoin except - Blood sugar test 38- All of the following advice given about Isotretinoin except - The acne is worsen and be better again 39- All of this is treatment of Tinea pedis except - Nystatin 40- For decrease frequency of severe Asthma - Na Cromoglycate or dexamethazone 41- Treatment of Prostatitis is - Ciprofloxacin 42- Albumin is bind to - Weak Acid 43- Head lice preparations should use every - 7 – 10 days 44- All are used for otitis Externa except - Docusate-Na 45- Prostate Hyperplasia is due to - Enlargement of prostate and pressure in urethra 46- Ephedrine is contraindicated with patient use - MAO-I 47- Which of the following not used in cough - Vitamin C 48- Lady 28 weeks of pregnancy and suffer from U.T.I which can take safely - Co-Amoxiclav 49- Cancer Patient Receive 20mg / 4 Hrs syrup and want to shift to tablet Morphine what is the best starting dose

-

60 mg B.D

50- For tolerance of Nitrate Make space(free time) from 8-12 Hrs reduce tolerance 51- Minimum temperature for regulator is - 2C 52- If patient take 500 orally and want to shift on I.V dose will be - 500 mg for amoxicillin only 53- For patient on Nasal Feeding what you can make to Aspiration Pneumonia: - raise the bed back .not give prophylaxis antibiotics 54- Which of the following didn’t affect sedimentation rate? - Ionization 55- Side effect of xylometazoline is: - Tachycardia 56- Which gland affect on Calcium: - Parathyroid gland 57- Elidel Cream (Picrolimus) is - CD B (Control Drug B ) 58- Succinylcholine is hydrolyzed by - Esterase 59- Antidote for morphine is - Naloxone 60- The advice for lugol's solution - Staining 61- Elimination rate of high polar compound like mannitol depend on - excretion rate 62- Why is older suffer from more side effect: - They take more than one medicine 63- Patient treated from asthma and he is worsed. He used Corticosteroid + Cromoglycate which of the following can added - Salmetrol 64- Antidote for benzodiazepine is: - Flumazenil 65- Which of the following preparation required Laminar Flow - Doxurobicin

66- Which of the following the main mechanism is enzyme inhibitor - Cimetidine 67- Which Vaccine can Given to elder - Influenza A 68- Alprazolam dispensed as - CD A 69- Prodrug alter all of this characters except - Potency 70- Which of the following not reach systemic CNS - Ipratropium 71- Patient with meningitis and take sample from CSF and show negative Bacteria it may be - H.Influenza 72- Old patient with G6PD and have urinary tract infection which is the safe Antibiotic u can give - Cefuroxime 73- CCL4 is - Carbon tetra chloride ( Macrophage inflammatory protein ) 74- Which is have enantiomer - Escitalopram 75- Lomotil is combination of Atropine + ……………? - Diphenoxylate 76- Opioid Agonist is - Tramal 77- Acute treatment for migraine - Sumatriptan 78- Which medicine cause Constipation - Verapamil also Tramadol and Aluminium 79- Opioid Antagonist is - Naloxone 80- What about β blocker is wrong - Can be used with Asthma patient 81- Maximum daily dose of Paracetamol is

-

4 gm

82- β blocker work on α and β is - Labetelol and Carvidelol 83- Which of the following ↓ frequency of acute Asthmatic Attack? - Fluticasone 84- Which medicine used in treatment of Candida albicans - Fluconazole 85- Leukotriene receptor Antagonist is - Montelukast, Zafirlukast, Zileuton 86- Which one should be adjusted dose in renal Impairment - Digoxin 87- Caution should be taken when using Diuretics - Digoxin as ↑ toxicity by hypokalemia 88- Verapamil contraindicated in - Congestive heart Failure 89- Which one used in treatment of U.T.I and cause Nephrotoxicity - Amphotericin B and nitrofurantoin 90- Patient which takes Etidronate should be advised by - Take it with plenty of water and 30 minute before any food and stand for at least 30 minute or sit position 91- Which one cause extrapyramidal side effect - Metoclopramide 92- Mechanism of action of statin - Reduction of N-Acetyl HMG-Co reductase enzyme 93- General Practitioner ( GP ) Dispense which of the following for 30 days - Atarax 94- How many unit pancreas secrete insulin per day? - 100 units 95- Metformin used in? - Obesity Patient 96- Insulin consist of - Amino acid 97- Which insulin given IV - Regular insulin/ all rapid insulin as regular

98- Total Clearance - Vd * Kd

99- Aspirin used in treatment of rheumatoid arthritis by - It is analgesic and anti inflammatory effect 100- Mechanism of action of Warfarin - Block the release of vitamin K 101- Calamine contain - Zno 102- Which one is not true antagonist? - Tramal + Flumazenil 103- Rate of tachycardia - 100 beat/min and over 104- Addison disease is due to - Prolonged treatment with prednisolone 105- Which one is control drug? - Actfied DM 106- Which of the following inhibit absorption of anti acid containing Mg or Al element - Antacid decrease absorbtion of ciprofloxacin 107- Prozac 20 mg QID for month wanted for patient - Advice him go to back to the doctor and fix the dose (but this dose if in choices it is true) 108- Patient with hypertension have cold an OTC is contraindicated - Clarinase 109- Solution contain no micro organism - Sterile solution 110- Which one is laxative? - MGOH 111- Which one used with Haloperidol in treatment of mania and bipolar illness - Li 112- The main reason that makes us didn’t communicate with patient - Mother Tongue 113- Mupirocin is methicillin resistance used in - Staphylococcus aureus

