24b_VIRUS H1N1, HOW TO WIN_EG

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Novel of NON DEEP REALITY – FANTASY PRODUCT With lots of love dedicated, to my parents, to EL_lines in Natalia, Olga, Onder, and of course to my colleagues By Price LIAPIS Panagiotis With lots of love dedicated, to my parents, to EL_lines in Natalia, Olga, Onder, and of course to my partners By Price LIAPIS Panagiotis При большом количестве посвященный, любви мои родители Греки, В Наталья, Οльга, и Ондер, к моим коллегам По цене LIAPIS Panagiotis

Συγγραφέας ΛΙΑΠΗΣ ΠΑΝΑΓΙΩΤΗΣ Τίτλος Δ/νση Κ.Βάρναλη 12, 15121 Πεύκη, Αθήνα Τηλ. 210-6149149 Κιν. 6937097443 Ε-mail [email protected] ΔΙΑΘΕΣΗ 210.8065618 6937097443 Author LIAPIS Panagiotis Title Addr K. Varnali 12 15121 Pine Athens Tel 210-6149149 Mob. 6937097443

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A few words from the author My Friends in this textbook, take the knowledge that until now store it in dusty Greek manuscripts of Plato, Aristotle and other ancient fotodoton in damp basements monasteries and private libraries disekatomyriouchon. We revealed through masterfully blended events of economy, religion, Greek history and mythology, the confirmations of Medicine and the multidimensional social structures, the Greek discovery of ether for which spoke Platonas and Aristotle, the mineral krystalyka and electrical properties, their initiatory secret caves, history, radiation and their effects on human health, MIND CONTROL is the technical control of the mind legends and myths, travel guides, the history of Russia and Mongolia, Dynasty RURIC, the Greek supremacy, The Secret of the Living Water, forecasts in recent days, the establishment of the 4th Reich, well read, and its organization, methods of prevalence of the 4th Reich, Geostrategic, The Secrets of the Parthenon, The stolen works of art, naturally leads business survival in difficult times. There are missing from my literary work of literature, prayer and research on photovoltaic technology in whose threshold of energy is free. Also presented a series of investigations on a series of error events for the signs, and possible manipulation of cosmogony, incidents involving the Nazis and the possible bases in space, President Obama, and the new doctrine Panthriskeias launched in conjunction with the Worship infernal beings are a new mirror through which can be seen the current scene of the enormous progress in the areas of MIND CONTROL, the chip EMV of Bill Gates on bank credit cards, the emerging banking system in relation to economic crashes of America The SIONISMOS and the New World Order of the 4th Reich, and PEOPLE CLONES - Men in Black, and the CIA in connection with the anti-government slogans and reactive walls define a new reality, which leads to control police forces in Use of Sound for centuries hidden weapons ancient Greeks developed from the Greek National Nuclear epistimoina C. Gkiolva. The creations of the Plan "Arrow" (sound rule) and the sound "Artemis", as are sources on the web are presented in detail below in relation to biological warfare aircraft from the US-spray from chemical and microbial air over cities. Trying to minimize the harmful effects that using genetics Industry, extensive fires, building new towns in the concentration camps of D Reich, apply geostrategic implementation plan new war in the Balkans because of Kosovo, where the project "Blue Ray" at the upcoming mayhem by the end of 01/2010 will chrisimopoiithoun

new weapons bass Police with physical effects of radiation on the human organism KARKINOUS By Price LIAPIS Panagiotis

CAUTION - SIGNIFICANT MARKINGS TO READER 1. This project is a bottomless MYTHISTORIMA Reality 2. Clarifies Developed Fiction 3. Any resemblance to actual persons, locations and events are imaginary, purely accidental, not existing in the present reality and past it. 4. Copyrights on works protected by the current constitution, laws and jurisprudence 5. Prohibited the reproduction and distribution of all or part of the document without the prior written permission of the author and an award identifying figures and in words of the author's remuneration, rights and remuneration of the Greek state, the duration of the contract and the parties. 6. The document bears a registered trademark 7. The project is only available for private use, prohibited the reading public all or part of it. 8. The work donate to the library of the Greek state request and complied with the legislation providing for the process. 9. For Greek citizens: To book not sold through bookstores and other retail outlets. KNOWLEDGE donors. 10. The book takes seeker typing costs and expenses of this mission. 11. The Writer LIAPIS Panagiotis receive no remuneration (money) making a work available 12. The book has no subversive of the system concept, but instead Net conglomerate of all the Greeks of Planet Earth, 120,000,000 Greeks to create well-governed society as defined by the democratic, elected Parliamentary Antiptosopous People (primary form of power) 13. The GREECE Fri all the problems exist because of the scandalous EVNNOIA OF MARY. The Greeks GYIOS DEFKALIONOS OF, THE LIGHT, AS NO ONE GREEK even no hope, no justice. Amen. Copyright by Panagioti Liapi THE BOOK IS NOT FOR SALE I GIVE THE KNOWLEDGE FREE – NO COST AT THE BEGINNING ON EARTH FROM TITHIS WAS ONLY TWO AUTHENTIC RACES, GREEKS and DRACONIANS. GREEKS HAVE THE MARK OF SUNNY SOUL IN THE EYES DRACONIANS HAVE THE MARK OF KNIFE IN THE BACK BUT ONLY THE MEMBERS OF THE CIRCLE KNOWS THAT. (From Dialogues of Diomidis with Alexander the Great )

PARADOCHES 1. Pharmaceutical products containing mercury, lead, uranium, plutonium, etc. is ANOUMINIO oxymoron and walks contrary. 2. PRESERVATIVES - amplifiers which are carcinogens and help the brain is deadly 3. PARASKEFASMATAIOURGOUN Instability in the immune system are weapons of biological warfare EVEN IF THE WORLD Galactic H GROUP SAYS HEALTH AND ENDORSES the opposite! http://articles.mercola.com/sites/articles/archive/20 / 01/03/07/vaccine-ingredients.aspx 1. In the influenza vaccine contains formaldehyde. Read on syneseia fatal symptoms Formaldehyde - "disinfectant and preservative, is known to cause cancer, chronic bronchitis, eye irritation when exposed to the immune system Autism now occurs at a frequency of 1 in 67. While the period before the vaccine was 1 in 20,000. 2. ALUMINIUM (two versions) - are directly mein nosoAltschaimer 2) Divine ammonia-mineral fertilizer. Known to cause kidney damage and liver, and gastrointestinal disorders 3. AMFOTERINI B - antifungal disinfectant, causing damage to the urinary tract, intestines and heart functions 4) ANAKYKLOMENOS ZOIKOS WEB (multiple) - a component of mad cow disease 4. MSG - known to cause cancer in humans 5. FAINOLES - highly toxic disinfectant dye, causing damage to the liver, kidney, heart and respiratory FAINOAINOXYAITHANOLI 'antifreeze' - proven neurotoxic effects echounakraies 6. THYMEROSAL (Mercury) - Toxikotato, on reasonable grounds that it causes autism in children and many related behavioral disturbances associated with it. They also include the following animal tissues: pig blood, horse blood, rabbit brain, kidney dog, monkey kidneys, chicken embryos, calf serum, fetal calf serum, etc. Malista gentlemen, I see something crazy chickens and cows, sheep, goats, and be crazy pig and rabbit, many animals that we eat. There and crazy centipede or logikeftikane all;;; My friend Father seen here crazy horses and centaurs, crazy chickens and flying vampires, only nefelim mermaid sees, but let them do the mermaids we its cool as always ... the issue was again one that we are coming from the next book .... . To 2001,

