3 Leucopoyesis Resumen

March 11, 2023 | Author: Anonymous | Category: N/A
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Aiuhkpkyisns Is ia prkhis prkhisk k g trg trgvî vîss bia huga si ckrjge ckrjge euivks euivks oaødu oaøduaks aks dagehks dagehks k aiuhkh aiuhkhntk ntks, s, yg sige sige orgeua orgeuakhn khntks tks k gorgeuakhntks. Prkhisk ie oieirga y hgrghtirêstnhgs risgatgetis 

Isti prkhisk pgrti, hkjk tkbgs ags hîauags sgeouêeigs, bi ag hîauag jgbri mijgtkpkyîtnhg paurnpktiehnga. Auiok khurrie ags prnjirgs cgsis bi bnciriehnghnøe y bnvnsnøe bi ag hîauag prihurskrg mijgtkpkyîtnhg juatnpktiehnga ie ak akss bnciri bncirieti etiss tnp tnpks ks bi hîauag hîauagss prk prkoie oientk ntkrgs rgs uenpkt uenpktieh iehnga ngais, is, qui auiok auiok bi vgrnk vgrnkss pgsks, pgsks, si bncir bncirieh iehnge nge ie hîa hîauag uagss hkjprkjitnbgs. Luetk g gquiaags hîauags hkjprkjitnbgs ie ag ckrjghnøe bi irntrkhntks, si ckrjge bks aêeigs prnehnpgais bi aiuhkhntks, ags aêeigs jniaknbi j niaknbi y anecknbi<  Aêeig jniaknbi< si bnciriehng bnciriehng ie hîauags prihurskrgs (jniakdagstks), (jniakdagstks), aks hugais bgrçe auogr auogr g aks oaøduaks  dagehks bi tnpk orgeuakhntks. orgeuakhntks. Ktrgs hîauags prihurskrgs ske aks jkekdagstks, jkekdagstks, qui bge auogr auogr g aks jkekhntks.

Aêeig anecknbi< Xi bnciriehng ie hîauags prihurskrgs biekjnegbgs aneckdagstks, aks hugais bgrçe auogr g aks aneckhntks D y R. 



Aks orgeuakhntks y jkekhntks si ckrjge søak ie ia tilnbk jniaknbi bi ag jîbuag øsig6 aks aneckhntks y hîauags  pagsjçtnhgs si prkbuhie skdri tkbk ie aks bncirietis ørogeks anecøoieks, anecøoieks, ie ispihnga ie aks ogeoanks anecçtnhks, ia dgzk, ia tnjk, ags gjêobgags gjêobgags y vgrngs dkasgs bi ti tilnbk lnbk anecçtnhk ie ktrgs pgrtis ia huirpk, huirpk, hkjk ie ag jîbuag øsig y ags ags paghgs bi Piyir sntugbgs bidglk bia ipntiank bi ag pgrib netistnega. 

Aks aiuhkhntks ckrjgbks ie ag jîbuag øsig si gajghiege bietrk bi ag jnsjg mgstg qui ske eihisgrnks ie ia snstijg hnrhuagtkrnk. Hugebk suroi ag eihisnbgb, cghtkris istnjuagetis ievêge ievêge ag si÷ga pgrg su andirghnøe. Mgy 8 vihis jçs aiuhkhntks gajghiegbks qui aks qui hnrhuage pkr tkbg ag sgeori. Aks aneckhntks aneckhntks si gajghiege gajghiege ie aks ogeoanks ogeoanks ane anecçtnhk cçtnhks, s, ixhiptk ixhiptk ue piqui÷k piqui÷k eüjirk qui si trgespkrtg trgespkrtg  tijpkrgajieti ie ag sgeori. Bipiebniebk bia tnpk bi oaøduak dagehk g ckrjgr, ag aiuhkpkyisns si bnvnbi ie 4 prkhisks< Ag orgeuakhntkpkyisns (ckrjghnøe bi orgeuakhntks)y ag ckrjghnøe bi gorgeuakhntks hkeckrjgbk pkr ag jkekhntkpkyisns y aneckpkyisns. Orgeuakhntkpkyisns< Is ia prkhisk qui pirjnti ag oieirghnøe bi aks orgeuakhntks pkanjkrckeuhaigris orgeuakhntks pkanjkrckeuhaigris bi ag sgeori. Isti prkhisk si oieirg g pgrtnr bi ag aêeig jniaknbi y si bishrndi bi ag snounieti ckrjg< 