114- Flucloxacillin is used for - Staph 115- Captopril cause - Cough 116- Controlled prescription in Sunday last day we can dispense it - Tuesday only 3 days 117- Suitable from for 18 month patient - Suspension 118- Warfarin didn’t used with green vegetables - As it contain Vitamin K 119- Treatment of Acne orally by - Minocycline 120- Which one used in Parkinson and is control medicine - Kemadrine 121- Patient take Fluxetine what period he should wait before he start Aminotryptyline - 5-6 weekes 122- Mother comes with her baby wetting bed (enureses) - Imipramine ( Tofranil ) 123- Treatment Clindamycin membranous colitis which cause Diarrhea - Metronidazole 124- Rivotril (Clonazepam) is - Controlled drug A 125- Fluoxetine is - Controlled drug B 126- Albumin serum should be controlled in patient take - Phenytoin 127- Polystyrene Sulphonate is used as Anion exchange in treatment of excess - K ( Potassium ) 128- Which one used in erectile dysfunction by topically IV - Alprostadil 129- Aspirin should be avoided in - Patient with gastritis ulcers 130- Aspirin excreted in - Alkaline NaHco3

131- Which of the following is not Aminoglycosides? - Azithromycin 132- All of the following from natural source except - Diazepam 133- Steady state definition - When the rate of infusion equal to rate of the elimination 134- Time to reach Steady state is - T half ( half life ) 135- Cephalosporin used in treatment of g –ve mainly - Cefuroxime 136- Bi compound useful as Anti acid as it inhibit - Helicobacter pylori 137- What is the intravenous dose equivalent to 500 mg of Amoxicillin given orally? - 500 mg 138-Which of the following enzyme mostly affect Codeine - Glucuronide transferase and sulfonyl transferase 139- Which of the following is a good marker for hepatic function? - Serum albumin level 140- All of the following right except - Clarithromycin is suitable to be given with patient take digoxin 141- Which of the following CYT P450 enzyme is not induced in metabolism? - CYT 5 142- Polar drug like Mannitol it is elimination rate is described by - Excretion rate 143- Drug is available as suspension which of this route is not suitable for administration - We can take it by IV 144- When giving Fluoxetine which advice is not correct? - Take with plenty of water at bed time to decrease the side effect 145- Which of the following not suitable to use with HCT + Amiloride - Losartan 146- Which of these can’t be taken with Angina? - Losartan 147- Which of these hormones required to maintaining normal Calcium concentration in the blood?

-

PTH ( Para thyroid hormone )

148- Effect of adrenaline on the heart via? - B1 149- Which of the following penicillin resistance resist to Penicillinase Enzyme? - Flucloxacillin 150- Water solubility ↑ by? - Hydroxylation 151- COP defined as - Amount of stroke volume in one minute 152- What is used with anaphylactic shock? - Adrenaline 153- We should wash our mouth after using which inhaler? - Any corticosteroid inhaler 154- Why diuretics may be useful in elderly? - To ↓ oedema and ↓ glaucoma 155- Soluble insulin + Isophane insulin - The soluble insulin appears cloudy 156- Cocaine does all of the following except: - Peripheral vasodilatation 157- Which of the following is Dopamine agonist? - Bromocriptine 158- β Blocker can used with all of the following except: - Haemodialysis 159- Which one transport Calcium from bone to blood? - PTH 160- Diavonex (Calcitriol ) for treatment of: - Psoriasis 161- Patient with hypertension + myocardial infraction - Statin + β Blocker 162- PH = - Pka+2 163- Tochopherol is vitamin: - E 164- Charcoal not absorbed

-

CN, Li or Iron

165- Not caused drowsiness on driving - Desloratadine 166- ORS contain all of the following except: - Mg(OH)2 167- Which antivirus cause chilis fever? - Interferon 168- Using of Losartan may be better than Captopril in patient have: - Cough 169- Parkinsonism due to: - ↓ Of Dopamine 170- Which of the following didn’t take orally? - Adrenaline 171- What is the test to be sure from pregnancy? - HCG 172- Gentamicin toxicity are reduced by - Using dose less than 2mg/ml 173- maximum I.M Volume - 5ml 174- What of the following is Macrolide? - Azithromycin 175- Normal saline is considered - Isotonic solution 176- .9% of normal saline equal - 0.9 gm of salt in 100 ml water 177- Composition of Combivent is - Ipratropium + Salbutamol 178- Solution of local anesthetic 1% mean - 1 gm in 100 ml 179- Patient have .25 gm Klacid bid for 7 days but .5 gm is found how many tablet should be dispense - 7 tablet 180- Best antibiotic for Urinary Tract Infection for patient have allergy to penicillin - Clarithromycin