o Jock Doubleday, director of three nonprofit corporation Natural Health California offers financial reward to anyone who is a doctor or pharmaceutical company executive publicly drink a mixture containing the above carriers (not included the main ingredients, dead or alive, or viruses bacteria) in the same proportions in children's vaccines maftes converted to body weight. The mixture prepared by Doubleday, featured three pharmacists and three pharmacists who will propose the ypopsifios.I offer was launched in January 2001 to 20,000 dollars, gradually increasing each year and today einai200.000 dollaria.Mechri has not been offered one. Why; http://www.Spontaneous Creation.org Protests for Canadian pandemic vaccines to Afghan detainees 11/11/2009 Protests have revolutionized military decision, under which Afghans detained by Canadian forces in a military base in Afghanistan will receive pandemic vaccine before the general public in Canada. As the Canadian Press, Afghan detainees will be vaccinated with the same priority level as for the Canadians soldiers, beginning on Wednesday, which the Health Minister of Canada called "outrageous." Canadian soldiers said they simply observe the Geneva Convention, under which prisoners are required to receive the same treatment given to soldiers. Military officials said the vaccination of prisoners would help reduce the spread of the pandemic .. Source: Reuters Withdrawn lot pandemic vaccine in Canada 24/11/2009 Withdrawn in Canada a lot of pandemic H1N1 vaccine, and six people had serious allergic reactions, said Department of Public Health (RIA) in the country. The RIA and GlaxosmithKline, the company that manufactures the vaccine Arepanrix, formed in six regions of the country (out of 13) who have received this batch of 172,000 doses to stop using them. As a spokesperson for the RIA, six severe allergic reaction from a lot higher rate than normal. OI FONIADES Hides GENOCIDE THAT THE VACCINE IS "Amplifiers« THYMEROSAL say Mercury - Toxikotato, on reasonable grounds that it causes autism in children and many related behavioral disturbances associated with it. Autism now occurs at a frequency of 1 in 67. While the period before the vaccine was 1 in 20,000 false statement READ AND DECIDE "All six subjects who experienced the reactions have recovered, also said the spokeswoman. He added that those who were vaccinated from this batch of Arepanrix not have to worry about, if not directly experienced an allergic reaction. " Ust ALITES In Hollywood movies of the 70s - 80s, remembers Anna Dollars in 'News' favorite topic was the spread of a deadly virus. scenario like a guinea pig to escape from the laboratory where they were testing a new virus, thus spreading the epidemic in all (American) states and then throughout the world. A fit and conscientious scientist served time in a race to learn the truth, but then face the wall and economic interests of rulers who did not want the disclosures and investigations. In the end, he was coping, he found the antidote, the population is vaccinated and humanity survived.

Scenarios are fiction or reality bottomless as it sounds for a new flu virus, vaccine, and deal with? 1. Actually built on to reduce unemployment; 2. To kill 2.5 dissekatomyria people in the world; When the initiator and Kisigkr ypoloiitis Bush; 3. Bush lost the bousola; 4. Govern us crazy; Answer YOURSELF ... .. "War doctors and billions more from a vaccine ' "The company at the giant pharmaceutical Baxter, Illinois U.S., a patent of the vaccine against new flu virus on August 28, 2008, about a year before the first case! The application, under number 12/199 997, answered by the decision-US number 20090060950A1, which secured the Baxter International patented manufacturing influenza vaccine. Note that in 2001 the same company was accused by an administrative error of strain, which has been publicly recognized, I511 transferred the virus of avian influenza in laboratory units in Europe. Besides the companies manufacturing the vaccine, the dance of billions have come and pharmaceutical companies that support the treatment against the virus and, of course, fiercely attacked by the vaccine. The Roche, the traditional Tamiflu, and GlaxoSmithKline-manufacturing and-vaccine, with Relenza, owned by Novartis IG FARBEN ROCHILDS is located in the top two positions worldwide in the movement of anti-viral drugs. Here's SanoviPasteur in the role of distributor aide Already, however, have released surveys, most recently the British health authorities, who want both drugs powerless in front of new virus. Greek civil war more than a vaccine Five multinational pharmaceutical companies, the Vaxter the Novartis, the GlaxoSmithKline, the Sanovi-Pasteur and Solvay «slaughtered 'in ... apron of the Greek Ministry of Health for a piece of the pie 8 million vaccines ordered, worth 64 million euros! Perhaps the ministers are illiterate and do not are likely to read to PATENT that the vaccine contains 1. 50% Fatal MERCURY 2. CARCINOGENS formaldehyde Life 3 MONTHS 3. ASO3-destroying SKOUALENOIO The immune NSIs TERRITORIAL OF MUNICIPAL 1st KATALAVAINEIS THAT ALL THESE KANOYN ENA H1N1 ASFALESTATO VACCINE FOR HEALTH! Yet, these vaccines are likely to run out to wholesalers, as the Greeks seem particularly reluctant to consider vaccinated. First of all doctors and nurses in NHS hospitals, and pharmacists. According to figures from the ministry, only 10% of medical staff were vaccinated in the first week of vaccination. The reason? "This vaccine is manufactured until mid-May, following two incidents in Florida, so they do not check either the security or effectiveness, and possible unknown side effects in the system of human body, which is currently can not be controlled, "answered the

Assistant Professor of Pediatrics, University of Athens Panagiotis Spyridis. According to the professor, is the first time in the history of medicine "in a vaccine will be produced and the composition contains pieces of the virus, ie the genetic abortion to follow from the compound 3 different materials from animals, birds and pigs and human material . The direct effects from the administration is muscle pain, fever and allergic reaction. "But do not fear them," continues Mr. Spyridon. "Possible damage to the liver, kidneys, heart and general nervous system disease such as Buzz, causing complete paralysis of the nervous system is what we feared." In regard to pregnant women, Professor of Pediatrics is firmly against the vaccination, as no scientist can not rule out a teratogenic, a miscarriage or other serious damage to both the fetus and the mother, such as kidney failure, heart disease and lesions the nervous system and smooth development of the child. METALAXIS DNA pesto purely vre bro! The vaccine ordered by the health authorities of each country and the population is vaccinated at public hospitals and vaccination centers. It traded in the market through pharmacies or private clinics and doctors' surgeries, on the grounds that only on the ten-dose vials, causing new questions. "There will be vaccinated as soon as I do not know what substances enter the body and what I will have implications for the future. There is prescribing the vaccine, or distribution in pharmacies to know what it is, "says the pharmacist about Mrs Helen Kazakos, reflecting the views of the vast majority of colleagues. Mrs. Helen Maltese, the Infectious KEELPNO says in "News" that she was vaccinated, since according to the WHO, the vaccine is 100% secure. "Produced by the same procedure and under the same safety rules that made the vaccine against seasonal flu, and has already given millions of people." LIES LIES LIES A geneticist Mr. Nick Kambouris reveals that especially in the case of laboratory error, preying the "recombination", ie the appearance of a poisonous and more! dangerous virus, and when they somehow infect the existing viruses, which make up the H1N1 virus. According to Mr. Kambouri "addressing the mutant virus will not be easy for the international scientific community, since this phenomenon means that does the change in the inherited genetic material of the virus, the effects are not always controlled or predicted . On the other hand, sounded the alarm on the safe use of vaccines and the general method of preparation, "because these formulations undermine the human gene system, with unknown consequences for the future especially when no one knows exactly substances for their production, as in the case of a vaccine against H1N1 virus, which sounds a lot but nothing has been confirmed to the hazard or safety. "Christos George (Professor of Biochemistry, Department of Biology, University of Patras) Journal Times "The recent news in Canada for the withdrawal of a batch of vaccine as highly dangerous (1) confirms our fears. Furthermore, justice and those scientists and doctors have expressed their opposition, not influenced by the huge economic interests and political bodies like the World Health Organization

