3.NDC-Biochemistry-Week-03 (28-09-2014)

Narayana Dental PG Coaching - Week-03 Test (28-09-2014) Biochemistry (Enzymes, Vitamins & Miscellaneous) 1. The following is a group specific enzymes A. Pepsin B. Aminopeptidase C. Phospholipase D D. All of the above

9. Coenzymes are required in the following reactions A. Oxidation reduction B. Transamination C. Phosphorylation D. All of the above

2. The action of an enzyme is to A. Accelerate the rate of reaction B. Retard the rate of reaction C. Start the reaction D. All of the above 3.

10. Co enzyme Q is_________ A. Also called ubiquinone and benzoquinone B. Lipid soluble quinine with polyisoprenoid side chain C. Is a non-protein molecule D. All of the above

The following is a substrate specific enzymes A. Hexokinase B. Thiokinase C. Lactase D. Aminopeptidase

11. Which of the following is untrue about carbonic anhydrase? A. It is associated with haemoglobin in RBC B. It is never present in plasma C. It is also present in parietal cells of stomach ++ D. It contains Mg

4. The following is not a substrate specific enzyme A. Glucokinase B. Fructokinase C. Hexokinase D. Phosphofructokinase

12. Iron is present in all of the following except A. Myoglobin B. Cytochrome C. Catalase D. Pyruvate kinase

5. Chymotrypsin hydrolyses peptide bonds in which carboxyl group is contributed by A. Phenylalanine B. Tyrosine C. Tryptophan D. Any of the above 6. Coenyme responsible transfer is A. Acteyl co enzyme A B. Biotin C. THF4 D. Pyridoxine

for

single

13. Magnesium ions are cofactors for all the following except A. Hexokinase B. Pyruvate kinase C. PEP carboxykinase D. Lactate dehydrogenase

carbon

14. All the following are iron-containing enzymes except A. Carbonic anhydrase B. Catalase C. Peroxidase D. Cytochrome oxidase

7. Coenzymes combine with A. Proenzymes B. Apoenzymes C. Holoenzymes D. Antienzymes

15. Magnesium is needed for the activity of which enzyme A. Phosphatase B. Aldolase C. Dismutase D. ATPase

8. Enzyme + coenzyme constitutes A. Apoenzyme B. Proenzyme C. Prosoenzyme D. Holoenzyme

16. Which of the following is incorrect statement? A. Coenzymes frequently contain B vitamins as part of their structure

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Narayana Dental PG Coaching - Week-03 Test (28-09-2014) Biochemistry (Enzymes, Vitamins & Miscellaneous) B. Protein part of an enzyme is called as apoenzyme C. Holoenzyme is apoenzyme + coenzyme D. Noncompetitive inhibitor binds to the active site of the enzyme

D. Glutamate oxaloacetate transaminase 24. The cancer of prostate is best diagnosed by elevated blood level of _________ enzyme A. Alkaline phosphatase B. Lactate dehydrogenase C. Acid phosphatase D. Phosphor hexose isomerase

17. Allosteric inhibition is also known as A. Competitive inhibition B. Non-competitive inhibition C. Feedback inhibition D. None of the above

25. Creatine kinase is found in A. Myocardium B. Brain C. Muscles D. All of the above

18. An A. B. C.

allosteric enzyme Is generally present at the end of a pathway Generally catalyses a reversible reaction Generally catalyses the committed step unique to a pathway D. Possesses only substrate the

26. Wheat is an excellent source of which of the following vitamins A. Vit A B. Thiamin C. Riboflavin D. Vit C

19. Binding of the allosteric inhibitor to the allosteric enzyme is A. Covalent B. Reversible C. Energy consuming D. All of the above

27. Specific disease caused deficiency A. Pellagra B. Angular cheilitis C. Megaloblastic anaemia D. Peripheral polyneuritis

20. Kinetics of allosteric inhibition may be A. Competitive B. Non competitive C. Partially competitive D. Any of the above

by

vitamin

B1

28. Thiamine deficiency causes decreased energy production because A. It is required for the process of transamination B. It is co – factor in exudative reduction C. It is co - enzyme for transketolase in pentose phosphate pathway D. It is co – enzyme for pyruvate dehydrogenase

21. Following myocardial infarction, the earliest serum enzyme to rise is A. Creatinine kinase B. GOT C. GPT D. All of the above

29. Which of the following is a primary structure of flavoprotiens? A. Vit B6 B. Vit B2 C. Vit B1 D. Vit A

22. Which of the following enzyme persists longest in blood after a heart attack? A. GOT B. CPK C. LDH D. GPT

30. They yellow – green fluorescent urine is passed after ingesting multi – vitamin tablet. This is because of vitamin A. Thiamin B. Riboflavin C. Niacin D. Pyridoxine

23. The differential diagnosis of jaundice is possible by measuring blood level of the enzyme _________ A. Alkaline phosphatase B. Acid phosphatase C. Glutamate pyruvate transaminase