181- What is the maximum daily dose of Voltaren? - 150 mg 182- Mother came with Aspirin 75 mg and wants to give it to her son 6 years old what’s your advice - Change it with Paracetamol 183- Legionnaires disease characterized by - Development of Pneumonia 184- Rebound congestion due to: - Otrivin 185- Patient was receiving Cefuroxime infusion then he used oral antibiotic after he went to the doctor. Patient suffers from abdominal pain, cramps, diarrhea what is the advice? - Its antibiotic associated colitis and should seek for medical assistance 186- For treatment of chronic inflammatory rhinitis - Budesonide nasal spray like Nasonex 187- If the availability of the drug is decreased due to interaction with another drug this mean - ↑ Renal excretion of the drug and decrease absorption 188- The best medicine to ↑ HDL - Nicotinic acid 189- Gliclazide - Should be taken just before food 190- Statement true about Isoniazid - Taken with pyridoxine B6 191- All of the following true except: - Diphenhydramine not best choice for motion sickness 192- Which of the following is contraindicated with Parkinson? - Phenothiazine ( Dopamine antagonist ) 193- Diazepam used for anxiety, Insomnia, Status epilepticus, Febrile convulsion dose is: - 250 micro gm /Kg 194- Expiry date is Jan 2001 last day we could use is: - 31- Jan- 2001 195- Inderal consist of - Propranolol

196- Patient with hypertension and have allergic rhinitis - Pseudoephedrine, Cetirizine alone, Cetirizine with Cetirizine 197- Patient with allergic rhinitis do all of the following except - Open window to get fresh air 198- Gentamicin have renal effect except - If dose < 2 mg/dl 199- Staphylococcus cause - Pneumonia 200- Pneumonia community acquired - Back and treatment 201- Cefuroxime absorption ↑ with - Food 202- Antidiuretic hormone antagonist - Demeclocycline 203- Amenorrhea is - Absence of menstruation 204- Dysmenorrhea is: - Painful menstruation 205- One alpha is - Alfacalcidol 206- Derivatives from Vasopressin used in bleeding from esophageal varices - Terlipressin 207- Which of the following is wrong about β blocker? - Used in treatment of hypertension in asthmatic patient 208- Insulin is being cloudy due to - Consist of soluble insulin + Isophane which is contain protamine 209- Which of the following penicillin used in Pseudomonas - Piperacillin 210- Which of the following used in pneumocystis carinii - Co-Trimoxazole 211- Crohn's disease treated by - Infliximab 212- Bisphosphonate used in

-

Treatment of Osteoporosis

213- Patient came to the pharmacy with severe pain and neuropathic give him: - Amitriptyline 214- Side effect of bromocriptine - Peripheral vasoconstriction, gangrene of toe, nausea, vomiting, constipation 215- What of the following is Al hydroxide salt indication? - Renal patient with hyperphosphatemia 216- Definition of Bioavailability - Its indicate the overall proportion of the drug that passes into systemic circulation after its administration in chemically charged form 217- Which of the following is true about stable angina? - It is one of the characteristic disease of cardiac system 218- inhaler Corticosteroids cause - Oral candidiasis 219- Which diuretics used in hypokalemia - Spironolactone 220- Prozac is used in - Obsessive compulsive disorders, Major depression 221- 7 years old have fever why we can’t give him Aspirin - Due to risk of Reye's syndrome 222- Drug used in treatment of Filariasis - Diethylcarbamazine ( orphan drug ) 223- I.V infusion means - Continuous infusion 224- Antacid inhibits the absorption of: - Bisphosphonate, Tetracycline, Warfarin, Quinolones, Ketoconazole, Digoxin, Isoniazid 225- Patient which take MAO I shouldn’t take - Tyramine 226- What is the essential amino acid? - The one who didn’t synthesized in the body 227- Which doesn’t cause blood in stool? - Irritable bowel syndrome

228- Which of the following we should wash our mouth after use - Corticosteroid inhaler 229- According to UAE the pharmacist should be training for - 1500 Hrs 230- Which organism cause Diphtheria - Cronobacter diphtheria 231- Which of the following is contraindicated in Glaucoma? - Atropine 232-Contraceptive can be take in the feeding - Cerazette as it contain Desogestrel only 233- Which is weak electrolyte? - ephedrine 234-Drug of choice of ↓ triglycerides - Fenofibrate 235- Antidote of morphine - Naloxone 236- Antidote of Benzodiazepine - Flumazenil 237- Vitamin A is - B-Carotene 238- Old man suffer from something when he pass on accident we give him - Diazepam 239- What is the best drug given in Thrombosis within 3Hrs of attack? - Altepase 240- What is the drug cause red urine? - Rifampicin 241- No problem to issue drug because - It is covered by insurance 242- The antacid that most likely to induce rebound activity - Calcium carbonate 243- Antidote for resin is - K ( Potassium ) 244- Which organism cause Sinusitis - Streptococcus pneumonia