(WHO) and health committees of the EU Specifically, the maker Glaxo asked the doctors of Canada to stop the use of a very recent batch of vaccine (October), 170,000 doses, it caused dangerous side effects (respiratory problems, palpitations, skin rashes, etc.) at 500% more than expected. Certainly, evil had been done, because only 900 doses were withdrawn because the others had already been used. Indeed, urban Manitoba and Quebec in Canada investigated three deaths occurred within one week of receiving the vaccine, without the victims belong to any highrisk groups (2, 3). For obvious reasons, the Greek government together with the media (especially television) are hidden from the public that the controversial Canadian vaccine company Glaxo, the Arepanrix H1N1, is totally the same as to the contents of the Pandemrix we sold . This follows the instructions written by the company for both vaccines [4, 5]. Another important issue raised is whether Glaxo and Baxter (which makes the American Celvapan vaccine for the H1N1 virus) was prepared years ago for a pandemic of swine flu, with everything that entails. This is supported by the fact that both companies had submitted patents for such vaccines long before he found the virus in humans for the first time in March-April 2009 in Mexico. In fact, on March 21, 2006 by Glaxo filed patent (number WO2006100109A1), to which the H1N1 virus (page 23) and hazardous components of the vaccine (the Pandemrix), such as squalene adjuvant (page 44) and the toxic mercuric thiomersal (page 12) [6]. Indeed, on February 2, 2007 by Glaxo filed an application to the European Medicines Agency (EMEA) for approval to market the vaccine Pandemrix, which was adopted on May 20, 2008 [7, 8]. The request was for vaccine-matrix («mock-up») with the same composition but with another virus, namely the human H5N1 strain. The same was done by the U.S. company Baxter (a large proportion of shares owned by the notorious former Defense Secretary Bush, Donald Rumsfeld). Specifically, on August 28, 2008 filed for a patent (number 2009/0060950A1 US) for a vaccine that also concerned the H1N1 virus (application page 4) [9]. So when the flu outbreak of fever in 2009, both companies were ready in 2006. Just changed the vaccine-mold with the H1N1 virus and the vaccine produced by WHO-approved in record time! It is indeed strange how the timing of these companies with the advent of swine flu was so ... Perfect! The companies Glaxo and Baxter could be argued that the patents for the manufacture of vaccines only for pigs. But in patents, both companies make a clear reference to use of the vaccine in humans (page 1 of the patent). Another memorable event resulting from the patented Baxter says that as co-inventor of a vaccine scientist named Dr. Kistner Otfried, which ... happens to be used by the WHO as an expert advisor, along with other representatives of pharmaceutical companies, including Dr Norbet Hehme of Glaxo. Specifically, attended a meeting of the WHO in Geneva (on 2-3 November 2005) to "evaluate and develop pandemic influenza vaccines [10] and in Stockholm (August 2007) for preparing a technical report on" public health "regarding influenza vaccines

[11]. This fact is indicative of how the WHO and the pharmaceutical companies act as communicating vessels. "AWAY The DEAD FLESH OF CAPE African Apes 'key component' of the vaccine anything will help ... You think they are exposed PITHIKOUS .... The .... Want to U.S. Mutations in PITHIKOUS;; ;; On the occasion of the upcoming vaccination of most of the world's population, reference should be made to individual components based on which the creation of a vaccine against Influenza A. A petition entechnos mostly concealed by the Greek media, not to become an obstacle to economic plans of ... multinational pharmaceutical companies and causes a natural aversion and mistrust of people, both in the processes of an influenza vaccine, as well as to the actual healing effects that could result in such a vaccination. The new flu vaccine, created under unclear circumstances, since even today the special scientific staffs of the World Health Organization's totally unaware of the biological composition of the virus, the properties of those strains cause the mutation and the reasons that contributed to appearance. Amalgamated 4 different DNA and that means building the vaccine in WEAPON MILITARY LAB SAN BIOLOGICAL WAR AS A HORSE mad IOS VEE, lost by LAB and become the next pandemic. The vaccine consists of a component, which is characterized as a "key component. The creepy this ingredient is dead flesh of African green monkey. Windsurf and Beach Volley METALASEI DNA IN THE DNA of African green monkey !!!!!!!!!! This method and the U.S. patent numbers 5911998: Method for producing influenza vaccine from cell membrane an African green monkey. The whole process of production of the vaccine based on cell membrane of the African monkey kidney, is summarized as follows: "Following the isolation of influenza A virus with special scientific methodology, followed by infection with the monkey virus, which, having originally presenting symptoms of the flu, then develops antibodies to fight it. At the final stage brought by the death in monkeys, that the diseased organs be removed and apodomithoun potent antibodies, in order to start the creation of influenza vaccine. Moreover, it is not random and that people be vaccinated to complement required an affirmation, accepting virtually the same responsibilities of vaccination, and any side effects that may result in the human body, ridding the reality of each responsibility and obligation of the pharmaceutical industry. Another element that creates even highly questionable, and bring a host of reactions in America - the country's creation of the influenza vaccine - from various organizations accuse the pharmaceutical industry to establish atmosphere of terror and manipulation of public opinion around the economic earnings of multinationals, is that the entire process of

production of influenza vaccine is not only headed the World Health Organization, but a company of American interests, famous for the suspicious activity? activists in circles in America, DynCorp. For many in Greece, the company is completely unknown. And this of course is because has achieved everything possible to move underground and their actions are the scenes DynCorp is one of the leading suppliers of private military of the U.S. Government. Among the claims of some of the activities of this company - and what we say, because when involving such interests are withdrawn as insufficient evidence - is the movement of children in child pedophilia ring in Bosnia and the contamination of agricultural crops in Ecuador aerial sprays. Addition, DynCorp allegedly received huge sums from the U.S. Government to guard the borders of America - Mexico, near the area, namely, that appeared in the first case of influenza virus A. The same company is always a record number of patented methods on farming viruses and create vaccines. One of the principal investigators of these methods is Dr Robert H. Purcell, who is also one of the heads of the epidemiological Disease Laboratory, National Institute of Allergy and epidemiological diseases, which, quite accidental, operates under the auspices of the World Health Organization (WHO) or the American government. And the oxymoron is that the company was originally founded as Aeronautics, but over the years expanded into various fields have nothing to do with the original reasons for setting up, acquiring relationships with senior U.S. government and developing strong business ties with them is alleged to have encouraged in recent years particularly from the recent wars? superpower, and the various outbreaks of epidemics in recent years around the globe. Conclusions yours the truth again well below the misinformation and terror. The swine flu, the worst political and corrupt society. All die in a pandemic? What better could happen to really Karamanlis government, and governments of other countries (eg USA) from a pandemic? However, appetite for pumpkin pie, because if this is avian flu, you probably used by scientists to persuade the crowds on huge risk and the threat to mankind from the flu is not the pigs (not to hit the relevant industry), but it is not made by man (regardless of whether a scientist from Australia said ... deliberately? that particular virus was constructed in laboratories in Australia). This flu, then, is more like flu in order, if you think the announcement of the World Health Organization, who assures us that by 2011 the flu will spread to all parts of the world! Such confidence can only have one who sends mail to courier!!! The fact of the spread of influenza, due to its initial complacency (after Mexico), allowing the free movement of American tourists and professionals from the USA to Europe and the world. Great Britain accepted that the degree of penetration of influenza due predominantly to the free entry of American tourists in the country!

