2.NDC-Biochemistry-Week-02 (21-09-2014)

Narayana Dental PG Coaching - Week-02 Test (21-09-2014) Biochemistry (Carbohydrates, Proteins & Lipids) 1. Glycolysis occurs in A. Cytoplasm B. Mitochondrion C. Both in cytoplasm and mitochondria D. Only in presence of O2

C. Muscle and liver D. None of the above 9. Which of the following enzyme is not involved in gluconeogenesis? A. Pyruvate carboxylase B. Phosphoenol pyruvate C. Carboxy kinase D. Hexokinase

2. The oxidation of glucose or glycogen to pyruvate and lactate by EMF pathway is called as A. Glycolysis B. Glycogeneis C. Glycogenlysis D. The hexose monophosphate shunt

10. Which of the following compound is not a substrate for gluconeogenesis pathway? A. Glycerol B. Lactate C. Oxaloacetate D. Glycogen

3. All these reactions take place inside the mitochondria except A. EMF pathway B. Kreby cycle C. Urea cycle D. Electron transfer

11. The key enzymes of gluconeogenesis is A. Pyruvate carboxylase B. Fructose 1,6 diphosphatase C. Glucose 6 phosphatase D. Phosphonol pyruvate carboxykinase

4. The enzyme involved in the first committed step of glycolysis is A. Phosphofructokinase B. Glucose – 6 – phosphatase C. Hexokinase D. Enolase

12. Enzymes concerned with the citric acid cycle are found in the A. Nucleus B. Ribosomes C. Mitochondria D. Non particular cytoplasm

5. All of the following are present in pyruvate dehydrogenase complex except A. NAD B. FAD C. TPP D. GDP

13. Kreb’s cycle occurs in _______ condition A. Aerobic B. Anaerobic C. Microaerophilic D. Aerobic and anaerobic.

6. Which of them is multienzyme complex. A. Pyruvate dehydrogenase B. Alpha ketoglutarate dehydrogenase C. Succinate dehydrogenase D. Enolase

14. Krebs cycle operates in A. Aerobic conditions only B. Anaerobic conditions only C. Aerobic and anaerobic conditions D. Microaerophilic conditions

7. Pyruvate dehydrogenase complex contains all except A. Biotin B. NAD C. FAD D. Co-A

15. How may ATP molecules are produced in the citric acid cycle itself? A. One B. Two C. Twelve D. Fifteen

8. Gluconeogenesis mainly occurs in which of the following organs. A. Liver and kidney B. Kidney and heart

16. Which of the following statement is not true for HMP shunt pathway? A. CO2 is not produced in it

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Narayana Dental PG Coaching - Week-02 Test (21-09-2014) Biochemistry (Carbohydrates, Proteins & Lipids) 24. The committed step in the synthesis of pyrimidine nucelotide is A. Formation of UMP B. Formation of dihydro-orotic acid C. Formation of N-carbomoyl asparatic acid D. Formation of arotic decarboxylase.

B. NADPH is produced C. Pentoses are produced D. Does not produce ATP 17. Sites where HMP shunts can occur include A. liver B. WBC C. Lactating mammary glands D. Testes E. All

25. Fatty acid oxidation occurs in A. Cytoplasm B. Microsomes C. Mitochondria D. All of the Above

18. Step in HMP pathway requiring TPP A. G6 PD B. 6 phosphogluconat dehydrogenase C. Transketolase D. Transaldotase

26. Which of the following fatty acids are not synthesised in human body? A. Oleic, linoleic and linolenic acid B. Arachidonic, linolenic and linoleic acid C. Palmitic, oleic and arachidonic D. Linoleic, arachidonic and stearic acid

19. In the mitochondria, urea cycle is integrated to A. Electron transport chain B. Oxidative phosphorylation C. Oxidation of fatty acids D. TCA cycle

27. A fatty acid that is not synthesized in man is A. Linoleic acid B. Oleic acid C. Palmitic acid D. Stearic acid

20. Urea has two nitrogen atoms; the first comes from ammonia; which compound is the source of second nitrogen atom A. Aspartate B. Glutamate C. Citrulline D. Ornithine

28. The lipoprotein particles that have the highest percentage concentration of cholestrol is A. Chylomicron B. VLDL (very low density lipoprotein) C. LDL (low density lipoprotein) D. HDL(high density lipoprotein)

21. Name the bye – product of the urea cycle A. Aspartate B. Ammonia C. Ornithine D. Fumarate

29. The most important role of cholesterol is A. It is a component of cell membrane B. It is a precursor of polyunsaturated fatty acids C. A stores up energy D. None of the above