Aks 8 tnpks bi orgeuakhntks (dgskcnaks, iksnekcnaks, y eiutrkcnaks), birnvge bi su prkpng hîauag jgbri uenpktiehngais k dnpktiehngais, dnpktiehngais, hgbg ueg ueg bi istgs hîauags jgbris bishniebi bi ag YCH-X (Yenbgb ckrjgbkrg bi hkakengs jniakbis) k YCH- OIJJ (uenbgb ckrjgbkrg bi hkakengs bi orgeuakhntks, irntrkhntk irntrkhntks, s, jghrøcgoks y jioghgrnkhntks ), ag huga, nebuhnbg  pkr hntksnegs hkjk ag OJ-HXC(cghtkr istnjuageti bi hkakengs bi orgeuakhntks y jkekhntks) , ag NA-8 y ag NA-9 , puibi bnciriehn bnci riehngrsi grsi ie YCH-Ik YCH-Ik pgrg aks iksneøcnaks iksneøcnaks y YCH-Dg, YCH-Dg, pgrg aks dgsøcnaks( dgsøcnaks(nebu nebuhnbg hnbg pkr ag cgatg NA-9), NA-9), gjdgs sucrie bnvnsnøe hiauagr pgrg bgr krnoie g ag hîauag prihurskrg k jniakdagstk (sniebk ia prnjir istgbnk ie su bnciriehnghnøe). Pgrg aks eiutrøcnaks, ag ag hîauag jniaknbi juatnpktiehnga juatnpktiehnga (YCH-OIJJ) (YCH-OIJJ) is nebuhnbg g bnciriehngrsi ie ueg hîauag jgbri dnpktiehnga< YCH-OJ (Yenbgb ckrjgbkrg bi orgeuakhntks ‘eiutrøcnaks- y bi jkekhntks), pkr hntksne gs hkjk ia OJ-HXC, OJ-HX C, ia cghtkr istnjuageti istnjuageti bi hkak hkakengs engs orgeuakhntk orgeuakhntkss (O-H (O-HXC) XC) y ag NA-8, huyg jntksns prkbuhi bks hîauags jgbris uenpktiehngais uenpktiehnga is < ag YCH-O pgrg aks eiutrøcnaks eiutrøcnaks y ag YCH-J pgrg aks aks jkekhntks, sniebk nebuhnbk nebuhnbk pkr hntkhnegs hntkhnegs hkjk ia OJ-HXC, O-HXC y ag NA-8. Ie ckrjg snjnagr g ags YCH-Dg y YCH-Ik, si bnvnbi y ckrjg jniakdagstks. Aks jniakdagstks, ske prihurskris bi aks 8 tnpks bi orgeuakhntks, y ek mgy ckrjg bi bnciriehngraks ietri sê, ek si sgdi sn ue jniakdagstk gnsagbk puibi prkbuhnr aks 8 orgeuakhntks k sn mgy uek ispihêcnhk pgrg hgbg uek, istks si bnvnbie  pkr jntksns y si bnciriehnge ie aks prkjniakhntks, prkjniakhntks, qui oieirg ags orgeuaghnkeis gzurøcnags prnjgrngs bi aks  pkanjkrckeuhaigris  pkanjkrckeuhaigr is y, isti g su viz si bnvnbi pgrg ckrjgr jniakhntks qui oieirg orgeuaghnkeis sihuebgrngs k ispihêcnhgs. Ie ag itgpg bi jniakhntk is qui si puibie bnciriehngr bnciriehngr aks 8 tnpks bi orgeuakhntks (eiutrøcnak, (eiutrøcnak, dgsøcnak y iksneøcnak) yg qui si bnstneouie aks orçeuaks sihuebgrnks ispihêcnhks bi hgbg uek.

 

Ie ia hgsk bi aks eiutrøcnaks, aks jniakhntks si bnciriehng ie jitgjniakhntk eiutrøcnak, auiok ie jitgjniakhntk eiutrøcnak lkvie, jitgjniakhntk eiutrøcnak hgygbk y pkr üatnjk ie eiutrøcnak pkaanjkrckeuhaigr. Pkr ktrk agbk, ia jniakhntk iksneøcnak, si bnciriehng ie jitgjniakhntk iksneøcnak y pkstirnkrjieti ie ia iksneøcnak pkanjkrckeuhaigr. Pkr üatnjk, ia jniakhntk dgsøcnak, si bnciriehng y ckrjg ia dgsøcnak pkanjkrckeuhaigr. pkanjkrckeuhaigr. Tihndie ag necauiehng bi ags hntkhnegs hkjk ag NA-7, NA-3, REC-η (cghtkr bi eihrksns tujkrga gacg) y NA-9. Jkekhntk Jkekh ntkpky pkyisn isns6 s6 is ag ckrjgh ckrjghnke nke bi jke jkekh khntk ntkss g pgrtnr pgrtnr bi YCH-J YCH-J (Yenbg (Yenbgb b Ckrjgb Ckrjgbkrg krg bi Hkaken Hkakengg Jkekhntnhgs) 