That is, everyone who came from the U.S. had the flu? Neither goods for export have been! Although the substance goods are moved very easily, very fast and very convenient for those pharmaceutical companies that manufacture the vaccine against the deadly virus, and of course have already begun to see a crazy influx of money to fund their vaccine orders! Now, why change U.S. law and requires that those who get the vaccine relative to sign and that the pharmaceutical company is not responsible for the preparation, it is indeed strange! Let us, however, in Greece, where the virus has begun to spread at a furious pace and shown entering the country by tourists and Greeks from abroad, while the media across the country dedicated to this subject, which proved poses no risk to anyone. Why the Greek media and burn both do extensive reports while in the U.S. is still considered a disease annually in Europe is treated rather coolly Why try to convince us of the danger inside our home for so strong Why try to tell us something which has already begun to doubt very seriously in many countries around the world and from many major groups of scientists? The answer probably lies in the government to deal settles all Greek citizens to the global pandemic than to Greek tragedy in the economy and (mostly) national issues. It is very good distraction if indeed reached a point where carrying and panic among Greek citizens (by changing the mass), then the government can go in many miserable anti-civil liberties and a host of miserable decline in the national interest. The swine flu has reached first in the brains of politicians, who want very much to turn it into a weapon of propaganda to manipulate agents provocateurs in order to hide their references (lubrication, etc.) to complete the repayment of debts (the sponsors) and offer new guarantees to the Big Brother Black on White House to renew the term of office! Moreover, if the virus manages to mutate and even if done killing, then a new vaccine will be necessary and duly filled the pockets of some specific (eg, former U.S. Defence Secretary Mr Rumsfeld, who is a proven major shareholders of pharmaceutical manufacturing company AntiVirus vaccine)! The work is good! Very good offer and dragon! It's just like reading! And the dragon is the fear of wanting to instil in people, the isolation and delivery of all personal freedom in the hands of people who do not know and certainly not want nor will ever seek to know them. Because the virus is creating problems in the health sector by transferring other pertinent facts health treatment in second gear, maybe the government should live up to its responsibilities and stop the outrages which is unfolding in front of us all by the media, scenarios of horror and terror of chance escapes from ministerial offices (eg Mr Avramopoulos) with emergency plans. But they are all about money or something else? Control the masses, who want to get the current leaders of our country (and the entire planet), as alleged international conspiracy theorists, it might be one which we live and the tragic results of the taste of a few years. Asked to biologist-geneticist if possible to produce

virus which is programmed to activate after a certain time, the answer I got was positive! When we asked if it is possible to activate a virus through a catalyst that can be imported by air or the food chain, the answer was also good! This is not only frightened, but panicked because people want to vaccinate us with an unknown substance (which the U.S. government puts its citizens to sign you will not have financial claims on the manufacturer if any side effects or complications) , which can contain anything not conspiracies, but I think what we all happy to make do, if people become highly controlled and highly controlled one is threatened by a great danger that can not cope alone and leaves the care and responsibility to address the risk to government if the dare to summarize the history of viral fever, which was eagerly waiting to mutate to become the deadliest, we see that knew him, and wanted to come almost as an order. At the World Economic Conference in 2008 in Switzerland, said (and while matters were under discussion was purely financial content) features that: it is surprising that for decades there has been a pandemic hit the world and how perfectly normal it would be right now (ie once was the World Economic Conference)! Besides the danger of vaccinations in general, is a key issue of security of the preparations to be granted in this case in October in schools, as stated by the Greek Government, and the consequences on the health of millions of people both in Greece and in abroad. Already the Austrian journalist Jane Burgermeister in collaboration with experts has gone to lawsuits and claims against those involved (Baxter, World Health Organization, pharmaceutical and other sponsors of the preparations), followed the example of other citizens in France, New Zealand and the U.S. - so far, and started a global movement against forced vaccinations. Private U.S. citizens, in? First• where they have made changes to legislation so that citizens can refuse the vaccination, • but can not exercise its right to damages against company and • threat of forced internment in concentration camps ...? first face the risk of actual pandemic threat of constitutional freedoms and the others follow. Sure I can in a few lines to explain the whole picture, but I give you some basic information to learn and explore themselves, to then see how we can avoid the danger that threatens all of us in the form of vaccines. Bilderberg, vaccines and flu fever According to Bloomberg, Greece has ordered: • 2.000.000 vaccines by the company Glaxo. The reception will begin by mid-September and be completed by December.

3.000.000 vaccines from the company Novartis. The receipt of the 2,000,000 doses will be made until November 15 and will follow in early

January even 1,000,000 doses. • 3.000.000 vaccines by the company Sanofi Pasteur. The reception will begin December 15 and will be completed in early January. The point is that these companies are corespondent in lawsuits and lawsuits that are running against them and the World Health Organization (World Movement against the mandatory vaccination!) In various countries on charges of plotting genocide (International gang plans a massive genocide) The issue is that both we and our children run the same risk in the event of mass vaccination program in October in schools, as announced by the government! The world must refuse to vaccinate at all costs! -Because they will be vaccinated in fact spread the artificial virus stia their communities! In 1918 Greece had survived the black death because residents had not been vaccinated, if an example to many countries abroad this year! But now the danger of vaccines! In New Zealand, are already doing research on the companies manufacturing the vaccine and will not deliver the inhabitants of their country in the clutches of the WHO! they say people there fighting for the global movement against forced vaccinations! In the hope of measuring FIRST TRUTH and substantial concern for the man and Greek citizen's intention to stop the vaccinations! To this end, canceling the licenses of these companies in the country and to begin legal proceedings and investigations by police and in GREECE. After all that, personally, I've decided not to put my blood, which can deliver my brain and my life in the hands of mentally ill people. If my decision is correct and will appear in the future Source: http://www.neagenia.com/gr/?p=1585 European Medicines Agency 7 Westferry Circus, Canary Wharf, London E14 4HB, UK Tel. (44-20) 74 18 84 00 Fax (44-20) 74 18 84 16 E-mail: [email protected] http://www.emea.europa.eu © European Medicines Agency, 2009. Reproduction is authorised provided the source is acknowledged. Reference: EMEA/350155/2009 EMEA/H/C/1015 Propandimiko vaccine Influenza (H5N1) (part of the virus, inactivated, anosoenischymeno) GlaxoSmithKline Biologicals propandimiko influenza vaccine (H5N1) (part of the virus, inactivated, anosoenischymeno) A/VietNam/1194/2004 (NIBRG 14) EPAR summary for the public This document is a summary of the European Public Assessment Report (EPAR). It explains how the Committee for Medicinal Products for Human Use (CHMP) assessed the studies performed, recommendations on how to use the drug. For more information about your medical condition or your treatment, read the leaflet (included in the EPAR) or contact your doctor or pharmacist. For more information about the committee's recommendations, the Scientific Discussion (also part of the EPAR). What is the flu vaccine propandimiko (H5N1) (part of the virus, inactivated, anosoenischymeno) GlaxoSmithKline Biologicals;