245- Which of the following used in Penicillin resistance in sinusitis - Erythromycin 246- Volume of distribution - High tendency to the tissue 247- Solution which have osmotic pressure less than osmotic pressure of the blood - Hypotonic 248- Small volume of the intravenous drug remain not to be injected - Intradermal 249- The process of converting solid direct to vapour - Sublimation 250- Alprazolam is metabolized by - Liver 251- Excess uses of α agonist cause - Hypertension 252- Drug bioavailability alter by - Decrease gastric absorption 253- Pain originates in the centre of abdomen and spread to the lower right due to - Appendicitis 254- Which of the following is uricosuric drug? - Probenecid, benzbromarone and sulfinpyrazone 255- What is the symptom proceed the appearance of acne and lesion - Fungal infection 256- Prochlorperazine is - Antipsychotic 257- Drug used in otitis externa - Al-acetate, Chloramphenicol, Gentamicin, Clotrimazole, Neomycin, Corticosteroids 258- Drug used in otitis media - Amoxicillin, Erythromycin, Metronidazole, Aminoglycoside, Corticosteroids, Polymyxin 259- Aminoglycosides is - Amikacin, Gentamicin, kanamycin, Neomycin, streptomycin, Tobramycin 260- Which of the following used in CHF - Dexamethazone bcz it has least mineralcorticoid activity

261- Which of the following didn’t use in dandruff? - Betamethasone because it increase the dandruff 262- Which of the following stimulate cardiac? - β1 Receptor 263- What is the long acting insulin? - Ultralente 264- Acetylcholine metabolized in liver through: - Esterase 265- Antidiuretic hormone vasopressin analogue is - Desmopressin 266- One of the following didn’t effect on the efficacy of water soluble drug like Mannitol - Hydroxylation 267- Which of the following drug didn’t want Laminar Flow? - Antibiotics 268- Pregnant woman have constipation and take lactulose what is the advice we should tell her - The effect will be in 24 – 28 Hrs 269- In patient with allergic rhinitis + rhinorrhea the other symptom is - Sneezing 270- Patient suffer from palpitation and Tremors We can give him - β-Blocker 271- Drug used in clostridium difficile - Metronidazole 272- If patient have muscle pain this is due to - Simvastatin 273- Dose of Prozac is - 20 mg daily 274- Side effect of TCA all of the following except - Shortening of the breath 275- The following drug have +ve inotropic effect except - ACE-I 276- Patient have shingles from month after that she visit her doctor suffering from sever pain at same site of shingles the doctor should give her - Amitriptyline

277- One of the following used in Penicillinase producing bacteria - Co-Amoxiclav 278- Aspirin should be avoid with - Methotrexate 279- Hydrocortisone can be used in - Diaper rash 280- Drug - Drug interaction between Glibenclamide and Itraconazole is - ↑ Hypoglycemic effect of Glibenclamide 281- Benefit of using Labetalol over Phenoxybenzamine is - To avoid tachycardia

282- Patient takes Enalapril and suffers from black stool - It is side effect of Enalapril 283- Non benzodiazepine anxiolytic is - Buspirone 284- Polystyrene sulfonate used as anion exchange in excess of - K ( Potassium ) 285- Trade name of loperamide is - Imodium 286- Which of the following associated with Hypokalemia? - hyperkalemia 287- Which of the following used in treatment of hypertension in prostatic patient - Terazosin 288- In which concentration aspirin with Pka 3.6 is soluble - PH = 6 289- Which of the following is not parenterally route? - Percutaneous 290- To shift from lustral ( sertraline ) to MAO-I - 2 weeks 291- By which mechanism alcohol alter drug bioavailability - As it is enzyme inducer 292- Dose of thyroxin is - 100 – 200 microgram daily 293- The tolerance of morphine induce all of the following except

-

Constipation

294- Antifungal which take only parenterally? - Amphotericin B 295- Codeine toxicity cause all of the following except - Dilation of the eye 296- Systemic candidiasis used only in emergency room - Amphotericin B 297- For young children have diarrhea - Can wait 48 Hrs then go to doctor 298- Picrolimus is - Elidel cream 299- Daily dose of Imodium - 1 cap every 6 Hr maximum 8 cap per day 300- Proton pump inhibitor - Omeprazole, Lansoprazole, Esomeprazole, Pantoprazole, Rabeprazole 301- H2 antagonist - Cimetidine, Ranitidine, Famotidine, Nizatidine 302- Enzyme inducer - Barbiturates, Rifampin, Carbamazepine, Alcohol, Griseofulvin 303- Enzyme inhibitor - Cimetidine, Ketoconazole, Fluconazole, Chloramphenicol, Erythromycin, Fruit juice 304-

5 mg prednisolone equal to 750 mg Betamethasone 750 mg Dexamethasone 20 mg Hydrocortisone 25 mg Hydrocortisone acetate 4 mg Triamcinolone 4 mg Methyl prednisolone