Ag hiauag jgbri paurnpktiehnga prkbuhi 4 tnpks jgs bi hiauags jgbri (Jniaknbis y anecknbis) Gaouegs hiauags jniaknbis si bnciriehng ie hiauags prkoientkrgs, y ie ia hgsk bi ktrgs hiauags jniaknbis y anecgtnhgs pgsge bnrihtgjieti g hiauags prihurskrgs. Ag hiauag prkoientkrgs ek ske hgpghis bi riprkbuhnrsi y istge hkjprkjitnbgs g bgr krnoie g iaijietks bi ag sgeori jgs ispihncnhks. Ag snounieti oieirghnke ske ags hiauags prihurskrgs (dagstks) 

Jkekdagstks< 7ir prihurskr jkekhntkpkyitnhk bnciriehngdai jkrckakonhgjieti. jkrckakonhgjieti. Is ueg hiauag orgebi, hke ue

bngjitrk bi 79-44j, huietg hke ue orge euhaik y hke mgstg 3 euhaikaks. 

Prkjkekhntk< Pksii ue bngjitrk bi 72-40 j, pirjnti vnsuganzgr 7-4 euihaikaks.



Jkekhntk< Bngjitrk bi 72-40 j, ia eühaik tniei ckrjg bi mirrgburg.

Jghrkcgok< Hkeaaivg hgjdnks jkrckakonhks sioüe ia tilnbks ie ia qui si riqunirg< Mnstkhntks(pnia), Mnstkhntks(pnia), Ogeoanks anecgtnhks, Gaikagris puajkegris, puajkegris, Hiauags bi Fupccir (mnogbk), ie ia dgzk y jibuag ksig. 

Tiouaghnøe bi ag jkekhntkpkyisns jkekhntkpkyisns Netiraiuquneg 8< Cghtkr istnjuageti bi ags hkakeng paurnpktiehngais, prkjuivi ag prkancirghnke bi ags hîauags mijgtkpkyitnhgs. Cghtkr istnjuageti bi hkakengs orgeuak-jkekhntnhgs (OJ-HXC)< Netirvniei ie ag prkancirghnke y jgburghnke bi ags tktganbgb bi aks iaijietks Xgeouneiks Cghtkr istnjuageti bi hkakengs jkekhntnhgs< Nebuhi ag istnjuaghnøe bi hkakengs bi hiauags prkoientkrgs bi ag aêeig jkekhntkpkyitnh jkekhntkpkyitnhgg Aneckhntkpkyisns< Ckrjghnøe bi aneckhntks. Aneckhntkpkyisns< Hkjniezg bisbi ueg hiauag jgbri mijgtkpkyitnhg paurnpktiehnga orghngs g ag ghhnøe bi Netiraiuqunegs< Netiraiuquneg 8, mghi qui ag hiauag jgbri si ispihnganhi ie tilnbk anecknbi Netiraiuquneg 2, Istg riaghnkegbg hke ag prkancirghnke bi aks aneckhntks D y R. Ags hiauags jgbris anecknbis ijpnizge su bisgrrkaak ie ag jibuag, pirk ak hkjpaitge ie aks tilnbks anecgtnhks ie ispihnga aks ogeoanks anecgtnhks, ia dgzk, ia tnjk, ags gjnogbgags… Istgs hiauags bi bnciriehng ijpnizg bnciriehngebksi ie < 



Aneckdagstk< Euhaik orgebi, ribkebigbk, hke ue euhaikak.



Prkaneckhntk< Jgs piqui÷k

Aneckhntks< Ietri istks tieijks Aneckhntks D (ckrjge getnhuirpks)< Rirjneg su jgburghnøe ie ia dgzk, Ie ag jntgb bi ag vnbg citga is   prkhisgbg pkr ia mnogbk mnogbk y bispuis bia eghn eghnjnietk jnietk pkr ag jibuag. Aks aneckhntks D trgs bnvnbnrsi gprkx. Yeks 9 bngs, hugebk istge jgburks, bi puibie bnciriehngr ie aneckehntks D hke jijkrng k dnie ie hiauags pagsjgtnhgs orghngs g ag istnjuaghnke bia aneckhntk R HB2. Aneckhntks R (Tispkesgdais bi ag nejuenbgb hiauagr)< Xi krnonege ie ag jibuag y jnorge ga Rnjk bkebi si  bnvnbie y bisgrrkaage ueg ispihncnhnbgb crieti g ktrk getnoiek. Ag hiauag nejgburg (tnjkhntk) burgeti ia prkhisk bi jgburghnøe ie ia tnjk si bnciriehng ie aneckhntk R hkkpirgbkr  (HB2), isti istgdaihi y jgxnjnzg ags hgpghnbgbis bi biciesg bia snstijg nejuentgrnk, k ie aneckhntkR hntktkxnhk (HB=), isti eiutrganzg ags hiauags necihtgbgs pkr jnhrkkrogensjk netirhiauagris. Aks aneckhntks bisgrrkaagbk hnrhuage ie ag sgeori y ia snstijg anecgtnhk mgstg qui ske ghtnvgbks ga hketghtgr hke ue getnoiek ispihncnhk ia huga netirghtug hke ia rihiptkr bia aneckhntk R qui mgy ie su supircnhni. Istks getnoieks bidie sir prisietgbk g aks aneckhntks R pkr hiauags prisietgbkrgs bi 