The propandimiko influenza vaccine (H5N1) (part of the virus, inactivated, anosoenischymeno) of GlaxoSmithKline Biologicals vaccine is administered by injection. It contains inactivated influenza virus segments which are offset (ie it is dead). The vaccine contains a strain of influenza virus called A/VietNam/1194/2004 NIBRG-14 (H5N1). Cases in which the vaccine is used? The propandimiko influenza vaccine (H5N1) (part of the virus, inactivated, anosoenischymeno) of GlaxoSmithKline Biologicals vaccine is intended for use in adults to protect against flu caused by H5N1 strain of influenza virus type A. The vaccine is based official recommendations only with a prescription. But with that formaldehyde inactivated vaccine has a shelf life the organist three months. Dissolve and absorbs. What happens then; The SON vaccine triggered mob enter freely mutation of human DNA in Two-Ply saurian DNA, beef, chicken or African green monkey. Picked; How to use the vaccine? The vaccine is given as an injection into the muscle of the shoulder in two single doses of which involved at least three weeks. In adults over 80 may need to issue a double dose of vaccine (one injection in each shoulder) followed by a second double dose three weeks later. How does the vaccine? The flu vaccine propandimiko (H5N1) (Section virus, inactivated, but only for three months anosoenischymeno) of GlaxoSmithKline Biologicals is "propandimiko 'vaccine. This is a special type versus strain of influenza that might cause a future pandemic. Pandemic flu occurs when a new strain of flu virus that can spread easily among humans lack immunity (protection) of the population against him. A pandemic could affect many countries and regions in the world. Experts in the health fears that a future influenza pandemic may be caused by the H5N1 strain. The vaccine was developed to provide protection against this type of flu, but the tale is doing just the reverse, metalasei human DNA Vaccines work by 'teaching' the immune system (the body's natural defense) how to defend itself against a disease. This vaccine contains small amounts of HA (proteins from the surface) of the virus H5N1. First, the inactivated virus that will not cause illness. When the vaccine is administered to a person's immune system recognizes the virus as "foreign body" and produces antibodies against it. In this way, when the person is again exposed to the virus, the immune system is able to produce antibodies more quickly. This can help protect against disease caused by a virus. Before use, the vaccine is manufactured by mixing with a suspension containing particles of the virus and an emulsion. The resulting emulsion is then administered by injection. The emulsion also contains a "supporting actor" The formaldehyde eoinai carcinogen, for better response. Windsurf and Beach Volley EXONTOSIS population af Which studied the vaccine? In the main study of the vaccine involving 400 healthy adults aged

between 18 and 60 years and compared the ability of different doses of the vaccine, with or without adjuvant agent to cause the production of antibodies (immunogenicity). Participants were two injections of vaccine containing one of four different doses of HA. Injections given with 21 days difference between them. The main measure of effectiveness were the levels of antibodies against influenza virus in the blood of patients at three different times: before vaccination, the day on which the second injection (day 21) and 21 days later (42nd day). YOU ALL THESE FOR ONLY TAKEN ONE MONTH AND THERE IS NOT SUFFICIENT EXPERIENCE What is the benefit of the vaccine in the studies? According to the criteria formulated by the Committee for Medicinal Products for Human Use (CHMP), to determine an appropriate vaccine should propandimiko cause protective antibody levels at least 70% of persons chorigeitai.APLA AND THE NET WILL Extermination ANYNAMOUS BODIES EPITYGCHANONTAS A REDUCTION population af 2.5 DISSEKATOMYRIA So I phased PEOPLE TO 15% OF UNEMPLOYMENT CF there will be a margin of 10% even WORLD IS GENOCIDE! .. Risks associated with the vaccine? The most common side effects of propandimikou influenza vaccine (H5N1) (part of the virus, inactivated, anosoenischymeno) of GlaxoSmithKline Biologicals (shown in more than 1 in 10 doses of vaccine) are headache, arthralgia (joint pain), myalgia (muscle pain) , egkefalitides epilepsy aftismos, killing embryos reactions at the injection site (hardening, swelling, pain and redness), fever and fatigue (tiredness) .. The vaccine should not be used in people who have experienced anaphylactic shock (severe allergic reaction) to any component of the vaccine or any of the substances may be present in the vaccine in very small quantities, such as eggs, poultry protein, oolefkomatini ( protein found in egg whites), formaldehyde, gentamicin sulfate (antibiotic) and desoxycholiko natrio. Vaccination should be deferred for persons with sudden fever. Why was the vaccine? The Committee for Medicinal Products for Human Use (CHMP) concluded that the benefits of propandimikou influenza vaccine (H5N1) (part of the virus, inactivated, anosoenischymeno) of GlaxoSmithKline Biologicals outweigh the risks associated with it for active immunization against H5N1 subtype of influenza virus A. The committee recommended authorization for the vaccine. Freemasonry IS THE MONEY raised OVER PUBLIC HEALTH Apokodikopoiithike the HIV The genetic code of HIV / AIDS decoded American scientists. They hope that new information will help experts better understand how the virus will eventually lead to the development of more effective therapies. The genetic structure of HIV is complicated enough. Like viruses that cause influenza, hepatitis C and polio, has genetic information in a single chain of

RNA rather than double chain DNA. While the information is encoded in DNA is a rather simple way, the RNA is more complicated because the RNA has the ability to collapses into intricate structures. The U.S. research published in Nature, «unlock" data that may be hidden answers on how the virus. The team from the University of North Carolina at Chapel Hill, said it plans to make small interventions in the genome of the virus. To create our new AIDS? EYCHARISTOUME we will not take The swine flu and the worst Frenetic news from journalists savvy virus spreading panic through our receivers and that leaves a huge gap between the information true and good. There's just hidden a bundle of money from big pharmaceutical industries giants that will serve us as modern Gollum coveted the vaccine. Desperate mothers, teens soft touch, anxious middle-aged and elderly arrostiarides tremble all this invisible danger that threatens to change our lives. And the channels of teachers tromolagneias outweigh the lowly academic physicians and epidemiologists trying unsuccessfully not to dampen the panic settled deeper questions of each presenter Kapsikefalou: How many hours after the fever should go to the emergency room? Take communion Sunday or not? Above : When will we have the first death in the country? Without death there is nothing to sell. What will happen because many of this flu, the issue will play in the channels with the same intensity and the same distortion for a long time. In Mexico, the mask became fashionable, and perhaps even here at noon to see tilekafenedakia valid and Greek efforts, eg pig mask, Tsolias, veligkekas, Karamanlis and Papandreou, a terrorist mask (see first and defending against influenza to be arrested under the new law Mr Dendias) and everything else imaginable that resembles the spirit of our times. Look for coordinated action against the new virus. Private Health Minister following the logic in favor and measures to reduce smoking: a lot of talk and see. How to avoid pesticides in vegetables and fruits O Kostas Akoumianakis, assistant professor of the Department of Horticultural Science, Division of Plant Protection Agricultural University, and Professor of Environmental Chemistry at the Aristotle University of Thessaloniki, Mr. Fitianos give us tips on how to avoid the consumption of fruit and vegetables after .. . pesticides. Eat fruits and vegetables, organic farming or if too expensive, integrated management. The latter are more checks and their production is controlled and monitored frequently for pesticide residues as they are mainly exported products. Wash thoroughly with water, soap and not as many habit-and peel all fruits. In fact, the wash is not only avoid contact pesticide residues and other diseases, such as Toxoplasma, which can be transferred from fruits and vegetables. Wash well as leafy vegetables (lettuce, spinach, etc.) and remove the outer leaves which deposited any deleterious substance. From the garden, the most dangerous-and are more susceptible to pests