305- Vitamin B1 is - Thiamine 306- Vitamin B2 is - Riboflavin 307- Vitamin B3 is - Niacin 308- Vitamin B6 is

-

Pyridoxine

309- Vitamin C is - Ascorbic acid 310- Patient currently take 220mg of anhydrous Znso4 to receive amount of elemental zinc, how many mg of ZnSO4(7H2O) would the pt have to take(Mwt Zn = 65, ZnSO4 = 161,H2O = 18) - 392 gm 311- Penicillamine antidote for - Copper and lead 312- Extracellular ions - Na, Cl, Ca 313- Intracellular ions - K 314- Antiparkinsonism has antiviral activity - Amantadine 315- Prochlorperazine used as - Antiemetic 316- The most sweetener used in chewable tablet - Mannitol 317- Theophylline should be monitored carefully when administrated with - Clarithromycin 318- Cisapride shouldn’t be used with - Clarithromycin 319- Patient with G6PD need antibiotic - Cephalexin 320- Safest tetracycline with renal failure is - Doxycycline or Minocycline 321- Otitis media is treated by - Amoxicillin 322- Otitis externa is treated by - Flucloxacillin 323-Maximum weight of recta suppository - 2 mg

324- Rectal temperature is higher than oral temperature by - 1 degree 325- Neostigmine - Used in treatment of myasthenia gravis and used only before atropine not with or after 326- Why Antipsychotic drugs are contraindicated with patient suffer from Parkinson disease - Because it is block the dopamine receptor 327- Prevent migraine in patient with peripheral vascular disease - Pizotifen 328- Why levodopa contraindicated with Vitamin B6 - Because it is break down levodopa in peripheral and diminish it is effect 329- Drug cause hirsutism - Minoxidil 330- Used in treatment of haemorrhage - Tranexamic acid 331- Highest mineral corticoid activity - Fludrocortisone 332- Most effective drug in treatment of mycoplasma - Tetracycline 333- Folic acid ↓ effect of - Sulfonamide 334- ACE-I with shortest duration of action - Captopril 335-

Uses of β-Blockers Treatment of hypertension, stable angina, hyperthyroidism Atenolol used in myocardial infraction Propranolol used in Migraine Esmolol, sotalol used in Cardiac arrhythmia Timolol used in treatment of glaucoma

336- Best choice in treatment of salmonella - Tetracycline or macrolide (chloramphenicol not used now) 337- Treatment of hypertension patient with Asthma - Amlodipine 338- Interaction of the Amiloride with Captopril - Hyperkalemia

339- Ophthalmic solution PH - 6 to 8 340- NE reuptake inhibitor of Tertiary amine ( TCA ) - Amitriptyline, Imipramine, Clomipramine 341- NE reuptake inhibitor of secondary amine ( TCA ) - Nortriptyline 342- Serotonin reuptake inhibitors - Citalopram, Escitalopram, Fluoxetine, Fluvoxamine, Paroxetine, Sertraline 343- Antidepressant drug work by - D2 receptor antagonist 344- Acetazolamide used in epilepsy but - Tolerance comes in 4 month 345- What is the primidone? - Similar to Phenobarbital converted in liver to Phenobarbital 346- Which of the following drug ↑ excretion of antacid drug - Na bicarbonate 347- What is wrong about amenorrhea? - Have 2 type and both have the same reason 348- Which of the following is natural emulsifying agent? - Acacia 349- Which of the following decrease diastolic pressure - Isoprenaline 350-Biotin: - Known as vitamin H or B7 ( water soluble vitamin B ) 351- Patient suffer from palpitation give him - β-Blocker 352- Antidote for poisoning of pesticide - Atropine, Pralidoxime 353- Potassium sparing diuretics - Amiloride, Triamterene, Spironolactone, Eplerenone 354- tetracycline or macrolide is drug of choice in treatment of - Salmonella infection 355- Benzhexol, Benztropine, Procyclidine have

-

Antimuscarinic activity

356- Which of the following drug is safe in treatment of either constipation or diarrhea - Polycarbophil 357- Essential amino acid - Valine 358- Semi essential amino acid - Arginine, Histidine 359- Hypnotic cause Amnesia - Triazolam 360- Drug of choice in treatment of Obsessive compulsive disorders - SSRI 361- Drug cause lupus erythematosus - Hydralazine, procainamide 362- Drug of choice in treatment of status epilepticus - Lorazepam 363- Best choice in treatment of Grand mall seizures - Phenytoin + Carbamazepine 364- Best choice in treatment of petit mall seizures - Na Valproate 365- Best choice in treatment of simple partial seizures - Carbamazepine 366- Best choice in treatment of complex partial seizures - Carbamazepine 367- Best choice in treatment of mixed seizures - Na Valproate