22. Which of the following substance is a key substance in the manufature of both purines and pyrimidine? A. Carbomyl phosphate B. Adenosyl metheonine C. Phosphoriboxyl pyrophosphate D. None of the above

30. β - oxidation of old - chain fatty acids produce A. Succinyl CoA B. Propionyl CoA C. Acetyl CoA D. Malonly CoA

23. Carbamoyl phosphate is required for the synthesis of A. Pyrimidines B. Purines C. ATP D. RNA

31. The total blood concentration of ketone bodies in well fed individual is A. 1 mg % B. 5 mg % C. 12 mg % D. 20 mg %

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Narayana Dental PG Coaching - Week-02 Test (21-09-2014) Biochemistry (Carbohydrates, Proteins & Lipids) D. Cephalin 32. The humarn plasma lipoprotein containing the highest percentage of tricacylglycerol by weight is A. VLDL B. Chylomicrons C. HDL D. LDL

40. Which of the following is lost from white matter in multiple sclerosis? A. Phospholipids B. Sphingolipids C. Both of the above D. None of the above

33. High content of cholesterol is present in A. Coconut oil B. Egg yolk C. Hydrogenated fat D. Ghee (unsaturated)

41. Which of the following fatty acid is not an essential fatty acid? A. Linoleic acid B. Linolenic acid C. Arachidonic acid D. Palmitic acid

34. Fatty acids help in synthesis of all except A. Glucose B. Cholesterol C. Ketone bodies D. Fat

42. The essential fatty acid is A. Linoleic acid B. Palnoific acid C. Stearic acid D. Oleaic acid

35. Insulin caused lipogenesis by all except A. Increasing acetyl CoA corboxylase activity B. Increasing the transport of glucose in to the cells C. Inhibits pyruvate dehydrogenase D. Decreases intracellular cAMP level

43. The measure of degree of unsaturation of a fat is A. Saponification number B. Iodine number C. Acid number D. None of the above

36. Lipid is required in the average diet because it A. Has a high caloric value B. Provides essential fatty acids C. Acids in absorption of carbohydrates D. Is necessary for storage of carbohydrates

44. The fat which is esterifies with alcohol of high molecular weight are known as A. Simple fats B. Oils C. Waxes D. Triglycerides

37. The main pathway for “De-Novo” synthesis of fatty acids occurs in A. Mitochondria B. Nucleus C. Cytosol D. None of the above 38. The reducing equivalent for synthesis is derived from A. Glycolysis B. Kreb’s cycle C. Urea cycle D. Pentose phosphate pathway

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45. The lipoproteins rich in cholesterol are A. HDL B. VLDL C. LDL D. Chylomicron

acid 46. Fats absorbed with the help of bile salts are A. Free fatty acids B. Glycerol C. Higher fatty acids, diglycerides and monoglycerides D. All of the above

39. The following is not a phospholipid A. Sphingomyelin B. Lecithin C. Cerebroside

47. Site of β-oxidation of fatty acid is A. Cytoplasm B. Mitochondria

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Narayana Dental PG Coaching - Week-02 Test (21-09-2014) Biochemistry (Carbohydrates, Proteins & Lipids) C. Both cytoplasm and mitochondria D. Lysosomes 48. α – oxidation is important in catabolism of A. All fatty acids B. Branched chain and odd chain fatty acids C. Fatty acids in brain D. B + C 49. Increased cholesterol level in blood is found A. Diabetes mellitus B. Nephrotic syndrome C. Obstructive jaundice D. All of the above 50. The ratio of HDL – cholesterol which is considered average risk for coronary artery disease is A. 51 for G and 4.51 for E B. 9.51 for G and 71 for E C. 21 for G and 1.5 1E D. None of the above

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Narayana Dental PG Coaching - Week-02 Test (21-09-2014) Biochemistry (Carbohydrates, Proteins & Lipids) ANSWERS

30

B

Q. No

Ans

31

A

1

A

32

B

2

A

33

B

3

A

34

A

4

C

35

C

5

D

36

B

6

A

37

C

7

A

38

D

8

A

39

C

9

D

40

C

10

D

41

D

11

A

42

A

12

C

43

B

13

A

44

C

14

A

45

C

15

C

46

C

16

A

47

B

17

E

48

D

18

C

49

D

19

D

50

A

20

A

21

D

22

C

23

A

24

C

25

D

26

B

27

A

28

C

29

A

5