assay_alumina and Magnesia Oral Suspension

Name:Mas,MylynL.

DateSubmitted:10/28/16

Pharm Chem 1! Se"ti#n: P$6

Date Per%#rmed: 11/0!/16

&'(eriment N#. ! C#m(le'#metry Assay of Alumina and Magnesia Oral Suspension for Aluminum Content ). D*+* *ND &S-L+S *. #lume/eihin Measurements Sam(le 1: *lumina and Manesia ral Sus(ensi#n #lume #% Sam(le St#"3 S#luti#n4: +rial 14 : 2!0.0 mL +rial 24 : 2!0.0 mL *li5u#t: +rial 14 : 10.0 mL +rial 24 : 10.0 mL lan34: 10.0 mL 7ater4 . +itrati#n Data

#lume #% +itrant -sed: VolumeReading

Trial1

Trial2

Blank(n/abased on

Initial Reading

0.00mL

0.00mL

USP) 2!.0!mL

Final Reading

2!.0!mL

2!.0!mL

!0.10mL

Total Volume Used

2!.0!mL

2!.0!mL

2.0!mL

#lumetri" S#luti#n -sed: Dis#dium &detate N%9 0.61; Pre(ared by: il#ria, L# #% *l$4 in Sam(le

Trial 2: 10!.8; > #% #% *l$4 in Sam(le

> De *""e(tan"e "riteria: 0.0 >?110.0>4 Sam(le: P#SS T* +FFICI#& R,UIR-.T )). D)SC-SS)N * sus(ensi#n #% *lumina and Manesia ral Sus(ensi#n Labelled Claim: 22! m/!mL4 7as assayed. Sam(le is "#m(#sed #% 7hite sus(ended (arti"les that needs t# be sha3en 7ell be%#re use. )t 7as st#red in a 7hite (lasti" "#ntainer that 7as tihtly "l#sed. +he sam(le 7as n#t %reshly (re(ared and 7as #(ened durin the 7ee3 #% the assay "t#ber 2?28, 20164. +7# titrati#n trials 7ere (er%#rmed %#r the assay #% *luminum $ydr#'ide "#ntent #% *lumina and Manesia ral Sus(ensi#n 7ith Dis#dium &detate S as the e'"ess titrant and 0.0! M =in" Sul%at e S as the ba"3 titran t. * 0.881 > de