HAAD exam June 2011 368- Ibuprofen dose in 30 kg child - 1200 mg / day 369- Hyper-calcemia is above - 10.5 mg/dL 370- All are Risk factors for Breast cancer except - (early menopause, obesity, late age of first child, family History) 371- Saline treatment of hypercalcemia is at a rate of

-

300 ml/hr

372- Causes of hypercalcemia - Increased PTH and Malignancy 373- Treatment of UTI in pregnancy - (Cephalexin, Macrolide, ciprofloxacin) 374- Treatment of UTI in pregnancy - Augmentin 375- Treatment of Neisseria Meningitis - (Ampicillin, Nafcillin, Vancomycin, Gentamicin) 376- Eye pain, Halo, headache means - (cataract, glaucoma, viral infection) 378- Smoking affects theophylline by - Increasing its metabolism 379- Drugs used in syphilis except - (Azithromycin, Benzyl penicillin, Doxycycline, Ceftriaxone) 380- Prostatitis drug of choice - (Ciprofloxacin, Doxycycline....) 381- Nifedipine not used in - (Pre-eclampsia, early abortion, angina, HTN) 382- Insulin NPH given with regular insulin Bid, with morning fasting glucose increase - (change NPH to Bed time) 383- Sulfonylurea is - Insulin secretagogue 384- NPH insulin change to longer duration - (Glargine, Detemir, …) 385- Thiazolidinedione used in DM - (Rosiglitazone) 386- Carbimazole side effect - (Agranulocytosis, Bone marrow suppression,...) 387- Primary cause of 2ry HTN in children - (Cushing syndrome, Renal disease, liver, aortic disease) 388- Gastric pain after heavy meal radiating to the neck and lower jaw - (Duodenal Ulcer, Atypical angina, Gastric cancer) 389- Most potent topical corticosteroid

-

(Clobetasol, Betamethasone)

390- Treatment of impetigo - (Fusidic acid, Mupirocin, both) 391- HZV patient wants to stop treatment, advise him - (Therapy will reduce recurrence, Severity, Spreading to the rest of the body, Post herpetic neuralgia) 392- Patient on multiple treatment including Omeprazole, change it to - ( Cimetidine) 393- Patient on Cefuroxime and celecoxib got diarrhea - (Post antibiotic pseudomembranous colitis) 394- Bacterial vaginosis dose of Metronidazole single dose - (2g, 1 g, 500 mg, 200 mg) 395- Typhoid fever drug of choice - (Chloramphenicol, Cipro, Septrin) 396- Orlistat patient counseling - (Need prescription, Refer to doctor, Counsel about diet and life style) 397- Cromolyn nasal spray in rhinitis counsel patient about - (How long u use it, How to use it, Inhale after it) 398- Diazepam storage condition - (Room temp ,Sealed plastic container, Protect from light) 399- Clostridium difficile treatment with - Metronidazole 400- Narcotic prescription is valid for - 3 days 401- Cocaine toxicity includes the following except - (Euphoria, Wide pupil, Tachycardia, Peripheral vasodilatation) 402- Laxatives interact with absorption of - (B1, B2, Vit C, Fat soluble vitamins) 403- Thiazide side effect because increased execration of - (Na, K, Ca) 404- Diuretics interact with execration of - (ASA) 405- Sympathomimetics used cautiously with - (HTN, DM, Angina)

406- MAOI used with decongestants can cause - (HTN crisis) 407- MAOI interact with - (TCA, Decongestants, Appetite suppressants...) 408- Ramipril initial daily dose - (2.5 mg OD, 25 mg, 50 mg, 100 mg) 409- Dose to consult physician - ( Ramipril 12.5 mg BD) 410- Indomethacin dose in gout - 25-50 3-4 times daily 411- Patient injured by wire what question you ask - (Did you take tetanus vac. in last 10 years, Go to doctor, Was the wire dirty) 412- Nifedipine not indicated in - (A.Fib, HTN, Angina) 413- Stage I hypertension treatment - ( Thiazide, ACEI, BB, CCB) 414- Motion sickness in car drive advise - (Eat heavy metals, Sit in front sea ,Close window , Do not look from window) 415- NSAIDs interacts with - All antihypertensive 416- High risk of nosocomial infection - (Surgery, Ventilator, Hospitalized more than 10 days) 417- Drugs less likely to be execrated in milk - (Low fat solubility) 418- Patient on sumatriptan not effective - (Give another dose after 2 h, Give ergot within8 h) 419- Methicillin-resistant Staphylococcus aureus (MSSA) drug of choice - (Vancomycin, Penicillin, Nafcillin) 420- Sulfasalazine is made of - (Sulfapyridine and Aminosalicylic acid) 421- Antidote of Paracetamol is - Acetyl Cysteine

422 - Sulfasalazine daily dose is - 8 grams 423- Chemotherapy induced nausea and vomiting - Dexamethasone 424-Used in chemotherapy induced nausea and vomiting - ( Selective serotonin receptor antagonist, Antacid, Dexamethasone) 425- Patient using spacer and β agonist. What is the recommended action? - (Leave finger space between mouth and spacer, Take quick breath at the same time as pressing the canister) 426- Meclizine dose in motion sickness how often - (1-2 Hrs, Q 4 Hrs, 8 Hrs, 24 Hrs) 427- D.O.C in myoclonic seizure ( - (Valproate, Phenytoin, Carbamazepine, Lamotrigine)

