Bioanalyse - Zone Table (Expanded)

 

 

Interpretive Standards (mm)  (mm) 

 An ti mi micr cr ob ial Ag ent Code *Microorganism

Content Disk

R

I

S

(Resistant)

(Intermediate)  

(Susceptible) 

Control Zone Diameters (mm) E. coli  ATCC 25922

S. aureus  ATCC 25923

P. aerugi aerugi nosa  ATCC 27853 

We Bioanalyse® Limited hereby declare that our AST Discs are to be evaluated according to below given clinical and QC parameters:   Am ik aci n (a) 

 AK -30

30 µg

*Enterobacteriaceae *P. aeruginosa *Acinetobacter *Staphylococcus spp.   Am ik aci n (16)  

13

14-17

>18

*Staphylococcus spp.

20

*Haemophilus spp.

20

 Am pi ci ll in

AM-10

10 µg

*Enterobacteriaceae and V. cholerae

17

*Staphylococci spp.

29

*Enterococcus spp.

17

*Haemophilus spp.

22

*Streptococci (non-S. pneumonia) 

26

---

---

>24   >24

*Streptococci (ß-hemolytic only)  only)   Am pi ci ll in /su lb act am

SAM-20

18-26

18-24

---

---

22-26,5

---

---

18-24

28-36

---

16-22

27-35

---

19-24

29-37

---

60 60  µg  µg  

*Enterobacteriaceae *Staphylococcus spp.   Am ox ic il li n (7) 

20-26

>17

10 µg

*Enterobacteriaceae *P. aeruginosa *Acinetobacter *Staphylococcus spp.  spp.   Am in os osid id in (7) (c) 

15-16

19-26

10/10 µg

*Enterobacteriaceae *P. aeruginosa *Acinetobacter and staphylococci 

15

*Haemophilus spp.

20

 Ap ram yc in (6) 

 APR-15

15 µg

15-20

17-24

13-18

 Azi th ro myci my ci n

AZM-15

15 µg

---

21-26

---

---

---

24-30

28-36

---

23-29

*Staphylococcus spp. *Haemophilus spp. *S. pneumoniae and other streptococci *Neisseria meningitidis  Azl oc ocilil li n

AZL -75

14-17

>18

---

---

>12

18

---

---

>20

75 µg

*P. aeruginosa  Azt reo nam

26

*Haemophilus spp.

Page 1 / 16 16  

 

 

Interpretive Standards (mm)  (mm) 

 An ti mi micr cr ob ial Ag ent Code *Microorganism

Bacitracin(5) 

B-10

Content Disk

I

S

(Resistant)

(Intermediate)  

(Susceptible) 

10 U

*E. coli *P. aeruginosa *S. aureus Carbeni cil li n

R

18

CFR-30

30 µg

14-20

---  --- 

---

MA-30

30 µg

26-32

26-34

---

21-27

29-35

---

24-28

25-32

---

31-37

23-29

24-30

23-27

---

---

---  --- 

---  --- 

---  --- 

25-29

22-28

---

  Cefamandol e *Enterobacteriaceae and Staphylococcus spp.   spp. Cefazolin

18

30 µg

*Enterobacteriaceae

Cefdin ir

15-17

20

---

---

>20

30 µg

*Enterobacteriaceae,  *Enterobacteriaceae,  *P. aeruginosa,  aeruginosa,  *Acinetobacter and staphylococci,  staphylococci, 

18

*Haemophilus spp.

---

---

>26

*N. gonorrhoeae.

---

---

> 31

*Viridans streptococci (non-S. pneumoniae)

24

*Streptococci (non-S. pneumoniae, ß Hemolytic only 

---

---

19

---

---

>21

30 µg

*N. gonorrhoeae Cefoni ci d

31

30 µg

*Enterobacteriaceae   *Enterobacteriaceae

18

*Haemophilus spp.  spp. 

20

*Staphylococcus spp.  spp. 

18 Page 2 / 16 16  

 

 

Interpretive Standards (mm)  (mm) 

 An ti mi micr cr ob ial Ag ent Code *Microorganism

Cefoperazone   Cefoperazone

CEP-75

Content Disk

(13)

 

I

S

(Resistant)

(Intermediate)  

(Susceptible) 

75 µg

*Enterobacteriaceae *P. aeruginosa *Acinetobacter and Staphylococcus spp.  Cefoperazone/ sulbactam

R

21

75/30 µg

*Enterobacteriaceae *Acinetobacter

20

Cefotaxime(18)  

CTX-5

5 µg

25-31

---  --- 

---  --- 

Cefotaxime   Cefotaxime

CTX-30

30 µg

29-35

25-31

18-22

*P. aeruginosa *Acinetobacter and Staphylococcus spp. 