and diseases and thus receive more pesticides, are: cucumber, melon, watermelon, the pumpkin. As they mature quickly, the time from spraying until it reaches the plate is often very small and the pesticide can not keep apodomithei. Buy fruit-season vegetables. We are less likely to have pesticide residues, and in the greenhouse growing more diseases and are therefore likely to use more pesticides. This summer they are in season, have better resistance mechanisms. Shop immature fruit and vegetables and leave it outside the refrigerator at a point of light for 3-4 days. That's because most "modern" pesticides have time persistence 7 days. Assuming that it takes about 3 days less to reach a fruit or vegetable from field to home, this is a good solution. Avoid fruits and vegetables from third countries such as Turkey, are likely to have residues of pesticides banned in the EU and thus in Greece. The controls for this possibility is random, while a study by University of Thessaloniki, and found many examples of substances which are legally no longer used in Greece, such as malathion Genetically modified foods reduce fertility (Elias Kadare) A diet based on genetically modified organisms may pose a threat to our reproductive capacity. At least, this research supports the Austrian government, one of the few ever undertaken on this issue. According to the findings of the survey, the fertility of mice whose diet was based on genetically modified corn has decreased significantly compared with mice that ate natural foods. Also, according to the findings of the investigation, mice whose diet was based on genetically modified corn have babies in the third and fourth generation reduced in both number and weight, while mice in the diet were not genetically modified organisms reproduced naturally. "GM foods seem to act as agent of birth control, leading to potential and sterilization. If this reason is not sufficient to close once and the GM industry, then what are waiting for another disaster? "The playing genetic roulette with our food is like playing Russian roulette with consumers and public health." These and many other representatives of Greenpeace said the European Union. The genetically modified hybrid corn (NK 603 x MON 810), examined in this research, which is tolerant to a herbicide and resistant to some insects (moths) are the property of Monsanto. The cultivation and use of food as approved in several countries including USA, Argentina, Japan, the Philippines and South Africa. In Europe and Mexico approved its use in food and feed. The Food Safety Authority (EFSA) of the European Union has given the green light to a genetically modified food as evidenced by research that can be a serious threat to public health. According to statements of the Greek office of the environmental organization Greenpeace «This study proves once again that the mutants are grown and consumed without knowing almost nothing about the long-term effectsAfter finding the excellent complexing ability of EDTA was sought and other synthetic routes of manufacture in

large quantities and at low cost. Today EDTA produced industrially using the following reaction of diamine with formaldehyde and sodium cyanide: The produced ammonia is removed to reduce the formation of a byproduct of another polyaminokarvoxylikou acid, nitrilotriacetic acid (NTA) with the formula N (CH2COOH) 3, which is the main impurity of EDTA. By acidification of the mixture that EDTA is precipitated as relatively insoluble free acid, while the more soluble NTA remains in solution. The ethylenediamine is an industrial raw material for the manufacture of numerous chemicals. The annual output reaches 500,000 metric tons (1998 data). Produced industrially by the reaction of 1,2-dichloroethane with ammonia, or ethylene oxide by catalytic ammoniosi based on the following reactions [Ref 3] Chemical properties of EDTA The EDTA in acid: The EDTA behaves as tetraprotiko acid. It is a moderately strong acid (at least the first two phases dimension) and usually represented as I4EDTA and various salts such as Na2H2EDTA, Na4EDTA, Na2CaEDTA. Also, the usual simple notation as I4Y. The equilibrium separation of EDTA and the corresponding dissociation constants are presented next. It should be noted that EDTA is often referred to as acid exaprotiko considering the protonated forms (with protonation of aminoomadon) as initial forms. Thus, the fully protonated form, I6Y2 + dissociated with I5Y +, so that in I4Y The protonated forms exist only in strongly acidic solutions (pH 50%) of the volume of UF6 in the melt, which should be taken to avoid rupture of the cylinders which kept on increasing the temperature of their contents [Ref 11]. The UF6 is active oxidizing agents and strong acid Lewis. Require special precautions for use and must avoid all contact with skin, and inhalation of vapors. The main reason for the hazardous chemical in the toxicity of uranium and that it reacts with water to form a corrosive and toxic hydrogen fluoride according to the reaction: To UF6 dissolved in organic solvents, but it seems that only solutions in perfluorinated hydrocarbons are stable. It reacts with metals Ni and Al due to the formation of protective layer of insoluble salts of fluorinated metal and can be stored for long periods in well-sealed stainless steel cylinder. Hazards of uranium hexafluoride Depleted uranium hexafluoride (depleted UF6, DUF6) is the main byproduct of the production of enriched uranium. To produce 1 kg of enriched uranium suitable as nuclear fuel (5% U-235) required 11,8 kg of natural uranium and still 10,8 kg of depleted uranium, about 92% of "natural» UF6, entering a plant enriched uranium, leaving as a byproduct. The DUF6 store specially sealed cylinder capacity of 12 tons, which must be constructed and maintained under the strictest standards (ANSI N14.12001). For example, one of the structural requirements that must be kept intact when heated to their content at 800 º C for 30 s [REF 12]. The accumulation of thousands of rolls (from the 1940s until today) DUF6 an economic and environmental problems. The cost of care and maintenance of cylinders is large. In a report by the U.S. Environmental Agency in 2001 indicated that the factories producing enriched uranium, the U.S. (cities Portsmouth, Paducah, and Oak Ridge), 700,000 tons were stored in 57,700 cylinders DUF6 [REF 1 3]. The DUF6. depleted uranium hexafluoride (DUF6) is stored in steel cylinders with a diameter of 1,2 m and a capacity of about 12 tons (a) A vehicle transporting cylinders. (B) outdoor area with a surface coated with cement, which saved thousands of rolls with DUF6. (C) oxidized cylinder which has been leaking the reaction of UF6 with water makes it extremely dangerous compounds because of the toxicity of manufactured products (HF, UO2F2) and modern releases large amounts of heat. The fluoride is irritating the lungs and can cause pulmonary edema, and compounds of uranium are nephrotoxic. They have reported several accidents in factories producing UF6 or uranium enrichment. In 1944, when a heating roller UF6 with steam, broke a roller tubes leading to the release of 200 kg UF6, which reacted with water vapor, thus producing a large quantity of HF that killed two people. In 1978, a UF6 cylinder broke into a store nuclear fuel

without victims. In another incident in 1986, a man died from inhaling gas HF from a cylinder burst, other 31 persons exposed to vapors showed no lesions over time [Ref 14]. Leakage of UF6 cylinders will pollute the aquifer and fluorinated compounds are toxic uranium. This requires continuous monitoring of the status of storage cylinders UF6, which is a dangerous and costly process [Ref 15]. 'Echoun proposed various forms of chemical treatment, such as commitment of HF and F as CaF2 and (DU) in the form of uranium oxide UO2. It should be noted that in addition to chemical hazards in the storage cylinders DUF6 even outdoors, the rolls and a radiological hazard as they are sources emitting neutrons and gamma low level. The neutron emission occurs especially in fluorides of uranium and is due to the side chain of nuclear reactions involving fluorine nuclei. Projectile Uses

