Chronic Obstructive Pulmonary Disease (COPD) Pathophysiology

Schematic Diagram Pathophysiology (Book-based) COPD and Tuberculosis Non- Modifiable Factors

Modifiable Factors

Age

Environment Work

Sex Genetic Predisposition

Smoking

Primary Infection

Inhalation m. tuberculae Infecting tuberculae bacilli phagocytosed Carried into regional broncho pulmonary lymnodes

Necrotic degeneration Cavities filled with cheese mucus and dead blood cell

Impaired lung clearance Bronchial inflammatory airway obstruction

Alveolar hypoventilation Weakened disruption Collapse of small airways in expiration

Drain into trcheobronchial tree Chronic bronchitis

emphysema