23

*Enterobacteriaceae

26

*Haemophilus spp.

---

---

>26

*N. meningitidis

---

---

>34

*N. gonorrhoeae

---

---

>31

---

---

>24

28

*Streptococci (non-S. pneumoniae, ß-Hemolytic only) *Viridans Streptococci (non-S. pneumoniae)  Cefotaxime/ (e)  Cefotaxime/ clavulanic acid

CTC-40

30/10 µg

---  --- 

---  --- 

---  --- 

Cefotetan  

CTT-30

30 µg

28-34

17-23

---

23-29

23-29

---

---

--- 

---

23-28

19-25

---

21-27

27-33

---

*Enterobacteriaceae, *Staphylococcus spp.  spp. 

16

*N. gonorrhoeae

26

Cefoxi tin

FOX-30

30 µg

*Enterobacteriaceae

18

*Staphylococcus aureus

22

*N. gonorrhoeae

28

Cefpirome (7) 

CPO-30

30 µg

*Enterobacteriaceae

24

P. aeruginosa

19

*Acinetobacter

21

Cefpod oxi me

CPD-1 CPD-10 0

10 µg

*Enterobacteriaceae *Staphylococcus spp.

21

*Haemophilus spp.

---

---

>21

*N. gonorrhoeae

---

---

>29

Cefprozil   Cefprozil

CPR-30

30 µg

*Enterobacteriaceae and Staphylococcus

18

*Haemophilus spp.

18

Page 3 / 16 16  

 

 

Interpretive Standards (mm)  (mm) 

 An ti mi micr cr ob ial Ag ent Code *Microorganism

Content Disk

R

I

S

(Resistant)

(Intermediate)  

(Susceptible) 

Control Zone Diameters (mm) E. coli  ATCC 25922

S. aureus  ATCC 25923

P. aerugi aerugi nosa  ATCC 27853 

Cefqui nom e

CEQ-30

30 µg

28-36   28-36

25-33   25-33

---  --- 

Cefsulodin(17) 

CFS-30

30 µg

---  --- 

---  --- 

---

*P. aeruginosa Ceftazidime (18) 

22

CAZ-10

10 µg

23-29

---  --- 

---

CA Z-30

30 µg

25-32

16-20

22-29

---  --- 

---  --- 

27-35

---

---

26-31

27-31

14-18

30-36

27-35

12-17

29-35

22-28

17-23

20-26

27-35

---

20-26

27-35

---

  Ceftazidi me *P. aeruginosa *Staphylococcus spp. and Acinetobacter

< 14

15-17

> 18

*Enterobacteriaceae

< 17

18-20

>21

*Haemophilus spp.

---

---

>26

*N. gonorrhoeae

---

---

>31

< 17

18-20

>21

*B. cepacia Ceftazidime/(e) clavulanic acid Ceftibuten   Ceftibuten

CZC-40   CZC-40 CBT-30

30/10 30 µg

*Enterobacteriaceae *Haemophilus spp. Ceftiofur

(3)

 

FUR-30

18-20

>21

---

---

>28

30 µg

*E. coli *S. aureus *Streptococcus spp. Ceftizoxime   Ceftizoxime

26

*N. gonorrhoeae

---

---

>38

Ceftri axone

CRO-30 CRO-30

30 µg

*P. aeruginosa *Acinetobacter and Staphylococci

21

23

*Haemophilus spp.

---

---

>26

*N. meningitidis

---

---

>34

*N. gonorrhoeae

--

---

>35

< 24

25-26

>27

---

---

>24

*Enterobacteriaceae

*Viridans Streptococci non-S.. neumonia non-S neumoniae e *Streptococci (non-S. pneumoniae, β-Hemolytic only) Cefuroxime (sodium)  (sodium) 

CXM-30

30 µg

*Enterobacteriaceae and staphylococci (parenteral)   (parenteral)

18

*Haemophilus spp.

20

*N. gonorrhoeae

31

Cefuroxime  (axetil) Cefuroxime (axetil)  

CXA-30

---  --- 

30 µg

*Enterobacteriaceae and staphylococci (oral)

23

*Haemophilus spp.