nose of

30 depleted

mm

depleted uranium. uranium hexafluoride

Missiles captive head depleted uranium. The DUF6 an association has no utility, but it is the raw material production of metallic depleted uranium (depleted uranium, DU) and its compounds. Given the widespread production of enriched uranium for nuclear fuel and nuclear weapons, it is estimated that current worldwide reserves DU exceed the 1.2 million tons. The "political" use of DU is limited, so for example due to the high specific gravity, as a metal used as a "ballast" stabilization in aircraft and to cases in which the counter must occupy a small volume. A Boeing 747 needs ballast 1500 kg DU. The chemical compounds of uranium sold in their entirety from DU. Oxides of uranium are used as highly Refractory ceramic materials, and color glasses and porcelain. Uranyl nitrate UO2 (NO3) 2 was used previously by the photographic technique and uranyl acetate UO2 (CH3COO) 2 is a classic reagent for detection of sodium, as forming the mixed insoluble salt NaZn (UO2) 3 (CH3COO) 9 • xH2O (x = 6-9). Instead, the military applications of DU metal abound. Used construction Resistance armor military vehicles, as well as bombs and missiles extremely high captive capacity, replacing other more expensive metals with similar properties such as tungsten [REF 16]. The DU combines advantages including: (a) Is a high density (2.5 times more dense than iron) and hardness. When used as a muzzle (nose) missiles and bombs greatly increases the captive capacity, since they can no longer penetrate thick slabs of iron and cement. (B) "Aftoekrignytai. Even without an explosive charge, the uranium projectiles detonate on impact and high temperatures due to the milling of uranium and snap the ignition of dust (oxidation by atmospheric oxygen), which increases their destructive action. (C) low cost, since it is an abundant quantity and essentially useless byproduct of producing nuclear fuel. It appears that the use of DU in the manufacture of conventional weapons systems with the subsequent dispersal of the battlefield can be seen as "profitable" and "effective" way of exemption from at least a

portion of the huge and 'unwanted' stock DUF6 [REF 17, 18]. Regarding the use of "depleted uranium" Form Function uranium U-234 U-235 U-238 Total Natural uranium content of 0.0053% 0.711 99.275 100 Radioactivity, Bq / g * 12356 568 12356 25280 Enriched uranium (3.5% U-235)% containing 3.5 0.02884 99.275 100 Radioactivity, Bq / g 66703 2800 12005 81508 Depleted uranium (by-product of the previous production) 0.2% content 0.0008976 99.799 100 Radioactivity, Bq / g 2076 160 12420 14656 * Becquerel (Bq): Unit of radioactivity equal to the number being divided nuclei of radioactive material in a second Often references to depleted uranium made by the media to suggest that this is a very dangerous and toxic form of uranium. This is not the case. The DU is not substantially different in any physical, chemical or toxicological property from natural uranium. The DU contains only the isotope U-235 (and with it the U-234) in a lower proportion than that in natural uranium and therefore is less radioactive, but that does not mean it is less dangerous the health of those who come into contact with, especially those who inhale particles containing oxides or other compounds. The comparative table shows the typical isotopic composition and activity of various forms of uranium [REF 19].

The compound Aspirin Physical, chemical-economic characteristics [Ref 1] Appearance: Odourless single or white needle crystals. Molecular Formula: C9H8O4 Relative molecular mass: 180.16 Boiling point: decomposes Melting Point: 135 º C (with rapid heating, the melt solidifies at 118 º C) Density: 1,40 g/cm3 Solubility in water: 1 g in 300 mL at 25 º C or 100 mL at 37 º C In other solvents: 1 g in 5 mL of alcohol in 17 mL CHCl3 and 10-15 mL ether. Split into boiling water or in solutions of strong bases. Stable in dry air, gradually hydrolyzed in moist air (acquired odor of acetic acid). Dissociation constant (pKa) = 3,49 (25 º C) LD50 (mice): 1,1 - 1,5 g / kg. It has carcinogenic and reproductive toxicity has not Acetylsalicylic

acid

(Aspirin)

(2-aketoxyvenzoiko acid) Acetylsalicylic acid (Aspirin) (2-acetoxybenzoic acid) "For this publication concerning this precious substance, I have other motives, beyond the hope that it can receive a fair and full trial in all its variety and in each case and situation, and maybe one day the world may benefit from this " (Pastor Edmund Stone, 2 Ιουνίου 1763, announcement before the Royal Society, on the healing properties of willow bark [Ref 8b]) Aspirin, the most widely used drug in the world acetylsalicylic acid (acetylsalicylic acid, ASA), widely known as aspirin (aspirin), is one of the most popular analgesics. The global annual consumption of aspirin was approximately 40,000 tonnes antistoichounperipou to 120 billion tablets of 300 mg [REF 2nd]. In the U.S. estimated that the annual consumption reaches 16,000 tons. Aspirin is used to treat a wide variety of health problems: As a general analgesic and antipyretic (2 to 6 tablets a day) as a precautionary measure cerebral thrombosis (1 tablet a day) against rheumatic fever and arthritis. Also, take precautions against heart attacks. The wide range of pharmaceutical applications of aspirin it difficult to investigate the mechanism of action and only after 1970 was suggested that aspirin and similar drugs interfere with this composition of certain substances that are involved in generation mechanisms of pain and inflammation The main stages in the history of aspirin 400 BC Hippocrates recommends leaves and shavings of the bark of willow trees as analgesics and antipyretics drugs 1763 Notice of Pastor Edmund Stone, before the Royal Society, the potential benefits of using the bark of willow The 1832 French chemist Charles Gerhardt experimenting with salicin and salicylic acid manufacturing 1897, Felix Hoffman, studied experiments Gergardt and "xanaanakalyptei" acetylsalicylic acid 1899 The pharmaceutical Bayer distributes aspirin powder to physicians for administration to patients 1900, Bayer makes aspirin tablets and soluble form of aspirin is the first drug available in this format 1915 Aspirin is available without prescription in tablet form 1948 Lawrence Craven notes that aspirin reduces the chances of heart attack 1971 John Vane theorizes that perhaps the aspirin works by blocking the formation of prostaglandins Historical path of discovery and use of aspirin [Ref 3] In the Old Testament refers to the therapeutic properties of poplar. The

father of medicine Hippocrates (460-377 BC) used a bitter powder from the bark of willow trees, and tea leaves or white willow to relieve patients from pain and fever. Wealthy patients in ancient times ordering drinks poplar bark (a broth prepared by soaking the bark of these trees with vinegar) to address sciatica pain and arthritis. The great physician of the Greco Roman world, Claudius Galen (129-199 AD) studied the antiseptic properties of extracts of the bark of trees and their healing properties on wounds and ulcers. Medicinal products based on willow or poplar used by the Chinese, as well as from American Indians to treat wounds, rheumatism, colds and headaches. The Pedanios Dioscorides (40-90 AD) granted poplar leaf extracts (a mixture with pepper and wine) for the treatment of colic pain. The Gaius Plinius Sekoundos (23-79 AD) in his book of the Naturalis Historia, refers to a substance (presumably derived from salicylic acid) prepared from the powdered bark of willow and poplar. In 1757, the 'English cleric Edmund Stone has highlighted its therapeutic properties of willow bark. He knew that many parishioners, who suffered from rheumatism, used extracts to soothe the pain of the disease. The bitter taste of the bark reminded him of the taste of the bark of the tree of Peru, Peruvian Cinchona officinales (pharmaceutical kinchoni), which was manufactured from an expensive drug (quinine) for the treatment of fever in patients with malaria and apparently assumed some correlation. The Stone presented to the Royal Society for his work on the analgesic properties of this extract of willow bark, which was interested in the medical world. Then searching for an effective analgesic drug to replace this laudanum (an opiate preparation), the sole active analgesic that time. The laudanum had many side effects and frequent use led to addiction. During the Napoleonic Wars (1803-1815), due to the naval blockade, quinine imports from South America were significantly reduced