 

getnoieks, hkjk ags biebrntnhgs k aks jghrkcgoks jibngeti jkaihuags bi hkjpailk jgykr bi mnstkhkjpgtndnanbgb. Bi isti jkbk aks aneckhntks R puibi rispkebir ie ckrjg ispihncnhg hketrg pgtkoieks y hiauags tujkrgais. Hnhak vntga bi aiuhkhntks< Ag vnbg bi aks orgeuakhntk bispuis bi qui sgaie bi ag jibuag ksig is ekrjgajieti bi 2-= mkrgs ie ag sgeori bispuis 2-9 bngs ie ia tilnbk riquirnbk Jkekhntks< 70-40mkrgs ie sgeori, getis bi pgsgr g trgvis bi ags jijdrgegs hgpnagris mghng aks tilnbks. Yeg viz ie aks tilnbks gujietge gujietge su tgjg÷k tgjg÷k mgstg hkevirtnrs hkevirtnrsii ie jghrkcgoks jghrkcgoks tnruagris tnruagris y puibie puibie vnvnr jisis g ek sir qui si bistruyge ga riganzgr su cuehnøe cgokhntnhg Aks aneckhntks ietrge ie ia snstijg hnrhuagtkrnk hketneugjieti luetk ga briegli bi ag anecg prkhibietis bi aks ogeoanks anecgtnhks y ktrks tilnbks anecgtnhks. Rrgs uegs mkrgs sgaie bi ag sgeori mghng aks tilnbks jibngetis bngpibisns, bispuis vuiavie g ietrgr ie ag anecg y ritkrege g ag sgeori y gsn mgy ueg hketneug hnrhuaghnøe bi aneckhntks pkr ia krogensjk. Aks aneckhntks tnieie ueg vnbg bi sijgegs k jisis, su burghnøe bipiebi bi ag eihisnbgb bia krogensjk bi istgs hiauags. Aks aiuh aiuhkhnt khntks ks  (oaødu (oaøduaks aks dagehks dagehks)) ske ue hkelue hkeluetk tk bi hîauags  hîauags  sgeouêeigs  sgeouêeigs  qui ske ilihu ilihutk tkrgs rgs bi ag rispuistg nejuentgrng.. Xi krnonege ie ag jîbuag øsig nejuentgrng øsig y  y ie ia tilnbk anecçtnhk. anecçtnhk.

Ia rihuietk ekrjga bi oaøduaks dagehks cauhtüg ietri 2 y 77 x 70 >/A, y suiai ixprisgrsi hkjk 2000-77 000 oaøduaks dagehks pkr jnhrkantrk. Hkeckrjge, gprkxnjgbgjieti, ia 7% bia vkaujie sgeouêeik tktga. Hgrghtirêstnhgs<

ske hîauags orgebis i nehkakrgs y tnieie  ckrjg iscîrnhg. 

ske jçs orgebis qui aks mijgtêis (oaøduaks (oaøduaks rklks), rklks), pirk ag hgetnbgb bi iaaks ie ag sgeori is juhmk jiekr.

 

Xke ags üenhgs hîauags hkjpaitgs bi ag sgeori, is bihnr qui hketnieie eühaik y kroçeuaks. Aks oaøduaks oaøduaks dagehk dagehks, s, ske hgpgh hgpghis is bi sganr sganr y ietrgr ietrgr ie aks vgsks sgeou sgeouêei êeiks ks,, ie ue prk prkhis hisk k aag aagjgb jgbk k

bngpîbisns.  

 Ekrjgajieti, mgy garibibkr bi 3.000 3.000 g 70.000 oaøduaks dagehks pkr jj8 bi sgeori.

Ie ags iecirjibgbis necihhnksgs, hkjk ag eiujkeêg y ag jieneontns, ag hgetnbgb bi oaøduaks dagehks ie ag sgeori suiai gujietgr (aiuhkhntksns) (aiuhkhntksns)..  

Ie hnirtgs necihhnkeis vnrgais, hkjk ia sgrgjpnøe, ag hgetnbgb bi oaøduaks dagehks ie ag sgeori puibi bnsjneunr (aiuhkpieng).  

Rnpks bi Aiuhkhntks< Orgeuagbks< Eiutrøcnaks
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