20 Page 4 / 16 16  

 

 

Interpretive Standards (mm)  (mm) 

 An ti mi micr cr ob ial Ag ent Code *Microorganism

Cephalexin(10) 

CL-30

Content Disk

Cephalothin   Cephalothin

CL-30

KF-30

15-17

30 µg  µg   ---

30 µg

13-17

>18

*Haemophilus spp.

< 25

26-28

>29

*N. meningitidis

26

*S. pneumonia

21

*Streptococcus spp. (non-S. pneumoniae)

21

30 µg  µg  

*Enterobacteriaceae *P. aeruginosa *Acinetobacter *Staphylococcus spp. Cinoxacin   Cinoxacin Ciprofloxacin   Ciprofloxacin

31

---

---

>21

*N. meningitidis

< 32

33-34

>35

*N. gonorrhoeae

< 27

28-40

>41

Clarithromycin   Clarithromycin

CLR-15

15 µg

*Staphylococcus spp.

18

*Haemophilus spp.

13

*S. pneumoniae and other streptococci

21

Clin damyc in

DA-2

2 µg

*Staphylococcus spp.

21

*S. pneumoniae and other streptococci  streptococci 

19

Cloxacillin (10) 

*S. aureus *Staphylococcus spp.

CX-5

---

---  --- 

---  --- 

---  --- 

21-27

19-26

---

---

---

---

26-32

---

---

30-40

22-30

25-33

---

26-32

---

---

24-30

---

---

26-32

---

5 µg

19

5 µg

*Enterobacteriaceae (except for Salmonella spp.) *P. aeruginosa *Acinetobacter *Staphylococcus spp. *Enterococcus spp.

29-37

>23

100 µg

*Enterobacteriaceae

15-21

 

18

18

*Enterobacteriaceae * P. aeruginosa *Acinetobacter *Staphylococci * V. cholerae *Enterococci

(7)  Chloramphenicol (According to SFM)  SFM)  

P. aerugi aerugi nosa  ATCC 27853 

>18

30 µg

22

15 µg

*Staphylococcus spp.

19

*S. pneumonia *Streptococcus spp. (β-hemolytic group)

18

Dibekacin (17) 

DBK-10

10 µg

*Enterococcus spp. *Staphylococcus spp. (S. pneumoniae is excepted) Dori penem

16

10 µg

*Enterobacteriaceae

23

*P. aeruginosa

19

---

---

>16

*Haemophilus spp. Doxycycline   Doxycycline

DO-30

30 µg

*Enterobacteriaceae

14

*Acinetobacter  

13

16

28

*P. aeruginosa *Staphylococcus spp. and Enterococci  Enterococci  *S. pneumonia Enoxacin  

EN-10

10 µg

*Enterobacteriaceae and Staphylococcus *N. gonorrhoeae Enrofloxacin

(2)

 

ENR-5

>18

36

20

10 µg

*Enterobacteriaceae   *Enterobacteriaceae Erythromycin   Erythromycin

15-17

5 µg

*Mannheimia haemolytica *Pasteurella multocida *Histophilus somni Ertapenem

19

15 µg

*Staphylococcus spp. and enterococci  enterococci 

23

*S. pneumoniae and other Streptococcus spp.

21

18

Flucloxacillin (f)  *Staphylococcus spp. Flumequine (7) 

FL-5 FLM-30

5 µg 30 µg  µg  

*Enterobacteriaceae Fosf omy ci n *E. coli and E. faecalis

< 21 FF-200 FF-200

---

> 25

200 µg 16 Page 6 / 16 16  

 

 

Interpretive Standards (mm)  (mm) 

 An ti mi micr cr ob ial Ag ent Code *Microorganism

Framycetin (7)(c) 

FM-100

Content Disk

Fusidic Acid (10)

I

S

(Resistant)

(Intermediate)  

(Susceptible) 

18

*N. gonorrhoeae

38

*S. pneumoniae and other streptococci

21

*Enterococcus spp. *H. influenzae and H. parainfluenzae

Gentamicin (g) 

CN-120

120 µg  120  µg  

*Testing enterococci (for high level resistance)   resistance) Gentamicin   Gentamicin

15

10 µg

*Acinetobacter 16

*Enterobacteriaceae

23

*P. aeruginosa

19

---

---

>16

*Haemophilus spp. Isepamicin

(17)

 

ISP-30

30 µg

*Enterobacteriaceae *Acinetobacter spp. *P. aeruginosa Kanamycin (a)  Kanamycin 

18

10 IU

17

Page 7 / 16 16  

 

 

Interpretive Standards (mm)  (mm) 

 An ti mi micr cr ob ial Ag ent Code *Microorganism

Levofloxacin   Levofloxacin

LEV-5

Content Disk

R

I

S

(Resistant)

(Intermediate)  

(Susceptible) 

5 µg

*Enterobacteriaceae *P. aeruginosa  aeruginosa  *Acinetobacter *Enterococci *Staphylococci *Haemophilus spp.