Old ads for Bayer aspirin. It is worth to note that in the first, along with aspirin, and heroin is advertised as a soothing remedy for cough. Synthesis of salicylic acid and acetylsalicylic acid Adolf Wilhelm Hermann Kolbe (1818 - 1884). German chemical to which is the modern method of preparation of salicylic acid. Known for the electrochemical synthesis of alkanes (reaction Kolbe) The salicylic acid (ohydroxy benzoic acid) is produced in quantities of 60 thousand tonnes annually in the Kolbe method and the dirt cheap raw material phenol, one of the distillates tar [REF 4a]. Phenolic sodium reacts at high temperature (125 º C) and pressure (100 atm) with carbon dioxide and sodium salicylate produced by sulfuric acid yields salicylic acid, according to the following reaction is a reaction known as Kolbe-Schmitt [REF 4b]: Reaction Kolbe Schmitt If used instead of NaOH KOH, favored the formation of mainly parahydroxy benzoic acid, which is used for the manufacture of so-called paravenion (parabens), ie esters of p-hydroxy benzoic acid with various alcohols. The paravenia widely used as biocides and preservatives personal hygiene. The synthesis of aspirin is the raw material salicylic acid and acetic anhydride, which is acetylated phenolic hydroxyl in the molecule. Small amounts of sulfuric or phosphoric acid catalyze the reaction. The preparation is very easy and is usually the pilot exercise in the laboratory of Organic Chemistry undergraduate students. As mentioned in the previous synthesis of acetylsalicylic acid was used by Gerhardt acetyl (CH3COCl), which is drastikotato aketyliotiko average, but is much more volatile liquid (BP 52 º C) of acetic anhydride (s.z . 139 º C), making it more cumbersome laboratory. derivatives of salicylic acid. In nature have been found on several derivatives of salicylic acid and many other prepared in the laboratory. The characteristic properties and uses of salicylic acid and several of the most popular derivatives are summarized below:

Needle crystals of salicylic acid. Right: leaf crystals of acetylsalicylic acid [Ref 4c] Left: Salicylic acid: In old Greek writings referred Chemistry and calicylic acid. Needle crystals, s.t. 157-159 º C. 1 g dissolves in 460 mL water. Irritating to skin, was used as a food preservative (the use of the most banned in most countries). Used in some pharmaceutical preparations for external

use (tylofthora) and particularly for the manufacture of derivatives. Salicin: Glycosides of salicyl alcohol and alcohol beta-glucose. Crystalline substance s.t. 199-202 º C. 1 g dissolved in 23 mL water. The main salicylate derivative of willow bark. Granted in the past as antirheumatic and analgesic. He has very bitter taste. Salicyl alcohol: crystalline substance s.t. 86-87 º C.1 g dissolved in 15 mL water. Hydrolyzate of salicin. Known as saligenini. Used as a local anesthetic. Salicyl aldehyde: oily colorless liquid almond smell, BP 196-197 º C. Slightly soluble in water. Used in perfumery and in organic synthesis. Salikylamidio: White crystalline substance s.t. 140 º C. Used in some pharmaceutical products as an analgesic and antipyretic. Methyl salicylate: oily colorless (yellow when Eve) liquid with a characteristic, rather pleasant odor (though in small concentrations), BP 220-224 º C. Found in various essential oils. Widely used in various analgesic and anti-inflammatory agents (ointments, such as once dimofiiles analgesic rubs preparation for Sloan's), which gives a very characteristic odor. It acts as flogistiko (rubefacient), ie, causing local hyperemia (redness of skin). Salicylate fainylesteras: fusible crystalline substance s.t. 41-43 º C. Is used as an analgesic and antipyretic (known as Salol) and sunscreen. Also used as an additive colored plastic to reduce the discoloration under the effect of sunlight. Acetylsalicylic acid crystalline substance s.t. 135 º C. The most widely used derivative of salicylic acid. The so-called aspirin. Stability of acetylsalicylic acid in pharmaceutical formulations Effect of pH on rate constants hydrolysed-tion of acetylsalicylic acid at 17 º C [REF 5] Acetylsalicylic acid is hydrolyzed easily in an alkaline environment, as in boiling water to the ingredients, ie, salicylic acid and acetic acid. Hydrolyzed slowly under the influence of humidity and are characteristic smell of vinegar (from acetic acid) aspirin tablets exposed to moisture for long periods. Such fragmentation is undesirable because of the formed salicylic acid, which can cause gastric disturbances. In aqueous solutions of acetylsalicylic acid shows greater stability in the range pH 2 to 3 and hydrolyzed rapidly at pH less than 2 or greater than 8 as shown in the adjacent diagram (measured at 17 º C) [Ref 5]. From the graph we can estimate the rate constants of hydrolysis of acetylsalicylic acid at pH 7 is about 0,1 d-1, which corresponds to a half-life of about 7 days. Acetylsalicylic acid in the decision is subject to hydrolysis, especially in slightly alkaline environment of the intestines, from where it is absorbed. Experiments hydrolysis of acetylsalicylic acid with water isotopically enriched oxygen-18 showed that the produced salicylic acid does not

contain O-18, which strengthens the hypothesis of hydrolysis through intramolecular nucleophilic catalysis [Ref 5c]. He has done many studies on factors that could halt or accelerate the hydrolysis of acetylsalicylic acid in pharmaceutical preparations. The influence of different excipients and other drugs in mixed compounds [Ref 6]. According to the U.S. Pharmacopoeia, the maximum permissible level medicines aspirin salicylic acid, depending on the type ranges from 0.3% to 3% [Ref 6d]. Small amounts of free salicylic acid in aspirin medications easily detected by reacting with nitric acid solution of iron (III). The trivalent iron reacts only with free salicylic acid complex providing intense violet color. The determination of salicylic acid in pharmaceutical preparations made in liquid chromatographic. The determination of traces of salicylic acid in acetylsalicylic samples is relatively difficult, since the dissolution of the sample in water and immediately begin its processing. To avoid hydrolysis of acetylsalicylic acid samples used as solvent acetonitrile with a small proportion (1%) of formic acid [Ref 6e]. What also may contain one tablet of aspirin [Ref 6f] Almost never a tablet of medicine is not 100% of the active substance. Indeed, often the latter is only a small percentage of the weight of a tablet. The addition of the active drug substance materials are carriers (excipients), which act as fillers and binders, and holding constant the tablet to the desired size and shape. Other excipients impart a pleasant flavor, but also used for coloring the tablet. Often, the carriers also contain substances that prevent the division of the pharmaceutical substance and regulate the "liberation" or the pace and how "engagement" of the body. In the case of aspirin, acetylsalicylic acid is usually mixed with starch and some water. Often added polyydroxyalkooles (mannitol, sorbitol) and sugars (lactose, sucrose) or synthetic sweeteners (saccharin) and flavor, which help the tablet dissolve faster in water, impart a pleasant taste when chewed (baby aspirin). Other materials act as lubricants (lubricants), which help to prevent the welding of the tablets in different machines during their manufacture. Such materials are hydrogenated vegetable oils, stearic acid and stearates and salts Metabolism of acetylsalicylic acid Acetylsalicylic acid, a weak acid, ionizing little stomach after swallowing the tablet. The solubility is low in the acidic stomach (pH