HAAD exam of OCT 2010 428- Thiazolidinedione is drugs use for - Diabetes 429- Alprazolam is - Short/intermediate half life 430- Tetracycline and antacid - Separate for 2 hours 431- Moon face is symptom of - Cushing syndrome 432- Levothyroxine dose adjustment according to - Age 433- Not associated with salbutamol - Pain at inhalation 434- Not side effect of anti muscarinic - Diarrhea 435- Amlodipine is used for all of the following except - Angina, Pre eclampsia, Premature labour

436- Nausea Vomiting associated with chemotherapy treated by - Dexamethasone 437- To maintain remission phase after acute attack of ulcerative colitis - (Prednisolone ,Sulfasalazine, Hydrocortisone) 438- Advise for the user of aerosol inhaler of corticosteroids - Wash your mouth after using the aerosol 439- Disease caused by staphylococcus - Impetigo 440- For which type lipid dysfunction is Lipitor used for - Types IIa and IIb 441- A property of bulk forming laxatives is - Bran and Psyllium 442- Pentoxiphylline for diabetic patient with - Peripheral vascular disease 443- Mechanism of Acarbose is - Alpha-glucosidase inhibitors 444- Side effect of Carbimazole is - Sore throat due to agranulocytosis caused by drug 445- Life threatening condition of hypersensitivity cause skin cells to separate from dermis - Steven Johnson syndrome 446- Drug of malaria - Primaquine 447- Swelling in one leg with erythema indicates - DVT 448- Cause and treatment of pneumonia - Mycoplasma pneumonia + Azithromycin, Mycoplasma pneumonia + Fluoroquinolones, Pseudomonas aeruginosa +Azithromycin, Pseudomonas aeruginosa + Fluoroquinolones 449- Patient is suffering from pain that is relieved by eating the reason will be - Duodenal ulcer, Stomach ulcer, Stomach cancer 450- Contraindicated in pregnancy - Vit A 451- Patient treated with levothyroxine will notice the following improvement

-

(Decrease in weight, High energy)

452- Side effect of nitroglycerine - Throbbing pain 453- MAOI +pseudoephedrine - HTN crisis 454- Piroxicam side effect - Stomach bleeding 455- Breast cancer treatment - Tamoxifen 456- Shingle caused by - Herpes Zoster 457- If we change from IV to oral rate, which drug of the following should increase its dose - Propranolol 458- Trade name of athlete’s foot is - Lamisil 459- Which drug cause cough? - Enalapril 460- Corticosteroids inhalers advised by all except - Clean mouth after inhalation, Leave 10 sec after inhalation, Take quick breath 461- Patient with allergic rhinitis best advised by all except - (Remove carpet, Clean vacuum regularly, Open window to get fresh air, Wash linen beds with hot water) 462- Patient taking theophylline which advice given to him - Do not crush the tablet 463- Clozapine causes - Agranulocytosis 464- Vitamin A: derived from - Beta-carotene 465- Diazepam rectally for fibril convulsion for child wt 22 kg - 12.5 mg, 25 mg, 50 mg 466- Drug acts as enzyme inhibitor on the first dose: - (Diazepam, Salbutamol, Enalapril, Glyburide)

467- Which of the following is prodrug? - Enalapril 468- If patient miss dose of drug used before breakfast so - (Use when he comes back to home, Use lunch dose, Use double dose on lunch) 469- Athlete’s Foot symptoms are except - (Itching, Peeling of skin, White patch between toes, Bad odour) 470-If the drugs has large volume of distribution, it mean - (Highly bounded to plasma protein, Highly distributed in the tissues , Short half life time) 471- All of these drugs are racemic isomer except - (Amphetamine, Bupivacaine, Cetirizine, Loratin, Citalopram, Ofloxacin, Omeprazole, salbutamol, levobupivacaine) 472- All of these drugs are single enantiomer except - (Dextroamphetamine, levocetirizine, Desloratadin, Levofloxacin, Escitalopram, Esomeprazole, Levalbuterol - Omeprazole) 473- Amoxicillin 500mg orally used if doctor shifted to IV ,what the dose - (1g, 500mg, 250mg, 125mg)

474- Hydrochlorothiazide/Amiloride contraindicated with - (Losartan, Salbutamol, Diazepam) 475- Disease caused by illy fitted shoes - (Highly pressure, corn, cold sore, athletes) 476- Diphenhydramine used except - (Best choice for morning nausea, Used with cough prep, Used for motion sickness) 477- Alprazolam storage (25c, keep from light, Tight the bottle) 478- Athletes is foot treated with - (Clotrimazole, Griseofulvin, Nystatin) 479- Laminar air flow, which one used for antibiotic and which one for cytotoxic agent Horizontal for Antibiotic - Vertical for Cytotoxic 480- Diazepam acts on - GABA receptors