17

19

---

---

>17

17

Control Zone Diameters (mm) E. coli  ATCC 25922

S. aureus  ATCC 25923

P. aerugi aerugi nosa  ATCC 27853 

29-37

25-30

19-26

27-33

23-29

22-28

---

25-32

---

23-29

23-31

---

29-37

24-30

20-25

---

---

---

*S. pneumoniae and other streptococci (non-S. pneumoniae, ß-Hemolytic only) Lomefloxacin   Lomefloxacin

LOM-10

10 µg

*Enterobacteriaceae *P. aeruginosa *Staphylococcus spp. *Acinetobacter *Haemophilus spp.  spp.  *N. gonorrhoeae Lin ezoli d

LNZ-30

22

---

---

>22

38

30 µg ---

*Staphylococcus spp.

< 20

*S. pneumoniae and other streptococci

---

---

>21

< 20

21-22

>23

*Enterococcus spp. Lor acarbef

LOR-30

>21

30 µg

*Enterobacteriaceae *Staphylococcus spp.

18

*Haemophilus spp.

19

Marbof lox acin

MAR-5

5 µg

*Enterobacteriaceae *Staphylococcus spp. Mecillinam (7) 

20

10 µg

*Enterobacteriaceae (18)

15-19

18

MEC-10

10 µg

24-30

---

---

MEM-10

10 µg

28-34

29-37

27-33

---

17-22

---

23-29

---

19-25

19-25

25-30

---

28-35

18-24

17-25

*Staphylococcus spp. *Acinetobacter

16

*Enterobacteriaceae

23

*P. aeruginosa

19

*N. meningitidis

---

---

>30

*Haemophilus spp.

---

---

>20

Methicill in

ME-5 ME-5

5 µg

*Staphylococcus aureus   aureus Mezlocillin   Mezlocillin

< 10 MEZ-75

13

75 µg

* Acinetobacter   Minocycline   Minocycline

11-12

18-20

>21

30 µg

*P. aeruginosa *Staphylococcus spp. *Enterococci   *Enterococci

19

*Acinetobacter *Enterobacteriaceae

16

---

---

>26

*N. meningitidis Moxalac tam

MOX-30

30 µg 23

*Staphylococcus spp.

Page 8 / 16 16  

 

 

Interpretive Standards (mm)  (mm) 

 An ti mi micr cr ob ial Ag ent Code *Microorganism

MXF-5

Moxifloxacin

Content Disk

R

I

S

(Resistant)

(Intermediate)  

(Susceptible) 

5 µg

*Enterobacteriaceae

19

---

---

>18

*Staphylococcus spp.

24

*S. pneumoniae

18

*H. influenzae *H. parainfluenzae

Mupirocin (7) 

MUP-5

5 µg  µg  

* Staphylococcus spp. *S. saprophyticus *S. xylosus *S. cohnii (intrinsic resistance)

Nafcil li n

---

NAF-1

13

30 µg

*Enterobacteriaceae

E. coli  ATCC 25922

>19

1 µg

*Staphylococcus aureus   aureus

Nalidixic Nalidixic Acid Acid  

---

Control Zone Diameters (mm)

>19

(18)

Netilmicin

 

Netilmicin   Netilmicin

NET-10

10 µg

18-24

---

15-21

NET-30

30 µg

22-30

22-31

17-23

17-23

18-26

---

---

22-31

---

*Enterobacteriaceae *P. aeruginosa *Staphylococcus spp.  spp.  Neomycin (3) (a) 

17

30 µg

(Muller Hinton agar with sheep blood for veterinary) in use

17

Nitrofurantoin(18) 

F-100

100 µg

17-23

---

---

Nitrofurantoin   Nitrofurantoin

F-300

300 µg

20-25

18-22

---

28-35

17-28

22-29

29-33

24-28

17-21

*Enterobacteriaceae *Staphylococcus spp. *Enterococcus spp. Norfloxacin   Norfloxacin

17

5 µg

*Enterobacteriaceae *P. aeruginosa *Acinetobacter and

16

*Staphylococcus spp.

18

---

---

>16

*N. gonorrhoeae

< 24

25-30

>31

*S. pneumoniae and other streptococci (non-S. pneumoniae, ß-Hemolytic)

16

*Haemophilus spp.