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Narayana Dental PG Coaching - Week-03 Test (28-09-2014) Biochemistry (Enzymes, Vitamins & Miscellaneous) 31. In hydrogen transfer reactions, riboflavin coenzyme accepts two hydrogen atoms at the positions ____ A. 1 and 10 B. 7 and 8 C. 5 and 6 D. 2 and 4

trans -sulfuration reaction A. Riboflavin B. Thiamine C. Pyridoxine D. Pantothenic acid 39. Peripheral neuropathy due to deficiency of vitamin is seen with A. Pyridoxine B. Vit E C. Vit A D. Pantothenic acid

32. Niacin deficiency is characterised by which of the following A. Dementia, dermatitis, diarrhoea B. Dermatitis, anaemia encephalopathy C. Diarrhoea, glossitas, neuritis D. Diarrhoea, encephalopathy anaemia

40. The antivitamin of pyrdoxine is A. Dicoumarol B. Avidin C. INH D. Aminopterin

33. People consuming only maize as staple diet develop niacin deficiency due to A. Low niacin B. Low tryptophan C. High leucine D. High isoleucine

41. Biotin deficiency is characterised by all of the following except A. Muscular pain B. Anaemia C. Nausea D. None of above

34. The amino acid from which niacin synthesized is A. Tyrosine B. Tryptophan C. Threonine D. Histidine 35. Vitamin used in homocystenuria is A. B1 B. B2 C. B6 D. B12

the

treatment

42. Consumption of raw egg white in the diet may result in the deficiency of A. Ribofla vin B. Biotin C. Thiamin D. Pyridoxine

of

43. Conenzyme A contains which of the following vitamins? A. Biotin B. Pyridoxine C. Pantothenic acid D. Niacin

36. Most of the body Vit B6 is present in which of the following enzymes? A. Liver phosphorylase B. Muscle phosphorylase C. Creatinine phospho kinase D. Glucose – 6 – phosphatase

44. Coenzyme A contains which of the following vitamins A. Biotin B. Pyridoxine C. Pantothenic acid D. Niacin

37. In vitamin B6 deficiency the abnormal metabolite which appears in urine is _________ A. Methyl malonic acid B. Formimino glutamic acid C. Xanthurenic acid D. None of the above

45. Vit B12 is absorbed from A. Stomach B. Duodenum C. Lower jejunum D. Terminal ileum

38. The following vitamin is important in nonoxidative decarboxylation, transamination and

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Narayana Dental PG Coaching - Week-03 Test (28-09-2014) Biochemistry (Enzymes, Vitamins & Miscellaneous) D. Vitamin K deficiency 46. Pernicious anaemia occurs in A. Vit B1 deficiency B. Vit B12 deficiency C. Vit C deficiency D. Vit D deficiency

54. Which of the following is no true of Vitamin D? A. Its active form is calcitriol B. Increased calcium absolption from the intestines C. Its deficiency reults in rickets D. Its decrease causes phophate reabsorption from the kidneys

47. The vitamin synthesized by intestinal bacteria is ______ A. Vitamin B12 B. Vitamin A C. Both D. None

55. Patients with severe renal diseases may not be able to tolerate the normal doses of which of the following vitamins? A. Vit A B. Vit B C. Vit C D. Vit D

48. Which of the following deficiencies causes scurvy? A. Vit A B. Vit B C. Vit C D. Vit D

56. Active form of Vitamin D in kidney is A. 1 dihydroxy chole calciferol B. 25 hydroxy chole calciferol C. 1, 25 dihydroxy chole calciferol D. 7 dihydroxy chole calciferol

49. Cereals are deficient in A. Vitamin C B. Vitamin B – Complex C. Iron D. Calcium

57. The dificiency of which newborn? A. Vit C B. Vit D C. Vit E D. Vit K

50. Vitamin C is present in largest amount in the body in A. Eye B. Kidneys C. Testes D. Adrenal cortex

is not know in

58. Biological activity of tocopherols has been atributed in part to their action as A. Antioxidant B. Anticoagulants C. Provitamin D. Antidotes for selenium poisoning

51. Which of the following dental tissues is most likely to be effected by Vit - A deficiency? A. Enamel B. Dentin C. Cementum D. Pulp

59. Tocopherol is associated with A. Vitamin K B. Vitamin E C. Vitamin A D. Vitamin D

52. Deficiency of vitamin A causes the following EXCEPT A. Night blindness B. Corneal dryness C. Bitot’s spots D. Myopia

60. Vitamin k deficiency is indicated by A. Low platelet count B. Increased PTT C. Decreased PTT D. None of the above

53. Xerophthalmia is caused by A. Vitamin A deficiency B. Vitamin D deficiency C. Vitamin C deficiency

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Narayana Dental PG Coaching - Week-03 Test (28-09-2014) Biochemistry (Enzymes, Vitamins & Miscellaneous) ANSWERS Q. No

Ans

1 2 3 4 5 6

D A C C D C

7 8 9 10 11 12

B D D D D D

13 14 15 16 17 18

D A D D C C

19 20 21 22 23 24

B D A C A C

25 26 27 28 29 30

D B D D B B

31 32 33 34 35 36

A A A B C B

37 38 39 40 41 42

C C A C D B

43

C

5

44 45 46 47

C D B A

48 49 50 51 52 53

C A D A D A

54 55 56 57 58 59

D D C C A B

60

B