481- More than 20 cigarettes: - Use nicotine 4mg gum every one hour 482- Levothyroxine should be taken - On empty stomach 2 hours from ca containing products 483- Mechanism of action of heparin: - Activate antithrombin 484- Drugs used to help remission in ulcerative colitis: - Sulphasalazine 485- Binding to albumin - Drugs that bind to albumin are weak acids 486- Why Methylcellulose are added to drops - To increase intraocular contact time 487- Acetylcholine and Succinylcholine metabolized by - Ester hydrolysis 489- Transfer into breast milk: - Use lipophilic drugs (basic drugs) 490-Before giving Interferon: - Check TB 491- Equivalent dose of Atorvastatin to Simvastatin: - Half of the strength of Simvastatin. (10mg of Rosuvastatin = 20mg atorvastatin = 40mg Simvastatin) 492- Mechanism of Ritonavir: - Enzyme inhibitor 493- Who can dispense narcotics? - Only pharmacist, Technician cannot dispense even if a pharmacist double check 494- Pharmacy business success is assessed by - Inventory turnover 495- Mechanism of action of Sitagliptin - It is work as Dipeptidyl peptidase-4 inhibitors 496- Aminoglycoside nephrotoxicity ↑ by - (Diuretics, Ibuprofen, Vancomycin) 497- Which one is not chelating agent - (Amikacin, Cisplatin, Lactulose, Hemoglobin) 498- Kwashiorkor is? - An acute form of childhood protein-energy malnutrition

499- Mechanism of action of Hydralazine - Direct acting Vasodilator 500- Mechanism of action of nitrates - Have a direct relaxant effect on vascular smooth muscles, and the dilation of coronary vessels improves oxygen supply to the myocardium 501- Narcotic book kept for - 5 years 502- Tamiflu is - Oseltamivir 503- Drug cause anemia - (Methotrexate, Phenytoin, Rifampicin) 504- Ibuprofen - (Used in first trimester, Contraindicated in women, Can be used if benefit more than risk) 505- Scabies treatment - Permethrin 5% 506- Human Papilloma virus cause - cervical cancer 507- Wart caused by - Human Papilloma virus 508- Sumatriptan is - 5HTA agonist 509- Man come from Africa suffer from too much sleep - Narcolepsy 510- Buspirone is - 5HT1 Partial agonist 511- Mechanism of action of Mebendazol - Deplet energy of parasit 512- If you work in hospital pharmacy and dispense narcotic drug but they didn’t use all the dose what you should do with the returned dose - (Put it back on the stock, Throw it away, Execute it with presence of witness and put that in the report) 513- Formula of paraffin to 100% have 1% A, 15% B, 12% starch how many grams of the paraffin needed to form 250 mg of this formula - 180 gm 514- In GABA receptors which of this is guard the channel - (K, Cl, Ca, Na)

515- What is the K normal concentration in the blood? - 3.5 to 5 516- Which medicine can’t be taken with pregnant women due to depletion of Folic Acid? - (Phenytoin, Trimethoprim, Warfarin, Cholestyramine) 517-Mechanism of Azithromycin - Interfering with their protein synthesis, It binds to the 50S subunit of the bacteria 518- Arrange the following Ascending from less to more important - Case report < Case study < Case control < Cohort 519- Arrange the following agent from higher to lower acidity - Acquaragia > Sulfuric acid > Distilled water > Na Bicarbonate 520- Metaproternol salt 15mg/ml (mwt 520, base 211) How much % strength of base in the solution - 0.6% 521- Patient come with old prescription and want to repeat the antibiotic and the pharmacist with you tell you it is ok I know him give him the medicine - You will give him the medicine - Give him the medicine because your boss know him - Refuse to dispense the medicine and report the Haad 522- Nadir went to hospital with his father, Maher is Nadir friend and came to you in the pharmacy to ask about Nadir - Tell him about Nadir case - Tell him little information about the case - Don’t tell him any information and tell him to ask physician - Tell him about the case because Nadir father with him 6 5 4

4 2

2 1.1

0 0.5

0 1

1.5

2

2.5

3

3.5

523- Drug C is - (Agonist, Antagonist, Partial agonist, Partial antagonist)

4.5 4

4

3.5 3

3

2.5

Iv dose

2

Oral dose

1.5 1 0.5

1 0.8

0.5 0.3

0 0

0.5

1

1.5

2

2.5

3

The IV dose Area under the curve = 11.4 Oral dose Area under the curve = 5.2 524- Find the Cmax for the IV dose - 4 525- Find T half for the oral dose - 1.5 526- Find the percentage of oral bioavailability - Bioavailability equal to area under the curve so we will take area under the area under the curve for oral dose areaunder the curve of the Iv dose

* 100

5.2 11.4

*100 = 45.6%

527- If the specific gravity of glycerin equal to.86 what is the weight of the 250 ml of glycerin w ρ= So v =ρ∗w 250 * .86 = 215 v