Page 9 / 16 16  

 

 

Interpretive Standards (mm)  (mm) 

 An ti mi micr cr ob ial Ag ent Code *Microorganism

Oleandomycin (11) 

OL-15

Content Disk

R

I

S

(Resistant)

(Intermediate)  

(Susceptible) 

15 µg 20

Oxolinic acid

(5)

OA-2

 

2 µg µg  

*Enterobacteriaceae Oxolinic acid

(a)

28

P-10

10

*Staphylococcus spp.

< 28

---

>29

*Enterococcus spp.

15

*N. gonorrhoeae

47

*Streptococci (non-S. pneumoniae)

28

*Streptococcus spp.

---

---

>24

*S. pneumoniae

---

---

>20

Piperacillin/ tazobactam (18)  Piperacillin/ tazobactam

---  --- 

---  --- 

---

18-24

---

20-24

10-13

---

>30

*Streptococcus spp. *Enterobacteriaceae

Penicillin   Penicillin

---  --- 

---  ---  11

2 µg

*Aeromonas salmonicida Oxytetracycl ine

---

S. aureus  ATCC 25923

>17

1 µg

*S. pneumonia (for penicillin G susceptibility)

E. coli  ATCC 25922

---  --- 

---  --- 

---  --- 

---

26-37

---

TPZ-36

36 µg

21-27

---  --- 

23-29   23-29

TPZ-100/10

100 /10

24-30

27-36

25-33

*Enterobacteriaceae *Acinetobacter spp.

21

*P. aeruginosa *H. influenza *H. parainfluenzae

>21

Piperacillin   Piperacillin

PRL-30

30 µg

21-27

---

---

Piperacillin   Piperacillin

PRL-100

100 µg

24-30

---

25-33

29-35.5

25.5-29.5

---

---  --- 

---  --- 

---  --- 

---

15-19

---

12-16

---

---

*Enterobacteriaceae *Acinetobacter spp.

21

*P. aeruginosa

21

Pefloxacin (7) 

PEF-5

5 µg

*P. aeruginosa *Acinetobacter spp. *Staphylococcus spp.  spp.  Pipemidic Pipem idic acid

(2)

 

22

20 µg  µg  

*Enterobacteriaceae (1) (3)

---

---

≥ 13

300 U 19

* Enterococcus faecalis (Vancomycinsusceptible)

---

---

>19

19

23

*Enterobacteriaceae (7)(b)

Thiamphenicol (According to SFM)

TP-30

TIL-15

15 µg  µg  

*Actinobacillus pleuropneumoniae *Pasteurella multocida

11

*M. haemolytica

14

Ticarcillin/ clavulanic acid

TIM-85

75/10 µg

*Enterobacteriaceae and Acinetobacter

20

*P. aeruginosa

24

Tobramycin   Tobramycin

TOB-10

10 µg

*Enterobacteriaceae *P. aeruginosa *Acinetobacter and Staphylococcus spp.  spp. 

Trimethoprim/ sulfamethoxazole

15

*Enterobacteriaceae *P. aeruginosa *Acinetobacter *Staphylococcus spp. *V. cholerae  cholerae 

Trimethoprim   Trimethoprim

S. aureus  ATCC 25923

30 µg

*Enterobacteriaceae *P. aeruginosa *Acinetobacter spp. *Staphylococcus spp. *Streptococcus spp. Tilmicosin (3) 

E. coli  ATCC 25922

5 µg

16

Page 12 12 /  / 16 16  

 

 

Interpretive Standards (mm)  (mm) 

 An ti mi micr cr ob ial Ag ent Code *Microorganism

Trip le Sulp hon amides

S3-300

Content Disk

(10)(6)

TUL-30

S

(Resistant)

(Intermediate)  

(Susceptible) 

15

*Enterococcus spp.

17

*S. pneumoniae and other Streptococcus spp.

---

---

>17

*for anaerobic (H. pylori)  organisms

MET-5

P. aerugi aerugi nosa  ATCC 27853 

---

---

---

---

18-24

---

---

18-24

---

---

17-21

---

>20

---

Metronidazole(8) 

S. aureus  ATCC 25923

>18

30 µg

*Staphylococcus spp.

E. coli  ATCC 25922

>17

30 µg 15

5 µg

Content Disk

20-31

>20

Interpretive Standards (mm)  An ti fu ng al A gen t

C. tropicalis  ATCC 750

>20

1 µg

20 µg

C. parapsilosis  ATCC 22019

21-29